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Author  |
Cabello, J.; Etxebeste, A.; Llosa, G.; Ziegler, S.I. |
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Title |
Simulation study of PET detector limitations using continuous crystals |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
60 |
Issue |
9 |
Pages |
3673-3694 |
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Keywords |
continuous crystals; parallax effects; depth of interaction; high resolution; small animal PET |
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Abstract |
Continuous crystals can potentially obtain better intrinsic detector spatial resolution compared to pixelated crystals, additionally providing depth of interaction (DoI) information from the light distribution. To achieve high performance sophisticated interaction position estimation algorithms are required. There are a number of algorithms in the literature applied to different crystal dimensions and different photodetectors. However, the different crystal properties and photodetector array geometries have an impact on the algorithm performance. In this work we analysed, through Monte Carlo simulations, different combinations of realistic crystals and photodetector parameters to better understand their influence on the interaction position estimation accuracy, with special emphasis on the DoI. We used an interaction position estimation based on an analytical model for the present work. Different photodetector granulation schemes were investigated. The impact of the number of crystal faces readout by photodetectors was studied by simulating scenarios with one and two photodetectors. In addition, crystals with different levels of reflection and aspect ratios (AR) were analysed. Results showed that the impact of photodetector granularity is mainly shown near the edges and specially in the corners of the crystal. The resulting intrinsic spatial resolution near the centre with a 12 x 12 x 10 mm(3) LYSO crystal was 0.7-0.9 mm, while the average spatial resolution calculated on the entire crystal was 0.77 +/- 0.18 mm for all the simulated geometries with one and two photodetectors. Having front and back photodetectors reduced the DoI bias (Euclidean distance between estimated DoI and real DoI) and improved the transversal resolution near the corners. In scenarios with one photodetector, small AR resulted in DoI inaccuracies for absorbed events at the entrance of the crystal. These inaccuracies were slightly reduced either by increasing the AR or reducing the amount of reflected light, and highly mitigated using two photodetectors. Using one photodetector, we obtained a piecewise DoI error model with a DoI resolution of 0.4-0.9 mm for a 1.2 AR crystal, and we observed that including a second photodetector or reducing the amount of reflections reduced the DoI bias but did not significantly improve the DoI resolution. Translating the piecewise DoI error model obtained in this study to image reconstruction we obtained a spatial resolution variability of 0.39 mm using 85% of the FoV, compared to 2.59 mm and 1.87 mm without DoI correction or with a dual layer system, respectively. |
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[Cabello, Jorge; Ziegler, Sibylle I.] Tech Univ Munich, Klinikum Rechts Isar, Nukl Med Klin & Poliklin, D-80290 Munich, Germany, Email: jorge.cabello@tum.de |
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Iop Publishing Ltd |
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English |
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0031-9155 |
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Notes |
WOS:000354104700019 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2226 |
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Author |
Campanario, F.; Rauch, M.; Sapeta, S. |
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Title |
ZZ production at high transverse momenta beyond NLO QCD |
Type |
Journal Article |
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Year |
2015 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
08 |
Issue |
8 |
Pages |
070 - 25pp |
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Abstract |
We study the production of the four-lepton final state l+l−l+l−, predominantly produced by a pair of electroweak Z bosons, ZZ. Using the LoopSim method, we merge NLO QCD results for ZZ and ZZ+jet and obtain approximate NNLO predictions for ZZ production. The exact gluon-fusion loop-squared contribution to the ZZ process is also included. On top of that, we add to our merged sample the gluon-fusion ZZ+jet contributions from the gluon-gluon channel, which is formally of N^3LO and provides approximate results at NLO for the gluon-fusion mechanism. The predictions are obtained with the VBFNLO package and include the leptonic decays of the Z bosons with all off-shell and spin-correlation effects, as well as virtual photon contributions. We compare our predictions with existing results for the total inclusive cross section at NNLO and find a very good agreement. Then, we present results for differential distributions for two experimental setups, one used in searches for anomalous triple gauge boson couplings, the other in Higgs analyses in the four charged-lepton final state channel. We find that the approximate NNLO corrections are large, reaching up to 20% at high transverse momentum of the Z boson or the leading lepton, and are not covered by the NLO scale uncertainties. Distributions of the four-lepton invariant mass are, however, stable with respect to QCD corrections at this order. |
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no |
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yes |
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yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2595 |
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Author |
Campanario, F.; Roth, R.; Zeppenfeld, D. |
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Title |
QCD radiation in WH and WZ production and anomalous coupling measurements |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
91 |
Issue |
5 |
Pages |
054039 - 10pp |
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Abstract |
