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Author |
Carrasco-Ribelles, L.A.; Pardo-Mas, J.R.; Tortajada, S.; Saez, C.; Valdivieso, B.; Garcia-Gomez, J.M. |
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Title |
Predicting morbidity by local similarities in multi-scale patient trajectories |
Type |
Journal Article |
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Year |
2021 |
Publication |
Journal of Biomedical Informatics |
Abbreviated Journal |
J. Biomed. Inform. |
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Volume |
120 |
Issue  |
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Pages |
103837 - 9pp |
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Keywords |
Patient trajectory; Risk prediction; Local alignment; Dynamic programming; Diabetes; Cardiovascular disease |
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Abstract |
Patient Trajectories (PTs) are a method of representing the temporal evolution of patients. They can include information from different sources and be used in socio-medical or clinical domains. PTs have generally been used to generate and study the most common trajectories in, for instance, the development of a disease. On the other hand, healthcare predictive models generally rely on static snapshots of patient information. Only a few works about prediction in healthcare have been found that use PTs, and therefore benefit from their temporal dimension. All of them, however, have used PTs created from single-source information. Therefore, the use of longitudinal multi-scale data to build PTs and use them to obtain predictions about health conditions is yet to be explored. Our hypothesis is that local similarities on small chunks of PTs can identify similar patients concerning their future morbidities. The objectives of this work are (1) to develop a methodology to identify local similarities between PTs before the occurrence of morbidities to predict these on new query individuals; and (2) to validate this methodology on risk prediction of cardiovascular diseases (CVD) occurrence in patients with diabetes. We have proposed a novel formal definition of PTs based on sequences of longitudinal multi-scale data. Moreover, a dynamic programming methodology to identify local alignments on PTs for predicting future morbidities is proposed. Both the proposed methodology for PT definition and the alignment algorithm are generic to be applied on any clinical domain. We validated this solution for predicting CVD in patients with diabetes and we achieved a precision of 0.33, a recall of 0.72 and a specificity of 0.38. Therefore, the proposed solution in the diabetes use case can result of utmost utility to secondary screening. |
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Address |
[Carrasco-Ribelles, Lucia A.; Pardo-Mas, Jose Ramon; Saez, Carlos; Garcia-Gomez, Juan M.] Univ Politecn Valencia, Biomed Data Sci Lab BDSLAB, Inst Tecnol Informat & Comunicac ITACA, Camino Vera S-N, Valencia 46022, Spain, Email: lucarri@etsii.upv.es; |
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Academic Press Inc Elsevier Science |
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English |
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ISSN |
1532-0464 |
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Conference |
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Notes |
WOS:000683527500003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
4934 |
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Author |
Wieduwilt, P.; Paschen, B.; Schreeck, H.; Schwenker, B.; Soltau, J.; Ahlburg, P.; Dingfelder, J.; Frey, A.; Gomis, P.; Lutticke, F.; Marinas, C. |
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Title |
Performance of production modules of the Belle II pixel detector in a high-energy particle beam |
Type |
Journal Article |
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Year |
2021 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
991 |
Issue |
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Pages |
164978 - 15pp |
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Keywords |
DEPFET; DESY testbeam; Pixel detector; Belle II; Vertex detector |
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Abstract |
The Belle II experiment at the Super B factory SuperKEKB, an asymmetric e(+) e(-) collider located in Tsukuba, Japan, is tailored to perform precision B physics measurements. The centre of mass energy of the collisions is equal to the rest mass of the gamma (4S) resonance of m(gamma(4S)) = 10.58 GeV. A high vertex resolution is essential for measuring the decay vertices of B mesons. Typical momenta of the decay products are ranging from a few tens of MeV to a few GeV and multiple scattering has a significant impact on the vertex resolution. The VerteX Detector (VXD) for Belle II is therefore designed to have as little material as possible inside the acceptance region. Especially the innermost two layers, populated by the PiXel Detector (PXD), have to be ultra-thin. The PXD is based on DEpleted P-channel Field Effect Transistors (DEPFETs) with a thickness of only 75 μm. Spatial resolution and hit efficiency of production detector modules were studied in beam tests performed at the DESY test beam facility. The spatial resolution was investigated as a function of the incidence angle and improvements due to charge sharing are demonstrated. The measured module performance is compatible with the requirements for Belle II. |
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Address |
[Paschen, B.; Ahlburg, P.; Dingfelder, J.; Luetticke, F.] Univ Bonn, Phys Inst, Nussallee 12, D-53115 Bonn, Germany, Email: philipp.wieduwilt@phys.uni-goettingen.de; |
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Elsevier |
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English |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000686054900010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4941 |
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Author |
