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Author |
Torres-Espallardo, I.; Diblen, F.; Rohling, H.; Solevi, P.; Gillam, J.; Watts, D.; Espana, S.; Vandenberghe, S.; Fiedler, F.; Rafecas, M. |
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Title |
Evaluation of resistive-plate-chamber-based TOF-PET applied to in-beam particle therapy monitoring |
Type |
Journal Article |
| |
Year |
2015 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
60 |
Issue |
9 |
Pages |
N187-N208 |
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Keywords  |
PET; in-beam; RPC; particle therapy; TOF; range deviation; partial-ring |
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Abstract |
Particle therapy is a highly conformal radiotherapy technique which reduces the dose deposited to the surrounding normal tissues. In order to fully exploit its advantages, treatment monitoring is necessary to minimize uncertainties related to the dose delivery. Up to now, the only clinically feasible technique for the monitoring of therapeutic irradiation with particle beams is Positron Emission Tomography (PET). In this work we have compared a Resistive Plate Chamber (RPC)-based PET scanner with a scintillation-crystal-based PET scanner for this application. In general, the main advantages of the RPC-PET system are its excellent timing resolution, low cost, and the possibility of building large area systems. We simulated a partial-ring scannerbeam monitoring, which has an intrinsically low positron yield compared to diagnostic PET. In addition, for in-beam PET there is a further data loss due to the partial ring configuration. In order to improve the performance of the RPC-based scanner, an improved version of the RPC detector (modifying the thickness of the gas and glass layers), providing a larger sensitivity, has been simulated and compared with an axially extended version of the crystal-based device. The improved version of the RPC shows better performance than the prototype, but the extended version of the crystal-based PET outperforms all other options. based on an RPC prototype under construction within the Fondazione per Adroterapia Oncologica (TERA). For comparison with the crystal-based PET scanner we have chosen the geometry of a commercially available PET scanner, the Philips Gemini TF. The coincidence time resolution used in the simulations takes into account the current achievable values as well as expected improvements of both technologies. Several scenarios (including patient data) have been simulated to evaluate the performance of different scanners. Initial results have shown that the low sensitivity of the RPC hampers its application to hadron |
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Address |
[Torres-Espallardo, I.; Solevi, P.; Gillam, J.; Rafecas, M.] UV, CSIC, Inst Fis Corpuscular IFIC, E-46071 Valencia, Spain, Email: irene.torres@uv.es |
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Publisher |
Iop Publishing Ltd |
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English |
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ISSN |
0031-9155 |
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Conference |
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Notes |
WOS:000354104700003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2227 |
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Author |
Brzezinski, K.; Oliver, J.F.; Gillam, J.; Rafecas, M. |
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Title |
Study of a high-resolution PET system using a Silicon detector probe |
Type |
Journal Article |
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Year |
2014 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
59 |
Issue |
20 |
Pages |
6117-6140 |
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Keywords |
PET; high-resolution imaging; Si detectors; PET insert |
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Abstract |
A high-resolution silicon detector probe, in coincidence with a conventional PET scanner, is expected to provide images of higher quality than those achievable using the scanner alone. Spatial resolution should improve due to the finer pixelization of the probe detector, while increased sensitivity in the probe vicinity is expected to decrease noise. A PET-probe prototype is being developed utilizing this principle. The system includes a probe consisting of ten layers of silicon detectors, each a 80 x 52 array of 1 x 1 x 1 mm(3) pixels, to be operated in coincidence with a modern clinical PET scanner. Detailed simulation studies of this system have been performed to assess the effect of the additional probe information on the quality of the reconstructed images. A grid of point sources was simulated to study the contribution of the probe to the system resolution at different locations over the field of view (FOV). A resolution phantom was used to demonstrate the effect on image resolution for two probe positions. A homogeneous source distribution with hot and cold regions was used to demonstrate that the localized improvement in resolution does not come at the expense of the overall quality of the image. Since the improvement is constrained to an area close to the probe, breast imaging is proposed as a potential application for the novel geometry. In this sense, a simplified breast phantom, adjacent to heart and torso compartments, was simulated and the effect of the probe on lesion detectability, through measurements of the local contrast recovery coefficient-to-noise ratio (CNR), was observed. The list-mode ML-EM algorithm was used for image reconstruction in all cases. As expected, the point spread function of the PET-probe system was found to be non-isotropic and vary with position, offering improvement in specific regions. Increase in resolution, of factors of up to 2, was observed in the region close to the probe. Images of the resolution phantom showed visible improvement in resolution when including the probe in the simulations. The image quality study demonstrated that contrast and spill-over ratio in other areas of the FOV were not sacrificed for this enhancement. The CNR study performed on the breast phantom indicates increased lesion detectability provided by the probe. |
