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Author |
Valdes-Cortez, C.; Niatsetski, Y.; Perez-Calatayud, J.; Ballester, F.; Vijande, J. |
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Title |
A Monte Carlo study of the relative biological effectiveness in surface brachytherapy |
Type |
Journal Article |
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Year |
2022 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
49 |
Issue |
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Pages |
5576-5588 |
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Keywords |
Monte Carlo; relative biological effectiveness; surface HDR brachytherapy |
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Abstract |
Purpose This work aims to simulate clustered DNA damage from ionizing radiation and estimate the relative biological effectiveness (RBE) for radionuclide (rBT)- and electronic (eBT)-based surface brachytherapy through a hybrid Monte Carlo (MC) approach, using realistic models of the sources and applicators. Methods Damage from ionizing radiation has been studied using the Monte Carlo Damage Simulation algorithm using as input the primary electron fluence simulated using a state-of-the-art MC code, PENELOPE-2018. Two Ir-192 rBT applicators, Valencia and Leipzig, one Co-60 source with a Freiburg Flap applicator (reference source), and two eBT systems, Esteya and INTRABEAM, have been included in this study implementing full realizations of their geometries as disclosed by the manufacturer. The role played by filtration and tube kilovoltage has also been addressed. Results For rBT, an RBE value of about 1.01 has been found for the applicators and phantoms considered. In the case of eBT, RBE values for the Esteya system show an almost constant RBE value of about 1.06 for all depths and materials. For INTRABEAM, variations in the range of 1.12-1.06 are reported depending on phantom composition and depth. Modifications in the Esteya system, filtration, and tube kilovoltage give rise to variations in the same range. Conclusions Current clinical practice does not incorporate biological effects in surface brachytherapy. Therefore, the same absorbed dose is administered to the patients independently on the particularities of the rBT or eBT system considered. The almost constant RBE values reported for rBT support that assumption regardless of the details of the patient geometry, the presence of a flattening filter in the applicator design, or even significant modifications in the photon energy spectra above 300 keV. That is not the case for eBT, where a clear dependence on the eBT system and the characteristics of the patient geometry are reported. A complete study specific for each eBT system, including detailed applicator characteristics (size, shape, filtering, among others) and common anatomical locations, should be performed before adopting an existing RBE value. |
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Address |
[Valdes-Cortez, Christian] Hosp Reg Antofagasta, Nucl Med Dept, Antofagasta, Chile, Email: cvalcort@gmail.com |
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Wiley |
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English |
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ISSN |
0094-2405 |
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WOS:000811709400001 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5262 |
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Author |
Girard-Alcindor, V. et al; Domingo-Pardo, C. |
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Title |
New narrow resonances observed in the unbound nucleus F-15 |
Type |
Journal Article |
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Year |
2022 |
Publication |
Physical Review C |
Abbreviated Journal |
Phys. Rev. C |
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Volume |
105 |
Issue |
5 |
Pages |
L051301 - 7pp |
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Abstract |
The structure of the unbound F-15 nucleus is investigated using the inverse kinematics resonant scattering of a radioactive O-14 beam impinging on a CH2 target. The analysis of H-1(O-14, p) O-14 and H-1(O-14, 2p) N-13 reactions allowed the confirmation of the previously observed narrow 1/2(-) resonance, near the two-proton decay threshold, and the identification of two new narrow 5/2(-) and 3/2(-) resonances. The newly observed levels decay by 1p emission to the ground of O-14, and by sequential 2p emission to the ground state of N-13 via the 1(-) resonance of O-14. Gamow shell model (GSM) analysis of the experimental data suggests that the wave functions of the 5/2(-) and 3/2(-) resonances may be collectivized by the continuum coupling to nearby 2p- and 1p-decay channels. The observed excitation function H-1(O-14, p) O-14 and resonance spectrum in F-15 are well reproduced in the unified framework of the GSM. |
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Address |
[Girard-Alcindor, V.; Santos, F. de Oliveira; Ploszajczak, M.; Lemasson, A.; Clement, E.; Ramos, D.; Rejmund, M.; Ackermann, D.; Bastin, B.; Caceres, L.; De France, G.; Giraud, S.; Goupil, J.; Grevy, S.; Kamalou, O.; Kamenyero, A.; Leblond, S.; Lefevre, A.; Li, H.; Morfouace, P.; Stodel, C.; Thomas, J. C.] Grand Accelerateur Natl Ions Lourds GANIL, CEA, DRF CNRS, IN2P3, Bvd Henri Becquerel, F-14076 Caen, France, Email: stefan@ipno.in2p3.fr |
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Amer Physical Soc |
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English |
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2469-9985 |
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Notes ![sorted by Notes field, descending order (down)](img/sort_desc.gif) |
WOS:000811520800003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5268 |
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Author |
LHCb Collaboration (Aaij, R. et al); Jashal, B.K.; Martinez-Vidal, F.; Oyanguren, A.; Remon Alepuz, C.; Ruiz Vidal, J. |
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Title |
Angular Analysis of D0 -> x plus x-mu plus mu- and D0 -> K plus K-mu plus mu- Decays and Search for CP Violation |
Type |
