Abstract: We give precise details to support that observations of gravitational lensing at scales of individual, groups and clusters of galaxies can be understood in terms of nonNewtonian gravitational interactions with a relativistic structure compatible with the Einstein Equivalence Principle. This result is derived on very general grounds without knowing the underlying structure of the gravitational field equations. As such, any developed gravitational theory built to deal with these astrophysical scales needs to reproduce the obtained results of this article.