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Author |
Peris, J.B.; Davis, P.; Cuevas, J.M.; Nebot, M.; Sanjuan, R. |
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Title |
Distribution of Fitness Effects Caused by Single-Nucleotide Substitutions in Bacteriophage f1 |
Type |
Journal Article |
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Year |
2010 |
Publication |
Genetics |
Abbreviated Journal |
Genetics |
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Volume |
185 |
Issue  |
2 |
Pages |
603-U308 |
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Keywords |
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Abstract |
Empirical knowledge of the fitness effects of mutations is important for understanding many evolutionary processes, yet this knowledge is often hampered by several sources of measurement error and bias. Most of these problems can be solved using site-directed mutagenesis to engineer single mutations, an approach particularly suited for viruses due to their small genomes. Here, we used this technique to measure the fitness effect of 100 single-nucleotide substitutions in the bacteriophage f1, a filamentous single-strand DNA virus. We found that approximately one-fifth of all mutations are lethal. Viable ones reduced fitness by 11% on average and were accurately described by a log-normal distribution. More than 90% of synonymous substitutions were selectively neutral, while those affecting intergenic regions reduced fitness by 14% on average. Mutations leading to amino acid substitutions had an overall mean deleterious effect of 37%, which increased to 45% for those changing the amino acid polarity. Interestingly, mutations affecting early steps of the infection cycle tended to be more deleterious than those affecting late steps. Finally, we observed at least two beneficial mutations. Our results confirm that high mutational sensitivity is a general property of viruses with small genomes, including RNA and single-strand DNA viruses infecting animals, plants, and bacteria. |
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Address |
[Peris, Joan B.; Davis, Paulina; Cuevas, Jose M.; Sanjuan, Rafael] Univ Valencia, Inst Cavanilles Biodiversitat & Biol Evolut, Valencia 46980, Spain, Email: rafael.sanjuan@uv.es |
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Genetics Soc Am |
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English |
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0016-6731 |
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ISI:000281905200017 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ elepoucu @ |
Serial |
383 |
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Author |
Noguera, S.; Vento, V. |
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Title |
The pion transition form factor and the pion distribution amplitude |
Type |
Journal Article |
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Year |
2010 |
Publication |
European Physical Journal A |
Abbreviated Journal |
Eur. Phys. J. A |
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Volume |
46 |
Issue |
2 |
Pages |
197-205 |
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Abstract |
Recent BaBar data on the pion transition form factor, whose Q(2)-dependence is much steeper then predicted by asymptotic Quantum Chromodynamics (QCD), have caused a renewed interest in its theoretical description. We present here a formalism based on a model-independent description for low photon virtuality and a high photon virtuality description based on QCD, which match at a scale Q(0). The high photon virtuality description incorporates a flat pion distribution amplitude, phi(x) = 1, at the matching scale Q(0) and QCD evolution from Q(0) to Q > Q(0). The flat pion distribution is connected, through soft pion theorems and chiral symmetry, to the pion valence parton distribution at the same low scale Q(0). The procedure leads to a good description of the data, and by incorporating additional twist-three effects, to an excellent description of the data. |
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Address |
[Noguera, S.] Univ Valencia, Dept Fis Teor, CSIC, E-46100 Valencia, Spain, Email: Santiago.Noguera@uv.es |
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Springer |
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English |
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1434-6001 |
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Notes |
ISI:000284869600005 |
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no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ elepoucu @ |
Serial |
312 |
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Author |
Kaskulov, M.; Hernandez, E.; Oset, E. |
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Title |
On the background in the gamma p -> omega(pi(0)gamma)p reaction and mixed event simulation |
Type |
Journal Article |
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Year |
2010 |
Publication |
European Physical Journal A |
Abbreviated Journal |
Eur. Phys. J. A |
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Volume |
46 |
Issue |
2 |
Pages |
223-230 |
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Abstract |
