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Author Muñoz, E.; Barrio, J.; Etxebeste, A.; Ortega, P.G.; Lacasta, C.; Oliver, J.F.; Solaz, C.; Llosa, G. doi  openurl
  Title Performance evaluation of MACACO: a multilayer Compton camera Type Journal Article
  Year 2017 Publication Physics in Medicine and Biology Abbreviated Journal (down) Phys. Med. Biol.  
  Volume 62 Issue 18 Pages 7321-7341  
  Keywords Compton imaging; Compton camera; continuous LaBr3 crystal; silicon photomultiplier; hadron therapy  
  Abstract Compton imaging devices have been proposed and studied for a wide range of applications. We have developed a Compton camera prototype which can be operated with two or three detector layers based on monolithic lanthanum bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs), to be used for proton range verification in hadron therapy. In this work, we present the results obtained with our prototype in laboratory tests with radioactive sources and in simulation studies. Images of a Na-22 and an Y-88 radioactive sources have been successfully reconstructed. The full width half maximum of the reconstructed images is below 4 mm for a Na-22 source at a distance of 5 cm.  
  Address [Munoz, Enrique; Barrio, John; Etxebeste, Ane; Ortega, Pablo G.; Lacasta, Carlos; Oliver, Josep F.; Solaz, Carles; Llosa, Gabriela] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000408229900003 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 3253  
Permanent link to this record
 

 
Author Etxebeste, A.; Barrio, J.; Bernabeu, J.; Lacasta, C.; Llosa, G.; Muñoz, E.; Ros, A.; Oliver, J.F. doi  openurl
  Title Study of sensitivity and resolution for full ring PET prototypes based on continuous crystals and analytical modeling of the light distribution Type Journal Article
  Year 2019 Publication Physics in Medicine and Biology Abbreviated Journal (down) Phys. Med. Biol.  
  Volume 64 Issue 3 Pages 035015 - 17pp  
  Keywords continuous crystals; NEMA NU 4-2008; positron emission tomography (PET); Monte Carlo simulations; image reconstruction; depth of interaction  
  Abstract Sensitivity and spatial resolution are the main parameters to maximize in the performance of a PET scanner. For this purpose, detectors consisting of a combination of continuous crystals optically coupled to segmented photodetectors have been employed. With the use of continuous crystals the sensitivity is increased with respect to the pixelated crystals. In addition, spatial resolution is no longer limited to the crystal size. The main drawback is the difficulty in determining the interaction position. In this work, we present the characterization of the performance of a full ring based on cuboid continuous crystals coupled to SiPMs. To this end, we have employed the simulations developed in a previous work for our experimental detector head. Sensitivity could be further enhanced by using tapered crystals. This enhancement is obtained by increasing the solid angle coverage, reducing the wedge-shaped gaps between contiguous detectors. The performance of the scanners based on both crystal geometries was characterized following NEMA NU 4-2008 standardized protocol in order to compare them. An average sensitivity gain over the entire axial field of view of 13.63% has been obtained with tapered geometry while similar performance of the spatial resolution has been proven with both scanners. The activity at which NECR and true peak occur is smaller and the peak value is greater for tapered crystals than for cuboid crystals. Moreover, a higher degree of homogeneity was obtained in the sensitivity map due to the tighter packing of the crystals, which reduces the gaps and results in a better recovery of homogeneous regions than for the cuboid configuration. Some of the results obtained, such as spatial resolution, depend on the interaction position estimation and may vary if other method is employed.  
  Address [Etxebeste, Ane; Barrio, John; Bernabeu, Jose; Lacasta, Carlos; Llosa, Gabriela; Munoz, Enrique; Ros, Ana; Oliver, Josef F.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: ane.etxebeste@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000457182500004 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 3897  
Permanent link to this record
 

