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Author Barrientos, L.; Borja-Lloret, M.; Casaña, J.V.; Dendooven, P.; Garcia Lopez, J.G.; Hueso-Gonzalez, F.; Jiméeez-Ramos, M.C.; Perez-Curbelo, J.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G.
Title Gamma-ray sources imaging and test-beam results with MACACO III Compton camera Type Journal Article
Year 2024 Publication Physica Medica Abbreviated Journal Phys. Medica
Volume 117 Issue Pages 103199 - 10pp
Keywords Hadron therapy; Compton camera; Scintillator crystals; Silicon photomultipliers
Abstract Hadron therapy is a radiotherapy modality which offers a precise energy deposition to the tumors and a dose reduction to healthy tissue as compared to conventional methods. However, methods for real-time monitoring are required to ensure that the radiation dose is deposited on the target. The IRIS group of IFIC-Valencia developed a Compton camera prototype for this purpose, intending to image the Prompt Gammas emitted by the tissue during irradiation. The system detectors are composed of Lanthanum (III) bromide scintillator crystals coupled to silicon photomultipliers. After an initial characterization in the laboratory, in order to assess the system capabilities for future experiments in proton therapy centers, different tests were carried out in two facilities: PARTREC (Groningen, The Netherlands) and the CNA cyclotron (Sevilla, Spain). Characterization studies performed at PARTREC indicated that the detectors linearity was improved with respect to the previous version and an energy resolution of 5.2 % FWHM at 511 keV was achieved. Moreover, the imaging capabilities of the system were evaluated with a line source of 68Ge and a point-like source of 241Am-9Be. Images at 4.439 MeV were obtained from irradiation of a graphite target with an 18 MeV proton beam at CNA, to perform a study of the system potential to detect shifts at different intensities. In this sense, the system was able to distinguish 1 mm variations in the target position at different beam current intensities for measurement times of 1800 and 600 s.
Address [Barrientos, L.; Borja-Lloret, M.; Casana, J. V.; Hueso-Gonzalez, F.; Perez-Curbelo, J.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Luis.Barrientos@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Sci Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 1120-1797 ISBN Medium
Area Expedition Conference
Notes WOS:001145147400001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5892
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Author Barrientos, L.; Borja-Lloret, M.; Casana, J.V.; Hueso-Gonzalez, F.; Ros, A.; Roser, J.; Senra, C.; Solaz, C.; Viegas, R.; Llosa, G.
Title System characterization and performance studies with MACACO III Compton camera Type Journal Article
Year 2023 Publication Radiation Physics and Chemistry Abbreviated Journal Radiat. Phys. Chem.
Volume 208 Issue Pages 110922 - 13pp
Keywords Compton camera; Scintillator crystals; Silicon photomultipliers
Abstract The IRIS group of IFIC-Valencia has developed a Compton camera prototype. The system detectors are made of Lanthanum (III) bromide scintillator crystals coupled to silicon photomultipliers. Two models of silicon photomultipliers arrays with different micro pixel pitch (25 and 50 μm) have been chosen as possible candidates to improve the response of the new system. Characterization studies with a 22Na point-like source have indicated that the 25 μm photodetector provided better performance in terms of energy resolution (5.2% FWHM at 511 keV) and angular resolution (6.9 degrees FWHM at 1275 keV), and more stability with temperature variations. In addition, MACACO III imaging capabilities have been assessed using a structure composed of thirty-seven 22Na point-like sources. Furthermore, in order to evaluate possible ways of improving the system performance, several studies have been carried out by means of simulations both in realistic and performance improved conditions. In this work, the system performance is evaluated for its future application in different areas.
Address [Barrientos, L.; Borja-Lloret, M.; Casana, J. V.; Hueso-Gonzalez, F.; Ros, A.; Roser, J.; Senra, C.; Solaz, C.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IF, Valencia, Spain, Email: Luis.Barrientos@ific.uv.es;
Corporate Author Thesis
Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 0969-806x ISBN Medium
Area Expedition Conference
Notes WOS:000962800400001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 5511
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Author Scandale, W. et al; Lari, L.