In this paper we evaluate sources of background of the gamma p -> omega p reaction, with the omega detected through its pi(0)gamma decay channel, to compare with the experiment carried out at ELSA. We find background from gamma p -> pi(0)pi(0)p followed by decay of a pi(0) into two gamma, recombining one pi(0) and one gamma, and from the gamma p -> pi(0)eta p reaction with subsequent decay of the eta into two photons. This background accounts for the data at pi(0)gamma invariant masses beyond 700 MeV, but strength is missing at lower invariant masses which was attributed to photon misidentification events, which we simulate to get a good reproduction of the experimental background. Once this is done, we perform an event mixing simulation to reproduce the calculated background and we find that the method provides a good description of the background. A closer look reveals this is accidental. We show that the mixed event generated background in the region of the omega mass and beyond is completely tied to the events at low pi(0)gamma invariant masses where the d sigma/dM(pi 0 gamma) distribution is much larger. This has as a consequence that the mixed event method produces the same background at high invariant masses independently of the actual background in that region, as a consequence of which, the method is unsuited to give the background at energies around the peak of the omega and beyond. |
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Address |
[Kaskulov, M.] Univ Giessen, Inst Theoret Phys, D-35392 Giessen, Germany, Email: murat.kaskulov@theo.physik.uni-giessen.de |
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Springer |
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English |
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Series Editor |
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Series Volume |
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Series Issue |
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ISSN |
1434-6001 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000284869600008 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
313 |
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Author |
Doring, M.; Oset, E.; Meissner, U.G. |
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Title |
Evaluation of the polarization observables I-S and I-C in the reaction gamma p -> pi(0)eta p |
Type |
Journal Article |
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Year |
2010 |
Publication |
European Physical Journal A |
Abbreviated Journal |
Eur. Phys. J. A |
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Volume |
46 |
Issue |
2 |
Pages |
315-323 |
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Keywords |
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Abstract |
We evaluate the polarization observables I-S and I-C for the reaction gamma p -> pi(0)eta p, using a chiral unitary framework developed earlier. The I-S and I-C observables have been recently measured for the first time by the CBELSA/TAPS Collaboration. The theoretical predictions of I-S and I-C, given for altogether 18 angle-dependent functions, are in good agreement with the measurements. Also, the asymmetry d Sigma/dcos theta evaluated here agrees with the data. We show the importance of the Delta(1700) D-33-resonance and its S-wave decay into eta Delta(1232). The result can be considered as a further confirmation of the dynamical nature of this resonance. At the highest energies, deviations of the predictions from the data start to become noticeable, which leaves room for additional processes and resonances such as a Delta(1940) D-33. We also point out how to further improve the calculation. |
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Address |
[Doering, M.; Meissner, U. -G.] Forschungszentrum Julich, Inst Kernphys, D-52425 Julich, Germany, Email: m.doering@fz-juelich.de |
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Springer |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6001 |
ISBN |
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Expedition |
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Conference |
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Notes |
ISI:000284869600016 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
314 |
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Author |
HADES Collaboration (Agakishiev, G. et al); Diaz, J.; Gil, A. |
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Title |
Origin of the low-mass electron pair excess in light nucleus-nucleus collisions |
Type |
Journal Article |
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Year |
2010 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
690 |
Issue |
2 |
Pages |
118-122 |
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Keywords |
Virtual bremsstrahlung; Dileptons; Nucleon-nucleon collisions |
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Abstract |
We report measurements of electron pair production in elementary p + p and d + p reactions at 1.25 GeV/mu with the HADES spectrometer. For the first time, the electron pairs were reconstructed for n + p reactions by detecting the proton spectator from the deuteron breakup. We find that the yield of electron pairs with invariant mass Me+e- > 0.15 GeV/c(2) is about an order of magnitude larger in n + p reactions as compared to p + p. A comparison to model calculations demonstrates that the production mechanism is not sufficiently described yet. The electron pair spectra measured in C + C reactions are compatible with a superposition of elementary n + p and p + p collisions, leaving little room for additional electron pair sources in such light collision systems. |
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Address |
