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Author |
Chen, M.C.; Li, X.Q.; Liu, X.G.; Medina, O.; Ratz, M. |
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Title |
Modular invariant holomorphic observables |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
852 |
Issue |
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Pages |
138600 - 13pp |
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Abstract  |
In modular invariant models of flavor, observables must be modular invariant. The observables discussed so far in the literature are functions of the modulus tau and its conjugate, (tau) over bar. We point out that certain combinations of observables depend only on tau , i.e. are meromorphic, and in some cases even holomorphic functions of tau. These functions, which we dub “invariants” in this Letter, are highly constrained, renormalization group invariant, and allow us to derive many of the models' features without the need for extensive parameter scans. We illustrate the robustness of these invariants in two existing models in the literature based on modular symmetries, Gamma(3) and Gamma(5). We find that, in some cases, the invariants give rise to robust relations among physical observables that are independent of tau. Furthermore, there are instances where additional symmetries exist among the invariants. These symmetries are relevant phenomenologically and may provide a dynamical way to realize symmetries of mass matrices. |
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Address |
[Chen, Mu-Chun; Li, Xueqi; Liu, Xiang-Gan; Ratz, Michael] Univ Calif Irvine, Dept Phys & Astron, Irvine, CA 92697 USA, Email: muchunc@uci.edu; |
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Elsevier |
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English |
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0370-2693 |
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WOS:001221253800001 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6125 |
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Author |
Di Gregorio, E.; Staelens, M.; Hosseinkhah, N.; Karimpoor, M.; Liburd, J.; Lim, L.; Shankar, K.; Tuszynski, J.A. |
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Title |
Raman Spectroscopy Reveals Photobiomodulation-Induced α-Helix to β-Sheet Transition in Tubulins: Potential Implications for Alzheimer's and Other Neurodegenerative Diseases |
Type |
Journal Article |
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Year |
2024 |
Publication |
Nanomaterials |
Abbreviated Journal |
Nanomaterials |
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Volume |
14 |
Issue |
13 |
Pages |
1093 - 21pp |
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Keywords |
proteins; protein dynamics; protein structure; non-invasive therapies; low-level laser therapy; spectroscopy; amide bands; amide I; spectral decomposition |
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Abstract |
In small clinical studies, the application of transcranial photobiomodulation (PBM), which typically delivers low-intensity near-infrared (NIR) to treat the brain, has led to some remarkable results in the treatment of dementia and several neurodegenerative diseases. However, despite the extensive literature detailing the mechanisms of action underlying PBM outcomes, the specific mechanisms affecting neurodegenerative diseases are not entirely clear. While large clinical trials are warranted to validate these findings, evidence of the mechanisms can explain and thus provide credible support for PBM as a potential treatment for these diseases. Tubulin and its polymerized state of microtubules have been known to play important roles in the pathology of Alzheimer's and other neurodegenerative diseases. Thus, we investigated the effects of PBM on these cellular structures in the quest for insights into the underlying therapeutic mechanisms. In this study, we employed a Raman spectroscopic analysis of the amide I band of polymerized samples of tubulin exposed to pulsed low-intensity NIR radiation (810 nm, 10 Hz, 22.5 J/cm2 dose). Peaks in the Raman fingerprint region (300-1900 cm-1)-in particular, in the amide I band (1600-1700 cm-1)-were used to quantify the percentage of protein secondary structures. Under this band, hidden signals of C=O stretching, belonging to different structures, are superimposed, producing a complex signal as a result. An accurate decomposition of the amide I band is therefore required for the reliable analysis of the conformation of proteins, which we achieved through a straightforward method employing a Voigt profile. This approach was validated through secondary structure analyses of unexposed control samples, for which comparisons with other values available in the literature could be conducted. Subsequently, using this validated method, we present novel findings of statistically significant alterations in the secondary structures of polymerized NIR-exposed tubulin, characterized by a notable decrease in alpha-helix content and a concurrent increase in beta-sheets compared to the control samples. This PBM-induced alpha-helix to beta-sheet transition connects to reduced microtubule stability and the introduction of dynamism to allow for the remodeling and, consequently, refreshing of microtubule structures. This newly discovered mechanism could have implications for reducing the risks associated with brain aging, including neurodegenerative diseases like Alzheimer's disease, through the introduction of an intervention following this transition. |
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Address |
[Di Gregorio, Elisabetta; Staelens, Michael; Tuszynski, Jack A.] Univ Alberta, Fac Sci, Dept Phys, Edmonton, AB T6G 2E1, Canada, Email: michael.staelens@ific.uv.es |
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Mdpi |
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English |
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Notes |
WOS:001269841000001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6204 |
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Author |
