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Author Cabello, J.; Torres-Espallardo, I.; Gillam, J.E.; Rafecas, M.
Title PET Reconstruction From Truncated Projections Using Total-Variation Regularization for Hadron Therapy Monitoring Type Journal Article
Year 2013 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.
Volume 60 Issue 5 Pages 3364-3372
Keywords
Abstract (up) Hadron therapy exploits the properties of ion beams to treat tumors by maximizing the dose released to the target and sparing healthy tissue. With hadron beams, the dose distribution shows a relatively low entrance dose which rises sharply at the end of the range, providing the characteristic Bragg peak that drops quickly thereafter. It is of critical importance in order not to damage surrounding healthy tissues and/or avoid targeting underdosage to know where the delivered dose profile ends-the location of the Bragg peak. During hadron therapy, short-lived beta(+)-emitters are produced along the beam path, their distribution being correlated with the delivered dose. Following positron annihilation, two photons are emitted, which can be detected using a positron emission tomography (PET) scanner. The low yield of emitters, their short half-life, and the wash out from the target region make the use of PET, even only a few minutes after hadron irradiation, a challenging application. In-beam PET represents a potential candidate to estimate the distribution of beta(+)-emitters during or immediately after irradiation, at the cost of truncation effects and degraded image quality due to the partial rings required of the PET scanner. Time-of-flight (ToF) information can potentially be used to compensate for truncation effects and to enhance image contrast. However, the highly demanding timing performance required in ToF-PET makes this option costly. Alternatively, the use of maximum-a-posteriori-expectation-maximization (MAP-EM), including total variation (TV) in the cost function, produces images with low noise, while preserving spatial resolution. In this paper, we compare data reconstructed with maximum-likelihood-expectation-maximization (ML-EM) and MAP-EM using TV as prior, and the impact of including ToF information, from data acquired with a complete and a partial-ring PET scanner, of simulated hadron beams interacting with a polymethyl methacrylate (PMMA) target. The results show that MAP-EM, in the absence of ToF information, produces lower noise images and more similar data compared to the simulated beta(+) distributions than ML-EM with ToF information in the order of 200-600 ps. The investigation is extended to the combination of MAP-EM and ToF information to study the limit of performance using both approaches.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0018-9499 ISBN Medium
Area Expedition Conference
Notes WOS:000325827200023 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1610
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Author Bouhova-Thacker, E.; Kostyukhin, V.; Koffas, T.; Liebig, W.; Limper, M.; Piacquadio, G.N.; Prokofiev, K.; Weiser, C.; Wildauer, A.
Title Expected Performance of Vertex Reconstruction in the ATLAS Experiment at the LHC Type Journal Article
Year 2010 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.
Volume 57 Issue 2 Pages 760-767
Keywords Data analysis; data reconstruction; high energy physics; pattern recognition; reconstruction algorithms; tracking; vertex detectors
Abstract (up) In the harsh environment of the Large Hadron Collider at CERN (design luminosity of 10(34) cm(-2) s(-1)) efficient reconstruction of vertices is crucial for many physics analyses. Described in this paper is the expected performance of the vertex reconstruction used in the ATLAS experiment. The algorithms for the reconstruction of primary and secondary vertices as well as for finding photon conversions and vertex reconstruction in jets are described. The implementation of vertex algorithms which follows a very modular design based on object-oriented C++ is presented. A user-friendly concept allows event reconstruction and physics analyses to compare and optimize their choice among different vertex reconstruction strategies. The performance of implemented algorithms has been studied on a variety of Monte Carlo samples and results are presented.
Address [Bouhova-Thacker, Eva] Univ Lancaster, Lancaster LA1 4YB, England, Email: bouhova@mail.cern.ch
Corporate Author Thesis
Publisher Ieee-Inst Electrical Electronics Engineers Inc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0018-9499 ISBN Medium
Area Expedition Conference
Notes ISI:000276679200006 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 260
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Author Boronat, M.; Marinas, C.; Frey, A.; Garcia, I.; Schwenker, B.; Vos, M.; Wilk, F.
