Records |
Author |
Briz, J.A.; Nerio, A.N.; Ballesteros, C.; Borge, M.J.G.; Martinez, P.; Perea, A.; Tavora, V.G.; Tengblad, O.; Ciemala, M.; Maj, A.; Olko, P.; Parol, W.; Pedracka, A.; Sowicki, B.; Zieblinski, M.; Nacher, E. |
Title |
Proton Radiographs Using Position-Sensitive Silicon Detectors and High-Resolution Scintillators |
Type |
Journal Article |
Year |
2022 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
Volume |
69 |
Issue |
4 |
Pages |
696-702 |
Keywords |
LaBr3; particle tracking; proton computed tomography (pCT); proton radiograph; proton therapy; scintillation detectors; silicon detectors |
Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
Proton therapy is a cancer treatment technique currently in growth since it offers advantages with respect to conventional X-ray and gamma-ray radiotherapy. In particular, better control of the dose deposition allowing to reach higher conformity in the treatments causing less secondary effects. However, in order to take full advantage of its potential, improvements in treatment planning and dose verification are required. A new prototype of proton computed tomography scanner is proposed to design more accurate and precise treatment plans for proton therapy. Our prototype is formed by double-sided silicon strip detectors and scintillators of LaBr3(Ce) with high energy resolution and fast response. Here, the results obtained from an experiment performed using a 100-MeV proton beam are presented. Proton radiographs of polymethyl methacrylate (PMMA) samples of 50-mm thickness with spatial patterns in aluminum were taken. Their properties were studied, including reproduction of the dimensions, spatial resolution, and sensitivity to different materials. Structures of up to 2 mm are well resolved and the sensitivity of the system was enough to distinguish the thicknesses of 10 mm of aluminum or PMMA. The spatial resolution of the images was 0.3 line pairs per mm (MTF-10%). This constitutes the first step to validate the device as a proton radiography scanner. |
Address |
[Briz, J. A.; Nerio, A. N.; Ballesteros, C.; Borge, M. J. G.; Martinez, P.; Perea, A.; Tavora, V. G.; Tengblad, O.] Inst Estruct Mat CSIC, Madrid 28006, Spain, Email: jose.briz@csic.es |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
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English |
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Edition |
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ISSN |
0018-9499 |
ISBN |
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Medium |
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Expedition |
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Conference |
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Notes |
WOS:000803113800017 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
5245 |
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Author |
Oliver, J.F.; Fuster-Garcia, E.; Cabello, J.; Tortajada, S.; Rafecas, M. |
Title |
Application of Artificial Neural Network for Reducing Random Coincidences in PET |
Type |
Journal Article |
Year |
2013 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
Volume |
60 |
Issue |
5 |
Pages |
3399-3409 |
Keywords |
|
Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
Positron Emission Tomography (PET) is based on the detection in coincidence of the two photons created in a positron annihilation. In conventional PET, this coincidence identification is usually carried out through a coincidence electronic unit. An accidental coincidence occurs when two photons arising from different annihilations are classified as a coincidence. Accidental coincidences are one of the main sources of image degradation in PET. Some novel systems allow coincidences to be selected post-acquisition in software, or in real time through a digital coincidence engine in an FPGA. These approaches provide the user with extra flexibility in the sorting process and allow the application of alternative coincidence sorting procedures. In this work a novel sorting procedure based on Artificial Neural Network (ANN) techniques has been developed. It has been compared to a conventional coincidence sorting algorithm based on a time coincidence window. The data have been obtained from Monte-Carlo simulations. A small animal PET scanner has been implemented to this end. The efficiency (the ratio of correct identifications) can be selected for both methods. In one case by changing the actual value of the coincidence window used, and in the other by changing a threshold at the output of the neural network. At matched efficiencies, the ANN-based method always produces a sorted output with a smaller random fraction. In addition, two differential trends are found: the conventional method presents a maximum achievable efficiency, while the ANN-based method is able to increase the efficiency up to unity, the ideal value, at the cost of increasing the random fraction. Images reconstructed using ANN sorted data (no compensation for randoms) present better contrast, and those image features which are more affected by randoms are enhanced. For the image quality phantom used in the paper, the ANN method decreases the spill-over ratio by a factor of 18%. |
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ISSN |
0018-9499 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000325827200027 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
1611 |
Permanent link to this record |
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Author |
Real, D.; Calvo, D.; Diaz, A.; Alves Garre, S.; Carretero, V.; Sanchez Losa, A.; Salesa Greus, F. |
Title |