Beltran, R.; Günther, J.; Hirsch, M.; Titov, A.; Wang, Z.S. |
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Title |
Heavy neutral leptons from kaons in effective field theory |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
109 |
Issue |
11 |
Pages |
115014 - 19pp |
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Abstract |
In the framework of the low -energy effective theory containing, in addition to the Standard -Model fields, heavy neutral leptons (HNLs), we compute the decay rates of neutral and charged kaons into HNLs. We consider both lepton -number -conserving and lepton -number -violating four-fermion operators, taking into account also the contribution of active -heavy neutrino mixing. Assuming that the produced HNLs are longlived, we perform simulations and calculate the sensitivities of future long -lived -particle (LLP) detectors at the high -luminosity LHC as well as the near detector of the Deep Underground Neutrino Experiment (DUNE -ND) to the considered scenario. When applicable, we also recast the existing bounds on the minimal mixing case obtained by NA62, T2K, and PS191. Our findings show that, while the future LHC LLP detectors can probe currently allowed parameter space only in certain benchmark scenarios, DUNE -ND should be sensitive to parameter space beyond the current bounds in almost all the benchmark scenarios, and, for some of the effective operators considered, it can even probe new -physics scales in excess of 3000 TeV. |
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Address |
[Beltran, Rebeca; Hirsch, Martin] Univ Valencia, CSIC, AHEP Grp, Inst Fis Corpuscular, Apartado 22085, E-46071 Valencia, Spain, Email: rebeca.beltran@ific.uv.es; |
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Amer Physical Soc |
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English |
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2470-0010 |
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Notes |
WOS:001250419300003 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6165 |
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Author |
Fernandez Navarro, M.; King, S.F.; Vicente, A. |
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Title |
Tri-unification: a separate SU(5) for each fermion family |
Type |
Journal Article |
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Year |
2024 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
05 |
Issue |
5 |
Pages |
130 - 32pp |
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Keywords |
Grand Unification; Theories of Flavour |
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Abstract |
In this paper we discuss SU(5)3 with cyclic symmetry as a possible grand unified theory (GUT). The basic idea of such a tri-unification is that there is a separate SU(5) for each fermion family, with the light Higgs doublet(s) arising from the third family SU(5), providing a basis for charged fermion mass hierarchies. SU(5)3 tri-unification reconciles the idea of gauge non-universality with the idea of gauge coupling unification, opening the possibility to build consistent non-universal descriptions of Nature that are valid all the way up to the scale of grand unification. As a concrete example, we propose a grand unified embedding of the tri-hypercharge model \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\text{U}}{\left(1\right)}_{Y}<^>{3}$$\end{document} based on an SU(5)3 framework with cyclic symmetry. We discuss a minimal tri-hypercharge example which can account for all the quark and lepton (including neutrino) masses and mixing parameters. We show that it is possible to unify the many gauge couplings into a single gauge coupling associated with the cyclic SU(5)3 gauge group, by assuming minimal multiplet splitting, together with a set of relatively light colour octet scalars. We also study proton decay in this example, and present the predictions for the proton lifetime in the dominant e+pi 0 channel. |
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Address |
[Navarro, Mario Fernandez; King, Stephen F.] Univ Southampton, Sch Phys & Astron, Southampton SO17 1BJ, England, Email: Mario.FernandezNavarro@glasgow.ac.uk; |
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Springer |
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English |
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ISSN |
1029-8479 |
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Notes |
WOS:001256025400004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6171 |
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Author |
Li, H.P.; Song, J.; Liang, W.H.; Molina, R.; Oset, E. |
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Title |
Contrasting observables related to the N*(1535) from the molecular or a genuine structure |
Type |
Journal Article |
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Year |
2024 |
Publication |
European Physical Journal C |
Abbreviated Journal |
Eur. Phys. J. C |
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Volume |
84 |
Issue |
7 |
Pages |
656 - 8pp |
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Abstract |
In this work we compare the predictions for the scattering length and effective range of the channels K-0 Sigma(+), K+Sigma(0), K+ Lambda and eta p, assuming the N*(1535) state as a molecular state of these channels, or an original genuine state, made for instance from three quarks. Looking at very different scenarios, what we conclude is that the predictions of these two pictures are drastically different, to the point that we advise the measurement of these magnitudes, accessible for instance by measuring correlation functions, in order to gain much valuable information concerning the nature of this state. |
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Address |
[Li, Hai-Peng; Liang, Wei-Hong; Molina, R.; Oset, E.] Guangxi Normal Univ, Dept Phys, Guilin 541004, Peoples R China, Email: Song-Jing@buaa.edu.cn; |
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Springer |
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English |