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Address |
[Brzezinski, K.; Oliver, J. F.; Gillam, J.; Rafecas, M.] Univ Valencia, CSIC, Inst Fis Corpuscular, E-46980 Valencia, Spain, Email: brzezinski@ific.uv.es |
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Iop Publishing Ltd |
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English |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Conference |
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Notes |
WOS:000343092300011 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1963 |
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Author |
Beltrame, P. et al; Oliver, J.F.; Rafecas, M.; Solevi, P. |
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Title |
The AX-PET demonstrator-Design, construction and characterization |
Type |
Journal Article |
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Year |
2011 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
654 |
Issue |
1 |
Pages |
546-559 |
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Keywords |
PET; Axial geometry; Geiger-mode Avalanche Photo Diodes (G-APD); SiPM |
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Abstract |
Axial PET is a novel geometrical concept for Positron Emission Tomography (PET), based on layers of long scintillating crystals axially aligned with the bore axis. The axial coordinate is obtained from arrays of wavelength shifting (WLS) plastic strips placed orthogonally to the crystals. This article describes the design, construction and performance evaluation of a demonstrator set-up which consists of two identical detector modules, used in coincidence. Each module comprises 48 LYSO crystals of 100 mm length and 156 WLS strips. Crystals and strips are readout by Geiger-mode Avalanche Photo Diodes (G-APDs). The signals from the two modules are processed by fully analog front-end electronics and recorded in coincidence by a VME-based data acquisition system. Measurements with point-like (22)Na sources, with the modules used both individually and in coincidence mode, allowed for a complete performance evaluation up to the focal plane reconstruction of point sources. The results obtained are in good agreement with expectations and proved the set-up to be ready for the next evaluation phase with PET phantoms filled with radiotracers. |
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Address |
[Casella, C; Dissertori, G; Djambazov, L; Lustermann, W; Nessi-Tedaldi, F; Pauss, F; Renker, D; Schinzel, D] ETH, Inst Particle Phys, CH-8093 Zurich, Switzerland, Email: Chiara.Casella@cern.ch |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000295765100078 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
790 |
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| Permanent link to this record |
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Author |
Bolle, E.; Casella, C.; Chesi, E.; De Leo, R.; Dissertori, G.; Fanti, V.; Gillam, J.E.; Heller, M.; Joram, C.; Lustermann, W.; Nappi, E.; Oliver, J.F.; Pauss, F.; Rafecas, M.; Rudge, A.; Ruotsalainen, U.; Schinzel, D.; Schneider, T.; Seguinot, J.; Solevi, P.; Stapnes, S.; Tuna, U.; Weilhammer, P. |
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Title |
AX-PET: A novel PET concept with G-APD readout |
Type |
Journal Article |
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Year |
2012 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
695 |
Issue |
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Pages |
129-134 |
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Keywords |
PET; Axial geometry; Geiger-mode Avalanche Photo Diodes (G-APD); SiPM |
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Abstract |
The AX-PET collaboration has developed a novel concept for high resolution PET imaging to overcome some of the performance limitations of classical PET cameras, in particular the compromise between spatial resolution and sensitivity introduced by the parallax error. The detector consists of an arrangement of long LYSO scintillating crystals axially oriented around the field of view together with arrays of wave length shifter strips orthogonal to the crystals. This matrix allows a precise 3D measurement of the photon interaction point. This is valid both for photoelectric absorption at 511 key and for Compton scattering down to deposited energies of about 100 keV. Crystals and WLS strips are individually read out using Geiger-mode Avalanche Photo Diodes (G-APDs). The sensitivity of such a detector can be adjusted by changing the number of layers and the resolution is defined by the crystal and strip dimensions. Two AX-PET modules were built and fully characterized in dedicated test set-ups at CERN, with point-like Na-22 sources. Their performance in terms of energy (Renew approximate to 11.8% (FWMH) at 511 key) and spatial resolution was assessed (sigma(axial) approximate to 0.65 mm), both individually and for the two modules in coincidence. Test campaigns at ETH Zurich and at the company AAA allowed the tomographic reconstructions of more complex phantoms validating the 3D reconstruction algorithms. The concept of the AX-PET modules will be presented together with some characterization results. We describe a count rate model which allows to optimize the planing of the tomographic scans. |
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Address |
[Heller, M.; Joram, C.; Schneider, T.; Seguinot, J.] CERN, PH Dept, CH-1211 Geneva, Switzerland, Email: Matthieu.Heller@cern.ch |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000311469900026 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1236 |
