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Author (up) Aliaga, R.J. doi  openurl
  Title Real-Time Estimation of Zero Crossings of Sampled Signals for Timing Using Cubic Spline Interpolation Type Journal Article
  Year 2017 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.  
  Volume 64 Issue 8 Pages 2414-2422  
  Keywords Digital arithmetic; digital circuits; digital timing; field-programmable gate array (FPGA); interpolation; signal processing algorithms; splines time estimation; time resolution  
  Abstract A scheme is proposed for hardware estimation of the location of zero crossings of sampled signals with subsample resolution for timing applications, which consists of interpolating the signal with a cubic spline near the zero crossing and then finding the root of the resulting polynomial. An iterative algorithm based on the bisection method is presented that obtains one bit of the result per step and admits an efficient digital implementation using fixed-point representation. In particular, the root estimation iteration involves only two additions, and the initial values can be obtained from finite impulse response (FIR) filters with certain symmetry properties. It is shown that this allows online real-time estimation of timestamps in free-running sampling detector systems with improved accuracy with respect to the more common linear interpolation. The method is evaluated with simulations using ideal and real timing signals, and estimates are given for the resource usage and speed of its implementation.  
  Address [Aliaga, Ramon J.] Inst Fis Corpuscular, Paterna 46980, Spain, Email: raalva@upvnet.upv.es  
  Corporate Author Thesis  
  Publisher Ieee-Inst Electrical Electronics Engineers Inc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0018-9499 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000411027700008 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 3301  
Permanent link to this record
 

 
Author (up) Borys, D. et al; Brzezinski, K. doi  openurl
  Title ProTheRaMon-a GATE simulation framework for proton therapy range monitoring using PET imaging Type Journal Article
  Year 2022 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 67 Issue 22 Pages 224002 - 15pp  
  Keywords proton therapy; GATE; Monte Carlo simulations; J-PET; medical imaging  
  Abstract Objective. This paper reports on the implementation and shows examples of the use of the ProTheRaMon framework for simulating the delivery of proton therapy treatment plans and range monitoring using positron emission tomography (PET). ProTheRaMon offers complete processing of proton therapy treatment plans, patient CT geometries, and intra-treatment PET imaging, taking into account therapy and imaging coordinate systems and activity decay during the PET imaging protocol specific to a given proton therapy facility. We present the ProTheRaMon framework and illustrate its potential use case and data processing steps for a patient treated at the Cyclotron Centre Bronowice (CCB) proton therapy center in Krakow, Poland. Approach. The ProTheRaMon framework is based on GATE Monte Carlo software, the CASToR reconstruction package and in-house developed Python and bash scripts. The framework consists of five separated simulation and data processing steps, that can be further optimized according to the user's needs and specific settings of a given proton therapy facility and PET scanner design. Main results. ProTheRaMon is presented using example data from a patient treated at CCB and the J-PET scanner to demonstrate the application of the framework for proton therapy range monitoring. The output of each simulation and data processing stage is described and visualized. Significance. We demonstrate that the ProTheRaMon simulation platform is a high-performance tool, capable of running on a computational cluster and suitable for multi-parameter studies, with databases consisting of large number of patients, as well as different PET scanner geometries and settings for range monitoring in a clinical environment. Due to its modular structure, the ProTheRaMon framework can be adjusted for different proton therapy centers and/or different PET detector geometries. It is available to the community via github (Borys et al 2022).  
  Address [Borys, Damian] Silesian Tech Univ, Dept Syst Biol & Engn, Gliwice, Poland, Email: damin.borys@polsl.pl  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000885248200001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5416  
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Author (up) Carrio, F. doi  openurl
  Title The Data Acquisition System for the ATLAS Tile Calorimeter Phase-II Upgrade Demonstrator Type Journal Article
  Year 2022 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.  