We study QCD radiation for the WH and WZ production processes at the LHC. We identify the regions sensitive to anomalous couplings, by considering jet observables, computed at next-to-leading-order QCD with the use of the Monte Carlo program VBFNLO. Based on these observations, we propose the use of a dynamical jet veto. The dynamical jet veto avoids the problem of large logarithms depending on the veto scale, hence providing more reliable predictions and simultaneously increasing the sensitivity to anomalous coupling searches, especially in the WZ production process. |
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Address |
[Campanario, Francisco] Univ Valencia, CSIC, IFIC, Theory Div, E-46980 Paterna, Valencia, Spain, Email: francisco.campanario@ific.uv.es; |
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Amer Physical Soc |
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English |
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ISSN |
1550-7998 |
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Notes |
WOS:000352062400002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2173 |
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Author |
Candela-Juan, C.; Ballester, F.; Perez-Calatayud, J.; Vijande, J. |
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Title |
Assaying multiple I-125 seeds with the well-ionization chamber SourceCheck(4 Pi) 33005 and a new insert |
Type |
Journal Article |
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Year |
2015 |
Publication |
Journal of Contemporary Brachytherapy |
Abbreviated Journal |
J. Contemp. Brachytherapy |
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Volume |
7 |
Issue |
6 |
Pages |
492-496 |
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Keywords |
brachytherapy; insert; quality assurance; prostate; seeds; well chamber |
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Abstract |
Purpose: To provide a practical solution that can be adopted in clinical routine to fulfill the AAPM-ESTRO recommendations regarding quality assurance of seeds used in prostate permanent brachytherapy. The aim is to design a new insert for the well-ionization chamber SourceCheck(4 Pi) 33005 (PTW, Germany) that allows evaluating the mean air-kerma strength of up to ten I-125 seeds with one single measurement instead of measuring each seed individually. Material and methods: The material required is: a) the SourceCheck(4 Pi) 33005 well-ionization chamber provided with a PTW insert to measure the air-kerma strength S-K of one single seed at a time; b) a newly designed insert that accommodates ten seeds in one column, which allows measuring the mean S-K of the ten seeds in one single measurement; and c) a container with ten seeds from the same batch and class of the seeds used for the patient implant, and a set of nine non-radioactive seeds.The new insert is characterized by determining its calibration coefficient, used to convert the reading of the well-chamber when ten seeds are measured to their mean S-K. The proposed method is validated by comparing the mean S-K of the ten seeds obtained from the new insert with the individual measurement of S-K of each seed, evaluated with the PTW insert. Results: The ratio between the calibration coefficient of the new insert and the calibration coefficient of the PTW insert for the SourceCheck(4 Pi) 33005 is 1.135 +/- 0.007 (k = 1). The mean S-K of a set of ten seeds evaluated with this new system is in agreement with the mean value obtained from measuring independently the S-K of each seed. Conclusions: The new insert and procedure allow evaluating the mean S-K of ten seeds prior to the implant in a single measurement. The method is faster and more efficient from radiation protection point of view than measuring the individual S-K of each seed. |
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Address |
[Candela-Juan, Cristian; Perez-Calatayud, Jose] La Fe Univ, Dept Radiat Oncol, Phys Sect, E-46026 Valencia, Spain, Email: ccanjuan@gmail.com |
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Publisher |
Termedia Publishing House Ltd |
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English |
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ISSN |
1689-832x |
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Notes |
WOS:000368381300010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
2533 |
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Author |
Candela-Juan, C.; Vijande, J.; Garcia-Martinez, T.; Niatsetski, Y.; Nauta, G.; Schuurman, J.; Ouhib, Z.; Ballester, F.; Perez-Calatayud, J. |
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Title |
Comparison and uncertainty evaluation of different calibration protocols and ionization chambers for low-energy surface brachytherapy dosimetry |
Type |
Journal Article |
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Year |
2015 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
42 |
Issue |
8 |
Pages |
4954-4964 |
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Keywords |
x-ray beams; electronic brachytherapy; surface applicators; dosimetry; uncertainty |
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Abstract |
Purpose: A surface electronic brachytherapy (EBT) device is in fact an x-ray source collimated with specific applicators. Low-energy (<100 kVp) x-ray beam dosimetry faces several challenges that need to be addressed. A number of calibration protocols have been published for x-ray beam dosimetry. The media in which measurements are performed are the fundamental difference between them. The aim of this study was to evaluate the surface dose rate of a low-energy x-ray source with small field applicators using different calibration standards and different small-volume ionization chambers, comparing the values and uncertainties of each methodology. Methods: The surface dose rate of the EBT unit Esteya (Elekta Brachytherapy, The Netherlands), a 69.5 kVp x-ray source with applicators of 10, 15, 20, 25, and 30 mm diameter, was evaluated using the AAPM TG-61 (based on air kerma) and International Atomic Energy Agency (IAEA) TRS-398 (based on absorbed dose to water) dosimetry protocols for low-energy photon beams. A plane parallel T34013 ionization chamber (PTW Freiburg, Germany) calibrated in terms of both absorbed dose to water and air kerma was used to compare the two dosimetry protocols. Another PTW chamber of the same model was used to evaluate the reproducibility between these chambers. Measurements were also performed with two different Exradin A20 (Standard Imaging, Inc., Middleton, WI) chambers