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Author |
Ayala, C.; Cvetic, G.; Kogerler, R. |
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Title |
Lattice-motivated holomorphic nearly perturbative QCD |
Type |
Journal Article |
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Year |
2017 |
Publication |
Journal of Physics G |
Abbreviated Journal |
J. Phys. G |
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Volume |
44 |
Issue |
7 |
Pages |
075001 - 30pp |
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Keywords |
perturbative QCD; lattice QCD; QCD phenomenology; resummation |
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Abstract |
Newer lattice results indicate that, in the Landau gauge at low spacelike momenta, the gluon propagator and the ghost dressing function are finite non-zero. This leads to a definition of the QCD running coupling, in a specific scheme, that goes to zero at low spacelike momenta. We construct a running coupling which fulfills these conditions, and at the same time reproduces to a high precision the perturbative behavior at high momenta. The coupling is constructed in such a way that it reflects qualitatively correctly the holomorphic (analytic) behavior of spacelike observables in the complex plane of the squared momenta, as dictated by the general principles of quantum field theories. Further, we require the coupling to reproduce correctly the nonstrange semihadronic decay rate of tau lepton which is the best measured low-momentum QCD observable with small higher-twist effects. Subsequent application of the Borel sum rules to the V + A spectral functions of tau lepton decays, as measured by OPAL Collaboration, determines the values of the gluon condensate and of the V + A six-dimensional condensate, and reproduces the data to a significantly higher precision than the usual (MS) over bar running coupling. |
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Address |
[Ayala, Cesar] Univ Valencia, Dept Theoret Phys, E-46100 Valencia, Spain, Email: Gorazd.Cvetic@usm.cl |
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Corporate Author |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0954-3899 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000402509800001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3167 |
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Author |
Oset, E.; Chen, H.X.; Feijoo, A.; Geng, L.S.; Liang, W.H.; Li, D.M.; Lu, J.X.; Magas, V.K.; Nieves, J.; Ramos, A.; Roca, L.; Wang, E.; Xie, J.J. |
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Title |
Study of reactions disclosing hidden charm pentaquarks with or without strangeness |
Type |
Journal Article |
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Year |
2016 |
Publication |
Nuclear Physics A |
Abbreviated Journal |
Nucl. Phys. A |
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Volume |
954 |
Issue |
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Pages |
371-392 |
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Keywords |
Pentaquark reactions; Molecular states with hidden charm |
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Abstract |
We present results for five reactions, Lambda(b) -> J/psi K(-)p, Lambda(b) -> J/psi eta Lambda, Lambda(b) -> J/psi pi(-)p, Lambda(b) -> J/psi K-0 Lambda and Xi(-)(b) -> J/psi K-Lambda, where combining information from the meson baryon interaction, using the chiral unitary approach, and predictions made for molecular states of hidden charm, with or without strangeness, we can evaluate invariant mass distributions for the light meson baryon states, and for those of J/psi p or J/psi Lambda. We show that with the present available information, in all of these reactions one finds peaks where the pentaquark states show up. In the Lambda(b) -> J/psi K(-)p, and Lambda(b) -> J/psi pi(-)p reactions we show that the results obtained from our study are compatible with present experimental observations. |
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Address |
[Oset, Eulogio] Univ Valencia, Ctr Mixto, CSIC, Inst Invest Paterna,Dept Fis Teor, Aptdo 22085, E-46071 Valencia, Spain, Email: oset@ific.uv.es |
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Corporate Author |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0375-9474 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000381331200025 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2791 |
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Author |
Kowalska, M.; Naimi, S.; Agramunt, J.; Algora, A.; Beck, D.; Blank, B.; Blaum, K.; Bohm, C.; Borgmann, C.; Breitenfeldt, M.; Fraile, L.M.; George, S.; Herfurth, F.; Herlert, A.; Kreim, S.; Lunney, D.; Minaya-Ramirez, E.; Neidherr, D.; Rosenbusch, M.; Rubio, B.; Schweikhard, L.; Stanja, J.; Zuber, K. |
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Title |
Trap-assisted decay spectroscopy with ISOLTRAP |
Type |
Journal Article |
| |
Year |
2012 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
689 |
Issue |
|
Pages |
102-107 |
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Keywords |
Penning trap mass spectrometers; Trap-assisted decay spectroscopy; Studies at ISOL-type facilities |
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Abstract |
Penning traps are excellent high-precision mass spectrometers for radionuclides. The high-resolving power used for cleaning isobaric and even isomeric contaminants can be exploited to improve decay-spectroscopy studies by delivering purified samples. An apparatus allowing trap-assisted decay spectroscopy has been coupled to the ISOLTRAP mass spectrometer at ISOLDE/CERN. The results from studies with stable and radioactive ions show that the setup can be used to perform decay studies on purified short-lived nuclides and to assist mass measurements. |
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Address |