  Volume 69 Issue 4 Pages 687-695  
  Keywords Large Hadron Collider; Data acquisition; Field programmable gate arrays; Clocks; Detectors; Computer architecture; Microprocessors; ATLAS tile calorimeter (TileCal); data acquisition (DAQ) systems; field-programmable gate array (FPGA); high energy physics; high-speed electronics  
  Abstract The tile calorimeter (TileCal) is the central hadronic calorimeter of the ATLAS experiment at the large hadron collider (LHC). In 2025, the LHC will be upgraded leading to the high luminosity LHC (HL-LHC). The HL-LHC will deliver an instantaneous luminosity up to seven times larger than the LHC nominal luminosity. The ATLAS Phase-II upgrade (2025-2027) will accommodate the subdetectors to the HL-LHC requirements. As part of this upgrade, the majority of the TileCal on-detector and off-detector electronics will be replaced using a new readout strategy, where the on-detector electronics will digitize and transmit digitized detector data to the off-detector electronics at the bunch crossing frequency (40 MHz). In the counting rooms, the off-detector electronics will compute reconstructed trigger objects for the first-level trigger and will store the digitized samples in pipelined buffers until the reception of a trigger acceptance signal. The off-detector electronics will also distribute the LHC clock to the on-detector electronics embedded within the digital data stream. The TileCal Phase-II upgrade project has undertaken an extensive research and development program that includes the development of a Demonstrator module to evaluate the performance of the new clock and readout architecture envisaged for the HL-LHC. The Demonstrator module equipped with the latest version of the on-detector electronics was built and inserted into the ATLAS experiment. The Demonstrator module is operated and read out using a Tile PreProcessor (TilePPr) Demonstrator which enables backward compatibility with the present ATLAS Trigger and Data AcQuisition (TDAQ), and the timing, trigger, and command (TTC) systems. This article describes in detail the main hardware and firmware components of the clock distribution and data acquisition systems for the Demonstrator module, focusing on the TilePPr Demonstrator.  
  Address [Carrio, F.] Inst Fis Corpuscular CSIC UV, Paterna 46980, Spain, Email: fernando.carrio@cern.ch  
  Corporate Author Thesis  
  Publisher Ieee-Inst Electrical Electronics Engineers Inc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0018-9499 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000803113800016 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5244  
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Author (up) Herrero, V.; Toledo, J.; Catala, J.M.; Esteve, R.; Gil, A.; Lorca, D.; Monzo, J.M.; Sanchis, F.; Verdugo, A. doi  openurl
  Title Readout electronics for the SiPM tracking plane in the NEXT-1 prototype Type Journal Article
  Year 2012 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A  
  Volume 695 Issue Pages 229-232  
  Keywords Neutrino less double beta decay; Xenon gas TPC; SiPM readout; Front-end electronics; Gated integrator  
  Abstract NEXT is a new experiment to search for neutrinoless double beta decay using a 100 kg radio-pure high-pressure gaseous xenon TPC with electroluminescence readout. A large-scale prototype with a SiPM tracking plane has been built. The primary electron paths can be reconstructed from time-resolved measurements of the light that arrives to the SiPM plane. Our approach is to measure how many photons have reached each SiPM sensor each microsecond with a gated integrator. We have designed and tested a 16-channel front-end board that includes the analog paths and a digital section. Each analog path consists of three different stages: a transimpedance amplifier, a gated integrator and an offset and gain control stage. Measurements show good linearity and the ability to detect single photoelectrons.  