Vijande, J.; Tedgren, A.C.; Ballester, F.; Baltas, D.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; De Werd, L.; Perez-Calatayud, J. |
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Title |
Source strength determination in iridium-192 and cobalt-60 brachytherapy: A European survey on the level of agreement between clinical measurements and manufacturer certificates |
Type |
Journal Article |
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Year |
2021 |
Publication |
Physics and Imaging in Radiation Oncology |
Abbreviated Journal |
Phys. Imag. Radiat. Oncol. |
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Volume |
19 |
Issue |
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Pages |
108-111 |
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Keywords |
RAKR; Calibration; HDR; PDR; Brachytherapy |
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Abstract |
Background and purpose: Brachytherapy treatment outcomes depend on the accuracy of the delivered dose distribution, which is proportional to the reference air-kerma rate (RAKR). Current societal recommendations require the medical physicist to compare the measured RAKR values to the manufacturer source calibration certificate. The purpose of this work was to report agreement observed in current clinical practice in the European Union. Materials and methods: A European survey was performed for high- and pulsed-dose-rate (HDR and PDR) highenergy sources (Ir-192 and Co-60), to quantify observed RAKR differences. Medical physicists at eighteen hospitals from eight European countries were contacted, providing 1,032 data points from 2001 to 2020. Results: Over the survey period, 77% of the Ir-192 measurements used a well chamber instead of the older Krieger phantom method. Mean differences with the manufacturer calibration certificate were 0.01% +/- 1.15% for Ir-192 and -0.1% +/- 1.3% for Co-60. Over 95% of RAKR measurements in the clinic were within 3% of the manufacturer calibration certificate. Conclusions: This study showed that the agreement level was generally better than that reflected in prior societal recommendations positing 5%. Future recommendations on high-energy HDR and PDR source calibrations in the clinic may consider tightened agreements levels. |
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Address |
[Vijande, Javier; Ballester, Facundo] Univ Valencia UV, Dept Fis Atom Mol & Nucl, Burjassot, Spain, Email: Javier.vijande@uv.es |
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Elsevier |
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English |
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Notes |
WOS:000694711800017 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4969 |
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Author |
Jay, G.; Arnault, P.; Debbasch, F. |
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Title |
Dirac quantum walks with conserved angular momentum |
Type |
Journal Article |
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Year |
2021 |
Publication |
Quantum Studies-Mathematics and Foundations |
Abbreviated Journal |
Quantum Stud. Math. Found. |
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Volume |
8 |
Issue |
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Pages |
419-430 |
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Keywords |
Quantum walks; Quantum simulation; Lattice field theory |
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Abstract |
A quantum walk (QW) simulating the flat (1+2)D Dirac equation on a spatial polar grid is constructed. Because fermions are represented by spinors, which do not constitute a representation of the rotation group SO(3), but rather of its double cover SU(2), the QW can only be defined globally on an extended spacetime where the polar angle extends from 0 to 4 pi. The coupling of the QW with arbitrary electromagnetic fields is also presented. Finally, the cylindrical relativistic Landau levels of the Dirac equation are computed explicitly and simulated by the QW. |
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Address |
[Jay, Gareth] Univ Western Australia, Phys Dept, Perth, WA 6009, Australia, Email: gareth.jay@uwa.edu.au; |
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Publisher |
Springer |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Edition |
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ISSN |
2196-5609 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000697709700001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4975 |
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Author |
Barrientos, L.; Borja-Lloret, M.; Etxebeste, A.; Muñoz, E.; Oliver, J.F.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G. |
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Title |
Performance evaluation of MACACO II Compton camera |
Type |
Journal Article |
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Year |
2021 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
1014 |
Issue |
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Pages |
165702 - 7pp |
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Keywords |
Compton camera; Hadron therapy; LaBr3; Silicon photomultipliers |
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Abstract |
The IRIS group at IFIC-Valencia has developed a second version of a Compton camera prototype for hadron therapy treatment monitoring, with the aim of improving the performance with respect to its predecessor. The system is composed of three Lanthanum (III) bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs). The detector energy resolution has been improved to 5.6% FWHM at 511 keV and an angular resolution of 8.0 degrees has been obtained. Images of a Na-22 point-like source have been reconstructed selecting two and three interaction events. Moreover, the experimental data have been reproduced with Monte Carlo simulations using a Compton camera module (CCMod) in GATE v8.2 obtaining a good correlation. |
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Address |
