Abstract: The direct detection of gravitational waves (GWs) of frequencies above MHz has recently received considerable attention. In this work, we present a precise study of the reach of a cubic cavity resonator to GWs in the microwave range, using for the first time tools allowing to perform realistic simulations. Concretely, the boundary integral -resonant mode expansion (BI-RME) 3D method, which allows us to obtain not only the detected power but also the detected voltage (magnitude and phase), is used here. After analyzing three cubic cavities for different frequencies and working simultaneously with three different degenerate modes at each cavity, we conclude that the sensitivity of the experiment is strongly dependent on the polarization and incidence angle of the GW. The presented experiment can reach sensitivities up to 1 x 10 – 19 at 100 MHz, 2 x 10 – 20 at 1 GHz, and 6 x 10 – 19 at 10 GHz for optimal angles and polarizations, and where in all cases we assumed an integration time of Delta t 1 / 4 1 ms. These results provide a strong case for further developing the use of cavities to detect GWs. Moreover, the possibility of analyzing the detected voltage (magnitude and phase) opens a new interferometric detection scheme based on the combination of the detected signals from multiple cavities.

Abstract: We present a calculation for the masses of the first radially excited states of 40 mesons and diquarks made up of u , d , s , c , and b quarks, including states that contain one or both heavy quarks. To this end, we employ a combined analysis of the Bethe-Salpeter and Schwinger-Dyson equations within a self-consistent and symmetry-preserving vector-vector contact interaction. The same set of parameters describes ground and excited states of mesons and their diquark partners. The wave function of the first radial excitation contains a zero whose location is correlated with an additional parameter d F which is a function of dressed quark masses. Our results satisfy the equal spacing rules given by the Gell-Mann Okubo mass relations. Wherever possible, we make comparisons of our findings with known experimental observations as well as theoretical predictions of several other models and approaches including lattice quantum chromodynamics, finding a very good agreement. We report predictions for a multitude of radial excitations not yet observed in experiments.

Abstract: In the framework of the low -energy effective theory containing, in addition to the Standard -Model fields, heavy neutral leptons (HNLs), we compute the decay rates of neutral and charged kaons into HNLs. We consider both lepton -number -conserving and lepton -number -violating four-fermion operators, taking into account also the contribution of active -heavy neutrino mixing. Assuming that the produced HNLs are longlived, we perform simulations and calculate the sensitivities of future long -lived -particle (LLP) detectors at the high -luminosity LHC as well as the near detector of the Deep Underground Neutrino Experiment (DUNE -ND) to the considered scenario. When applicable, we also recast the existing bounds on the minimal mixing case obtained by NA62, T2K, and PS191. Our findings show that, while the future LHC LLP detectors can probe currently allowed parameter space only in certain benchmark scenarios, DUNE -ND should be sensitive to parameter space beyond the current bounds in almost all the benchmark scenarios, and, for some of the effective operators considered, it can even probe new -physics scales in excess of 3000 TeV.

Abstract: We present a search for magnetic monopoles and high-electric-charge objects using LHC Run 2 root s = 13TeV proton-proton collisions recorded by the ATLAS detector. A total integrated luminosity of 138 fb(-1) was collected by a specialized trigger. No highly ionizing particle candidate was observed. Considering the Drell-Yan and photon-fusion pair production mechanisms as benchmark models, cross-section upper limits are presented for spin-0 and spin-1/2 magnetic monopoles of magnetic charge 1g(D) and 2g(D) and for high-electric-charge objects of electric charge 20 <= vertical bar z vertical bar <= 100, for masses between 200 GeV and 4000 GeV. The search improves by approximately a factor of three the previous cross-section limits on the Drell-Yan production of magnetic monopoles and high-electric charge objects. Also, the first ATLAS limits on the photon-fusion pair production mechanism of magnetic monopoles and high-electric-charge objects are obtained.

Abstract: In small clinical studies, the application of transcranial photobiomodulation (PBM), which typically delivers low-intensity near-infrared (NIR) to treat the brain, has led to some remarkable results in the treatment of dementia and several neurodegenerative diseases. However, despite the extensive literature detailing the mechanisms of action underlying PBM outcomes, the specific mechanisms affecting neurodegenerative diseases are not entirely clear. While large clinical trials are warranted to validate these findings, evidence of the mechanisms can explain and thus provide credible support for PBM as a potential treatment for these diseases. Tubulin and its polymerized state of microtubules have been known to play important roles in the pathology of Alzheimer's and other neurodegenerative diseases. Thus, we investigated the effects of PBM on these cellular structures in the quest for insights into the underlying therapeutic mechanisms. In this study, we employed a Raman spectroscopic analysis of the amide I band of polymerized samples of tubulin exposed to pulsed low-intensity NIR radiation (810 nm, 10 Hz, 22.5 J/cm2 dose). Peaks in the Raman fingerprint region (300-1900 cm-1)-in particular, in the amide I band (1600-1700 cm-1)-were used to quantify the percentage of protein secondary structures. Under this band, hidden signals of C=O stretching, belonging to different structures, are superimposed, producing a complex signal as a result. An accurate decomposition of the amide I band is therefore required for the reliable analysis of the conformation of proteins, which we achieved through a straightforward method employing a Voigt profile. This approach was validated through secondary structure analyses of unexposed control samples, for which comparisons with other values available in the literature could be conducted. Subsequently, using this validated method, we present novel findings of statistically significant alterations in the secondary structures of polymerized NIR-exposed tubulin, characterized by a notable decrease in alpha-helix content and a concurrent increase in beta-sheets compared to the control samples. This PBM-induced alpha-helix to beta-sheet transition connects to reduced microtubule stability and the introduction of dynamism to allow for the remodeling and, consequently, refreshing of microtubule structures. This newly discovered mechanism could have implications for reducing the risks associated with brain aging, including neurodegenerative diseases like Alzheimer's disease, through the introduction of an intervention following this transition.