Abstract: We present global fits of the constrained Minimal Supersymmetric Standard Model (cMSSM) and the Non-Universal Higgs Model (NUHM), including the most recent CMS constraint on the Higgs boson mass, 5.8 fb(-1) integrated luminosity null Supersymmetry searches by ATLAS, the new LHCb measurement of B R ((B) over bar (s) -> mu(+) mu(-)) and the 7-year WMAP dark matter relic abundance determination. We include the latest dark matter constraints from the XENON100 experiment, marginalising over astrophysical and particle physics uncertainties. We present Bayesian posterior and profile likelihood maps of the highest resolution available today, obtained from up to 350M points. We find that the new constraint on the Higgs boson mass has a dramatic impact, ruling out large regions of previously favoured cMSSM and NUHM parameter space. In the cMSSM, light sparticles and predominantly gaugino-like dark matter with a mass of a few hundred GeV are favoured. The NUHM exhibits a strong preference for heavier sparticle masses and a Higgsino-like neutralino with a mass of 1 TeV. The future ton-scale XENON1T direct detection experiment will probe large portions of the currently favoured cMSSM and NUHM parameter space. The LHC operating at 14 TeV collision energy will explore the favoured regions in the cMSSM, while most of the regions favoured in the NUHM will remain inaccessible. Our best-fit points achieve a satisfactory quality-of-fit, with p-values ranging from 0.21 to 0.35, so that none of the two models studied can be presently excluded at any meaningful significance level.

Abstract: Recent results from a measurement campaign studying the isomerism in neutron-deficient Tl isotopes are presented. The measurements make use of a nuclear spectroscopy setup coupled to the high-resolution Penningtrap mass spectrometer ISOLTRAP at CERN's radioactive ion-beam facility ISOLDE. The mass values of Tl-190,Tl-194 are improved and a mass-spin-state assignment is carried out. An additional mass measurement of the grandparent nuclide At-198 allows the deduction of the spin-state ordering in Tl-190. As a result, the excitation energies of the isomers in both Tl isotopes are determined for the first time to Eex(Tl-194) = 260(15) keV and E-ex(Tl-190) = 89(12) keV. Furthermore, this allows anchoring of the ground-state and isomer masses of Bi-194, Fr-202, and Ac-206, which are linked by two independent a-decay chains.

Abstract: Ru-116 and Ru-118 have been studied via beta-delayed gamma-ray spectroscopy of nuclei produced in fragmentation reactions at the Radioactive Ion-Beam Factory (RIBF) facility. Level schemes with positive-parity states up to spin J = 6 have been constructed. The results have been discussed in terms of the interacting boson model, the algebraic collective model, and total Routhian surfaces. We conclude that the very neutron-rich nuclei still show many features associated with triaxial gamma-soft nuclei, represented by the O(6) symmetry, but are approaching a spherical structure, the U(5) symmetry, with increasing neutron number towards the N = 82 shell closure. In Ru-118, hints of a shape transition in the ground state have been observed.

Abstract: While standard solar model (SSM) predictions depend on approximately 20 input parameters, SSM neutrino flux predictions are strongly correlated with a single model output parameter, the core temperature T-c. Consequently, one can extract physics from solar neutrino flux measurements while minimizing the consequences of SSM uncertainties, by studying flux ratios with appropriate power-law weightings tuned to cancel this T-c dependence. We reexamine an idea for constraining the primordial C + N content of the solar core from a ratio of CN-cycle O-15 to pp-chain B-8 neutrino fluxes, showing that non-nuclear SSM uncertainties in the ratio are small and effectively governed by a single parameter, the diffusion coefficient. We point out that measurements of both CN-I cycle neutrino branches-O-15 and N-13 beta-decay-could, in principle, lead to separate determinations of the core C and N abundances, due to out-of-equilibrium CN-cycle burning in the cooler outer layers of the solar core. Finally, we show that the strategy of constructing “minimum uncertainty” neutrino flux ratios can also test other properties of the SSM. In particular, we demonstrate that a weighted ratio of Be-7 and B-8 fluxes constrains a product of S-factors to the same precision currently possible with laboratory data.

Abstract: The immune system should constitute a strong selective pressure promoting viral genetic diversity and evolution. However, HIV shows lower sequence variability at T-cell epitopes than elsewhere in the genome, in contrast with other human RNA viruses. Here, we propose that epitope conservation is a consequence of the particular interactions established between HIV and the immune system. On one hand, epitope recognition triggers an anti-HIV response mediated by cytotoxic T-lymphocytes (CTLs), but on the other hand, activation of CD4(+) helper T lymphocytes (T-H cells) promotes HIV replication. Mathematical modeling of these opposite selective forces revealed that selection at the intrapatient level can promote either T-cell epitope conservation or escape. We predict greater conservation for epitopes contributing significantly to total immune activation levels (immunodominance), and when T-H cell infection is concomitant to epitope recognition (transinfection). We suggest that HIV-driven immune activation in the lymph nodes during the chronic stage of the disease may offer a favorable scenario for epitope conservation. Our results also support the view that some pathogens draw benefits from the immune response and suggest that vaccination strategies based on conserved T-H epitopes may be counterproductive.