[Barrientos, L.; Borja-Lloret, M.; Munoz, E.; Oliver, J. F.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G.] Univ Valencia, Inst Fis Corpuscular, CSIC, Valencia, Spain, Email: lbarrien@ific.uv.es |
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Corporate Author |
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Thesis |
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Publisher |
Elsevier |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000701263400010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4976 |
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| Permanent link to this record |
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Author |
Beltran Jimenez, J.; Delhom, A.; Olmo, G.J.; Orazi, E. |
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Title |
Born-Infeld gravity: Constraints from light-by-light scattering and an effective field theory perspective |
Type |
Journal Article |
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Year |
2021 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
820 |
Issue |
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Pages |
136479 - 6pp |
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Keywords |
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Abstract |
By using a novel technique that establishes a correspondence between general relativity and metric-affine theories based on the Ricci tensor, we are able to set stringent constraints on the free parameter of Born-Infeld gravity from the ones recently obtained for Born-Infeld electrodynamics by using light-by light scattering data from ATLAS. We also discuss how these gravity theories plus matter fit within an effective field theory framework. |
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Address |
[Beltran Jimenez, Jose] Univ Salamanca, Dept Fis Fundamental, E-37008 Salamanca, Spain, Email: jose.beltran@usal.es; |
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Thesis |
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Publisher |
Elsevier |
Place of Publication |
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Editor |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0370-2693 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000701707400005 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4978 |
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Author |
ATLAS Collaboration (Aad, G. et al); Aparisi Pozo, J.A.; Bailey, A.J.; Cabrera Urban, S.; Cardillo, F.; Castillo, F.L.; Castillo Gimenez, V.; Costa, M.J.; Escobar, C.; Estrada Pastor, O.; Ferrer, A.; Fiorini, L.; Fullana Torregrosa, E.; Fuster, J.; Garcia, C.; Garcia Navarro, J.E.; Gonzalez de la Hoz, S.; Gonzalvo Rodriguez, G.R.; Guerrero Rojas, J.G.R.; Higon-Rodriguez, E.; Lacasta, C.; Lozano Bahilo, J.J.; Mamuzic, J.; Marti-Garcia, S.; Martinez Agullo, P.; Mitsou, V.A.; Moreno Llacer, M.; Poveda, J.; Prades Ibañez, A.; Rodriguez Bosca, S.; Ruiz-Martinez, A.; Sabatini, P.; Salt, J.; Santra, A.; Sayago Galvan, I.; Soldevila, U.; Sanchez, J.; Torro Pastor, E.; Valero, A.; Valls Ferrer, J.A.; Villaplana Perez, M.; Vos, M. |
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Title |
Search for resonances decaying into photon pairs in 139 fb(-1) of pp collisions at root s=13 TeV with the ATLAS detector |
Type |
Journal Article |
| |
Year |
2021 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
822 |
Issue |
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Pages |
136651 - 19pp |
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Keywords |
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Abstract |
Searches for new resonances in the diphoton final state, with spin 0 as predicted by theories with an extended Higgs sector and with spin 2 using a warped extra-dimension benchmark model, are presented using 139 fb(-1) of root s = 13 TeV pp collision data collected by the ATLAS experiment at the LHC. No significant deviation from the Standard Model is observed and upper limits are placed on the production cross-section times branching ratio to two photons as a function of the resonance mass. |
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Address |
[Duvnjak, D.; Jackson, P.; Kong, A. X. Y.; Oliver, J. L.; Ruggeri, T. A.; Sharma, A. S.; White, M. J.] Univ Adelaide, Dept Phys, Adelaide, SA, Australia |
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Publisher |
Elsevier |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0370-2693 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000703669100040 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4982 |
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| Permanent link to this record |
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Author |
Gonzalez-Iglesias, D.; Aksoy, A.; Esperante, D.; Gimeno, B.; Latina, A.; Boronat, M.; Blanch, C.; Fuster-Martinez, N.; Martinez-Reviriego, P.; Martin-Luna, P.; Fuster, J. |
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Title |
X-band RF photoinjector design for the CompactLight project |
Type |
Journal Article |
| |
Year |
2021 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
1014 |
Issue |
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Pages |
165709 - 10pp |
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Keywords |
Photoinjector; X-band; Electron sources; Free electron laser; Beam generation |
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Abstract |
RF photoinjectors have been under development for several decades to provide the high-brightness electron beams required for X-ray Free Electron Lasers. This paper proposes a photoinjector design that meets the Horizon 2020 CompactLight design study requirements. It consists of a 5.6-cell, X-band (12 GHz) RF gun, an emittance-compensating solenoid and two X-band traveling-wave structures that accelerate the beam out of the space-charge-dominated regime. The RF gun is intended to operate with a cathode gradient of 200 MV/m, and the TW structures at a gradient of 65 MV/m. The shape of the gun cavity cells was optimized to reduce the peak electric surface field. An assessment of the gun RF breakdown likelihood is presented as is a multipacting analysis for the gun coaxial coupler. RF pulse heating on the gun inner surfaces is also evaluated and beam dynamics simulations of the 100 MeV photoinjector are summarized. |
