| Records |
| Author |
Solevi, P.; Muñoz, E.; Solaz, C.; Trovato, M.; Dendooven, P.; Gillam, J.E.; Lacasta, C.; Oliver, J.F.; Rafecas, M.; Torres-Espallardo, I.; Llosa, G. |
| Title |
Performance of MACACO Compton telescope for ion-beam therapy monitoring: first test with proton beams |
Type |
Journal Article |
| Year |
2016 |
Publication  |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
| Volume |
61 |
Issue |
14 |
Pages |
5149-5165 |
| Keywords |
ion-beam therapy; range verification; prompt gamma; Compton camera; GATE |
| Abstract |
In order to exploit the advantages of ion-beam therapy in a clinical setting, delivery verification techniques are necessary to detect deviations from the planned treatment. Efforts are currently oriented towards the development of devices for real-time range monitoring. Among the different detector concepts proposed, Compton cameras are employed to detect prompt gammas and represent a valid candidate for real-time range verification. We present the first on-beam test of MACACO, a Compton telescope (multi-layer Compton camera) based on lanthanum bromide crystals and silicon photo-multipliers. The Compton telescope was first characterized through measurements and Monte Carlo simulations. The detector linearity was measured employing Na-22 and Am-Be sources, obtaining about 10% deviation from linearity at 3.44 MeV. A spectral image reconstruction algorithm was tested on synthetic data. Point-like sources emitting gamma rays with energy between 2 and 7 MeV were reconstructed with 3-5 mm resolution. The two-layer Compton telescope was employed to measure radiation emitted from a beam of 150 MeV protons impinging on a cylindrical PMMA target. Bragg-peak shifts were achieved via adjustment of the PMMA target location and the resulting measurements used during image reconstruction. Reconstructed Bragg peak profiles proved sufficient to observe peak-location differences within 10 mm demonstrating the potential of the MACACO Compton Telescope as a monitoring device for ion-beam therapy. |
| Address |
[Solevi, Paola; Munoz, Enrique; Solaz, Carles; Trovato, Marco; Gillam, John E.; Lacasta, Carlos; Oliver, Josep F.; Rafecas, Magdalena; Torres-Espallardo, Irene; Llosa, Gabriela] IFIC CSIC UVEG, Inst Fis Corpuscular, Valencia, Spain, Email: paola.solevi@ovgu.de |
| Corporate Author |
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Thesis |
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| Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0031-9155 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000379555300007 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
2754 |
| Permanent link to this record |
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| Author |
Gimenez-Alventosa, V.; Gimenez, V.; Ballester, F.; Vijande, J.; Andreo, P. |
| Title |
Monte Carlo calculation of beam quality correction factors for PTW cylindrical ionization chambers in photon beams |
Type |
Journal Article |
| Year |
2020 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
| Volume |
65 |
Issue |
20 |
Pages |
205005 - 11pp |
| Keywords |
TRS 398; Monte Carlo; dosimetry; ionization chambers; MV photon beams |
| Abstract |
The beam quality correction factork(Q)for megavoltage photon beams has been calculated for eight PTW (Freiburg, Germany) ionization chambers (Farmer chambers PTW30010, PTW30011, PTW30012, and PTW30013, Semiflex 3D chambers PTW31021, PTW31010, and PTW31013, and the PinPoint 3D chamber PTW31016). Simulations performed on the widely used NE-2571 ionization chamber have been used to benchmark the results. The Monte Carlo code PENELOPE/penEasy was used to calculate the absorbed dose to a point in water and the absorbed dose to the active air volume of the chambers for photon beams in the range 4 to 24 MV. Of the nine ionization chambers analysed, only five are included in the current version of the International Code of Practice for dosimetry based on standards of absorbed dose to water (IAEA TRS 398). The values reported in this work agree with those in the literature within the uncertainty estimates and are to be included in the average values of the data obtained by different working groups for the forthcoming update of TRS 398. |
| Address |
[Gimenez-Alventosa, Vicent] Univ Politecn Valencia, CSIC, Ctr Mixto, Inst Instrumentac Imagen Mol I3M, Valencia, Spain, Email: javier.vijande@uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0031-9155 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000576070000001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
4556 |
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| Author |
Ros Garcia, A.; Barrio, J.; Etxebeste, A.; Garcia-Lopez, J.; Jimenez-Ramos, M.C.; Lacasta, C.; Muñoz, E.; Oliver, J.F.; Roser, J.; Llosa, G. |
| Title |
MACACO II test-beam with high energy photons |
Type |
Journal Article |
| Year |
2020 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
| Volume |
65 |
Issue |
24 |
Pages |
245027 - 12pp |
| Keywords |
Compton imaging; Compton camera; proton therapy; LaBr3; test-beam; image reconstruction |
| Abstract |