Title Physical Limitations to the Spatial Resolution of Solid-State Detectors Type Journal Article
Year 2015 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.
Volume 62 Issue 1 Pages 381-386
Keywords Charged particle tracking; silicon detectors; solid state devices
Abstract (up) In this paper we explore the effect of delta-ray emission and fluctuations in the signal deposition on the detection of charged particles in silicon-based detectors. We show that these two effects ultimately limit the resolution that can be achieved by interpolation of the signal in finely segmented position-sensitive solid-state devices.
Address [Boronat, M.; Garcia, I.; Vos, M.] IFIC UVEG CSIC, E-46980 Valencia, Spain, Email: marcel.vos@ific.uv.es
Corporate Author Thesis
Publisher Ieee-Inst Electrical Electronics Engineers Inc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0018-9499 ISBN Medium
Area Expedition Conference
Notes WOS:000349672900025 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 2140
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Author Barrientos, D.; Bellato, M.; Bazzacco, D.; Bortolato, D.; Cocconi, P.; Gadea, A.; Gonzalez, V.; Gulmini, M.; Isocrate, R.; Mengoni, D.; Pullia, A.; Recchia, F.; Rosso, D.; Sanchis, E.; Toniolo, N.; Ur, C.A.; Valiente-Dobon, J.J.
Title Performance of the Fully Digital FPGA-Based Front-End Electronics for the GALILEO Array Type Journal Article
Year 2015 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.
Volume 62 Issue 6 Pages 3134-3139
Keywords FPGA; front-end electronics; gamma-ray spectroscopy; germanium detectors
Abstract (up) In this work we present the architecture and results of a fully digital Front End Electronics (FEE) read out system developed for the GALILEO array. The FEE system, developed in collaboration with the Advanced Gamma Tracking Array (AGATA) collaboration, is composed of three main blocks: preamplifiers, digitizers and preprocessing electronics. The slow control system contains a custom Linux driver, a dynamic library and a server implementing network services. This work presents the first results of the digital FEE system coupled with a GALILEO germanium detector, which has demonstrated the capability to achieve an energy resolution of 1.53% at an energy of 1.33 MeV, similar to the one obtained with a conventional analog system. While keeping a good performance in terms of energy resolution, digital electronics will allow to instrument the full GALILEO array with a versatile system with high integration and low power consumption and costs.
Address [Barrientos, D.; Bortolato, D.; Cocconi, P.; Gulmini, M.; Rosso, D.; Toniolo, N.; Valiente-Dobon, J. J.] Ist Nazl Fis Nucl, Lab Nazl Legnaro, I-35020 Padua, Italy, Email: diego.barrientos@lnl.infn.it
Corporate Author Thesis
Publisher Ieee-Inst Electrical Electronics Engineers Inc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0018-9499 ISBN Medium
Area Expedition Conference
Notes WOS:000372013500005 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 2612
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Author Barrientos, D.; Gonzalez, V.; Bellato, M.; Gadea, A.; Bazzacco, D.; Blasco, J.M.; Bortolato, D.; Egea, F.J.; Isocrate, R.; Pullia, A.; Rampazzo, G.; Sanchis, E.; Triossi, A.
Title Multiple Register Synchronization With a High-Speed Serial Link Using the Aurora Protocol Type Journal Article
Year 2013 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.
Volume 60 Issue 5 Pages 3521-3525
Keywords
Abstract (up) In this work, the development and characterization of a multiple synchronous registers interface communicating with a high-speed serial link and using the Aurora protocol is presented. A detailed description of the developing process and the characterization methods and hardware test benches are also included. This interface will implement the slow control buses of the digitizer cards for the second generation of electronics for the Advanced GAmma Tracking Array (AGATA).
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0018-9499 ISBN Medium
Area Expedition Conference
Notes WOS:000325827700014 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1612
Permanent link to this record