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Author Penas, J.; Alejo, A.; Bembibre, A.; Apiñaniz, J.I.; Garcia-Garcia, E.; Guerrero, C.; Henares, J.L.; Hernandez-Palmero, I.; Mendez, C.; Millan-Callado, M.A.; Puyuelo-Valdes, P.; Seimetz, M.; Benlliure, J.
Title Production of carbon-11 for PET preclinical imaging using a high-repetition rate laser-driven proton source Type Journal Article
Year 2024 Publication Scientific Reports Abbreviated Journal Sci Rep
Volume (up) 14 Issue 1 Pages 11448 - 12pp
Keywords
Abstract Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range.
Address [Penas, Juan; Alejo, Aaron; Bembibre, Adrian; Benlliure, Jose] Univ Santiago de Compostela, Inst Galego Fis Altas Enerxias IGFAE, Santiago De Compostela 15782, Spain, Email: j.benlliure@usc.es
Corporate Author Thesis
Publisher Nature Portfolio Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2045-2322 ISBN Medium
Area Expedition Conference
Notes WOS:001228252900017 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 6143
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Author Black, K.M. et al; Zurita, J.
Title Muon Collider Forum report Type Journal Article
Year 2024 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume (up) 19 Issue 2 Pages T02015 - 95pp
Keywords Accelerator Applications; Accelerator Subsystems and Technologies; Instrumentation for particle accelerators and storage rings- high energy (linear accelerators, synchrotrons); Large detector systems for particle and astroparticle physics
Abstract A multi-TeV muon collider offers a spectacular opportunity in the direct exploration of the energy frontier. Offering a combination of unprecedented energy collisions in a comparatively clean leptonic environment, a high energy muon collider has the unique potential to provide both precision measurements and the highest energy reach in one machine that cannot be paralleled by any currently available technology. The topic generated a lot of excitement in Snowmass meetings and continues to attract a large number of supporters, including many from the early career community. In light of this very strong interest within the US particle physics community, Snowmass Energy, Theory and Accelerator Frontiers created a cross-frontier Muon Collider Forum in November of 2020. The Forum has been meeting on a monthly basis and organized several topical workshops dedicated to physics, accelerator technology, and detector R&D. Findings of the Forum are summarized in this report.
Address [Black, K. M.; Bose, T.; Dasu, S.; Everaerts, P.; Jia, H.; Lomte, S.; Pinna, D.; Venkatasubramanian, N.; Vuosalo, C.] Univ Wisconsin Madison, Madison, WI USA, Email: sergo@fnal.gov
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:001185309300003 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 6048
Permanent link to this record
 

 
Author LHCb Collaboration (Aaij, R. et al); Jaimes Elles, S.J.; Jashal, B.K.; Martinez-Vidal, F.; Oyanguren, A.; Rebollo De Miguel, M.; Sanderswood, I.; Zhuo, J.
Title Curvature-bias corrections using a pseudomass method Type Journal Article
Year 2024 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume (up) 19 Issue 3 Pages P03010 - 22pp
Keywords Analysis and statistical methods; Detector alignment and calibration methods (lasers, sources, particle-beams); Large detector-systems performance; Performance of High Energy Physics Detectors
Abstract Momentum measurements for very high momentum charged particles, such as muons from electroweak vector boson decays, are particularly susceptible to charge-dependent curvature biases that arise from misalignments of tracking detectors. Low momentum charged particles used in alignment procedures have limited sensitivity to coherent displacements of such detectors, and therefore are unable to fully constrain these misalignments to the precision necessary for studies of electroweak physics. Additional approaches are therefore required to understand and correct for these effects. In this paper the curvature biases present at the LHCb detector are studied using the pseudomass method in proton-proton collision data recorded at centre of mass energy root s = 13 TeV during 2016, 2017 and 2018. The biases are determined using Z -> mu(+)mu(-) decays in intervals defined by the data-taking period, magnet polarity and muon direction. Correcting for these biases, which are typically at the 10(-4) GeV-1 level, improves the Z -> mu(+)mu(-) mass resolution by roughly 18% and eliminates several pathological trends in the kinematic-dependence of the mean dimuon invariant mass.
Address [Egede, U.; Fujii, Y.; Hadavizadeh, T.; Henderson, R. D. L.; Lane, J. J.; Monk, M.; Song, R.; Walton, E. J.; Ward, J. A.] Monash Univ, Sch Phys & Astron, Melbourne, Vic, Australia, Email: seophine.stanislaus@cern.ch
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:001190907900003 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 6057
Permanent link to this record
 

