Abstract: This work presents a study of the Al-27(alpha, n) reaction over an extended energy range (3.5-15 MeV) relative to previous datasets, performed at the Centro de Micro-An & aacute;lisis de Materiales in Madrid. Thick-target yields were obtained from activation by the online measurement of the decay of the P-30 reaction product, using the recently developed Gamma-detection Array for Reaction Yield measurements. The results show good agreement with existing data and confirm the newest thick-target yields at low energies. Direct Al-27(alpha, n gamma)P-30 gamma-yields were measured in order to address (alpha, n) branches to excited states in P-30. The angular dependence of the emitted prompt gamma rays was investigated, revealing significant differences as a function of angle with respect to the beam direction. The results provide benchmark data for future (alpha, n) yield studies using online activation measurements and prompt gamma-ray detection.