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Author |
Lerendegui-Marco, J.; Balibrea-Correa, J.; Babiano-Suarez, V.; Ladarescu, I.; Domingo-Pardo, C. |
![goto web page (via DOI) doi](img/doi.gif)
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Title |
Towards machine learning aided real-time range imaging in proton therapy |
Type |
Journal Article |
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Year |
2022 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
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Volume ![sorted by Volume (numeric) field, descending order (down)](img/sort_desc.gif) |
12 |
Issue |
1 |
Pages |
2735 - 17pp |
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Abstract |
Compton imaging represents a promising technique for range verification in proton therapy treatments. In this work, we report on the advantageous aspects of the i-TED detector for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that have been specifically designed for neutron-capture nuclear physics experiments, which are characterized by gamma-ray energies spanning up to 5-6 MeV, rather low gamma-ray emission yields and very intense neutron induced gamma-ray backgrounds. Our developments to cope with these three aspects are concomitant with those required in the field of hadron therapy, especially in terms of high efficiency for real-time monitoring, low sensitivity to neutron backgrounds and reliable performance at the high gamma-ray energies. We find that signal-to-background ratios can be appreciably improved with i-TED thanks to its light-weight design and the low neutron-capture cross sections of its LaCl3 crystals, when compared to other similar systems based on LYSO, CdZnTe or LaBr3. Its high time-resolution (CRT similar to 500 ps) represents an additional advantage for background suppression when operated in pulsed HT mode. Each i-TED Compton module features two detection planes of very large LaCl3 monolithic crystals, thereby achieving a high efficiency in coincidence of 0.2% for a point-like 1 MeV gamma-ray source at 5 cm distance. This leads to sufficient statistics for reliable image reconstruction with an array of four i-TED detectors assuming clinical intensities of 10(8) protons per treatment point. The use of a two-plane design instead of three-planes has been preferred owing to the higher attainable efficiency for double time-coincidences than for threefold events. The loss of full-energy events for high energy gamma-rays is compensated by means of machine-learning based algorithms, which allow one to enhance the signal-to-total ratio up to a factor of 2. |
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Address |
[Lerendegui-Marco, Jorge; Balibrea-Correa, Javier; Babiano-Suarez, Victor; Ladarescu, Ion; Domingo-Pardo, Cesar] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: jorge.lerendegui@ific.uv.es |
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Publisher |
Nature Portfolio |
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English |
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ISSN |
2045-2322 |
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Notes |
WOS:000757537100018 |
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no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5136 |
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Permanent link to this record |
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Author |
Doring, C.; Centelles Chulia, S.; Lindner, M.; Schaefer, B.M.; Bartelmann, M. |
![goto web page (via DOI) doi](img/doi.gif)
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Title |
Gravitational wave induced baryon acoustic oscillations |
Type |
Journal Article |
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Year |
2022 |
Publication |
Scipost Physics |
Abbreviated Journal |
SciPost Phys. |
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Volume ![sorted by Volume (numeric) field, descending order (down)](img/sort_desc.gif) |
12 |
Issue |
3 |
Pages |
114 - 47pp |
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Abstract |
We study the impact of gravitational waves originating from a first order phase transition on structure formation. To do so, we perform a second order perturbation analysis in the 1 + 3 covariant framework and derive a wave equation in which second order, adiabatic density perturbations of the photon-baryon fluid are sourced by the gravitational wave energy density during radiation domination and on sub-horizon scales. The scale on which such waves affect the energy density perturbation spectrum is found to be proportional to the horizon size at the time of the phase transition times its inverse duration. Consequently, structure of the size of galaxies and bigger can only be affected in this way by relatively late phase transitions at >= 10(6) s. Using cosmic variance as a bound we derive limits on the strength a and the relative duration (beta/H-*)(-1) of phase transitions as functions of the time of their occurrence which results in a new exclusion region for the energy density in gravitational waves today. We find that the cosmic variance bound forbids only relative long lasting phase transitions, e.g. beta/H-* less than or similar to 6.8 for t(*) approximate to 5 x 10(11 )s, which exhibit a substantial amount of supercooling alpha > 20 to affect the matter power spectrum. |
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Address |
[Doering, Christian; Lindner, Manfred] Max Planck Inst Kernphys, Saupfercheckweg 1, D-69117 Heidelberg, Germany, Email: cdoering@mpi-hd.mpg.de; |
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Scipost Foundation |
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English |
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ISSN |
2542-4653 |
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Notes |
WOS:000782238100035 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5201 |
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Author |
NEXT Collaboration (Henriques, C.A.O. et al); Benlloch-Rodriguez, J.M.; Carcel, S.; Carrion, J.V.; Diaz, J.; Felkai, R.; Kekic, M.; Lopez-March, N.; Martin-Albo, J.; Martinez, A.; Martinez-Lema, G.; Martinez-Vara, M.; Muñoz Vidal, J.; Novella, P.; Palmeiro, B.; Querol, M.; Renner, J.; Romo-Luque, C.; Sorel, M.; Uson, A.; Yahlali, N. |
![goto web page (via DOI) doi](img/doi.gif)
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Title |
Neutral Bremsstrahlung Emission in Xenon Unveiled |
Type |
Journal Article |
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Year |
2022 |
Publication |
Physical Review X |
Abbreviated Journal |
Phys. Rev. X |
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Volume ![sorted by Volume (numeric) field, descending order (down)](img/sort_desc.gif) |
12 |
Issue |
2 |
Pages |
021005 - 23pp |
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Abstract |