An Ultra-Narrow Time Optical Pulse Emitter Based on a Laser: UNTOPEL |
Type |
Journal Article |
Year |
2023 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
Volume |
70 |
Issue |
10 |
Pages |
2364-2372 |
Keywords |
Instrumentation electronics; neutrino telescope instrumentation; subnanosecond light source; time calibration instrument |
Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
Light sources that emit repetitive subnanosecond pulses are used in neutrino telescopes for time calibration. Optical pulses with an ultra-narrow (subnanosecond) width can replicate the light produced by neutrino interactions, and are an important calibration and test element. By measuring the time-of-flight of the light, it is possible to provide a relative time calibration for all the detector photomultipliers. This work presents the ultra-narrow time optical pulse emitter based on a laser (UNTOPEL), an instrument emitting ultra-short laser optical pulses with a duration of 500 ps, energies per pulse of four microjoules at a wavelength of 532 nm, and a timing precision of 400 ps. The UNTOPEL pulse intensity can be fine-tuned, which is a novelty and a significant advantage in those applications that need to illuminate light detectors located at different distances with the same light intensity. The UNTOPEL pulse intensity can be controlled remotely, allowing for its use in operating conditions where physical access is impossible or difficult. Moreover, it is easy to operate and can be easily controlled through an inter-integrated circuit bus. The UNTOPEL is a sound instrument used when subnanosecond pulses and variable energy emissions are needed. |
Address |
[Real, Diego; Calvo, David; Garre, Sergio Alves; Carretero, Victor; Losa, Agustin Sanchez; Greus, FranciscoSalesa] Univ Valencia, IFIC Inst Fis Corpuscular, CSIC, Paterna 46980, Spain, Email: real@ific.uv.es |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
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English |
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Edition |
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ISSN |
0018-9499 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001098078200010 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
no |
Call Number |
IFIC @ pastor @ |
Serial |
5795 |
Permanent link to this record |
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Author |
Brown, J.M.C.; Gillam, J.E.; Paganin, D.M.; Dimmock, M.R. |
Title |
Laplacian Erosion: An Image Deblurring Technique for Multi-Plane Gamma-Cameras |
Type |
Journal Article |
Year |
2013 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
Volume |
60 |
Issue |
5 |
Pages |
3333-3342 |
Keywords |
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Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
Laplacian Erosion, an image deblurring technique for multi-plane Gamma-cameras, has been developed and tested for planar imaging using a GEANT4 Monte Carlo model of the Pixelated Emission Detector for RadioisOtopes (PEDRO) as a test platform. A contrast and Derenzo-like phantom composed of I-125 were both employed to investigate the dependence of detection plane and pinhole geometry on the performance of Laplacian Erosion. Three different pinhole geometries were tested. It was found that, for the test system, the performance of Laplacian Erosion was inversely proportional to the detection plane offset, and directly proportional to the pinhole diameter. All tested pinhole geometries saw a reduction in the level of image blurring associated with the pinhole geometry. However, the reduction in image blurring came at the cost of signal to noise ratio in the image. The application of Laplacian Erosion was shown to reduce the level of image blurring associated with pinhole geometry and improve recovered image quality in multi-plane Gamma-cameras for the targeted radiotracer I-125. |
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Series Issue |
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Edition |
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ISSN |
0018-9499 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000325827200020 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
1609 |
Permanent link to this record |
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Author |
Barrientos, D.; Gonzalez, V.; Bellato, M.; Gadea, A.; Bazzacco, D.; Blasco, J.M.; Bortolato, D.; Egea, F.J.; Isocrate, R.; Pullia, A.; Rampazzo, G.; Sanchis, E.; Triossi, A. |
Title |
Multiple Register Synchronization With a High-Speed Serial Link Using the Aurora Protocol |
Type |
Journal Article |
Year |
2013 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
Volume |
60 |
Issue |
5 |
Pages |
3521-3525 |
Keywords |
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Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
In this work, the development and characterization of a multiple synchronous registers interface communicating with a high-speed serial link and using the Aurora protocol is presented. A detailed description of the developing process and the characterization methods and hardware test benches are also included. This interface will implement the slow control buses of the digitizer cards for the second generation of electronics for the Advanced GAmma Tracking Array (AGATA). |
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ISSN |
0018-9499 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000325827700014 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
1612 |
Permanent link to this record |
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Author |