calibrated in terms of air kerma. Results: Differences between surface dose rates measured in air and in water using the T34013 chamber range from 1.6% to 3.3%. No field size dependence has been observed. Differences are below 3.7% when measurements with the A20 and the T34013 chambers calibrated in air are compared. Estimated uncertainty (with coverage factor k = 1) for the T34013 chamber calibrated in water is 2.2%-2.4%, whereas it increases to 2.5% and 2.7% for the A20 and T34013 chambers calibrated in air, respectively. The output factors, measured with the PTW chambers, differ by less than 1.1% for any applicator size when compared to the output factors that were measured with the A20 chamber. Conclusions: Measurements using both dosimetric protocols are consistent, once the overall uncertainties are considered. There is also consistency between measurements performed with both chambers calibrated in air. Both the T34013 and A20 chambers have negligible stem effect. Any x-ray surface brachytherapy system, including Esteya, can be characterized using either one of these calibration protocols and ionization chambers. Having less correction factors, lower uncertainty, and based on measurements, performed in closer to clinical conditions, the TRS-398 protocol seems to be the preferred option. |
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Address |
[Candela-Juan, C.; Perez-Calatayud, J.] La Fe Univ, Dept Radiat Oncol, Valencia 46026, Spain, Email: ccanjuan@gmail.com |
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Amer Assoc Physicists Medicine Amer Inst Physics |
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English |
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ISSN |
0094-2405 |
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Notes |
WOS:000358933000051 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2323 |
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Author |
Cauchi, M.; Assmann, R.W.; Bertarelli, A.; Carra, F.; Cerutti, F.; Lari, L.; Redaelli, S.; Mollicone, P.; Sammut, N. |
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Title |
Thermomechanical response of Large Hadron Collider collimators to proton and ion beam impacts |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physical Review Special Topics-Accelerators and Beams |
Abbreviated Journal |
Phys. Rev. Spec. Top.-Accel. Beams |
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Volume |
18 |
Issue |
4 |
Pages |
041002 - 14pp |
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Keywords |
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Abstract |
The CERN Large Hadron Collider (LHC) is designed to accelerate and bring into collision high-energy protons as well as heavy ions. Accidents involving direct beam impacts on collimators can happen in both cases. The LHC collimation system is designed to handle the demanding requirements of high-intensity proton beams. Although proton beams have 100 times higher beam power than the nominal LHC lead ion beams, specific problems might arise in case of ion losses due to different particle-collimator interaction mechanisms when compared to protons. This paper investigates and compares direct ion and proton beam impacts on collimators, in particular tertiary collimators (TCTs), made of the tungsten heavy alloy INERMET (R) 180. Recent measurements of the mechanical behavior of this alloy under static and dynamic loading conditions at different temperatures have been done and used for realistic estimates of the collimator response to beam impact. Using these new measurements, a numerical finite element method (FEM) approach is presented in this paper. Sequential fast-transient thermostructural analyses are performed in the elastic-plastic domain in order to evaluate and compare the thermomechanical response of TCTs in case of critical beam load cases involving proton and heavy ion beam impacts. |
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Address |
[Cauchi, Marija; Assmann, R. W.; Bertarelli, A.; Carra, F.; Cerutti, F.; Lari, L.; Redaelli, S.] CERN, CH-1211 Geneva 23, Switzerland, Email: marija.cauchi@cern.ch |
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Amer Physical Soc |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1098-4402 |
ISBN |
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Area |
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Conference |
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Notes |
WOS:000352473800001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2180 |
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Author |
Cauchi, M.; Assmann, R.W.; Bertarelli, A.; Carra, F.; Lari, L.; Rossi, A.; Mollicone, P.; Sammut, N. |
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Title |
Thermomechanical assessment of the effects of a jaw-beam angle during beam impact on Large Hadron Collider collimators |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physical Review Special Topics-Accelerators and Beams |
Abbreviated Journal |
Phys. Rev. Spec. Top.-Accel. Beams |
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Volume |
18 |
Issue |
2 |
Pages |
021001 - 14pp |
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Keywords |
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Abstract |
The correct functioning of a collimation system is crucial to safely and successfully operate high-energy particle accelerators, such as the Large Hadron Collider (LHC). However, the requirements to handle high-intensity beams can be demanding, and accident scenarios must be well studied in order to assess if the collimator design is robust against possible error scenarios. One of the catastrophic, though not very probable, accident scenarios identified within the LHC is an asynchronous beam dump. In this case, one (or more) of the 15 precharged kicker circuits fires out of time with the abort gap, spraying beam pulses onto LHC machine elements before the machine protection system can fire the remaining kicker circuits and bring the beam to the dump. If a proton bunch directly hits a collimator during such an event, severe beam-induced damage such as magnet quenches and other equipment damage might result, with consequent downtime for the machine. This study investigates a number of newly defined jaw error cases, which include angular misalignment errors of the collimator jaw. A numerical finite element method approach is presented in order to precisely evaluate the thermomechanical response of tertiary collimators to beam impact. We identify the most critical and interesting cases, and show that a tilt of the jaw can actually mitigate the effect of an asynchronous dump on the collimators. Relevant collimator damage limits are taken into account, with the aim to identify optimal operational conditions for the LHC. |