Title Optimization of the crystal assisted collimation of the SPS beam Type Journal Article
Year 2013 Publication Physics Letters B Abbreviated Journal Phys. Lett. B
Volume 726 Issue 1-3 Pages 182-186
Keywords Accelerator; Beam collimation; Crystal; Channeling
Abstract The possibility for optimization of crystal assisted collimation has been studied at the CERN SPS for stored beams of protons and Pb ions with 270 GeV/c per unit charge. A bent silicon crystal used as a primary collimator deflects halo particles in the channeling regime, directing them into a tungsten absorber. In channeling conditions a strong reduction of off-momentum particle numbers produced in the crystal and absorber, which form collimation leakage, has been observed in the first high dispersion (HD) area downstream. The present study shows that the collimation leakage is minimal for some values of the absorber offset relative to the crystal. The optimal offset value is larger for Pb ions because of their considerably larger ionization losses in the crystal, which cause large increases of particle betatron oscillation amplitudes. The optimal absorber offset allows obtaining maximal efficiency of crystal-assisted collimation.
Address [Scandale, W.; Arduini, G.; Butcher, M.; Cerutti, F.; Gilardoni, S.; Lari, L.; Lechner, A.; Losito, R.; Masi, A.; Mereghetti, A.; Metral, E.; Mirarchi, D.; Montesano, S.; Redaelli, S.; Schoofs, P.; Smirnov, G.] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland, Email: alexander.taratin@cern.ch
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 0370-2693 ISBN Medium
Area Expedition Conference
Notes WOS:000326482200020 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1694
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Author Scandale, W. et al; Lari, L.
Title Observation of nuclear dechanneling length reduction for high energy protons in a short bent crystal Type Journal Article
Year 2015 Publication Physics Letters B Abbreviated Journal Phys. Lett. B
Volume 743 Issue Pages 440-443
Keywords Crystal; Channeling; Beam; Deflection
Abstract Deflection of 400 GeV/c protons by a short bent silicon crystal was studied at the CERN SPS. It was shown that the dechanneling probability increases while the dechanneling length decreases with an increase of incident angles of particles relative to the crystal planes. The observation of the dechanneling length reduction provides evidence of the particle population increase at the top levels of transverse energies in the potential well of the planar channels. (C) 2015 The Authors. Published by Elsevier B.V.
Address [Scandale, W.; Arduini, G.; Butcher, M.; Cerutti, F.; Garattini, M.; Gilardoni, S.; Lari, L.; Lechner, A.; Losito, R.; Masi, A.; Mereghetti, A.; Metral, E.; Mirarchi, D.; Montesano, S.; Redaelli, S.; Rossi, R.; Schoofs, P.; Smirnov, G.] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland, Email: alexander.taratin@cern.ch
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 0370-2693 ISBN Medium
Area Expedition Conference
Notes WOS:000352147500065 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 2201
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Author Olmo, G.J.; Rubiera-Garcia, D.
Title The quantum, the geon and the crystal Type Journal Article
Year 2015 Publication International Journal of Modern Physics D Abbreviated Journal Int. J. Mod. Phys. D
Volume 24 Issue 9 Pages 1542013 - 15pp
Keywords Effective geometries; crystalline structures; modified gravity; metric-affine approach; geons
Abstract Effective geometries arising from a hypothetical discrete structure of spacetime can play an important role in the understanding of the gravitational physics beyond General Relativity (GR). To discuss this question, we make use of lessons from crystalline systems within solid state physics, where the presence of defects in the discrete microstructure of the crystal determine the kind of effective geometry needed to properly describe the system in the macroscopic continuum limit. In this work, we study metric-affine theories with nonmetricity and torsion, which are the gravitational analog of crystalline structures with point defects and dislocations. We consider a crystal-motivated gravitational action and show the presence of topologically nontrivial structures (wormholes) supported by an electromagnetic field. Their existence has important implications for the quantum foam picture and the effective gravitational geometries. We discuss how the dialogue between solid state physics systems and modified gravitational theories can provide useful insights on both sides.