The IRIS group at IFIC Valencia is developing a three-layer Compton camera for treatment monitoring in proton therapy. The system is composed of three detector planes, each made of a LaBr3<i monolithic crystal coupled to a SiPM array. Having obtained successful results with the first prototype (MACACO) that demonstrated the feasibility of the proposed technology, a second prototype (MACACO II) with improved performance has been developed, and is the subject of this work. The new system has an enhanced detector energy resolution which translates into a higher spatial resolution of the telescope. The image reconstruction method has also been improved with an accurate model of the sensitivity matrix. The device has been tested with high energy photons at the National Accelerator Centre (CNA, Seville). The tests involved a proton beam of 18 MeV impinging on a graphite target, to produce 4.4 MeV photons. Data were taken at different system positions of the telescope with the first detector at 65 and 160 mm from the target, and at different beam intensities. The measurements allowed successful reconstruction of the photon emission distribution at two target positions separated by 5 mm in different telescope configurations. This result was obtained both with data recorded in the first and second telescope planes (two interaction events) and, for the first time in beam experiments, with data recorded in the three planes (three interaction events). |
| Address |
[Ros Garcia, A.; Barrio, J.; Etxebeste, A.; Lacasta, C.; Munoz, E.; Oliver, J. F.; Roser, J.; Llosa, G.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: arosgar@ific.uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0031-9155 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000600803000001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
4654 |
| Permanent link to this record |
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| Author |
Scandale, W. et al; Lari, L. |
| Title |
Optimization of the crystal assisted collimation of the SPS beam |
Type |
Journal Article |
| Year |
2013 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
| Volume |
726 |
Issue |
1-3 |
Pages |
182-186 |
| Keywords |
Accelerator; Beam collimation; Crystal; Channeling |
| Abstract |
The possibility for optimization of crystal assisted collimation has been studied at the CERN SPS for stored beams of protons and Pb ions with 270 GeV/c per unit charge. A bent silicon crystal used as a primary collimator deflects halo particles in the channeling regime, directing them into a tungsten absorber. In channeling conditions a strong reduction of off-momentum particle numbers produced in the crystal and absorber, which form collimation leakage, has been observed in the first high dispersion (HD) area downstream. The present study shows that the collimation leakage is minimal for some values of the absorber offset relative to the crystal. The optimal offset value is larger for Pb ions because of their considerably larger ionization losses in the crystal, which cause large increases of particle betatron oscillation amplitudes. The optimal absorber offset allows obtaining maximal efficiency of crystal-assisted collimation. |
| Address |
[Scandale, W.; Arduini, G.; Butcher, M.; Cerutti, F.; Gilardoni, S.; Lari, L.; Lechner, A.; Losito, R.; Masi, A.; Mereghetti, A.; Metral, E.; Mirarchi, D.; Montesano, S.; Redaelli, S.; Schoofs, P.; Smirnov, G.] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland, Email: alexander.taratin@cern.ch |
| Corporate Author |
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Thesis |
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| Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0370-2693 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000326482200020 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
1694 |
| Permanent link to this record |
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| Author |
Scandale, W. et al; Lari, L. |
| Title |
Observation of nuclear dechanneling length reduction for high energy protons in a short bent crystal |
Type |
Journal Article |
| Year |
2015 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
| Volume |
743 |
Issue |
|
Pages |
440-443 |
| Keywords |
Crystal; Channeling; Beam; Deflection |
| Abstract |
Deflection of 400 GeV/c protons by a short bent silicon crystal was studied at the CERN SPS. It was shown that the dechanneling probability increases while the dechanneling length decreases with an increase of incident angles of particles relative to the crystal planes. The observation of the dechanneling length reduction provides evidence of the particle population increase at the top levels of transverse energies in the potential well of the planar channels. (C) 2015 The Authors. Published by Elsevier B.V. |
| Address |
[Scandale, W.; Arduini, G.; Butcher, M.; Cerutti, F.; Garattini, M.; Gilardoni, S.; Lari, L.; Lechner, A.; Losito, R.; Masi, A.; Mereghetti, A.; Metral, E.; Mirarchi, D.; Montesano, S.; Redaelli, S.; Rossi, R.; Schoofs, P.; Smirnov, G.] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland, Email: alexander.taratin@cern.ch |
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Thesis |
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| Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0370-2693 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000352147500065 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
2201 |
| Permanent link to this record |
