Abstract: The first observation of the semileptonic b-baryon decay Lambda(0)(b) -> Lambda(+)(c) tau(-)(nu) over bar (tau) with a significance of 6.1 sigma, is reported using a data sample corresponding to 3 fb(-1) of integrated luminosity, collected by the LHCb experiment at center-of-mass energies of 7 and 8 TeV at the LHC. The tau(-) lepton is reconstructed in the hadronic decay to three charged pions. The ratio K = B(Lambda(0)(b) -> Lambda(+)(c) tau(-)(nu) over bar (tau))/B(Lambda(0)(b) -> Lambda(+)(c)pi(-)pi(+)pi(-)) is measured to be 2.46 +/- 0.27 +/- 0.40, where the first uncertainty is statistical and the second systematic. The branching fraction B(Lambda(0)(b) -> Lambda(+)(c) tau(-)(nu) over bar (tau)) (1.50 +/- 0.16 +/- 0.25 +/- 0.23)% is obtained, where the third uncertainty is from the external branching fraction of the normalization channel Lambda(0)(b) -> Lambda(+)(c)pi(-)pi(+)pi(-). The ratio of semileptonic branching fractions R(Lambda(+)(c)) B(Lambda(0)(b) -> Lambda(+)(c) tau(-)(nu) over bar (tau))/B(Lambda(0)(b) -> Lambda(+)(c)mu(-)(nu) over bar (tau)) is derived to be 0.242 +/- 0.026 +/- 0.040 +/- 0.059, where the external branching fraction uncertainty from the channel Lambda(0)(b) -> Lambda(+)(c)mu(-)(nu) over bar (tau) contributes to the last term. This result is in agreement with the standard model prediction.

Abstract: The first observations of B-0 -> (D) over bar*(2007)K-0(+)pi(-) and B-s(0) -> (D) over bar*(2007)K-0(-)pi(+) decays are presented, and their branching fractions relative to that of the B ->( D) over bar* (2007)(0)pi(+)pi(-) decay are reported. These modes can potentially be used to investigate the spectroscopy of charm and charm-strange resonances and to determine the angle gamma of the Cabibbo-Kobayashi-Maskawa unitarity triangle. It is also important to understand them as a source of potential background in determinations of gamma from B+ -> DK+ and B-0 -> DK+pi(-) decays. The analysis is based on a sample corresponding to an integrated luminosity of 5.4 fb(-1 )of proton-proton collision data at 13 TeV center-of-mass energy recorded with the LHCb detector. The (D) over bar*(2007)(0) mesons are fully reconstructed in the (D) over bar (0)pi(0) and (D) over bar (0)gamma channels with the (D) over bar (0) -> K+pi(-) decay. A novel weighting method is used to subtract background while simultaneously applying an event-by-event efficiency correction to account for resonant structures in the decays.

Abstract: We present the first lattice study of pion-pion scattering with varying number of colors, N-c. We use lattice simulations with four degenerate quark flavors, N-f = 4, and N-c= 3 – 6. We focus on two scattering channels that do not involve vacuum diagrams. These correspond to two irreducible representations of the SU(4) flavor group: the fully symmetric one, SS, and the fully antisymmetric one, AA. The former is a repulsive channel equivalent to the isospin-2 channel of SU(2). By contrast, the latter is attractive and only exists for N-f >= 4. A representative state is (vertical bar D-s(+) pi(+)> – vertical bar D+ K+ >) /root 2. Using Lfischer's formalism, we extract the near-threshold scattering amplitude and we match our results to Chiral Perturbation Theory (ChPT) at large N-c. For this, we compute the analytical U(N-f) ChPT prediction for two-pion scattering, and use the lattice results to constrain the N-c scaling of the relevant low-energy couplings.

Abstract: The Deep Underground Neutrino Experiment (DUNE) will produce world-leading neutrino oscillation measurements over the lifetime of the experiment. In this work, we explore DUNE's sensitivity to observe charge-parity violation (CPV) in the neutrino sector, and to resolve the mass ordering, for exposures of up to 100 kiloton-megawatt-calendar years (kt-MW-CY), where calendar years include an assumption of 57% accelerator uptime based on past accelerator performance at Fermilab. The analysis includes detailed uncertainties on the flux prediction, the neutrino interaction model, and detector effects. We demonstrate that DUNE will be able to unambiguously resolve the neutrino mass ordering at a 4 sigma (5 sigma) level with a 66 (100) kt-MW-CY far detector exposure, and has the ability to make strong statements at significantly shorter exposures depending on the true value of other oscillation parameters, with a median sensitivity of 3 sigma for almost all true delta(CP) values after only 24 kt-MW-CY. We also show that DUNE has the potential to make a robust measurement of CPV at a 3 sigma level with a 100 kt-MW-CY exposure for the maximally CP-violating values delta(CP) = +/-pi/2. Additionally, the dependence of DUNE's sensitivity on the exposure taken in neutrino-enhanced and antineutrino-enhanced running is discussed. An equal fraction of exposure taken in each beam mode is found to be close to optimal when considered over the entire space of interest.

Abstract: Purpose This work aims to simulate clustered DNA damage from ionizing radiation and estimate the relative biological effectiveness (RBE) for radionuclide (rBT)- and electronic (eBT)-based surface brachytherapy through a hybrid Monte Carlo (MC) approach, using realistic models of the sources and applicators. Methods Damage from ionizing radiation has been studied using the Monte Carlo Damage Simulation algorithm using as input the primary electron fluence simulated using a state-of-the-art MC code, PENELOPE-2018. Two Ir-192 rBT applicators, Valencia and Leipzig, one Co-60 source with a Freiburg Flap applicator (reference source), and two eBT systems, Esteya and INTRABEAM, have been included in this study implementing full realizations of their geometries as disclosed by the manufacturer. The role played by filtration and tube kilovoltage has also been addressed. Results For rBT, an RBE value of about 1.01 has been found for the applicators and phantoms considered. In the case of eBT, RBE values for the Esteya system show an almost constant RBE value of about 1.06 for all depths and materials. For INTRABEAM, variations in the range of 1.12-1.06 are reported depending on phantom composition and depth. Modifications in the Esteya system, filtration, and tube kilovoltage give rise to variations in the same range. Conclusions Current clinical practice does not incorporate biological effects in surface brachytherapy. Therefore, the same absorbed dose is administered to the patients independently on the particularities of the rBT or eBT system considered. The almost constant RBE values reported for rBT support that assumption regardless of the details of the patient geometry, the presence of a flattening filter in the applicator design, or even significant modifications in the photon energy spectra above 300 keV. That is not the case for eBT, where a clear dependence on the eBT system and the characteristics of the patient geometry are reported. A complete study specific for each eBT system, including detailed applicator characteristics (size, shape, filtering, among others) and common anatomical locations, should be performed before adopting an existing RBE value.