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Author Scandale, W. et al; Lari, L. doi  openurl
  Title Optimization of the crystal assisted collimation of the SPS beam Type Journal Article
  Year 2013 Publication Physics Letters B Abbreviated Journal Phys. Lett. B  
  Volume 726 Issue 1-3 Pages 182-186  
  Keywords Accelerator; Beam collimation; Crystal; Channeling  
  Abstract The possibility for optimization of crystal assisted collimation has been studied at the CERN SPS for stored beams of protons and Pb ions with 270 GeV/c per unit charge. A bent silicon crystal used as a primary collimator deflects halo particles in the channeling regime, directing them into a tungsten absorber. In channeling conditions a strong reduction of off-momentum particle numbers produced in the crystal and absorber, which form collimation leakage, has been observed in the first high dispersion (HD) area downstream. The present study shows that the collimation leakage is minimal for some values of the absorber offset relative to the crystal. The optimal offset value is larger for Pb ions because of their considerably larger ionization losses in the crystal, which cause large increases of particle betatron oscillation amplitudes. The optimal absorber offset allows obtaining maximal efficiency of crystal-assisted collimation.  
  Address [Scandale, W.; Arduini, G.; Butcher, M.; Cerutti, F.; Gilardoni, S.; Lari, L.; Lechner, A.; Losito, R.; Masi, A.; Mereghetti, A.; Metral, E.; Mirarchi, D.; Montesano, S.; Redaelli, S.; Schoofs, P.; Smirnov, G.] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland, Email: alexander.taratin@cern.ch  
  Corporate Author Thesis  
  Publisher Elsevier Science Bv Place of Publication Editor  
  Language English Summary Language (up) Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0370-2693 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000326482200020 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1694  
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Author Resta-Lopez, J. doi  openurl
  Title Nonlinear protection of beam delivery systems for multi-TeV linear colliders Type Journal Article
  Year 2013 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.  
  Volume 8 Issue Pages P11010 - 19pp  
  Keywords Beam Optics; Beam dynamics; Accelerator Subsystems and Technologies; Accelerator modelling and simulations (multi-particle dynamics; single-particle dynamics)  
  Abstract The post-linac energy collimation system of future e(+)e(-) multi-TeV linear colliders is designed to fulfil an essential function of protection of the Beam Delivery System (BDS) against miss-steered or errant beams likely generated by failure modes in the main linac. For the case of the Compact Linear Collider (CLIC), the energy collimators are required to withstand the impact of a full bunch train in case of failure. This condition makes the design of the energy collimation system especially challenging, if we take into account the need to dispose of an unprecedented transverse beam energy density per beam of the order of GJ/mm(2), when assuming the nominal CLIC beam parameters at 3 TeV centre-of-mass energy, which translates into an extremely high damage potential of uncontrolled beams. This leads to research activities involving new collimator materials and novel collimation techniques. The increase of the transverse spot size at the collimators using nonlinear magnets is a potential solution to guarantee the survival of the collimators. In this paper we present an alternative nonlinear optics based on a multipole magnet pair for energy collimation. In order to preserve an acceptable luminosity performance, we carefully study the general conditions for self-cancellation of optical aberrations between two multipoles. This nonlinear optics scheme is adapted to the requirements of the post-linac energy collimation system for the CLIC BDS, and its performance is investigated by means of beam tracking simulations. Although applied to the CLIC case, this nonlinear protection system could be adapted to other future colliders.  
  Address Univ Valencia, Inst Fis Corpuscular IFIC, Ctr Mixto CSIC, Inst Invest Paterna, Valencia 46071, Spain, Email: resta@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language (up) Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1748-0221 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000329193500035 Approved no  
  Is ISI yes International Collaboration  
  Call Number IFIC @ pastor @ Serial 1697  
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Author Piersanti, L.; Bellini, F.; Bini, F.; Collamati, F.; De Lucia, E.; Durante, M.; Faccini, R.; Ferroni, F.; Fiore, S.; Iarocci, E.; La Tessa, C.; Marafini, M.; Mattei, I.; Patera, V.; Ortega, P.G.; Sarti, A.; Schuy, C.; Sciubba, A.; Vanstalle, M.; Voena, C. doi  openurl
  Title Measurement of charged particle yields from PMMA irradiated by a 220 MeV/u C-12 beam Type Journal Article
  Year 2014 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 59 Issue 7 Pages 1857-1872  
  Keywords drift chamber; LYSO; hadrontherapy; carbon ion beam; dose monitoring  
  Abstract The radiation used in hadrontherapy treatments interacts with the patient body producing secondary particles, either neutral or charged, that can be used for dose and Bragg peak monitoring and to provide a fast feedback on the treatment plans. Recent results obtained from the authors on simplified setups (mono-energetic primary beams interacting with homogeneous tissue like target) have already indicated the correlation that exists between the flux of these secondaries coming from the target (e.g. protons and photons) and the position of the primary beam Bragg peak. In this paper, the measurements of charged particle fluxes produced by the interaction of a 220 MeV/u carbon ion beam at GSI, Darmstadt, with a polymethyl methacrylate target are reported. The emission region of protons (p), deuterons (d) and tritons (t) has been characterized using a drift chamber while the particle time-of-flight, used to compute the kinetic energy spectra, was measured with a LYSO scintillator.The energy released in the LYSO crystal was used for particle identification purposes. The measurements were repeated with the setup at 60 degrees and 90 degrees with respect to the primary beam direction. The accuracy on the fragments emission profile reconstruction and its relationship with the Bragg peak position have been studied. Based on the acquired experimental evidence, a method to monitor the dose profile and the position of the Bragg peak inside the target is proposed.  