Journal Article |
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Year |
2022 |
Publication |
Physical Review Letters |
Abbreviated Journal |
Phys. Rev. Lett. |
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Volume |
128 |
Issue |
22 |
Pages |
221801 - 11pp |
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Abstract |
The first full angular analysis and an updated measurement of the decay-rate CP asymmetry of the D0→π+π−μ+μ− and D0→K+K−μ+μ− decays are reported. The analysis uses proton-proton collision data collected with the LHCb detector at centre-of-mass energies of 7, 8 and 13 TeV. The data set corresponds to an integrated luminosity of 9 fb−1. The full set of CP-averaged angular observables and their CP asymmetries are measured as a function of the dimuon invariant mass. The results are consistent with expectations from the standard model and with CP symmetry. |
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Address |
[Leite, J. Baptista; Bediaga, I; Torres, M. Cruz; De Miranda, J. M.; dos Reis, A. C.; Falcao, L. N.; Gomes, A.; Massafferri, A.; Machado, D. Torres] Ctr Brasileiro Pesquisas Fis CBPF, Rio De Janeiro, Brazil |
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Amer Physical Soc |
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English |
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0031-9007 |
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Notes ![sorted by Notes field, descending order (down)](img/sort_desc.gif) |
WOS:000811308400003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5267 |
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Permanent link to this record |
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Author |
Renner, J. et al; Romo-Luque, C.; Carrion, J.V.; Diaz, J.; Martinez, A.; Querol, M.; Rodriguez-Ponce, J.; Teruel-Pardo, S. |
![goto web page (via DOI) doi](img/doi.gif)
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Title |
Monte Carlo characterization of PETALO, a full-body liquid xenon-based PET detector |
Type |
Journal Article |
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Year |
2022 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
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Volume |
17 |
Issue |
5 |
Pages |
P05044 - 17pp |
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Keywords |
Cryogenic detectors; Gamma camera; SPECT; PET PET; CT; coronary CT angiography (CTA); Liquid detectors |
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Abstract |
New detector approaches in Positron Emission Tomography imaging will play an important role in reducing costs, lowering administered radiation doses, and improving overall performance. PETALO employs liquid xenon as the active scintillating medium and UV-sensitive silicon photomultipliers for scintillation readout. The scintillation time in liquid xenon is fast enough to register time-of-flight information for each detected coincidence, and sufficient scintillation is produced with low enough fluctuations to obtain good energy resolution. The present simulation study examines a full-body-sized PETALO detector and evaluates its potential performance in PET image reconstruction. |
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Address |
[Romo-Luque, C.; Carrion, J. V.; Diaz, J.; Martinez, A.; Querol, M.; Rodriguez-Ponce, J.; Teruel-Pardo, S.] CSIC, Inst Fis Corpuscular IFIC, Calle Catedrat Jose Beltran 2, E-46980 Valencia, Spain, Email: paola.ferrario@dipc.org |
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IOP Publishing Ltd |
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English |
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1748-0221 |
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WOS:000811102400010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5264 |
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Permanent link to this record |
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Author |
NEXT Collaboration (Novella, P. et al); Carcel, S.; Carrion, J.V.; Diaz, J.; Martin-Albo, J.; Martinez, A.; Martinez-Vara, M.; Muñoz Vidal, J.; Palmeiro, B.; Querol, M.; Romo-Luque, C.; Sorel, M.; Uson, A.; Yahlali, N. |
![goto web page (via DOI) doi](img/doi.gif)
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Title |
Measurement of the Xe-136 two-neutrino double-beta-decay half-life via direct background subtraction in NEXT |
Type |
Journal Article |
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Year |
2022 |
Publication |
Physical Review C |
Abbreviated Journal |
Phys. Rev. C |
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Volume |
105 |
Issue |
5 |
Pages |
055501 - 8pp |
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Abstract |
We report a measurement of the half-life of the Xe-136 two-neutrino double-beta decay performed with a novel direct-background-subtraction technique. The analysis relies on the data collected with the NEXT-White detector operated with Xe-136-enriched and Xe-136-depleted xenon, as well as on the topology of double-electron tracks. With a fiducial mass of only 3.5 kg of Xe, a half-life of 2.34(-0.46)(+0.80) (stat)(-0.17)(+0.30) (sys) x 10(21) yr is derived from the background-subtracted energy spectrum. The presented technique demonstrates the feasibility of unique background-model-independent neutrinoless double-beta-decay searches. |
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Address |
[Novella, P.; Sorel, M.; Uson, A.; Carcel, S.; Carrion, J., V; Diaz, J.; Martin-Albo, J.; Martinez, A.; Martinez-Vara, M.; Vidal, J. Munoz; Palmeiro, B.; Querol, M.; Romo-Luque, C.; Yahlali, N.] CSIC, Inst Fis Corpuscular IFIC, Calle Catedrat Jose Beltran 2, E-46980 Paterna, Spain, Email: auson@ific.uv.es |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Language |
English |
Summary Language |
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ISSN |
2469-9985 |
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Notes ![sorted by Notes field, descending order (down)](img/sort_desc.gif) |
WOS:000810927800003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5263 |
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Permanent link to this record |