Records |
Author |
Brzezinski, K.; Oliver, J.F.; Gillam, J.; Rafecas, M. |
Title |
Study of a high-resolution PET system using a Silicon detector probe |
Type |
Journal Article |
Year |
2014 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
Volume |
59 |
Issue |
20 |
Pages |
6117-6140 |
Keywords |
PET; high-resolution imaging; Si detectors; PET insert |
Abstract |
A high-resolution silicon detector probe, in coincidence with a conventional PET scanner, is expected to provide images of higher quality than those achievable using the scanner alone. Spatial resolution should improve due to the finer pixelization of the probe detector, while increased sensitivity in the probe vicinity is expected to decrease noise. A PET-probe prototype is being developed utilizing this principle. The system includes a probe consisting of ten layers of silicon detectors, each a 80 x 52 array of 1 x 1 x 1 mm(3) pixels, to be operated in coincidence with a modern clinical PET scanner. Detailed simulation studies of this system have been performed to assess the effect of the additional probe information on the quality of the reconstructed images. A grid of point sources was simulated to study the contribution of the probe to the system resolution at different locations over the field of view (FOV). A resolution phantom was used to demonstrate the effect on image resolution for two probe positions. A homogeneous source distribution with hot and cold regions was used to demonstrate that the localized improvement in resolution does not come at the expense of the overall quality of the image. Since the improvement is constrained to an area close to the probe, breast imaging is proposed as a potential application for the novel geometry. In this sense, a simplified breast phantom, adjacent to heart and torso compartments, was simulated and the effect of the probe on lesion detectability, through measurements of the local contrast recovery coefficient-to-noise ratio (CNR), was observed. The list-mode ML-EM algorithm was used for image reconstruction in all cases. As expected, the point spread function of the PET-probe system was found to be non-isotropic and vary with position, offering improvement in specific regions. Increase in resolution, of factors of up to 2, was observed in the region close to the probe. Images of the resolution phantom showed visible improvement in resolution when including the probe in the simulations. The image quality study demonstrated that contrast and spill-over ratio in other areas of the FOV were not sacrificed for this enhancement. The CNR study performed on the breast phantom indicates increased lesion detectability provided by the probe. |
Address |
[Brzezinski, K.; Oliver, J. F.; Gillam, J.; Rafecas, M.] Univ Valencia, CSIC, Inst Fis Corpuscular, E-46980 Valencia, Spain, Email: brzezinski@ific.uv.es |
Corporate Author |
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Thesis |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000343092300011 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
1963 |
Permanent link to this record |
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Author |
Babiano, V.; Caballero, L.; Calvo, D.; Ladarescu, I.; Olleros, P.; Domingo-Pardo, C. |
Title |
gamma-Ray position reconstruction in large monolithic LaCl3(Ce) crystals with SiPM readout |
Type |
Journal Article |
Year |
2019 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
Volume |
931 |
Issue |
|
Pages |
1-22 |
Keywords |
Gamma-ray; Position-sensitive detectors; Monolithic crystals; Spatial resolution; Neural networks |
Abstract |
We report on the spatial response characterization of large LaCl3(Ce) monolithic crystals optically coupled to 8 x 8 pixel silicon photomultiplier (SiPM) sensors. A systematic study has been carried out for 511 keV gamma-rays using three different crystal thicknesses of 10 mm, 20 mm and 30 mm, all of them with planar geometry and a base size of 50 x 50 mm(2). In this work we investigate and compare two different approaches for the determination of the main gamma-ray hit location. On one hand, methods based on the fit of an analytical model for the scintillation light distribution provide the best results in terms of linearity and field of view, with spatial resolutions close to similar to 1 mm FWHM. On the other hand, position reconstruction techniques based on neural networks provide similar linearity and field-of-view, becoming the attainable spatial resolution similar to 3 mm FWHM. For the third space coordinate z or depth-of-interaction we have implemented an inverse linear calibration approach based on the cross-section of the measured scintillation-light distribution at a certain height. The detectors characterized in this work are intended for the development of so-called Total Energy Detectors with Compton imaging capability (i-TED), aimed at enhanced sensitivity and selectivity measurements of neutron capture cross sections via the time-of-flight (TOF) technique. |
Address |
[Babiano, V; Caballero, L.; Calvo, D.; Ladarescu, I; Olleros, P.; Domingo-Pardo, C.] Univ Valencia, Inst Fis Corpuscular, CSIC, Valencia, Spain, Email: domingo@ific.uv.es |
Corporate Author |
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Thesis |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000466151600001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
no |
Call Number |
IFIC @ pastor @ |
Serial |
4015 |
Permanent link to this record |
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Author |
Andricek, L. et al; Lacasta, C.; Marinas, C.; Vos, M. |
Title |
Intrinsic resolutions of DEPFET detector prototypes measured at beam tests |
Type |
Journal Article |
Year |
2011 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
Volume |
638 |
Issue |
1 |
Pages |
24-32 |
Keywords |
Silicon pixel detector; Detector resolution; Spatial resolution; DEPFET; Beam test |
Abstract |
