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Author  |
Torres-Sanchez, P.; Lerendegui-Marco, J.; Balibrea-Correa, J.; Babiano-Suarez, V.; Gameiro, B.; Ladarescu, I.; Alvarez-Rodriguez, P.; Daugas, J.M.; Koester, U.; Michelagnoli, C.; Pedrosa-Rivera, M.; Porras, I.; Ruiz-Magaña, M.J.; Ruiz-Ruiz, C.; Domingo-Pardo, C. |
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Title |
The potential of the i-TED Compton camera array for real-time boron imaging and determination during treatments in Boron Neutron Capture Therapy |
Type |
Journal Article |
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Year |
2025 |
Publication |
Applied Radiation and Isotopes |
Abbreviated Journal |
Appl. Radiat. Isot. |
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Volume |
217 |
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Pages |
111649 - 9pp |
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Keywords |
Boron neutron capture therapy; Compton imaging; Detector development; 3D reconstruction |
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Abstract |
This paper explores the adaptation and application of i-TED Compton imagers for real-time dosimetry in Boron Neutron Capture Therapy (BNCT). The i-TED array, previously utilized in nuclear astrophysics experiments at CERN, is being optimized for detecting and imaging 478 keV gamma-rays, critical for accurate BNCT dosimetry. Detailed Monte Carlo simulations were used to optimize the i-TED detector configuration and enhance its performance in the challenging radiation environment typical of BNCT. Additionally, advanced 3D image reconstruction algorithms, including a combination of back-projection and List-Mode Maximum Likelihood Expectation Maximization (LM-MLEM), are implemented and validated through simulations. Preliminary experimental tests at the Institut Laue-Langevin (ILL) demonstrate the potential of i-TED in simplified conditions, with ongoing experiments focusing on testing imaging capabilities in realistic BNCT conditions. |
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Address |
[Torres-Sanchez, Pablo; Lerendegui-Marco, Jorge; Balibrea-Correa, Javier; Babiano-Suarez, Victor; Gameiro, Bernardo; Ladarescu, Ion; Domingo-Pardo, Cesar] Univ Valencia, Inst Fis Corpuscular, CSIC, Valencia, Spain, Email: pablo.torres@ific.uv.es |
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Publisher |
Pergamon-Elsevier Science Ltd |
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Language |
English |
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Original Title |
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Series Volume |
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Edition |
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ISSN |
0969-8043 |
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Notes |
WOS:001420228100001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6515 |
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