[Froehlich, I.; Galatyuk, T.; Goebel, K.; Lorenz, M.; Markert, J.; Michel, J.; Muentz, C.; Pachmayer, Y. C.; Stroebele, H.; Stroth, J.; Sturm, C.; Tarantola, A.; Teilab, K.] Goethe Univ Frankfurt, Inst Kernphys, D-60438 Frankfurt, Germany, Email: t.galatyuk@gsi.de |
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Publisher |
Elsevier Science Bv |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Edition |
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ISSN |
0370-2693 |
ISBN |
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Conference |
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Notes |
ISI:000279513800003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
413 |
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Author |
Deo, A.Y.; Podolyak, Z.; Walker, P.M.; Algora, A.; Rubio, B.; Agramunt, J.; Fraile, L.M.; Al-Dahan, N.; Alkhomashi, N.; Briz, J.A.; Estevez, E.; Farrelly, G.; Gelletly, W.; Herlert, A.; Koster, U.; Maira, A.; Singla, S. |
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Title |
Structures of Po-201 and Rn-205 from EC/beta(+)-decay studies |
Type |
Journal Article |
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Year |
2010 |
Publication |
Physical Review C |
Abbreviated Journal |
Phys. Rev. C |
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Volume |
81 |
Issue |
2 |
Pages |
024322 - 8pp |
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Keywords |
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Abstract |
Several low-lying excited states in Rn-205(86)119 and Po-201(84)117 were identified for the first time following EC/beta(+) decay of Fr-205 and At-201, respectively, using gamma-ray and conversion electron spectroscopy at the CERN isotope separator on-line (ISOLDE) facility. The EC/beta(+) branch from Fr-205 was measured to be 1.5(2)%. The excited states of the daughter nuclei are understood in terms of the odd nucleon coupling to the neighboring even-even core. The neutron single-particle energies of the p(3/2) orbital relative to the f(5/2) ground state in Rn-205, and the f(5/2) orbital relative to the p(3/2) ground state in Po-201, were determined to be 31.4(2) and 5.7(3) keV, respectively. We tentatively identify a 13/2(+) isomeric level at 657.1(5) keV in Rn-205. The systematic behavior of the 13/2(+) and 3/2(-) levels is also discussed. |
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Address |
[Deo, A. Y.; Podolyak, Zs.; Walker, P. M.; Al-Dahan, N.; Alkhomashi, N.; Farrelly, G.; Gelletly, W.] Univ Surrey, Dept Phys, Guildford GU2 7XH, Surrey, England, Email: A.Deo@surrey.ac.uk |
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Publisher |
Amer Physical Soc |
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Language |
English |
Summary Language |
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Abbreviated Series Title |
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ISSN |
0556-2813 |
ISBN |
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Conference |
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Notes |
ISI:000278341300001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
431 |
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Author |
Magas, V.K.; Yamagata-Sekihara, J.; Hirenzaki, S.; Oset, E.; Ramos, A. |
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Title |
Proton emission off nuclei induced by kaons in flight |
Type |
Journal Article |
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Year |
2010 |
Publication |
Physical Review C |
Abbreviated Journal |
Phys. Rev. C |
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Volume |
81 |
Issue |
2 |
Pages |
024609 - 10pp |
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Keywords |
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Abstract |
We study the (K-, p) reaction on nuclei with a 1 GeV/c momentum kaon beam, paying special attention to the region of emitted protons having kinetic energy above 600 MeV, which was used to claim a deeply attractive kaon nucleus optical potential. Our model describes the nuclear reaction in the framework of a local density approach and the calculations are performed following two different procedures: one is based on a many-body method using the Lindhard function and the other is based on a Monte Carlo simulation. The simulation method offers flexibility to account for processes other than kaon quasielastic scattering, such as K- absorption by one and two nucleons, producing hyperons, and allows consideration of final-state interactions of the K-, the p, and all other primary and secondary particles on their way out of the nucleus, as well as the weak decay of the produced hyperons into pi N. We find a limited sensitivity of the cross section to the strength of the kaon optical potential. We also show a serious drawback in the experimental setup-the requirement for having, together with the energetic proton, at least one charged particle detected in the decay counter surrounding the target-as we find that the shape of the original cross section is appreciably distorted, to the point of invalidating the claims made in the experimental paper on the strength of the kaon nucleus optical. |
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Address |
[Magas, V. K.; Ramos, A.] Univ Barcelona, Dept Estructura & Constituents Mat, E-08028 Barcelona, Spain, Email: vladimir@ecm.ub.es |
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Amer Physical Soc |
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English |