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Address |
[Cauchi, Marija; Assmann, R. W.; Bertarelli, A.; Carra, F.; Lari, L.; Rossi, A.] CERN, Geneva, Switzerland, Email: marija.cauchi@cern.ch |
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Amer Physical Soc |
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English |
Summary Language |
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ISSN |
1098-4402 |
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Notes |
WOS:000352074600002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2178 |
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Author |
Celis, A.; Fuentes-Martin, J.; Jung, M.; Serodio, H. |
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Title |
Family nonuniversal Z ' models with protected flavor-changing interactions |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
92 |
Issue |
1 |
Pages |
015007 - 17pp |
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Keywords |
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Abstract |
We define a new class of Z' models with neutral flavor-changing interactions at tree level in the down-quark sector. They are related in an exact way to elements of the quark mixing matrix due to an underlying flavored U(1)' gauge symmetry, rendering these models particularly predictive. The same symmetry implies lepton-flavor nonuniversal couplings, fully determined by the gauge structure of the model. Our models allow us to address presently observed deviations from the standard model and specific correlations among the new physics contributions to the Wilson coefficients C-9, 10((')l) can be tested in b -> sl(+)l(-) transitions. We furthermore predict lepton-universality violations in Z' decays, testable at the LHC. |
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Address |
[Celis, Alejandro] Univ Munich, Fak Phys, Arnold Sommerfeld Ctr Theoret Phys, D-80333 Munich, Germany, Email: alejandro.celis@physik.uni-muenchen.de; |
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Amer Physical Soc |
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English |
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ISSN |
1550-7998 |
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Notes |
WOS:000357859300004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2341 |
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Author |
Celis, A.; Fuentes-Martin, J.; Serodio, H. |
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Title |
An invisible axion model with controlled FCNCs at tree level |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
741 |
Issue |
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Pages |
117-123 |
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Keywords |
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Abstract |
We derive the necessary conditions to build a class of invisible axion models with Flavor Changing Neutral Currents at tree-level controlled by the fermion mixing matrices and present an explicit model implementation. A horizontal Peccei-Quinn symmetry provides a solution to the strong CP problem via the Peccei-Quinn mechanism and predicts a cold dark mater candidate, the invisible axion or familon. The smallness of active neutrino masses can be explained via a type I seesaw mechanism, providing a dynamical origin for the heavy seesaw scale. The possibility to avoid the domain wall problem stands as one of the most interesting features of the type of models considered. Experimental limits relying on the axion-photon coupling, astrophysical considerations and familon searches in rare kaon and muon decays are discussed. |
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Address |
[Celis, Alejandro; Fuentes-Martin, Javier; Serodio, Hugo] Univ Valencia, CSIC, Dept Fis Teor, E-46100 Burjassot, Spain, Email: alejandro.celis@ific.uv.es; |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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English |
Summary Language |
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Edition |
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ISSN |
0370-2693 |
ISBN |
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Notes |
WOS:000348290800016 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2108 |
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Author |
Chachamis, G.; Deak, M.; Hentschinski, M.; Rodrigo, G.; Sabio Vera, A. |
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Title |
Single bottom quark production in kT-factorisation |
Type |
Journal Article |
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Year |
2015 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
09 |
Issue |
9 |
Pages |
123 - 17pp |
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Keywords |
QCD Phenomenology; NLO Computations |
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Abstract |
We present a study within the k(T)-factorisation scheme on single bottom quark production at the LHC. In particular, we calculate the rapidity and transverse momentum differential distributions for single bottom quark/anti-quark production. In our setup, the unintegrated gluon density is obtained from the NLx BFKL Green function whereas we included mass effects to the Lx heavy quark jet vertex. We compare our results to the corresponding distributions predicted by the usual collinear factorisation scheme. The latter were produced with Pythia 8.1. |
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Address |
[Chachamis, Grigorios; Sabio Vera, Agustin] Univ Autonoma Madrid, E-28049 Madrid, Spain, Email: grigorios.chachamis@csic.es; |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1029-8479 |
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Medium |
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Conference |
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Notes |
WOS:000361753300003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2614 |
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