[Kowalska, M.; Herlert, A.] CERN, Dept Phys, CH-1211 Geneva 23, Switzerland, Email: kowalska@cern.ch |
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Corporate Author |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000307797500016 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1134 |
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Author |
Peinado, E.; Reig, M.; Srivastava, R.; Valle, J.W.F. |
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Title |
Dirac neutrinos from Peccei-Quinn symmetry: A fresh look at the axion |
Type |
Journal Article |
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Year |
2020 |
Publication |
Modern Physics Letters A |
Abbreviated Journal |
Mod. Phys. Lett. A |
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Volume |
35 |
Issue |
21 |
Pages |
2050176 - 9pp |
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Keywords |
Peccei-Quinn symmetry; axion; neutrinos |
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Abstract |
We show that a very simple solution to the strong CP problem naturally leads to Dirac neutrinos. Small effective neutrino masses emerge from a type-I Dirac seesaw mechanism. Neutrino mass limits probe the axion parameters in regions currently inaccessible to conventional searches. |
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Address |
[Peinado, Eduardo] Univ Nacl Autonoma Mexico, Inst Fis, AP 20-364, Ciudad De Mexico 01000, Mexico, Email: epeinado@fisica.unam.mx; |
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Corporate Author |
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Publisher |
World Scientific Publ Co Pte Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0217-7323 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000550796000006 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4467 |
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| Permanent link to this record |
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Author |
Dias, A.G.; Leite, J.; Valle, J.W.F.; Vaquera-Araujo, C.A. |
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Title |
Reloading the axion in a 3-3-1 setup |
Type |
Journal Article |
| |
Year |
2020 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
810 |
Issue |
|
Pages |
135829 - 12pp |
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Keywords |
Peccei-Quinn symmetry; Axion; Neutrinos |
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Abstract |
We generalize the idea of the axion to an extended electroweak gauge symmetry setup. We propose a minimal axion extension of the Singer-Valle-Schechter (SVS) theory, in which the standard model fits in SU(3)(L) circle times U(1)(X), the number of families results from anomaly cancellation, and the Peccei-Quinn (PQ) solution to the strong-CP problem is implemented. Neutrino masses arise from a type-I Dirac seesaw mechanism, suppressed by the ratio of SVS and PQ scales, suggesting the existence of new physics at a moderate SVS scale. Novel features include an enhanced axion coupling to photons when compared to the DFSZ axion, as well as flavor-changing axion couplings to quarks. |
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Address |
[Dias, Alex G.; Leite, Julio] Univ Fed ABC, Ctr Ciencias Nat & Humanas, BR-09210580 Santo Andre, SP, Brazil, Email: alex.dias@ufabc.edu.br; |
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Corporate Author |
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Thesis |
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Publisher |
Elsevier |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0370-2693 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000582969900048 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4586 |
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| Permanent link to this record |
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Author |
Rinaldi, M.; Scopetta, S.; Traini, M.; Vento, V. |
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Title |
Double parton scattering: A study of the effective cross section within a Light-Front quark model |
Type |
Journal Article |
| |
Year |
2016 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
752 |
Issue |
|
Pages |
40-45 |
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Keywords |
Partons; Multi parton interactions; Parton correlations |
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Abstract |
We present a calculation of the effective cross section sigma(eff), an important ingredient in the description of double parton scattering in proton-proton collisions. Our theoretical approach makes use of a Light-Front quark model as a framework to calculate the double parton distribution functions at low-resolution scale. QCD evolution is implemented to reach the experimental scale. The obtained values of sigma(eff) in the valence region are consistent with the present experimental scenario, in particular with the sets of data which include the same kinematical range. However the result of the complete calculation shows a dependence of sigma(eff) on x(i), a feature not easily seen in the available data, probably because of their low accuracy. Measurements of sigma(eff) in restricted x(i) regions are addressed to obtain indications on double parton correlations, a novel and interesting aspect of the three dimensional structure of the nucleon. |
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Address |
[Rinaldi, Matteo; Scopetta, Sergio] Univ Perugia, Dipartimento Fis & Geol, I-06123 Perugia, Italy, Email: sergio.scopetta@pg.infn.it |
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Corporate Author |
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Thesis |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0370-2693 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000368026000007 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2532 |
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