Abstract: We present a detailed discussion of Sommerfeld enhancements in neutralino dark matter relic abundance calculations for several popular benchmark scenarios in the general MSSM. Our analysis is focused on models with heavy wino- and higgsino-like neutralino LSI' and models interpolating between these two scenarios. This work is the first phenomenological application of effective field theory methods that we have developed in earlier work and that allow for the consistent study of Sommerfeld enhancements in nonrelativistic neutralino and chargino co-annihilation reactions within the general MSSM, away from the pure-wino and pure-higgsino limits.