Summary Language |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0556-2813 |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000278341300014 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
432 |
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Author |
Geng, L.S.; Guo, F.K.; Hanhart, C.; Molina, R.; Oset, E.; Zou, B.S. |
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Title |
Study of the f(2)(1270) , f(2)'(1525) , f(0)(1370) and f(0)(1710) in the J/psi radiative decays |
Type |
Journal Article |
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Year |
2010 |
Publication |
European Physical Journal A |
Abbreviated Journal |
Eur. Phys. J. A |
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Volume |
44 |
Issue |
2 |
Pages |
305-311 |
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Keywords |
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Abstract |
In this paper we present an approach to study the radiative decay modes of the J/psi into a photon and one of the tensor mesons f (2)(1270) , f' (2)(1525) , as well as the scalar ones f (0)(1370) and f (0)(1710) . Especially, we compare predictions that emerge from a scheme where the states appear dynamically in the solution of vector meson-vector meson scattering amplitudes to those from a (admittedly naive) quark model. We provide evidence that it might be possible to distinguish amongst the two scenarios, once improved data are available. |
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Address |
[Geng, L. S.; Molina, R.; Oset, E.] Univ Valencia, Ctr Mixto, CSIC, Dept Fis Teor,Inst Invest Paterna, Valencia 46071, Spain, Email: lsgeng@ific.uv.es |
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Publisher |
Springer |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6001 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000277182900014 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
466 |
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Author |
Ellis, J.; Hodgkinson, R.N.; Lee, J.S.; Pilaftsis, A. |
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Title |
Flavour geometry and effective Yukawa couplings in the MSSM |
Type |
Journal Article |
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Year |
2010 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
02 |
Issue |
2 |
Pages |
016 - 35pp |
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Keywords |
Supersymmetric Standard Model; B-Physics |
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Abstract |
We present a new geometric approach to the flavour decomposition of an arbitrary soft supersymmetry-breaking sector in the MSSM. Our approach is based on the geometry that results from the quark and lepton Yukawa couplings, and enables us to derive the necessary and sufficient conditions for a linearly-independent basis of matrices related to the completeness of the internal [SU(3) circle times U(1)](5) flavour space. In a second step, we calculate the effective Yukawa couplings that are enhanced at large values of tan beta for general soft supersymmetry-breaking mass parameters. We highlight the contributions due to non-universal terms in the flavour decompositions of the sfermion mass matrices. We present numerical examples illustrating how such terms are induced by renormalization-group evolution starting from universal input boundary conditions, and demonstrate their importance for the flavour-violating effective Yukawa couplings of quarks. |
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Address |
[Ellis, John] CERN, Div Theory, CH-1211 Geneva 23, Switzerland, Email: John.Ellis@cern.ch |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1126-6708 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000275223100016 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
482 |
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Author |
Ferrario, P.; Rodrigo, G. |
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Title |
Heavy colored resonances in t(t)over-bar + jet at the LHC |
Type |
Journal Article |
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Year |
2010 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
02 |
Issue |
2 |
Pages |
051 - 13pp |
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Keywords |
QCD Phenomenology |
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Abstract |
The LHC is the perfect environment for the study of new physics in the top quark sector. We study the possibility of detecting signals of heavy color-octet vector resonances, through the charge asymmetry, in t (t) over bar + jet events. Besides contributions with the t (t) over bar pair in a color-singlet state, the asymmetry gets also contributions which are proportional to the color factor f(abc)(2). This process is particularly interesting for extra-dimensional models, where the inclusive charge asymmetry generated by Kaluza-Klein excitations of the gluon vanishes at the tree level. We find that the statistical significance for the measurement of such an asymmetry is sizable for different values of the coupling constants and already at low energies. |
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Address |
[Ferrario, Paola; Rodrigo, German] UVEG, Consejo Super Invest Cient, Inst Fis Corpuscular, E-46071 Valencia, Spain, Email: paola.ferrario@ific.uv.es |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1126-6708 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000275223100051 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ elepoucu @ |
Serial |
483 |
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| Permanent link to this record |