The paper is based on the data of the 2009 DEPFET beam test at CERN SPS. The beam test used beams of pions and electrons with energies between 40 and 120 GeV, and the sensors tested were prototypes with thickness of 450 μm and pixel pitch between 20 and 32 μm. Intrinsic resolutions of the detectors are calculated by disentangling the contributions of measurement errors and multiple scattering in tracking residuals. Properties of the intrinsic resolution estimates and factors that influence them are discussed. For the DEPFET detectors in the beam test, the calculation yields intrinsic resolutions of approximate to 1 μm, with a typical accuracy of 0.1 μm. Bias scan, angle scan, and energy scan are used as example studies to show that the intrinsic resolutions are a useful tool in studies of detector properties. With sufficiently precise telescopes, detailed resolution maps can be constructed and used to study and optimize detector performance. |
Address |
[Dolezal, Z.; Drasal, Z.; Kodys, P.; Kvasnicka, P.; Malina, L.; Scheirich, J.] Charles Univ Prague, Fac Math & Phys, Inst Particle & Nucl Phys, CR-18000 Prague, Czech Republic, Email: peter.kodys@mff.cuni.cz |
Corporate Author |
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Thesis |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
|
Notes |
ISI:000290082600005 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
618 |
Permanent link to this record |
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Author |
Aliaga, R.J. |
Title |
Real-Time Estimation of Zero Crossings of Sampled Signals for Timing Using Cubic Spline Interpolation |
Type |
Journal Article |
Year |
2017 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
Volume |
64 |
Issue |
8 |
Pages |
2414-2422 |
Keywords |
Digital arithmetic; digital circuits; digital timing; field-programmable gate array (FPGA); interpolation; signal processing algorithms; splines time estimation; time resolution |
Abstract |
A scheme is proposed for hardware estimation of the location of zero crossings of sampled signals with subsample resolution for timing applications, which consists of interpolating the signal with a cubic spline near the zero crossing and then finding the root of the resulting polynomial. An iterative algorithm based on the bisection method is presented that obtains one bit of the result per step and admits an efficient digital implementation using fixed-point representation. In particular, the root estimation iteration involves only two additions, and the initial values can be obtained from finite impulse response (FIR) filters with certain symmetry properties. It is shown that this allows online real-time estimation of timestamps in free-running sampling detector systems with improved accuracy with respect to the more common linear interpolation. The method is evaluated with simulations using ideal and real timing signals, and estimates are given for the resource usage and speed of its implementation. |
Address |
[Aliaga, Ramon J.] Inst Fis Corpuscular, Paterna 46980, Spain, Email: raalva@upvnet.upv.es |
Corporate Author |
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Thesis |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0018-9499 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000411027700008 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
no |
Call Number |
IFIC @ pastor @ |
Serial |
3301 |
Permanent link to this record |
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Author |
Albiol, F.; Corbi, A.; Albiol, A. |
Title |
Evaluation of modern camera calibration techniques for conventional diagnostic X-ray imaging settings |
Type |
Journal Article |
Year |
2017 |
Publication |
Radiological Physics and Technology |
Abbreviated Journal |
Radiol. Phys. Technol. |
Volume |
10 |
Issue |
1 |
Pages |
68-81 |
Keywords |
Conventional X-ray camera calibration; Detector resolution; Intrinsic and extrinsic parameters; Zhang's method; Direct linear transform; Tsai's approach |
Abstract |
We explore three different alternatives for obtaining intrinsic and extrinsic parameters in conventional diagnostic X-ray frameworks: the direct linear transform (DLT), the Zhang method, and the Tsai approach. We analyze and describe the computational, operational, and mathematical background differences for these algorithms when they are applied to ordinary radiograph acquisition. For our study, we developed an initial 3D calibration frame with tin cross-shaped fiducials at specific locations. The three studied methods enable the derivation of projection matrices from 3D to 2D point correlations. We propose a set of metrics to compare the efficiency of each technique. One of these metrics consists of the calculation of the detector pixel density, which can be also included as part of the quality control sequence in general X-ray settings. The results show a clear superiority of the DLT approach, both in accuracy and operational suitability. We paid special attention to the Zhang calibration method. Although this technique has been extensively implemented in the field of computer vision, it has rarely been tested in depth in common radiograph production scenarios. Zhang's approach can operate on much simpler and more affordable 2D calibration frames, which were also tested in our research. We experimentally confirm that even three or four plane-image correspondences achieve accurate focal lengths. |
Address |
[Albiol, Francisco; Corbi, Alberto] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: alberto.corbi@ific.uv.es |
Corporate Author |
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Thesis |
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Publisher |
Springer Japan Kk |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1865-0333 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000405867100009 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
no |
Call Number |
IFIC @ pastor @ |
Serial |
3238 |
Permanent link to this record |