Address [Olmo, Gonzalo J.] Univ Valencia, CSIC, Fac Fis, Dept Fis Teor, E-46100 Valencia, Spain, Email: drubiera@fudan.edu.cn
Corporate Author Thesis
Publisher World Scientific Publ Co Pte Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 0218-2718 ISBN Medium
Area Expedition Conference
Notes WOS:000358793200014 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 2322
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Author Llosa, G.; Barrio, J.; Cabello, J.; Crespo, A.; Lacasta, C.; Rafecas, M.; Callier, S.; de la Taille, C.; Raux, L.
Title Detector characterization and first coincidence tests of a Compton telescope based on LaBr3 crystals and SiPMs Type Journal Article
Year 2012 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 695 Issue Pages 105-108
Keywords Hadron therapy; Compton imaging; LaBr3; Continuous crystal; SiPM; MPPC; G-APD
Abstract A Compton telescope for dose monitoring in hadron therapy consisting of several layers of continuous LaBr3 crystals coupled to silicon photomultiplier (SiPM) arrays is under development within the ENVISION project. In order to test the possibility of employing such detectors for the telescope, a detector head consisting of a continuous 16 mm x 18 mm x 5 mm LaBr3 crystal coupled to a SiPM array has been assembled and characterized, employing the SPIROC1 ASIC as readout electronics. The best energy resolution obtained at 511 key is 6.5% FWHM and the timing resolution is 3.1 ns FWHM. A position determination method for continuous crystals is being tested, with promising results. In addition, the detector has been operated in time coincidence with a second detector layer, to determine the coincidence capabilities of the system. The first tests are satisfactory, and encourage the development of larger detectors that will compose the telescope prototype.
Address [Llosa, G.; Barrio, J.; Cabello, J.; Crespo, A.; Lacasta, C.; Rafecas, M.] UVEG, CSIC, IFIC, Inst Fis Corpuscular, Valencia, Spain, Email: gabriela.llosa@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000311469900020 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1235
Permanent link to this record
 

 
Author Llosa, G.; Barrio, J.; Lacasta, C.; Callier, S.; Raux, L.; de La Taille, C.
Title First tests in the application of silicon photomultiplier arrays to dose monitoring in hadron therapy Type Journal Article
Year 2011 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 648 Issue Pages S96-S99
Keywords Hadron therapy; Compton imaging; LaBr3; Continuous crystal; SiPM; MPPC; G-APD
Abstract A detector head composed of a continuous LaBr3 crystal coupled to a silicon photomultiplier array has been mounted and tested, for its use in a Compton telescope for dose monitoring in hadron therapy. The LaBr3 crystal has 16 mm x 18 mm x 5 mm size, and it is surrounded with reflecting material in five faces. The SiPM array has 16 (4 x 4) elements of 3 mm x 3 mm size. The SPIROC1 ASIC has been employed as readout electronics. The detector shows a linear behavior up to 1275 keV. The energy resolution obtained at 511 keV is 7% FWHM, and it varies as one over the square root of the energy up to the energies tested. The variations among the detector channels are within 12%. A preliminary measurement of the timing resolution gives 7 ns FWHM. The spatial resolution obtained with the center of gravity method is 1.2 mm FWHM. The tests performed confirm the correct functioning of the detector.
Address [Llosa, G.; Barrio, J.; Lacasta, C.] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: gabriela.llosa@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000305376900026 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1068
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Author Llosa, G.; Barrillon, P.; Barrio, J.; Bisogni, M.G.; Cabello, J.; Del Guerra, A.; Etxebeste, A.; Gillam, J.E.; Lacasta, C.; Oliver, J.F.; Rafecas, M.; Solaz, C.; Stankova, V.; de La Taille, C.
