Bout, R., Busto, J., Cecchini, V., Charpentier, P., Chapellier, M., Dastgheibi-Fard, A., et al. (2024). Perspectives of a single-anode cylindrical chamber operating in ionization mode and high gas pressure. Eur. Phys. J. C, 84(5), 512–14pp.
Abstract: As part of the R2D2 (Rare Decays with Radial Detector) R &D, the use of a gas detector with a spherical or cylindrical cathode, equipped with a single anode and operating at high pressure, was studied for the search of rare phenomena such as neutrinoless double-beta decay. The presented measurements were obtained with a cylindrical detector, covering gas pressures ranging from 1 to 10 bar in argon and 1 to 6 bar in xenon, using both a point-like source of 210 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{210} $$\end{document} Po (5.3 MeV alpha \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\alpha $$\end{document} ) and a diffuse source of 222 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{222}$$\end{document} Rn (5.5 MeV alpha \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\alpha $$\end{document} ). Analysis and interpretation of the data were developed using the anodic current waveform. Similar detection performances were achieved with both gases, and comparable energy resolutions were measured with both sources. As long as the purity of the gas was sufficient, no significant degradation of the measured energy was observed by increasing the pressure. At the highest operating pressure, an energy resolution better than 1.5% full-width at half-maximum (FWHM) was obtained for both gaseous media, although optimal noise conditions were not reached.
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ATLAS Collaboration(Abat, E. et al), Bernabeu Verdu, J., Castillo Gimenez, V., Costa, M. J., Escobar, C., Ferrer, A., et al. (2011). Photon reconstruction in the ATLAS Inner Detector and Liquid Argon Barrel Calorimeter at the 2004 Combined Test Beam. J. Instrum., 6, P04001–40pp.
Abstract: The reconstruction of photons in the ATLAS detector is studied with data taken during the 2004 Combined Test Beam, where a full slice of the ATLAS detector was exposed to beams of particles of known energy at the CERN SPS. The results presented show significant differences in the longitudinal development of the electromagnetic shower between converted and unconverted photons as well as in the total measured energy. The potential to use the reconstructed converted photons as a means to precisely map the material of the tracker in front of the electromagnetic calorimeter is also considered. All results obtained are compared with a detailed Monte-Carlo simulation of the test-beam setup which is based on the same simulation and reconstruction tools as those used for the ATLAS detector itself.
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Irles, A., Marquez, J. P., Pöschl, R., Richard, F., Saibel, A., Yamamoto, H., et al. (2024). Probing gauge-Higgs unification models at the ILC with quark-antiquark forward-backward asymmetry at center-of-mass energies above the Z mass. Eur. Phys. J. C, 84(5), 537–17pp.
Abstract: The International Linear Collider (ILC) will allow the precise study of e(-)e(+)-> q (q) over bar interactions at different center-of-mass energies from the Z-pole to 1 TeV. In this paper, we discuss the experimental prospects for measuring differential observables in e(-)e(+)-> b (b) over bar and e(-)e(+) -> c (c) over bar at the ILC baseline energies, 250 and 500 GeV. The study is based on full simulation and reconstruction of the International Large Detector (ILD) concept. Two gauge-Higgs unification models predicting new high-mass resonances beyond the Standard Model are discussed. These models predict sizable deviations of the forward-backward observables at the ILC running above the Z mass and with longitudinally polarized electron and positron beams. The ability of the ILC to probe these models via high-precision measurements of the forward-backward asymmetry is discussed. Alternative scenarios at other energies and beam polarization schemes are also discussed, extrapolating the estimated uncertainties from the two baseline scenarios.
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Rossi, R. R., Sanchez Garcia, G., & Tortola, M. (2024). Probing nuclear properties and neutrino physics with current and future CEνNS experiments. Phys. Rev. D, 109(9), 095044–17pp.
Abstract: The recent observation of coherent elastic neutrino-nucleus scattering (CEvNS) with neutrinos from pion decay at rest (N-DAR) sources by the COHERENT Collaboration has raised interest in this process in the search for new physics. Unfortunately, current uncertainties in the determination of nuclear parameters relevant to those processes can hide new physics effects. This is not the case for processes involving lower-energy neutrino sources such as nuclear reactors. Note, however, that a CEvNS measurement with reactor neutrinos depends largely on a (still-missing) precise determination of the quenching factor at very low energies, making its observation more challenging. In the upcoming years, once this signal is confirmed, a combined analysis of N-DAR and reactor CEvNS experiments will be very useful to probe particle and nuclear physics, with a reduced dependence on nuclear uncertainties. In this work, we explore this idea by simultaneously testing the sensitivity of current and future CEvNS experiments to neutrino nonstandard interactions (NSIs) and the neutron root mean square (rms) radius, considering different neutrino sources as well as several detection materials. We show how the interplay between future reactor and accelerator CEvNS experiments can help to get robust constraints on the neutron rms and to break degeneracies between the NSI parameters. Our forecast could be used as a guide to optimize the experimental sensitivity to the parameters under study.
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Penas, J., Alejo, A., Bembibre, A., Apiñaniz, J. I., Garcia-Garcia, E., Guerrero, C., et al. (2024). Production of carbon-11 for PET preclinical imaging using a high-repetition rate laser-driven proton source. Sci Rep, 14(1), 11448–12pp.
Abstract: Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range.
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Barenboim, G., Calatayud-Cadenillas, A. M., Gago, A. M., & Ternes, C. A. (2024). Quantum decoherence effects on precision measurements at DUNE and T2HK. Phys. Lett. B, 852, 138626–11pp.
