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Author Peppa, V.; Thomson, R.M.; Enger, S.A.; Fonseca, G.P.; Lee, C.N.; Lucero, J.N.E.; Mourtada, F.; Siebert, F.A.; Vijande, J.; Papagiannis, P.
Title A MC-based anthropomorphic test case for commissioning model-based dose calculation in interstitial breast 192-Ir HDR brachytherapy Type Journal Article
Year 2023 Publication Medical Physics Abbreviated Journal Med. Phys.
Volume (up) 50 Issue 7 Pages 4675-4687
Keywords anthropomorphic phantom; commissioning; HDR brachytherapy; model based dose calculation algorithms; Monte Carlo
Abstract PurposeTo provide the first clinical test case for commissioning of Ir-192 brachytherapy model-based dose calculation algorithms (MBDCAs) according to the AAPM TG-186 report workflow. Acquisition and Validation MethodsA computational patient phantom model was generated from a clinical multi-catheter Ir-192 HDR breast brachytherapy case. Regions of interest (ROIs) were contoured and digitized on the patient CT images and the model was written to a series of DICOM CT images using MATLAB. The model was imported into two commercial treatment planning systems (TPSs) currently incorporating an MBDCA. Identical treatment plans were prepared using a generic Ir-192 HDR source and the TG-43-based algorithm of each TPS. This was followed by dose to medium in medium calculations using the MBDCA option of each TPS. Monte Carlo (MC) simulation was performed in the model using three different codes and information parsed from the treatment plan exported in DICOM radiation therapy (RT) format. Results were found to agree within statistical uncertainty and the dataset with the lowest uncertainty was assigned as the reference MC dose distribution. Data Format and Usage NotesThe dataset is available online at ,. Files include the treatment plan for each TPS in DICOM RT format, reference MC dose data in RT Dose format, as well as a guide for database users and all files necessary to repeat the MC simulations. Potential ApplicationsThe dataset facilitates the commissioning of brachytherapy MBDCAs using TPS embedded tools and establishes a methodology for the development of future clinical test cases. It is also useful to non-MBDCA adopters for intercomparing MBDCAs and exploring their benefits and limitations, as well as to brachytherapy researchers in need of a dosimetric and/or a DICOM RT information parsing benchmark. Limitations include specificity in terms of radionuclide, source model, clinical scenario, and MBDCA version used for its preparation.
Address [Peppa, Vasiliki; Papagiannis, Panagiotis] Natl & Kapodistrian Univ Athens, Med Sch, Med Phys Lab, Athens, Greece, Email: ppapagi@med.uoa.gr
Corporate Author Thesis
Publisher Wiley Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0094-2405 ISBN Medium
Area Expedition Conference
Notes WOS:000989616100001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5529
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Author Bouhova-Thacker, E.; Kostyukhin, V.; Koffas, T.; Liebig, W.; Limper, M.; Piacquadio, G.N.; Prokofiev, K.; Weiser, C.; Wildauer, A.
Title Expected Performance of Vertex Reconstruction in the ATLAS Experiment at the LHC Type Journal Article
Year 2010 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.
Volume (up) 57 Issue 2 Pages 760-767
Keywords Data analysis; data reconstruction; high energy physics; pattern recognition; reconstruction algorithms; tracking; vertex detectors
Abstract In the harsh environment of the Large Hadron Collider at CERN (design luminosity of 10(34) cm(-2) s(-1)) efficient reconstruction of vertices is crucial for many physics analyses. Described in this paper is the expected performance of the vertex reconstruction used in the ATLAS experiment. The algorithms for the reconstruction of primary and secondary vertices as well as for finding photon conversions and vertex reconstruction in jets are described. The implementation of vertex algorithms which follows a very modular design based on object-oriented C++ is presented. A user-friendly concept allows event reconstruction and physics analyses to compare and optimize their choice among different vertex reconstruction strategies. The performance of implemented algorithms has been studied on a variety of Monte Carlo samples and results are presented.
Address [Bouhova-Thacker, Eva] Univ Lancaster, Lancaster LA1 4YB, England, Email: bouhova@mail.cern.ch
Corporate Author Thesis
Publisher Ieee-Inst Electrical Electronics Engineers Inc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0018-9499 ISBN Medium
Area Expedition Conference
Notes ISI:000276679200006 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 260
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Author Aliaga, R.J.
Title Real-Time Estimation of Zero Crossings of Sampled Signals for Timing Using Cubic Spline Interpolation Type Journal Article
Year 2017 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.
Volume (up) 64 Issue 8 Pages 2414-2422
Keywords Digital arithmetic; digital circuits; digital timing; field-programmable gate array (FPGA); interpolation; signal processing algorithms; splines time estimation; time resolution
Abstract A scheme is proposed for hardware estimation of the location of zero crossings of sampled signals with subsample resolution for timing applications, which consists of interpolating the signal with a cubic spline near the zero crossing and then finding the root of the resulting polynomial. An iterative algorithm based on the bisection method is presented that obtains one bit of the result per step and admits an efficient digital implementation using fixed-point representation. In particular, the root estimation iteration involves only two additions, and the initial values can be obtained from finite impulse response (FIR) filters with certain symmetry properties. It is shown that this allows online real-time estimation of timestamps in free-running sampling detector systems with improved accuracy with respect to the more common linear interpolation. The method is evaluated with simulations using ideal and real timing signals, and estimates are given for the resource usage and speed of its implementation.
