Abstract: Charge-parity (CP) violation in the tau-charm energy region is a promising area for sensitive tests of Standard Model (SM) predictions and searches for new, beyond the SM physics. A future Tau-Charm Facility that operates at center-of-mass energies between 2.0 and 7.0 GeV, with a peak luminosity of 0.5 & times; 1035 cm-2 s-1, would provide huge numbers of hadrons and tau (tau) leptons that are produced in low-background environments and with well understood kinematic properties. In this report, prospects for unique studies of CP violation in the decay of charmed hadrons, and in the production and decay of hyperons and tau leptons at a next-generation tau-charm facility are discussed. In addition, opportunities for improved tests of CPT invariance test in K0-K & strns;0 mixing are presented. (c) 2026 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).