Title High performance detector head for PET and PET/MR with continuous crystals and SiPMs Type Journal Article
Year 2013 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 702 Issue Pages 3-5
Keywords Monolithic crystals; SiPM; MG-APD; PET; High resolution; Position determination
Abstract A high resolution PET detector head for small animal PET applications has been developed. The detector is composed of a 12 mm x 12 mm continuous LYSO crystal coupled to a 64-channel monolithic SiPM matrix from FBK-irst. Crystal thicknesses of 5 mm and 10 mm have been tested, both yielding an intrinsic spatial resolution around 0.7 mm FWHM with a position determination algorithm that can also provide depth-of-interaction information. The detectors have been tested in a rotating system that makes it possible to acquire tomographic data and reconstruct images of Na-22 sources. An image reconstruction method specifically adapted for continuous crystals has been employed. The Full Width at Half Maximum measured from a point source reconstructed with ML-EM was 0.7 mm with the 5 mm crystal and 0.8 mm with the 10 mm crystal.
Address [Llosa, G.; Barrio, J.; Cabello, J.; Etxebeste, A.; Gillam, J. E.; Lacasta, C.; Oliver, J. F.; Rafecas, M.; Solaz, C.; Stankova, V.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: gabriela.llosa@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000314682300002 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1330
Permanent link to this record
 

 
Author Babiano, V.; Caballero, L.; Calvo, D.; Ladarescu, I.; Olleros, P.; Domingo-Pardo, C.
Title gamma-Ray position reconstruction in large monolithic LaCl3(Ce) crystals with SiPM readout Type Journal Article
Year 2019 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 931 Issue Pages 1-22
Keywords Gamma-ray; Position-sensitive detectors; Monolithic crystals; Spatial resolution; Neural networks
Abstract We report on the spatial response characterization of large LaCl3(Ce) monolithic crystals optically coupled to 8 x 8 pixel silicon photomultiplier (SiPM) sensors. A systematic study has been carried out for 511 keV gamma-rays using three different crystal thicknesses of 10 mm, 20 mm and 30 mm, all of them with planar geometry and a base size of 50 x 50 mm(2). In this work we investigate and compare two different approaches for the determination of the main gamma-ray hit location. On one hand, methods based on the fit of an analytical model for the scintillation light distribution provide the best results in terms of linearity and field of view, with spatial resolutions close to similar to 1 mm FWHM. On the other hand, position reconstruction techniques based on neural networks provide similar linearity and field-of-view, becoming the attainable spatial resolution similar to 3 mm FWHM. For the third space coordinate z or depth-of-interaction we have implemented an inverse linear calibration approach based on the cross-section of the measured scintillation-light distribution at a certain height. The detectors characterized in this work are intended for the development of so-called Total Energy Detectors with Compton imaging capability (i-TED), aimed at enhanced sensitivity and selectivity measurements of neutron capture cross sections via the time-of-flight (TOF) technique.
Address [Babiano, V; Caballero, L.; Calvo, D.; Ladarescu, I; Olleros, P.; Domingo-Pardo, C.] Univ Valencia, Inst Fis Corpuscular, CSIC, Valencia, Spain, Email: domingo@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000466151600001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 4015
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Author Babiano, V.; Balibrea, J.; Caballero, L.; Calvo, D.; Ladarescu, I.; Mira Prats, S.; Domingo-Pardo, C.
Title First i-TED demonstrator: A Compton imager with Dynamic Electronic Collimation Type Journal Article
Year 2020 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 953 Issue Pages 163228 - 9pp
Keywords Compton imaging; Position-sensitive detectors; Monolithic crystals; Silicon photomultiplier
Abstract i-TED consists of both a total energy detector and a Compton camera primarily intended for the measurement of neutron capture cross sections by means of the simultaneous combination of neutron time-of-flight (TOF) and gamma-ray imaging techniques. TOF allows one to obtain a neutron-energy differential capture yield, whereas the imaging capability is intended for the discrimination of radiative background sources, that have a spatial origin different from that of the capture sample under investigation. A distinctive feature of i-TED is the embedded Dynamic Electronic Collimation (DEC) concept, which allows for a trade-off between efficiency and image resolution. Here we report on some general design considerations and first performance characterization measurements made with an i-TED demonstrator in order to explore its gamma-ray detection and imaging capabilities.
Address [Babiano, V; Balibrea, J.; Caballero, L.; Calvo, D.; Ladarescu, I; Mira Prats, S.; Domingo-Pardo, C.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: domingo@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000506419900045 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 4250
Permanent link to this record