Barrientos, D.; Bellato, M.; Bazzacco, D.; Bortolato, D.; Cocconi, P.; Gadea, A.; Gonzalez, V.; Gulmini, M.; Isocrate, R.; Mengoni, D.; Pullia, A.; Recchia, F.; Rosso, D.; Sanchis, E.; Toniolo, N.; Ur, C.A.; Valiente-Dobon, J.J. |
Title |
Performance of the Fully Digital FPGA-Based Front-End Electronics for the GALILEO Array |
Type |
Journal Article |
Year |
2015 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
Volume |
62 |
Issue |
6 |
Pages |
3134-3139 |
Keywords |
FPGA; front-end electronics; gamma-ray spectroscopy; germanium detectors |
Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
In this work we present the architecture and results of a fully digital Front End Electronics (FEE) read out system developed for the GALILEO array. The FEE system, developed in collaboration with the Advanced Gamma Tracking Array (AGATA) collaboration, is composed of three main blocks: preamplifiers, digitizers and preprocessing electronics. The slow control system contains a custom Linux driver, a dynamic library and a server implementing network services. This work presents the first results of the digital FEE system coupled with a GALILEO germanium detector, which has demonstrated the capability to achieve an energy resolution of 1.53% at an energy of 1.33 MeV, similar to the one obtained with a conventional analog system. While keeping a good performance in terms of energy resolution, digital electronics will allow to instrument the full GALILEO array with a versatile system with high integration and low power consumption and costs. |
Address |
[Barrientos, D.; Bortolato, D.; Cocconi, P.; Gulmini, M.; Rosso, D.; Toniolo, N.; Valiente-Dobon, J. J.] Ist Nazl Fis Nucl, Lab Nazl Legnaro, I-35020 Padua, Italy, Email: diego.barrientos@lnl.infn.it |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
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English |
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Edition |
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ISSN |
0018-9499 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000372013500005 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
2612 |
Permanent link to this record |
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Author |
Boronat, M.; Marinas, C.; Frey, A.; Garcia, I.; Schwenker, B.; Vos, M.; Wilk, F. |
Title |
Physical Limitations to the Spatial Resolution of Solid-State Detectors |
Type |
Journal Article |
Year |
2015 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
Volume |
62 |
Issue |
1 |
Pages |
381-386 |
Keywords |
Charged particle tracking; silicon detectors; solid state devices |
Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
In this paper we explore the effect of delta-ray emission and fluctuations in the signal deposition on the detection of charged particles in silicon-based detectors. We show that these two effects ultimately limit the resolution that can be achieved by interpolation of the signal in finely segmented position-sensitive solid-state devices. |
Address |
[Boronat, M.; Garcia, I.; Vos, M.] IFIC UVEG CSIC, E-46980 Valencia, Spain, Email: marcel.vos@ific.uv.es |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
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Language |
English |
Summary Language |
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Series Issue |
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Edition |
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ISSN |
0018-9499 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000349672900025 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
2140 |
Permanent link to this record |
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Author |
Bouhova-Thacker, E.; Kostyukhin, V.; Koffas, T.; Liebig, W.; Limper, M.; Piacquadio, G.N.; Prokofiev, K.; Weiser, C.; Wildauer, A. |
Title |
Expected Performance of Vertex Reconstruction in the ATLAS Experiment at the LHC |
Type |
Journal Article |
Year |
2010 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
Volume |
57 |
Issue |
2 |
Pages |
760-767 |
Keywords |
Data analysis; data reconstruction; high energy physics; pattern recognition; reconstruction algorithms; tracking; vertex detectors |
Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
In the harsh environment of the Large Hadron Collider at CERN (design luminosity of 10(34) cm(-2) s(-1)) efficient reconstruction of vertices is crucial for many physics analyses. Described in this paper is the expected performance of the vertex reconstruction used in the ATLAS experiment. The algorithms for the reconstruction of primary and secondary vertices as well as for finding photon conversions and vertex reconstruction in jets are described. The implementation of vertex algorithms which follows a very modular design based on object-oriented C++ is presented. A user-friendly concept allows event reconstruction and physics analyses to compare and optimize their choice among different vertex reconstruction strategies. The performance of implemented algorithms has been studied on a variety of Monte Carlo samples and results are presented. |
Address |
[Bouhova-Thacker, Eva] Univ Lancaster, Lancaster LA1 4YB, England, Email: bouhova@mail.cern.ch |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
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Language |
English |
Summary Language |
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Series Editor |
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Series Issue |
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Edition |
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ISSN |
0018-9499 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000276679200006 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