 
Author Scandale, W. et al; Lari, L. doi  openurl
  Title Optimization of the crystal assisted collimation of the SPS beam Type Journal Article
  Year 2013 Publication Physics Letters B Abbreviated Journal (down) Phys. Lett. B  
  Volume 726 Issue 1-3 Pages 182-186  
  Keywords Accelerator; Beam collimation; Crystal; Channeling  
  Abstract The possibility for optimization of crystal assisted collimation has been studied at the CERN SPS for stored beams of protons and Pb ions with 270 GeV/c per unit charge. A bent silicon crystal used as a primary collimator deflects halo particles in the channeling regime, directing them into a tungsten absorber. In channeling conditions a strong reduction of off-momentum particle numbers produced in the crystal and absorber, which form collimation leakage, has been observed in the first high dispersion (HD) area downstream. The present study shows that the collimation leakage is minimal for some values of the absorber offset relative to the crystal. The optimal offset value is larger for Pb ions because of their considerably larger ionization losses in the crystal, which cause large increases of particle betatron oscillation amplitudes. The optimal absorber offset allows obtaining maximal efficiency of crystal-assisted collimation.  
  Address [Scandale, W.; Arduini, G.; Butcher, M.; Cerutti, F.; Gilardoni, S.; Lari, L.; Lechner, A.; Losito, R.; Masi, A.; Mereghetti, A.; Metral, E.; Mirarchi, D.; Montesano, S.; Redaelli, S.; Schoofs, P.; Smirnov, G.] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland, Email: alexander.taratin@cern.ch  
  Corporate Author Thesis  
  Publisher Elsevier Science Bv Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0370-2693 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000326482200020 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1694  
Permanent link to this record
 

 
Author Scandale, W. et al; Lari, L. doi  openurl
  Title Observation of nuclear dechanneling length reduction for high energy protons in a short bent crystal Type Journal Article
  Year 2015 Publication Physics Letters B Abbreviated Journal (down) Phys. Lett. B  
  Volume 743 Issue Pages 440-443  
  Keywords Crystal; Channeling; Beam; Deflection  
  Abstract Deflection of 400 GeV/c protons by a short bent silicon crystal was studied at the CERN SPS. It was shown that the dechanneling probability increases while the dechanneling length decreases with an increase of incident angles of particles relative to the crystal planes. The observation of the dechanneling length reduction provides evidence of the particle population increase at the top levels of transverse energies in the potential well of the planar channels. (C) 2015 The Authors. Published by Elsevier B.V.  
  Address [Scandale, W.; Arduini, G.; Butcher, M.; Cerutti, F.; Garattini, M.; Gilardoni, S.; Lari, L.; Lechner, A.; Losito, R.; Masi, A.; Mereghetti, A.; Metral, E.; Mirarchi, D.; Montesano, S.; Redaelli, S.; Rossi, R.; Schoofs, P.; Smirnov, G.] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland, Email: alexander.taratin@cern.ch  
  Corporate Author Thesis  
  Publisher Elsevier Science Bv Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0370-2693 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000352147500065 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2201  
Permanent link to this record
 

 
Author Scandale, W et al; Lari, L. doi  openurl
  Title Deflection of high energy protons by multiple volume reflections in a modified multi-strip silicon deflector Type Journal Article
  Year 2014 Publication Nuclear Instruments & Methods in Physics Research B Abbreviated Journal (down) Nucl. Instrum. Methods Phys. Res. B  
  Volume 338 Issue Pages 108-111  
  Keywords Accelerator; Beam collimation; Crystal; Channeling; Volume reflection  
  Abstract The effect of multiple volume reflections in one crystal was observed in each of several bent silicon strips for 400 GeV/c protons. This considerably increased the particle deflections. Some particles were also deflected due to channeling in one of the subsequent strips. As a result, the incident beam was strongly spread because of opposite directions of the deflections. A modified multi-strip deflector produced by periodic grooves on the surface of a thick silicon plate was used for these measurements. This technique provides perfect mutual alignment between crystal strips. Such multi-strip deflector may be effective for collider beam halo collimation and a study is planned at the CERN SPS circulating beam.  
  Address [Scandale, W.; Arduini, G.; Butcher, M.; Cerutti, F.; Gilardoni, S.; Lari, L.; Lechner, A.; Losito, R.; Masi, A.; Mereghetti, A.; Metral, E.; Mirarchi, D.; Montesano, S.; Redaelli, S.; Schoofs, P.; Smirnov, G.] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland  
  Corporate Author Thesis  
  Publisher Elsevier Science Bv Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0168-583x ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000343390400016 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1974  
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