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ISSN |
1434-6044 |
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Notes |
WOS:001261436900002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6186 |
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Author |
Heidari, N.; Hassanabadi, H.; Araujo, A.A.; Kriz, J. |
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Title |
Exploring non-commutativity as a perturbation in the Schwarzschild black hole: quasinormal modes, scattering, and shadows |
Type |
Journal Article |
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Year |
2024 |
Publication |
European Physical Journal C |
Abbreviated Journal |
Eur. Phys. J. C |
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Volume |
84 |
Issue |
6 |
Pages |
566 - 11pp |
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Abstract |
In this work, by a novel approach to studying the scattering of a Schwarzschild black hole, the non-commutativity is introduced as perturbation. We begin by reformulating the Klein-Gordon equation for the scalar field in a new form that takes into account the deformed non-commutative spacetime. Using this formulation, an effective potential for the scattering process is derived. To calculate the quasinormal modes, we employ the WKB method and also utilize fitting techniques to investigate the impact of non-commutativity on the scalar quasinormal modes. We thoroughly analyze the results obtained from these different methods. Moreover, the greybody factor and absorption cross section are investigated. Additionally, we explore the behavior of null geodesics in the presence of non-commutativity. Specifically, we examine the photonic, and shadow radius as well as the light trajectories for different non-commutative parameters. Therefore, by addressing these various aspects, we aim to provide a comprehensive understanding of the influence of non-commutativity on the scattering of a Schwarzschild-like black hole and its implications for the behavior of scalar fields and light trajectories. |
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Address |
[Heidari, N.; Hassanabadi, H.] Shahrood Univ Technol, Fac Phys, Shahrood, Iran, Email: heidari.n@gmail.com |
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Springer |
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English |
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ISSN |
1434-6044 |
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Conference |
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Notes |
WOS:001239390500007 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6191 |
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Author |
Das, B. et al; Algora, A. |
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Title |
Broken seniority symmetry in the semimagic proton mid-shell nucleus 95Rh |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physical Review Research |
Abbreviated Journal |
Phys. Rev. Res. |
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Volume |
6 |
Issue |
2 |
Pages |
L022038 - 7pp |
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Keywords |
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Abstract |
Lifetime measurements of low-lying excited states in the semimagic ( N = 50) nucleus 95 Rh have been performed by means of the fast -timing technique. The experiment was carried out using gamma -ray detector arrays consisting of LaBr 3 (Ce) scintillators and germanium detectors integrated into the DESPEC experimental setup commissioned for the Facility for Antiproton and Ion Research ( FAIR ) Phase -0, Darmstadt, Germany. The excited states in 95 Rh were populated primarily via the /3 decays of 95 Pd nuclei, produced in the projectile fragmentation of a 850 MeV / nucleon 124 Xe beam impinging on a 4 g / cm 2 9 Be target. The deduced electromagnetic E2 transition strengths for the gamma -ray cascade within the multiplet structure depopulating from the isomeric I pi = 21 / 2 + state are found to exhibit strong deviations from predictions of standard shell model calculations which feature approximately conserved seniority symmetry. In particular, the observation of a strongly suppressed E2 strength for the 13 / 2 + -> 9 / 2 + ground state transition cannot be explained by calculations employing standard interactions. This remarkable result may require revision of the nucleon-nucleon interactions employed in state-of-the-art theoretical model calculations, and might also point to the need for including three-body forces in the Hamiltonian. |
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Address |
[Das, B.; Cederwall, B.; Qi, C.; Aktas, O.; Liotta, R.; Vasiljevic, J.] KTH Royal Inst Technol, S-10691 Stockholm, Sweden, Email: b.das@gsi.de; |
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Amer Physical Soc |
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English |
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Notes |
WOS:001240855200002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6147 |
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Author |
ATLAS Collaboration (Aad, G. et al); Amos, K.R.; Aparisi Pozo, J.A.; Bailey, A.J.; Cabrera Urban, S.; Cantero, J.; Cardillo, F.; Castillo Gimenez, V.; Costa, M.J.; Didenko, M.; Escobar, C.; Fiorini, L.; Fullana Torregrosa, E.; Fuster, J.; Garcia, C.; Garcia Navarro, J.E.; Gomez Delegido, A.J.; Gonzalez de la Hoz, S.; Gonzalvo Rodriguez, G.R.; Guerrero Rojas, J.G.R.; Lacasta, C.; Marti-Garcia, S.; Martinez Agullo, P.; Miralles Lopez, M.; Mitsou, V.A.; Monsonis Romero, L.; Moreno Llacer, M.; Munoz Perez, D.; Navarro-Gonzalez, J.; Poveda, J.; Prades Ibañez, A.; Rubio Jimenez, A.; Ruiz-Martinez, A.; Sabatini, P.; Salt, J.; Sanchez Sebastian, V.; Sayago Galvan, I.; Senthilkumar, V.; Soldevila, U.; Sanchez, J.; Torro Pastor, E.; Valero, A.; Valiente Moreno, E.; Valls Ferrer, J.A.; Varriale, L.; Villaplana Perez, M.; Vos, M. |
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Title |
Measurements of the suppression and correlations of dijets in Xe+Xe collisions at √s NN=5.44 TeV |
