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Arganda, E., Marcano, X., Martin Lozano, V., Medina, A. D., Perez, A. D., Szewc, M., et al. (2022). A method for approximating optimal statistical significances with machine-learned likelihoods. Eur. Phys. J. C, 82(11), 993–14pp.
Abstract: Machine-learning techniques have become fundamental in high-energy physics and, for new physics searches, it is crucial to know their performance in terms of experimental sensitivity, understood as the statistical significance of the signal-plus-background hypothesis over the background-only one. We present here a simple method that combines the power of current machine-learning techniques to face high-dimensional data with the likelihood-based inference tests used in traditional analyses, which allows us to estimate the sensitivity for both discovery and exclusion limits through a single parameter of interest, the signal strength. Based on supervised learning techniques, it can perform well also with high-dimensional data, when traditional techniques cannot. We apply the method to a toy model first, so we can explore its potential, and then to a LHC study of new physics particles in dijet final states. Considering as the optimal statistical significance the one we would obtain if the true generative functions were known, we show that our method provides a better approximation than the usual naive counting experimental results.
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Contreras, T., Martins, A., Stanford, C., Escobar, C. O., Guenette, R., Stancari, M., et al. (2023). A method to characterize metalenses for light collection applications. J. Instrum., 18(9), T09004–11pp.
Abstract: Metalenses and metasurfaces are promising emerging technologies that could improve light collection in light collection detectors, concentrating light on small area photodetectors such as silicon photomultipliers. Here we present a detailed method to characterize metalenses to assess their efficiency at concentrating monochromatic light coming from a wide range of incidence angles, not taking into account their imaging quality.
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LHCb Collaboration(Aaij, R. et al), Jaimes Elles, S. J., Jashal, B. K., Martinez-Vidal, F., Oyanguren, A., Rebollo De Miguel, M., et al. (2024). A model-independent measurement of the CKM angle γ in partially reconstructed B±→D∗h± decays with D→K0Sh+h-(h=π,K). J. High Energy Phys., 02(2), 118–30pp.
Abstract: A measurement of CP-violating observables in B-+/-->(DK +/-)-K-& lowast; and B-+/--> D-& lowast;pi(+/-) decays is made where the photon or neutral pion from the D-& lowast;-> D gamma or D-& lowast;-> D pi(0) decay is not reconstructed. The D meson is reconstructed in the self-conjugate decay modes, D -> K-S(0)pi(+)pi(-) or D ->(KSK+K-)-K-0. The distribution of signal yields in the D decay phase space is analysed in a model-independent way. The measurement uses a data sample collected in proton-proton collisions at centre-of-mass energies of 7, 8, and 13 TeV, corresponding to a total integrated luminosity of approximately 9 fb(-1). The B-+/-->(DK +/-)-K-& lowast; and B-+/--> D-& lowast;pi(+/-) CP-violating observables are interpreted in terms of hadronic parameters and the CKM angle gamma, resulting in a measurement of gamma=(92(-17)(+21))degrees. The total uncertainty includes the statistical and systematic uncertainties, and the uncertainty due to external strong-phase inputs.
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Valdes-Cortez, C., Niatsetski, Y., Perez-Calatayud, J., Ballester, F., & Vijande, J. (2022). A Monte Carlo study of the relative biological effectiveness in surface brachytherapy. Med. Phys., 49, 5576–5588.
Abstract: Purpose This work aims to simulate clustered DNA damage from ionizing radiation and estimate the relative biological effectiveness (RBE) for radionuclide (rBT)- and electronic (eBT)-based surface brachytherapy through a hybrid Monte Carlo (MC) approach, using realistic models of the sources and applicators. Methods Damage from ionizing radiation has been studied using the Monte Carlo Damage Simulation algorithm using as input the primary electron fluence simulated using a state-of-the-art MC code, PENELOPE-2018. Two Ir-192 rBT applicators, Valencia and Leipzig, one Co-60 source with a Freiburg Flap applicator (reference source), and two eBT systems, Esteya and INTRABEAM, have been included in this study implementing full realizations of their geometries as disclosed by the manufacturer. The role played by filtration and tube kilovoltage has also been addressed. Results For rBT, an RBE value of about 1.01 has been found for the applicators and phantoms considered. In the case of eBT, RBE values for the Esteya system show an almost constant RBE value of about 1.06 for all depths and materials. For INTRABEAM, variations in the range of 1.12-1.06 are reported depending on phantom composition and depth. Modifications in the Esteya system, filtration, and tube kilovoltage give rise to variations in the same range. Conclusions Current clinical practice does not incorporate biological effects in surface brachytherapy. Therefore, the same absorbed dose is administered to the patients independently on the particularities of the rBT or eBT system considered. The almost constant RBE values reported for rBT support that assumption regardless of the details of the patient geometry, the presence of a flattening filter in the applicator design, or even significant modifications in the photon energy spectra above 300 keV. That is not the case for eBT, where a clear dependence on the eBT system and the characteristics of the patient geometry are reported. A complete study specific for each eBT system, including detailed applicator characteristics (size, shape, filtering, among others) and common anatomical locations, should be performed before adopting an existing RBE value.
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Real, D., Calvo, D., Diaz, A., Salesa Greus, F., & Sanchez Losa, A. (2022). A Narrow Optical Pulse Emitter Based on LED: NOPELED. Sensors, 22(19), 7683–15pp.
Abstract: Light sources emitting short pulses are needed in many particle physics experiments using optical sensors as they can replicate the light produced by the particles being detected and are also an important calibration and test element. This work presents NOPELED, a light source based on LEDs emitting short optical pulses with typical rise times of less than 3 ns and Full Width at Half Maximum lower than 7 ns. The emission wavelength depends on the model of LED used. Several LED models have been characterized in the range from 405 to 532 nm, although NOPELED can work with LED emitting wavelengths outside of that region. While the wavelength is fixed for a given LED model, the intensity and the frequency of the optical pulse can be controlled. NOPELED, which also has low cost and simple operation, can be operated remotely, making it appropriate for either different physics experiments needing in-place light sources such as astrophysical neutrino detectors using photo-multipliers or positron emission tomography devices using scintillation counters, or, beyond physics, applications needing short pulses of light such as protein fluorescence or chemodetection of heavy metals.
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