260 |
Permanent link to this record |
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Author |
Cabello, J.; Torres-Espallardo, I.; Gillam, J.E.; Rafecas, M. |
Title |
PET Reconstruction From Truncated Projections Using Total-Variation Regularization for Hadron Therapy Monitoring |
Type |
Journal Article |
Year |
2013 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
Volume |
60 |
Issue |
5 |
Pages |
3364-3372 |
Keywords |
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Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
Hadron therapy exploits the properties of ion beams to treat tumors by maximizing the dose released to the target and sparing healthy tissue. With hadron beams, the dose distribution shows a relatively low entrance dose which rises sharply at the end of the range, providing the characteristic Bragg peak that drops quickly thereafter. It is of critical importance in order not to damage surrounding healthy tissues and/or avoid targeting underdosage to know where the delivered dose profile ends-the location of the Bragg peak. During hadron therapy, short-lived beta(+)-emitters are produced along the beam path, their distribution being correlated with the delivered dose. Following positron annihilation, two photons are emitted, which can be detected using a positron emission tomography (PET) scanner. The low yield of emitters, their short half-life, and the wash out from the target region make the use of PET, even only a few minutes after hadron irradiation, a challenging application. In-beam PET represents a potential candidate to estimate the distribution of beta(+)-emitters during or immediately after irradiation, at the cost of truncation effects and degraded image quality due to the partial rings required of the PET scanner. Time-of-flight (ToF) information can potentially be used to compensate for truncation effects and to enhance image contrast. However, the highly demanding timing performance required in ToF-PET makes this option costly. Alternatively, the use of maximum-a-posteriori-expectation-maximization (MAP-EM), including total variation (TV) in the cost function, produces images with low noise, while preserving spatial resolution. In this paper, we compare data reconstructed with maximum-likelihood-expectation-maximization (ML-EM) and MAP-EM using TV as prior, and the impact of including ToF information, from data acquired with a complete and a partial-ring PET scanner, of simulated hadron beams interacting with a polymethyl methacrylate (PMMA) target. The results show that MAP-EM, in the absence of ToF information, produces lower noise images and more similar data compared to the simulated beta(+) distributions than ML-EM with ToF information in the order of 200-600 ps. The investigation is extended to the combination of MAP-EM and ToF information to study the limit of performance using both approaches. |
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Edition |
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ISSN |
0018-9499 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000325827200023 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
1610 |
Permanent link to this record |
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Author |
Tetrault, M.A.; Oliver, J.F.; Bergeron, M.; Lecomte, R.; Fontaine, R. |
Title |
Real Time Coincidence Detection Engine for High Count Rate Timestamp Based PET |
Type |
Journal Article |
Year |
2010 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
Volume |
57 |
Issue |
1 |
Pages |
117-124 |
Keywords |
Coincidence detection; Positron Emission Tomography (PET) |
Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
Coincidence engines follow two main implementation flows: timestamp based systems and AND-gate based systems. The latter have been more widespread in recent years because of its lower cost and high efficiency. However, they are highly dependent on the selected electronic components, they have limited flexibility once assembled and they are customized to fit a specific scanner's geometry. Timestamp based systems are gathering more attention lately, especially with high channel count fully digital systems. These new systems must however cope with important singles count rates. One option is to record every detected event and postpone coincidence detection offline. For daily use systems, a real time engine is preferable because it dramatically reduces data volume and hence image preprocessing time and raw data management. This paper presents the timestamp based coincidence engine for the LabPET(TM), a small animal PET scanner with up to 4608 individual readout avalanche photodiode channels. The engine can handle up to 100 million single events per second and has extensive flexibility because it resides in programmable logic devices. It can be adapted for any detector geometry or channel count, can be ported to newer, faster programmable devices and can have extra modules added to take advantage of scanner-specific features. Finally, the user can select between full processing mode for imaging protocols and minimum processing mode to study different approaches for coincidence detection with offline software. |
Address |
[Tetrault, M. -A.; Fontaine, R.] Univ Sherbrooke, Dept Elect & Comp Engn, Sherbrooke, PQ J1K 2R1, Canada, Email: Marc-Andre.Tetrault@USherbrooke.ca |
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Thesis |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0018-9499 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000274391000016 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ elepoucu @ |
Serial |
500 |
Permanent link to this record |