  Address [Piersanti, L.; De Lucia, E.; Iarocci, E.; Mattei, I.; Sarti, A.] Ist Nazl Fis Nucl, Lab Nazl Frascati, I-00044 Frascati, Italy, Email: vincenzo.patera@lnf.infn.it  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language (up) Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000333186200020 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1735  
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Author Anderson, L. et al; Mena, O. url  doi
openurl 
  Title The clustering of galaxies in the SDSS-III Baryon Oscillation Spectroscopic Survey: measuring D-A and H at z=0.57 from the baryon acoustic peak in the Data Release 9 spectroscopic Galaxy sample Type Journal Article
  Year 2014 Publication Monthly Notices of the Royal Astronomical Society Abbreviated Journal Mon. Not. Roy. Astron. Soc.  
  Volume 439 Issue 1 Pages 83-101  
  Keywords cosmological parameters; cosmology: observations; dark energy; distance scale; large scale structure of Universe  
  Abstract We present measurements of the angular diameter distance to and Hubble parameter at z = 0.57 from the measurement of the baryon acoustic peak in the correlation of galaxies from the Sloan Digital Sky Survey III Baryon Oscillation Spectroscopic Survey. Our analysis is based on a sample from Data Release 9 of 264 283 galaxies over 3275 square degrees in the redshift range 0.43 < z < 0.70. We use two different methods to provide robust measurement of the acoustic peak position across and along the line of sight in order to measure the cosmological distance scale. We find D-A(0.57) = 1408 +/- 45 Mpc and H(0.57) = 92.9 +/- 7.8 km s(-1) Mpc(-1) for our fiducial value of the sound horizon. These results from the anisotropic fitting are fully consistent with the analysis of the spherically averaged acoustic peak position presented in Anderson et al. Our distance measurements are a close match to the predictions of the standard cosmological model featuring a cosmological constant and zero spatial curvature.  
  Address [Anderson, Lauren] Univ Washington, Dept Astron, Seattle, WA 98195 USA, Email: djschlegel@lbl.gov  
  Corporate Author Thesis  
  Publisher Oxford Univ Press Place of Publication Editor  
  Language English Summary Language (up) Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0035-8711 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000333297700026 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1738  
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Author Koolen, B.B.; Vidal-Sicart, S.; Benlloch, J.M.; Olmos, R.A.V. doi  openurl
  Title Evaluating heterogeneity of primary tumor 18 F-FDG uptake in breast cancer with a dedicated breast PET ( MAMMI): a feasibility study based on correlation with PET/CT Type Journal Article
  Year 2014 Publication Nuclear Medicine Communications Abbreviated Journal Nucl. Med. Commun.  
  Volume 35 Issue 5 Pages 446-452  
  Keywords breast cancer; F-18-FDG; heterogeneity; MAMMI; PET  
  Abstract PurposeThe aim of the study was to evaluate the heterogeneity of primary tumor F-18-fluorodeoxyglucose (F-18-FDG) uptake in breast cancer patients using a dedicated breast PET.Patients and methodsA positron emission tomography/computed tomography (PET/CT) of the thorax was performed 60 min after administration of 180-240 MBq of F-18-FDG in patients with breast cancer. Subsequently, 110 min after injection, a scan was taken with a dedicated high-resolution breast PET [MAMmography with Molecular Imaging (MAMMI)]. Both procedures were performed with the patients in the prone position. Four-point scores were used to compare the intensity (0: none; 1: mild; 2: moderate; 3: high) and heterogeneity (0: none; 1: mild; 2: moderate; 3: high) of F-18-FDG uptake between PET/CT and MAMMI images.ResultsThirty-five patients in whom the primary tumor was visualized on both scans were included in this analysis. The mean primary tumor size was 35.1 mm (range 10-108 mm). The mean intensity score was similar on both devices (2.4 for PET/CT and 2.3 for MAMMI; P=0.439), but the mean heterogeneity score on MAMMI images was significantly higher (PET/CT 1.9 vs. MAMMI 2.3; P=0.005). MAMMI showed a higher heterogeneity score in 11 (31%) of 35 patients, especially in tumors with moderate or high intensity. Significantly higher heterogeneity scores on both PET/CT and MAMMI were seen in large tumors (P=0.005 and 0.014, respectively) and in tumors with high intensity scores (P=0.012 and P<0.001, respectively).ConclusionHeterogeneous tumor F-18-FDG uptake in breast cancer is frequently observed, particularly in large tumors with intense F-18-FDG uptake. It is more often seen on MAMMI PET than on conventional PET/CT. Although the observed heterogeneity should be proven histopathologically, this finding offers a rationale for F-18-FDG-guided biopsies.  
  Address [Koolen, Bas B.; Vidal-Sicart, Sergi; Olmos, Renato A. Valdes] Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Nucl Med, NL-1066 CX Amsterdam, Netherlands, Email: b.koolen@nki.nl  
  Corporate Author Thesis  
  Publisher Lippincott Williams & Wilkins Place of Publication Editor  
  Language English Summary Language (up) Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0143-3636 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000334103800002 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1763  
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