Abstract: We report on a hybrid in-beam PET and prompt-gamma Compton imaging system aimed at quasi real-time ion-range verification in proton-therapy treatments. Proof-of-concept experiments were carried out at the radiobiology beam line of the CNA cyclotron facility using a set of two synchronous Compton imagers and different target materials. The time structure of the 18 MeV proton beam was shaped with a series of beam-on and beam-off intervals, thereby mimicking a pulsed proton beam on a long time scale. During beam-on intervals, Compton imagingwas performed utilizing the high energy. -rays promptly emitted from the nuclear reactions occurring in the targets. In the course of the beam-off intervals in situ positron-emission tomography was accomplished with the same imagers using the beta+ decay of activated nuclei. The targets used were stacks of different materials covering also various proton ranges and energies. A systematic study on the performance of these two complementary imaging techniques is reported and the experimental results interpreted on the basis ofMonte Carlo calculations. The results demonstrate the possibility to combine both imaging techniques in a concomitant way, where high-efficiency prompt-gamma imaging is complemented with the high spatial accuracy of PET. Empowered by these results we suggest that a pulsed beam with a suitable duty cycle, in conjunction with in situ Compton- and PET-imaging may help to attain complementary information and quasi real-time range monitoring with high accuracy.

Abstract: We report new measurements of the drift velocity and longitudinal diffusion coefficients of electrons in pure xenon gas and in xenon-helium gas mixtures at 1-9 bar and electric field strengths of 50-300 V/cm. In pure xenon we find excellent agreement with world data at all E/P, for both drift velocity and diffusion coefficients. However, a larger value of the longitudinal diffusion coefficient than theoretical predictions is found at low E/P in pure xenon, below the range of reduced fields usually probed by TPC experiments. A similar effect is observed in xenon-helium gas mixtures at somewhat larger E/P. Drift velocities in xenon-helium mixtures are found to be theoretically well predicted. Although longitudinal diffusion in xenon-helium mixtures is found to be larger than anticipated, extrapolation based on the measured longitudinal diffusion coefficients suggest that the use of helium additives to reduce transverse diffusion in xenon gas remains a promising prospect.

Abstract: We report measurements of the flux-integrated (nu) over bar (mu) and (nu) over bar (mu) + nu(mu) charged-current cross -sections on water and hydrocarbon targets using the T2K anti-neutrino beam with a mean beam energy of 0.86 GeV. The signal is defined as the (anti -)neutrino charged-current interaction with one induced mu(+/-) and no detected charged pion or proton. These measurements are performed using a new WAGASCI module recently added to the T2K setup in combination with the INGRID Proton Module. The phase space of muons is restricted to the high-detection efficiency region, p(mu) > 400 MeV/c and theta(mu) < 30 degrees, in the laboratory frame. An absence of pions and protons in the detectable phase spaces of p(pi) > 200 MeV/c, theta(pi) < 70 degrees and p(p) > 600 MeV/c, theta(p) < 70 degrees is required. In this paper, both the <(nu)over bar>(mu), cross-sections and (nu) over bar (mu) + nu(mu), cross-sections on water and hydrocarbon targets and their ratios are provided by using the D'Agostini unfolding method. The results of the integrated (nu) over bar (mu), cross-section measurements over this phase space are sigma(H2O) = (1.082 +/- 0.068(stat.)(+0.145)(-0.128)(syst.)) x 10(-39) cm(2)/nucleon, sigma(CH) = (1.096 +/- 0.054 (stat.)(+0.132)(-0.117)(syst.)) x 10(-39) cm(2) /nucleon, and sigma(H2O)/sigma(CH) = 0.987 +/- 0.078 (stat.)(+0.093)(-0.090)(syst.). The (nu) over bar (mu), + nu(mu), cross-section is sigma(H2O) = (1.155 +/- 0.064(stat.)(+0.148)(-0.129)(syst.)) x 10(-39) cm(2)/nucleon, sigma(CH) = (1.159 +/- 0.049(stat.)(+0.129)(-0.115)(syst.)) x 10(-39) cm(2)/nucleon, and sigma(H2O)/sigma(CH) = 0.996 +/- 0.069(stat.)(+0.083)(-0.078)(syst.).

Abstract: We report measurements by the T2K experiment of the parameters theta(23) and Delta m(32)(2), which govern the disappearance of muon neutrinos and antineutrinos in the three-flavor PMNS neutrino oscillation model at T2K's neutrino energy and propagation distance. Utilizing the ability of the experiment to run with either a mainly neutrino or a mainly antineutrino beam, muon-like events from each beam mode are used to measure these parameters separately for neutrino and antineutrino oscillations. Data taken from 1.49 x 10(21) protons on target (POT) in neutrino mode and 1.64 x 10(21) POT in antineutrino mode are used. The best-fit values obtained by T2K were sin(2)(theta(23)) = 0.51(-0.07)(+0.06) (0.43(-0.05)(+0.21)) and Delta m(32)(2) = 2.47(-0.09)(+0.08) (2.50(-0.13)(+0.18)) x 10(-3) eV(2)/c(4) for neutrinos (antineutrinos). No significant differences between the values of the parameters describing the disappearance of muon neutrinos and antineutrinos were observed. An analysis using an effective two-flavor neutrino oscillation model where the sine of the mixing angle is allowed to take nonphysical values larger than 1 is also performed to check the consistency of our data with the three-flavor model. Our data were found to be consistent with a physical value for the mixing angle.

Abstract: We report four narrow peaks in the Xi K-0(b)- mass spectrum obtained using pp collisions at center-of-mass energies of 7, 8, and 13 TeV, corresponding to a total integrated luminosity of 9 fb(-1) recorded by the LHCb experiment. Referring to these states by their mass, the mass values are m[Omega(b)(6316)(-)] = 6315.64 +/- 0.31 +/- 0.07 +/- 0.50 MeV, m[Omega(b)(6330)(-)] = 6330.30 +/- 0.28 +/- 0.07 +/- 0.50 MeV, m[Omega(b)(6340)(-)] = 6339.71 +/- 0.26 +/- 0.05 +/- 0.50 MeV, m[Omega(b)(6350)(-)] = 6349.88 +/- 0.35 +/- 0.05 +/- 0.50 MeV, where the uncertainties are statistical, systematic, and the last is due to the knowledge of the Xi(0)(b) mass. The natural widths of the three lower mass states are consistent with zero, and the 90% confidence-level upper limits are determined to be Gamma[Omega(b)(6316)(-)] < 2.8 MeV, Gamma[Omega(b)(6330)(-)] < 3.1 MeV and Gamma[Omega(b)(6340)-] < 1.5 MeV. The natural width of the Omega(b)(6350)(-) peak is 1.4(-0.8)(+1.0) +/- 0.1 MeV, which is 2.5 sigma from zero and corresponds to an upper limit of 2.8 MeV. The peaks have local significances ranging from 3.6 sigma to 7.2 sigma. After accounting for the look-elsewhere effect, the significances of the Omega(b)(6316)(-) and Omega(b)(6330)(-) peaks are reduced to 2.1 sigma and 2.6 sigma, respectively, while the two higher mass peaks exceed 5 sigma. The observed peaks are consistent with expectations for excited Omega(-)(b) resonances.