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Address |
[Gonzalez-Iglesias, D.; Esperante, D.; Gimeno, B.; Boronat, M.; Blanch, C.; Fuster-Martinez, N.; Martinez-Reviriego, P.; Martin-Luna, P.; Fuster, J.] Univ Valencia Consejo Super Invest Cient, Inst Fis Corpuscular IFIC, Calle Catedrat Jose Beltran 2, Valencia 46980, Spain, Email: daniel.gonzalez-iglesias@uv.es |
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Publisher |
Elsevier |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000704382900005 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4983 |
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Author |
Vagnozzi, S.; Di Valentino, E.; Gariazzo, S.; Melchiorri, A.; Mena, O.; Silk, J. |
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Title |
The galaxy power spectrum take on spatial curvature and cosmic concordance |
Type |
Journal Article |
| |
Year |
2021 |
Publication |
Physics of the Dark Universe |
Abbreviated Journal |
Phys. Dark Universe |
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Volume |
33 |
Issue |
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Pages |
100851 - 17pp |
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Keywords |
Cosmological parameters; Spatial curvature; Cosmological tensions |
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Abstract |
The concordance of the ACDM cosmological model in light of current observations has been the subject of an intense debate in recent months. The 2018 Planck Cosmic Microwave Background (CMB) temperature anisotropy power spectrum measurements appear at face value to favour a spatially closed Universe with curvature parameter Omega(K) < 0. This preference disappears if Baryon Acoustic Oscillation (BAO) measurements are combined with Planck data to break the geometrical degeneracy, although the reliability of this combination has been questioned due to the strong tension present between the two datasets when assuming a curved Universe. Here, we approach this issue from yet another point of view, using measurements of the full-shape (FS) galaxy power spectrum, P(k), from the Baryon Oscillation Spectroscopic Survey DR12 CMASS sample. By combining Planck data with FS measurements, we break the geometrical degeneracy and find Omega(K) = 0.0023 +/- 0.0028. This constrains the Universe to be spatially flat to sub-percent precision, in excellent agreement with results obtained using BAO measurements. However, as with BAO, the overall increase in the best-fit chi(2) suggests a similar level of tension between Planck and P(k) under the assumption of a curved Universe. While the debate on spatial curvature and the concordance between cosmological datasets remains open, our results provide new perspectives on the issue, highlighting the crucial role of FS measurements in the era of precision cosmology. |
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Address |
[Vagnozzi, Sunny] Univ Cambridge, Kavli Inst Cosmol, Cambridge CB3 0HA, England, Email: sunny.vagnozzi@ast.cam.ac.uk; |
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Publisher |
Elsevier |
Place of Publication |
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Editor |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000704383100022 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4984 |
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Author |
Alvarez-Ruso, L.; Saul-Sala, E. |
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Title |
Neutrino interactions with matter and the MiniBooNE anomaly |
Type |
Journal Article |
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Year |
2021 |
Publication |
European Physical Journal-Special Topics |
Abbreviated Journal |
Eur. Phys. J.-Spec. Top. |
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Volume |
230 |
Issue |
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Pages |
4373-4389 |
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Keywords |
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Abstract |
The excess of electron-like events measured by MiniBooNE challenges our understanding of neutrinos and their interactions. We review the status of this open problem and ongoing efforts to resolve it. After introducing the experiment and its results, we consider the main experimental backgrounds and the related physics of neutrino interactions with matter, such as quasielastic-like scattering and weak pion production on nucleons and nuclei. Special attention is paid to single photon emission in neutral current interactions and, in particular, its coherent channel. The difficulties to reconcile the MiniBooNE anomaly with global oscillation analysis is then highlighted. We finally outline some of the proposed solutions of the puzzle involving unconventional neutrino-interaction mechanisms. |
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Address |
[Alvarez-Ruso, Luis] CSIC, Inst Fis Corpuscular IFIC, Valencia 46980, Spain, Email: Luis.Alvarez@ific.uv.es |
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Publisher |
Springer Heidelberg |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
|
Abbreviated Series Title |
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|
| |
Series Volume |
|
Series Issue |
|
Edition |
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| |
ISSN |
1951-6355 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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| |
Notes |
WOS:000709649400001 |
Approved |
no |
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| |
Is ISI |
yes |
International Collaboration |
no |
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| |
Call Number |
IFIC @ pastor @ |
Serial |
5007 |
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