  Address [Herrero, V.; Toledo, J.; Catala, J. M.; Esteve, R.; Monzo, J. M.; Sanchis, F.] Univ Politecn Valencia, CIEMAT, Ctr Mixto, I3M, Valencia 46022, Spain, Email: jtoledo@eln.upv.es  
  Corporate Author Thesis  
  Publisher Elsevier Science Bv Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0168-9002 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000311469900049 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 1237  
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Author (up) Solevi, P.; Magrin, G.; Moro, D.; Mayer, R. doi  openurl
  Title Monte Carlo study of microdosimetric diamond detectors Type Journal Article
  Year 2015 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 60 Issue 18 Pages 7069-7083  
  Keywords ion-beam therapy; microdosimetry; diamonds; GATE  
  Abstract Ion-beam therapy provides a high dose conformity and increased radiobiological effectiveness with respect to conventional radiation-therapy. Strict constraints on the maximum uncertainty on the biological weighted dose and consequently on the biological weighting factor require the determination of the radiation quality, defined as the types and energy spectra of the radiation at a specific point. However the experimental determination of radiation quality, in particular for an internal target, is not simple and the features of ion interactions and treatment delivery require dedicated and optimized detectors. Recently chemical vapor deposition (CVD) diamond detectors have been suggested as ion-beam therapy microdosimeters. Diamond detectors can be manufactured with small cross sections and thin shapes, ideal to cope with the high fluence rate. However the sensitive volume of solid state detectors significantly deviates from conventional microdosimeters, with a diameter that can be up to 1000 times the height. This difference requires a redefinition of the concept of sensitive thickness and a deep study of the secondary to primary radiation, of the wall effects and of the impact of the orientation of the detector with respect to the radiation field. The present work intends to study through Monte Carlo simulations the impact of the detector geometry on the determination of radiation quality quantities, in particular on the relative contribution of primary and secondary radiation. The dependence of microdosimetric quantities such as the unrestricted linear energy L and the lineal energy y are investigated for different detector cross sections, by varying the particle type (carbon ions and protons) and its energy.  
  Address [Solevi, Paola; Magrin, Giulio; Mayer, Ramona] EBG MedAustron, A-2700 Wiener Neustadt, Austria, Email: paola.solevi@ovgu.de  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000361124000004 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2379  
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Author (up) Solevi, P.; Muñoz, E.; Solaz, C.; Trovato, M.; Dendooven, P.; Gillam, J.E.; Lacasta, C.; Oliver, J.F.; Rafecas, M.; Torres-Espallardo, I.; Llosa, G. doi  openurl
  Title Performance of MACACO Compton telescope for ion-beam therapy monitoring: first test with proton beams Type Journal Article
  Year 2016 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 61 Issue 14 Pages 5149-5165  
  Keywords ion-beam therapy; range verification; prompt gamma; Compton camera; GATE  
  Abstract In order to exploit the advantages of ion-beam therapy in a clinical setting, delivery verification techniques are necessary to detect deviations from the planned treatment. Efforts are currently oriented towards the development of devices for real-time range monitoring. Among the different detector concepts proposed, Compton cameras are employed to detect prompt gammas and represent a valid candidate for real-time range verification. We present the first on-beam test of MACACO, a Compton telescope (multi-layer Compton camera) based on lanthanum bromide crystals and silicon photo-multipliers. The Compton telescope was first characterized through measurements and Monte Carlo simulations. The detector linearity was measured employing Na-22 and Am-Be sources, obtaining about 10% deviation from linearity at 3.44 MeV. A spectral image reconstruction algorithm was tested on synthetic data. Point-like sources emitting gamma rays with energy between 2 and 7 MeV were reconstructed with 3-5 mm resolution. The two-layer Compton telescope was employed to measure radiation emitted from a beam of 150 MeV protons impinging on a cylindrical PMMA target. Bragg-peak shifts were achieved via adjustment of the PMMA target location and the resulting measurements used during image reconstruction. Reconstructed Bragg peak profiles proved sufficient to observe peak-location differences within 10 mm demonstrating the potential of the MACACO Compton Telescope as a monitoring device for ion-beam therapy.  
  Address [Solevi, Paola; Munoz, Enrique; Solaz, Carles; Trovato, Marco; Gillam, John E.; Lacasta, Carlos; Oliver, Josep F.; Rafecas, Magdalena; Torres-Espallardo, Irene; Llosa, Gabriela] IFIC CSIC UVEG, Inst Fis Corpuscular, Valencia, Spain, Email: paola.solevi@ovgu.de  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000379555300007 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2754  
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