We present evidence of non-excimer-based secondary scintillation in gaseous xenon, obtained using both the NEXT-White time projection chamber (TPC) and a dedicated setup. Detailed comparison with first-principle calculations allows us to assign this scintillation mechanism to neutral bremsstrahlung (NBrS), a process that is postulated to exist in xenon that has been largely overlooked. For photon emission below 1000 nm, the NBrS yield increases from about 10(-2) photon/e(-) cm(-1) bar(-1) at pressure-reduced electric field values of 50 V cm(-1) bar(-1) to above 3 x 10(-1) photon/e(-) cm(-1) bar(-1) at 500 V cm(-1) bar(-1). Above 1.5 kV cm(-1) bar(-1), values that are typically employed for electroluminescence, it is estimated that NBrS is present with an intensity around 1 photon/e(-) cm(-1) bar(-1), which is about 2 orders of magnitude lower than conventional, excimer-based electroluminescence. Despite being fainter than its excimeric counterpart, our calculations reveal that NBrS causes luminous backgrounds that can interfere, in either gas or liquid phase, with the ability to distinguish and/or to precisely measure low primary-scintillation signals (S1). In particular, we show this to be the case in the "buffer region, where keeping the electric field below the electroluminescence threshold does not suffice to extinguish secondary scintillation. The electric field leakage in this region should be mitigated to avoid intolerable levels of NBrS emission. Furthermore, we show that this new source of light emission opens up a viable path toward obtaining S2 signals for discrimination purposes in future single-phase liquid TPCs for neutrino and dark matter physics, with estimated yields up to 20-50 photons/e(-) cm(-1). |
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Address |
[Henriques, C. A. O.; Teixeira, J. M. R.; Monteiro, C. M. B.; Fernandes, A. F. M.; Fernandes, L. M. P.; Freitas, E. D. C.; dos Santos, J. M. F.] Univ Coimbra, Dept Phys, ILIBPhys, Rua Larga, P-3004516 Coimbra, Portugal, Email: henriques@uc.pt; |
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Publisher |
Amer Physical Soc |
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English |
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ISSN |
2160-3308 |
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Notes |
WOS:000792590100001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5220 |
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Permanent link to this record |
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Author |
Cranmer, K. et al; Sanz, V. |
![goto web page (via DOI) doi](img/doi.gif)
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Title |
Publishing statistical models: Getting the most out of particle physics experiments |
Type |
Journal Article |
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Year |
2022 |
Publication |
Scipost Physics |
Abbreviated Journal |
SciPost Phys. |
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Volume ![sorted by Volume (numeric) field, descending order (down)](img/sort_desc.gif) |
12 |
Issue |
1 |
Pages |
037 - 55pp |
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Keywords |
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Abstract |
The statistical models used to derive the results of experimental analyses are of incredible scientific value and are essential information for analysis preservation and reuse. In this paper, we make the scientific case for systematically publishing the full statistical models and discuss the technical developments that make this practical. By means of a variety of physics cases – including parton distribution functions, Higgs boson measurements, effective field theory interpretations, direct searches for new physics, heavy flavor physics, direct dark matter detection, world averages, and beyond the Standard Model global fits – we illustrate how detailed information on the statistical modelling can enhance the short- and long-term impact of experimental results. |
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Address |
[Cranmer, Kyle; Held, Alexander] NYU, New York, NY 10003 USA, Email: kyle.cranmer@nyu.edu; |
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Scipost Foundation |
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English |
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2542-4653 |
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Notes |
WOS:000807448000032 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5255 |
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Permanent link to this record |
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Author |
Aarrestad, T. et al; Mamuzic, J.; Ruiz de Austri, R. |
![goto web page (via DOI) doi](img/doi.gif)
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Title |
Benchmark data and model independent event classification for the large hadron collider |
Type |
Journal Article |
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Year |
2022 |
Publication |
Scipost Physics |
Abbreviated Journal |
SciPost Phys. |
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Volume ![sorted by Volume (numeric) field, descending order (down)](img/sort_desc.gif) |
12 |
Issue |
1 |
Pages |
043 - 57pp |
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Keywords |
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Abstract |
We describe the outcome of a data challenge conducted as part of the Dark Machines (https://www.darkmachines.org) initiative and the Les Houches 2019 workshop on Physics at TeV colliders. The challenged aims to detect signals of new physics at the Large Hadron Collider (LHC) using unsupervised machine learning algorithms. First, we propose how an anomaly score could be implemented to define model-independent signal regions in LHC searches. We define and describe a large benchmark dataset, consisting of > 1 billion simulated LHC events corresponding to 10 fb(-1) of proton-proton collisions at a center-of-mass energy of 13 TeV. We then review a wide range of anomaly detection and density estimation algorithms, developed in the context of the data challenge, and we measure their performance in a set of realistic analysis environments. We draw a number of useful conclusions that will aid the development of unsupervised new physics searches during the third run of the LHC, and provide our benchmark dataset for future studies at https://www.phenoMLdata.org. Code to reproduce the analysis is provided at https://github.com/bostdiek/DarkMachines-UnsupervisedChallenge. |
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Address |
[Aarrestad, Thea; Heinrich, Lukas A.; Jawahar, Pratik; Pierini, Maurizio; Touranakou, Mary; Wozniak, Kinga A.] European Org Nucl Res CERN, CH-1211 Geneva 23, Switzerland |
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Scipost Foundation |
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English |
Summary Language |
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2542-4653 |
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Notes |
WOS:000807448000038 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5256 |
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Permanent link to this record |