Abstract: We investigate the potential impact of neutrino quantum decoherence on the precision measurements of standard neutrino oscillation parameters in the DUNE and T2HK experiments. We show that the measurement of delta(CP), sin(2) theta(13) and sin(2) theta(23) is stronger effected in DUNE than in T2HK. On the other hand, DUNE would have a better sensitivity than T2HK to observe decoherence effects. By performing a combined analysis of DUNE and T2HK we show that a robust measurement of standard parameters would be possible, which is not guaranteed with DUNE data alone.
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Gil-Dominguez, F., & Molina, R. (2024). Quark mass dependence of the D*s0 (2317) and D s1 (2460) resonances. Phys. Rev. D, 109(9), 096002–17pp.
Abstract: We determine the quark mass dependence-light and heavy-of the D*s0(2317) and Ds1(2460) properties, such as, mass, coupling to D(*)K, scattering lengths and compositeness, from a global analysis I = 0 for different boosts and two pion masses. The formalism is based in the local hidden-gauge interaction of Weinberg-Tomozawa type which respects both chiral and heavy quark spin symmetries, supplemented by a term that takes into account the D(*)K coupling to a bare cs<overline> component. The isospin violating decay of the D*s0(2317) -> D+s pi 0 is also evaluated.
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Di Gregorio, E., Staelens, M., Hosseinkhah, N., Karimpoor, M., Liburd, J., Lim, L., et al. (2024). Raman Spectroscopy Reveals Photobiomodulation-Induced α-Helix to β-Sheet Transition in Tubulins: Potential Implications for Alzheimer's and Other Neurodegenerative Diseases. Nanomaterials, 14(13), 1093–21pp.
Abstract: In small clinical studies, the application of transcranial photobiomodulation (PBM), which typically delivers low-intensity near-infrared (NIR) to treat the brain, has led to some remarkable results in the treatment of dementia and several neurodegenerative diseases. However, despite the extensive literature detailing the mechanisms of action underlying PBM outcomes, the specific mechanisms affecting neurodegenerative diseases are not entirely clear. While large clinical trials are warranted to validate these findings, evidence of the mechanisms can explain and thus provide credible support for PBM as a potential treatment for these diseases. Tubulin and its polymerized state of microtubules have been known to play important roles in the pathology of Alzheimer's and other neurodegenerative diseases. Thus, we investigated the effects of PBM on these cellular structures in the quest for insights into the underlying therapeutic mechanisms. In this study, we employed a Raman spectroscopic analysis of the amide I band of polymerized samples of tubulin exposed to pulsed low-intensity NIR radiation (810 nm, 10 Hz, 22.5 J/cm2 dose). Peaks in the Raman fingerprint region (300-1900 cm-1)-in particular, in the amide I band (1600-1700 cm-1)-were used to quantify the percentage of protein secondary structures. Under this band, hidden signals of C=O stretching, belonging to different structures, are superimposed, producing a complex signal as a result. An accurate decomposition of the amide I band is therefore required for the reliable analysis of the conformation of proteins, which we achieved through a straightforward method employing a Voigt profile. This approach was validated through secondary structure analyses of unexposed control samples, for which comparisons with other values available in the literature could be conducted. Subsequently, using this validated method, we present novel findings of statistically significant alterations in the secondary structures of polymerized NIR-exposed tubulin, characterized by a notable decrease in alpha-helix content and a concurrent increase in beta-sheets compared to the control samples. This PBM-induced alpha-helix to beta-sheet transition connects to reduced microtubule stability and the introduction of dynamism to allow for the remodeling and, consequently, refreshing of microtubule structures. This newly discovered mechanism could have implications for reducing the risks associated with brain aging, including neurodegenerative diseases like Alzheimer's disease, through the introduction of an intervention following this transition.
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Aristizabal Sierra, D., De Romeri, V., & Ternes, C. A. (2024). Reactor neutrino background in next-generation dark matter detectors. Phys. Rev. D, 109(11), 115026–7pp.
Abstract: Third -generation dark matter detectors will be fully sensitive to the 8 B solar neutrino flux. Because of this, the characterization of such a background has been the subject of extensive analyses over the last few years. In contrast, little is known about the impact of reactor neutrinos. In this paper, we report on the implications of such a flux for dark matter direct -detection searches. We consider five potential detector deployment sites envisioned by the recently established XLZD Consortium: SURF, SNOLAB, Kamioka, LNGS, and Boulby. By using public reactor data, we construct five reactor clusters -involving about 100 currently operating commercial nuclear reactors each -and determine the net neutrino flux at each detector site. Assuming a xenon -based detector and a 50 ton -year exposure, we show that in all cases the neutrino event rate may be sizable, depending on energy recoil thresholds. Of all possible detector sites, SURF and LNGS are those with the smallest reactor neutrino background. On the contrary, SNOLAB and Boulby are subject to the strongest reactor neutrino fluxes, with Kamioka being subject to a more moderate background. Our findings demonstrate that reactor neutrino fluxes should be taken into account in the next round of dark matter searches. We argue that this background may be particularly relevant for directional detectors, provided they meet the requirements we have employed in this analysis.
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Richard, J. M., Valcarce, A., & Vijande, J. (2024). Resonances in the Quark Model. Few-Body Syst., 65(3), 71–11pp.
Abstract: A discussion is presented of the estimates of the energy and width of resonances in constituent models, with focus on the tetraquark states containing heavy quarks.
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