Address [Aliaga, Ramon J.] Inst Fis Corpuscular, Paterna 46980, Spain, Email: raalva@upvnet.upv.es
Corporate Author Thesis
Publisher Ieee-Inst Electrical Electronics Engineers Inc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0018-9499 ISBN Medium
Area Expedition Conference
Notes WOS:000411027700008 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 3301
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Author AGATA Collaboration (Akkoyun, S. et al); Algora, A.; Barrientos, D.; Domingo-Pardo, C.; Egea, F.J.; Gadea, A.; Huyuk, T.; Kaci, M.; Mendez, V.; Rubio, B.; Salt, J.; Tain, J.L.
Title AGATA-Advanced GAmma Tracking Array Type Journal Article
Year 2012 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume (up) 668 Issue Pages 26-58
Keywords AGATA; gamma-Ray spectroscopy; gamma-Ray tracking; HPGe detectors; Digital signal processing; Pulse-shape and gamma-ray tracking algorithms; Semiconductor detector performance and simulations
Abstract The Advanced GAmma Tracking Array (AGATA) is a European project to develop and operate the next generation gamma-ray spectrometer. AGATA is based on the technique of gamma-ray energy tracking in electrically segmented high-purity germanium crystals. This technique requires the accurate determination of the energy, time and position of every interaction as a gamma ray deposits its energy within the detector volume. Reconstruction of the full interaction path results in a detector with very high efficiency and excellent spectral response. The realisation of gamma-ray tracking and AGATA is a result of many technical advances. These include the development of encapsulated highly segmented germanium detectors assembled in a triple cluster detector cryostat, an electronics system with fast digital sampling and a data acquisition system to process the data at a high rate. The full characterisation of the crystals was measured and compared with detector-response simulations. This enabled pulse-shape analysis algorithms, to extract energy, time and position, to be employed. In addition, tracking algorithms for event reconstruction were developed. The first phase of AGATA is now complete and operational in its first physics campaign. In the future AGATA will be moved between laboratories in Europe and operated in a series of campaigns to take advantage of the different beams and facilities available to maximise its science output. The paper reviews all the achievements made in the AGATA project including all the necessary infrastructure to operate and support the spectrometer.
Address [Boston, A. J.; Boston, H. C.; Colosimo, S.; Cooper, R. J.; Cresswell, J. R.; Dimmock, M. R.; Filmer, F.; Grint, A. N.; Harkness, L. J.; Judson, D. S.; Mather, A. R.; Moon, S.; Nelson, L.; Nolan, P. J.; Norman, M.; Oxley, D. C.; Rigby, S.; Sampson, J.; Scraggs, D. P.; Seddon, D.; Slee, M.; Stanios, T.; Thornhill, J.; Unsworth, C.; Wells, D.] Univ Liverpool, Oliver Lodge Lab, Liverpool L69 7ZE, Merseyside, England, Email: a.j.boston@liverpool.ac.uk
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000300864200005 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 923
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Author AGATA Collaboration (Crespi, F.C.L. et al); Gadea, A.
Title Response of AGATA segmented HPGe detectors to gamma rays up to 15.1 MeV Type Journal Article
Year 2013 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume (up) 705 Issue Pages 47-54
Keywords AGATA; Gamma-ray spectroscopy; Gamma-ray tracking; HPGe detectors; Pulse-shape and gamma-ray tracking algorithms; Semiconductor detector performance and simulations
Abstract The response of AGATA segmented HPGe detectors to gamma rays in the energy range 2-15 MeV was measured. The 15.1 MeV gamma rays were produced using the reaction d(B-11,n gamma)C-12 at E-beam=19.1 MeV, while gamma rays between 2 and 9 MeV were produced using an Am-Be-Fe radioactive source. The energy resolution and linearity were studied and the energy-to-pulse-height conversion resulted to be linear within 0.05%.Experimental interaction multiplicity distributions are discussed and compared with the results of Geant4 simulations. It is shown that the application of gamma-ray tracking allows a suppression of background radiation caused by n-capture in Ge nuclei. Finally the Doppler correction for the 15.1 MeV gamma line, performed using the position information extracted with Pulse-shape analysis is discussed.
Address [Crespi, F. C. L.; Avigo, R.; Camera, F.; Bottoni, S.; Bracco, A.; Ceruti, S.; Giaz, A.; Leoni, S.; Nicolini, R.; Pellegri, L.; Riboldi, S.; Vandone, V.] Univ Milan, Dipartimento Fis, I-20133 Milan, Italy, Email: fabio.crespi@mi.infn.it
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000314826000009 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1329
Permanent link to this record