Abstract: We investigate a beyond standard model (SM) portal scenario for dark matter (DM) particle with leptoquark being the mediator field. Leptoquark, a colored particle having both baryon and lepton number, allows the DM to interact with the SM fields via renormalizable interaction. By focusing on a vector leptoquark portal with Majorana fermion DM candidate, we find the only unknown coupling in the model is sensitive to all three main features of a DM model namely, relic density, direct detection as well as indirect detection, while being consistent with collider data. We explore the parameter space of the portal with minimum of its field content and find that AMS-02 data for antiproton flux imposes stringent bound till date and excludes the DM mass up to 400 GeV. The LUX 2016 data for DM-neutron scattering cross section allows the region compatible with relic density, however the future sensitivity of LUX-ZEPLIN experiment can probe the model up to its perturbative limit.