 
Author Guadilla, V.; Algora, A.; Estienne, M.; Fallot, M.; Gelletly, W.; Porta, A.; Rigalleau, L.M.; Stutzmann, J.S.
Title First measurements with a new fl-electron detector for spectral shape studies Type Journal Article
Year 2024 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume (up) 19 Issue 2 Pages P02027 - 21pp
Keywords Detector modelling and simulations I (interaction of radiation with matter; interaction of photons with matter; interaction of hadrons with matter; etc); Instrumentation for radioactive beams (fragmentation devices; fragment and isotope; separators incl. ISOL; isobar separators; ion and atom traps; weak-beam diagnostics; radioactive-beam ion sources); Hybrid detectors; Spectrometers
Abstract The shape of the electron spectrum emitted in /3 decay carries a wealth of information about nuclear structure and fundamental physics. In spite of that, few dedicated measurements have been made of /3 -spectrum shapes. In this work we present a newly developed detector for /3 electrons based on a telescope concept. A thick plastic scintillator is employed in coincidence with a thin silicon detector. The first measurements employing this detector have been carried out with mono -energetic electrons from the high-energy resolution electron -beam spectrometer at Bordeaux. Here we report on the good reproduction of the experimental spectra of mono -energetic electrons using Monte Carlo simulations. This is a crucial step for future experiments, where a detailed Monte Carlo characterization of the detector is needed to determine the shape of the /3 -electron spectra by deconvolution of the measured spectra with the response function of the detector. A chamber to contain two telescope assemblies has been designed for future /3 -decay experiments at the Ion Guide Isotope Separator On -Line facility in Jyvaskyla, aimed at improving our understanding of reactor antineutrino spectra.
Address [Guadilla, V.; Estienne, M.; Fallot, M.; Porta, A.; Rigalleau, L. -m.; Stutzmann, J. -s.] Univ Nantes, Subatech, IMT Atlantique, CNRS,IN2P3, F-44307 Nantes, France, Email: vguadilla@fuw.edu.pl
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:001181748300007 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 6064
Permanent link to this record
 

 
Author LHCb Collaboration (Aaij, R. et al); Jaimes Elles, S.J.; Jashal, B.K.; Martinez-Vidal, F.; Oyanguren, A.; Rebollo De Miguel, M.; Sanderswood, I.; Zhuo, J.
Title Helium identification with LHCb Type Journal Article
Year 2024 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume (up) 19 Issue 2 Pages P02010 - 23pp
Keywords dE/dx detectors; Ion identification systems; Large detector systems for particle and astroparticle physics; Particle identification methods
Abstract The identification of helium nuclei at LHCb is achieved using a method based on measurements of ionisation losses in the silicon sensors and timing measurements in the Outer Tracker drift tubes. The background from photon conversions is reduced using the RICH detectors and an isolation requirement. The method is developed using pp collision data at root s = 13 TeV recorded by the LHCb experiment in the years 2016 to 2018, corresponding to an integrated luminosity of 5.5 fb(-1). A total of around 10(5) helium and antihelium candidates are identified with negligible background contamination. The helium identification efficiency is estimated to be approximately 50% with a corresponding background rejection rate of up to O(10(12)). These results demonstrate the feasibility of a rich programme of measurements of QCD and astrophysics interest involving light nuclei.
Address [Egede, U.; Fujii, Y.; Hadavizadeh, T.; Henderson, R. D. L.; Lane, J. J.; Monk, M.; Song, R.; Walton, E. J.; Ward, J. A.] Monash Univ, Sch Phys & Astron, Melbourne, Vic, Australia, Email: rmoise@cern.ch
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:001185791500006 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 6068
Permanent link to this record