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Author (up) Perez-Curbelo, J.; Carvalho, C.M.; Schafasand, M.; Rossomme, S.; Llosa, G.; Grevillot, L. doi  openurl
  Title Assessing the delivery error detection sensitivity of a new 2D detector prototype for carbon ion PSQA measurements Type Journal Article
  Year 2026 Publication Journal of Applied Clinical Medical Physics Abbreviated Journal J. Appl. Clin. Med. Phys  
  Volume 27 Issue 5 Pages e70580 - 6pp  
  Keywords Carbon ion patient-specific quality assurance; 2D ionization chamber array; MatriXX AiR; Delivery error detection; Detector sensitivity  
  Abstract Background Particle therapy requires stringent patient-specific quality assurance (PSQA) to validate dose distributions delivered by the system. Purpose This study presents preliminary results on the performance evaluation of the MatriXX AiR 2D ionization-chamber array for patient-specific QA (PSQA) in carbon-ion therapy, comparing measured and planned dose distributions. Methods A series of 10 test cases, including a treatment plan for a box-shaped target (6-cm side length), uniformly covered by the dose and nine patient-specific treatment plans, were assessed. Measurements were conducted at two water equivalent depths using RW3 phantoms: beam entrance and within the Spread-Out Bragg Peak (SOBP). The study examined the detector's ability to detect deviations by systematically modifying treatment plans, comparing the measured and planned dose utilizing gamma index analysis. Results Passing rate analysis revealed depth-dependent sensitivity to treatment plan delivery modifications. Measurements at the entrance depth showed better sensitivity to delivery changes than those taken within the SOBP Conclusions The MatriXX AiR detector demonstrated strong potential for PSQA in carbon ion therapy. These findings support its application in clinical workflows to enhance treatment verification and accuracy.  
  Address [Perez-Curbelo, Javier; Llosa, Gabriela] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: japercur@ific.uv.es  
  Corporate Author Thesis  
  Publisher Wiley Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1526-9914 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001764613300001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 7234  
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