Abstract: This paper investigates the Casimir energy modifications due to the Lorentz-violating CPT-even contribution in an extension of the scalar QED. We have considered the complex scalar field satisfying Dirichlet boundary conditions between two parallel plates separated by a small distance. An appropriate tensor parametrization allowed us to study the Casimir effect in three different configurations: isotropic, anisotropic parity-odd, and anisotropic parity-even. We have shown that the Lorentz-violating contributions can promote either an increase or a decrease in the Casimir energy evaluated in the isotropic configuration, depending on whether the violation parameters are taking as positive or negative values. On the other hand, for the anisotropic parity-even case the Casimir energy only decreases, while for the anisotropic parity-odd cases it only increases. Therefore, from these last two results it seems that the Casimir energy is sensitive to the parity of Lorentz-violating coefficients.

Abstract: We report on a hybrid in-beam PET and prompt-gamma Compton imaging system aimed at quasi real-time ion-range verification in proton-therapy treatments. Proof-of-concept experiments were carried out at the radiobiology beam line of the CNA cyclotron facility using a set of two synchronous Compton imagers and different target materials. The time structure of the 18 MeV proton beam was shaped with a series of beam-on and beam-off intervals, thereby mimicking a pulsed proton beam on a long time scale. During beam-on intervals, Compton imagingwas performed utilizing the high energy. -rays promptly emitted from the nuclear reactions occurring in the targets. In the course of the beam-off intervals in situ positron-emission tomography was accomplished with the same imagers using the beta+ decay of activated nuclei. The targets used were stacks of different materials covering also various proton ranges and energies. A systematic study on the performance of these two complementary imaging techniques is reported and the experimental results interpreted on the basis ofMonte Carlo calculations. The results demonstrate the possibility to combine both imaging techniques in a concomitant way, where high-efficiency prompt-gamma imaging is complemented with the high spatial accuracy of PET. Empowered by these results we suggest that a pulsed beam with a suitable duty cycle, in conjunction with in situ Compton- and PET-imaging may help to attain complementary information and quasi real-time range monitoring with high accuracy.

Abstract: Magnetic monopoles have been a subject of interest since Dirac established the relation between the existence of monopoles and charge quantization. The intense experimental search carried thus far has not met with success. The Large Hadron Collider is reaching energies never achieved before allowing the search for exotic particles in the TeV mass range. In a continuing effort to discover these rare particles we propose here other ways to detect them. We study the observability of monopoles and monopolium, a monopole-antimonopole bound state, at the Large Hadron Collider in the gamma gamma channel for monopole masses in the range 500-1000 GeV. We conclude that LHC is an ideal machine to discover monopoles with masses below 1 TeV at present running energies and with 5 fb(-1) of integrated luminosity.

Abstract: We study the energy loss of excited monopolium in an atomic medium. We perform a classical calculation in line with a similar calculation performed for charged particles which leads in the non-relativistic limit to the Bethe-Bloch formula except for the density dependence of the medium, which we do not consider in this paper. Our result shows that for maximally deformed Rydberg states, the ionization of monopolium in a light atomic medium is similar to that of light ions.

Abstract: Compton cameras can offer advantages over gamma cameras for some applications, since they are well suited for multitracer imaging and for imaging high-energy radiotracers, such as those employed in radionuclide therapy. While in conventional clinical settings state-of-the-art Compton cameras cannot compete with well-established methods such as PET and SPECT, there are specific scenarios in which they can constitute an advantageous alternative. The combination of PET and Compton imaging can benefit from the improved resolution and sensitivity of current PET technology and, at the same time, overcome PET limitations in the use of multiple radiotracers. Such a system can provide simultaneous assessment of different radiotracers under identical conditions and reduce errors associated with physical factors that can change between acquisitions. Advances are being made both in instrumentation developments combining PET and Compton cameras for multimodal or three-gamma imaging systems, and in image reconstruction, addressing the challenges imposed by the combination of the two modalities or the new techniques. This review article summarizes the advances made in Compton cameras for medical imaging and their combination with PET.