Type |
Journal Article |
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Year |
2023 |
Publication |
Physical Review C |
Abbreviated Journal |
Phys. Rev. C |
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Volume |
108 |
Issue |
2 |
Pages |
024906 - 25pp |
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Keywords |
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Abstract |
Measurements of the suppression and correlations of dijets is performed using 3 μb(-1) of Xe+Xe data at root sNN = 5.44 TeV collected with the ATLAS detector at the CERN Large Hadron Collider. Dijets with jets reconstructed using the R = 0.4 anti-kt algorithm are measured differentially in jet p(T) over the range of 32 to 398 GeV and the centrality of the collisions. Significant dijet momentum imbalance is found in the most central Xe+Xe collisions, which decreases in more peripheral collisions. Results from the measurement of per-pair normalized and absolutely normalized dijet p(T) balance are compared with previous Pb+Pb measurements at root sNN = 5.02 TeV. The differences between the dijet suppression in Xe+Xe and Pb+Pb are further quantified by the ratio of pair nuclear-modification factors. The results are found to be consistent with those measured in Pb+Pb data when compared in classes of the same event activity and when taking into account the difference between the center-of-mass energies of the initial parton scattering process in Xe+Xe and Pb+Pb collisions. These results should provide input for a better understanding of the role of energy density, system size, path length, and fluctuations in the parton energy loss. |
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Address |
[Fedin, O. L.; Filmer, E. K.; Huseynov, N.; Jackson, P.; Kong, A. X. Y.; Myagkov, A. G.; Nikolaenko, V.; Potti, H.; Ruggeri, T. A.; Ting, E. X. L.; White, M. J.] Univ Adelaide, Dept Phys, Adelaide, SA, Australia |
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Amer Physical Soc |
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English |
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ISSN |
2469-9985 |
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Notes |
WOS:001256732300001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6215 |
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Author |
Martins, A.; da Mota, A.F.; Stanford, C.; Contreras, T.; Martin-Albo, J.; Kish, A.; Escobar, C.O.; Para, A.; Guenette, R. |
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Title |
Simple strategy for the simulation of axially symmetric large-area metasurfaces |
Type |
Journal Article |
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Year |
2024 |
Publication |
Journal of the Optical Society of America B |
Abbreviated Journal |
J. Opt. Soc. Am. B |
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Volume |
41 |
Issue |
5 |
Pages |
1261-1269 |
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Abstract |
Metalenses are composed of nanostructures for focusing light and have been widely explored in many exciting applications. However, their expanding dimensions pose simulation challenges. We propose a method to simulate metalenses in a timely manner using vectorial wave and ray tracing models. We sample the metalens's radial phase gradient and locally approximate the phase profile by a linear phase response. Each sampling point is modeled as a binary blazed grating, employing the chosen nanostructure, to build a transfer function set. The metalens transmission or reflection is then obtained by applying the corresponding transfer function to the incoming field on the regions surrounding each sampling point. Fourier optics is used to calculate the scattered fields under arbitrary illumination for the vectorial wave method, and a Monte Carlo algorithm is used in the ray tracing formalism. We validated our method against finite -difference time domain simulations at 632 nm, and we were able to simulate metalenses larger than 3000 wavelengths in diameter on a personal computer. |
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Address |
[Martins, Augusto; Guenette, Roxanne] Univ Manchester, Dept Phys, Manchester M13 9PL, England, Email: augusto.martins@york.ac.uk |
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Optica Publishing Group |
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English |
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ISSN |
0740-3224 |
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Notes |
WOS:001237140900001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6140 |
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Author |
Penas, J.; Alejo, A.; Bembibre, A.; Apiñaniz, J.I.; Garcia-Garcia, E.; Guerrero, C.; Henares, J.L.; Hernandez-Palmero, I.; Mendez, C.; Millan-Callado, M.A.; Puyuelo-Valdes, P.; Seimetz, M.; Benlliure, J. |
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Title |
Production of carbon-11 for PET preclinical imaging using a high-repetition rate laser-driven proton source |
Type |
Journal Article |
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Year |
2024 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
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Volume |
14 |
Issue |
1 |
Pages |
11448 - 12pp |
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Abstract |
Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range. |
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Address |
[Penas, Juan; Alejo, Aaron; Bembibre, Adrian; Benlliure, Jose] Univ Santiago de Compostela, Inst Galego Fis Altas Enerxias IGFAE, Santiago De Compostela 15782, Spain, Email: j.benlliure@usc.es |
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Publisher |
Nature Portfolio |
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Language |
English |
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ISSN |
2045-2322 |
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Notes |
WOS:001228252900017 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
6143 |
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