Vijande, J., Carmona, V., Lliso, F., Ballester, F., & Perez-Calatayud, J. (2024). An efficient component of the redundancy calibration program to ensure equipment stability by assaying HDR Ir-192 sources at the time of replacement. J. Appl. Clin. Med. Phys, 25(12), e14509–5pp.
Abstract: BackgroundBrachytherapy (BT) treatments involving temporary high-dose rate (HDR) sources are extensively employed in clinical practice. Ensuring the consistency of all measurement equipment at the hospital level is crucial, requiring a robust redundancy and consistency program. This enables the institution to verify the stability of the dosimetry system over time.PurposeTo describe, justify, and analyze a component of the redundancy program of the calibration protocols followed by the Radiotherapy Department of the Hospital Universitari i Polit & egrave;cnic La Fe (Val & egrave;ncia, Spain) during the last 10 years for the case of HDR BT as an additional component to ensure long term stability of the measurement equipment.MethodsAt the time the HDR BT source is replaced, its Air Kerma Strength (SK) is measured. By comparing this value with the one obtained at the time of installation (corrected by decay), a clear determination of the stability of the measurement equipment can be performed.ResultsDifference between SK,vendor and SK,hosp as a function of the measurement date is reported for a 10 years' period. All measurements are well within the +/- 3% tolerance level recommended in current international guidelines. Percentage differences of SK,hosp values at the time of replacement compared to SK,hosp ones at the time when the source was installed are within the +/- 0.5% range, reflecting oscillations around a null deviation.ConclusionsThe method proposed allows any hospital to ensure a redundancy component of the long-term stability of all equipment involved in BT measurements in a very simple and time efficient manner. Additionally, it enables the hospital to maintain a detailed log of historical differences, facilitating the identification and correction of potential systematic deviations over time.
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Vijande, J., Ballester, F., Ouhib, Z., Granero, D., Pujades-Claumarchirant, M. C., & Perez-Calatayud, J. (2012). Dosimetry comparison between TG-43 and Monte Carlo calculations using the Freiburg flap for skin high-dose-rate brachytherapy. Brachytherapy, 11(6), 528–535.
Abstract: PURPOSE: The purpose of this work was to evaluate whether the delivered dose to the skin surface and at the prescription depth when using a Freiburg flap applicator is in agreement with the one predicted by the treatment planning system (TPS) using the TG-43 dose-calculation formalism. METHODS AND MATERIALS: Monte Carlo (MC) simulations and radiochromic film measurements have been performed to obtain dose distributions with the source located at the center of one of the spheres and between two spheres. Primary and scatter dose contributions were evaluated to understand the role played by the scatter component. A standard treatment plan was generated using MC- and TG-43-based TPS applying the superposition principle. RESULTS: The MC model has been validated by performing additional simulations in the same conditions but transforming air and Freiburg flap materials into water to match TG-43 parameters. Both dose distributions differ less than 1%. Scatter defect compared with TG-43 data is up to 15% when the source is located at the center of the sphere and up to 25% when the source is between two spheres. Maximum deviations between TPS- and MC-based distributions are of 5%. CONCLUSIONS: The deviations in the TG-43-based dose distributions for a standard treatment plan with respect to the MC dose distribution calculated taking into account the composition and shape of the applicator and the surrounding air are lower than 5%. Therefore, this study supports the validity of the TPS used in clinical practice. (C) 2012 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.
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Hueso-Gonzalez, F., Ballester, F., Perez-Calatayud, J., Siebert, F. A., & Vijande, J. (2017). Towards clinical application of RayStretch for heterogeneity corrections in LDR permanent I-125 prostate brachytherapy. Brachytherapy, 16(3), 616–623.
Abstract: PURPOSE: RayStretch is a simple algorithm proposed for heterogeneity corrections in low-dose-rate brachytherapy. It is built on top of TG-43 consensus data, and it has been validated with Monte Carlo (MC) simulations. In this study, we take a real clinical prostate implant with 71 1251 seeds as reference and we apply RayStretch to analyze its performance in worst-case scenarios. METHODS AND MATERIALS: To do so, we design two cases where large calcifications are located in the prostate lobules. RayStretch resilience under various calcification density values is also explored. Comparisons against MC calculations are performed. RESULTS: Dose volume histogram related parameters like prostate D-90, rectum D-2cc, or urethra D-10 obtained with RayStretch agree within a few percent with the detailed MC results for all cases considered. CONCLUSIONS: The robustness and compatibility of RayStretch with commercial treatment planning systems indicate its applicability in clinical practice for dosimetric corrections in prostate calcifications. Its use during intraoperative ultrasound planning is foreseen.
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Fernandez-Carames, T., Valcarce, A., & Vijande, J. (2010). Charged charmonium molecules. Phys. Rev. D, 82(5), 054032–5pp.
Abstract: We make use of a self-consistent quark-model based study of four-quark charmonium-like states to interpret recent charmonium experimental data. We conclude that there exists a D*(D) over bar* meson-meson molecule with quantum numbers (I-G) J(PC) = (1(-))2(++). Our study confirms the presence of charged charmonium-like resonances on the excited charmonium spectrum. We find support from recent experimental data by the Belle Collaboration [R. Mizuk et al. (Belle Collaboration), Phys. Rev. D 78, 072004 (2008)]. Confirmation of the experimental data by the Belle Collaboration and the determination of the quantum numbers of the new structures would help in discriminating among different theoretical models and would give further support to the theoretical analysis of T. Fernandez-Carames, A. Valcarce, and J. Vijande [Phys. Rev. Lett. 103, 222001 (2009)].
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Vijande, J., Valcarce, A., & Richard, J. M. (2012). Stability of hexaquarks in the string limit of confinement. Phys. Rev. D, 85(1), 014019–6pp.
Abstract: The stability of systems containing six quarks or antiquarks is studied within a simple string model inspired by the strong-coupling regime of quantum chromodynamics and used previously for tetraquarks and pentaquarks. We discuss both six-quark (q(6)) and three-quark-three-antiquark (q(3)($) over bar (3)) states. The quarks are assumed to be distinguishable and thus not submitted to antisymmetrization. It is found that the ground state of (q(6)) is stable against dissociation into two isolated baryons. For the case of (q(3)($) over bar (3)), our results indicate the existence of a bound state very close to the threshold. The investigations are extended to (q(3)Q(3)) and (Q(3) ($) over bar (3)) systems with two different constituent masses, and their stability is discussed as a function of the mass ratio.
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