Abstract: The introduction of model-based dose calculation algorithms (MBDCAs) in brachytherapy provides an opportunity for a more accurate dose calculation and opens the possibility for novel, innovative treatment modalities. The joint AAPM, ESTRO, and ABG Task Group 186 (TG-186) report provided guidance to early adopters. However, the commissioning aspect of these algorithms was described only in general terms with no quantitative goals. This report, from the Working Group on Model-Based Dose Calculation Algorithms in Brachytherapy, introduced a field-tested approach to MBDCA commissioning. It is based on a set of well-characterized test cases for which reference Monte Carlo (MC) and vendor-specific MBDCA dose distributions are available in a Digital Imaging and Communications in Medicine-Radiotherapy (DICOM-RT) format to the clinical users. The key elements of the TG-186 commissioning workflow are now described in detail, and quantitative goals are provided. This approach leverages the well-known Brachytherapy Source Registry jointly managed by the AAPM and the Imaging and Radiation Oncology Core (IROC) Houston Quality Assurance Center (with associated links at ESTRO) to provide open access to test cases as well as step-by-step user guides. While the current report is limited to the two most widely commercially available MBDCAs and only for Ir-192-based afterloading brachytherapy at this time, this report establishes a general framework that can easily be extended to other brachytherapy MBDCAs and brachytherapy sources. The AAPM, ESTRO, ABG, and ABS recommend that clinical medical physicists implement the workflow presented in this report to validate both the basic and the advanced dose calculation features of their commercial MBDCAs. Recommendations are also given to vendors to integrate advanced analysis tools into their brachytherapy treatment planning system to facilitate extensive dose comparisons. The use of the test cases for research and educational purposes is further encouraged.

Abstract: We explore a simple but extremely predictive extension of the scotogenic model. We promote the scotogenic symmetry Z(2) to the flavour non-Abelian symmetry sigma(81), which can also automatically protect dark matter stability. In addition, sigma(81) leads to striking predictions in the lepton sector: only Inverted Ordering is realised, the absolute neutrino mass scale is predicted to be m(lightest)approximate to 7.5x10(-4) eV and the Majorana phases are correlated in such a way that vertical bar m(ee)vertical bar approximate to 0.018 eV. The model also leads to a strong correlation between the solar mixing angle theta(12) and delta(CP), which may be falsified by the next generation of neutrino oscillation experiments. The setup is minimal in the sense that no additional symmetries or flavons are required.

Abstract: Using numerical methods, we investigate the absorption properties of a family of nonsingular solutions which arise in different metric-affine theories, such as quadratic and Born-Infeld gravity. These solutions continuously interpolate between Schwarzschild black holes and naked solitons with wormhole topology. The resulting spectrum is characterized by a series of quasibound states excitations, associated with the existence of a stable photonsphere.

Abstract: The framed Standard Model (FSM) predicts a 0(+) boson with mass around 20 MeV in the “hidden sector,” which mixes at tree level with the standard Higgs hW and hence acquires small couplings to quarks and leptons which can be calculated in the FSM apart from the mixing parameter rho Uh. The exchange of this mixed state U will contribute to g – 2 and to the Lamb shift. By adjusting rho Uh alone, it is found that the FSM can satisfy all present experimental bounds on the g – 2 and Lamb shift anomalies for μand e, and for the latter for both hydrogen and deuterium. The FSM predicts also a 1(-) boson in the “hidden sector” with a mass of 17 MeV, that is, right on top of the Atomki anomaly X. This mixes with the photon at 1-loop level and couples thereby like a dark photon to quarks and leptons. It is however a compound state and is thought likely to possess additional compound couplings to hadrons. By adjusting the mixing parameter and the X's compound coupling to nucleons, the FSM can reproduce the production rate of the X in beryllium decay as well as satisfy all the bounds on X listed so far in the literature. The above two results are consistent in that the U, being 0(+), does not contribute to the Atomki anomaly if parity and angular momentum are conserved, while X, though contributing to g – 2 and Lamb shift, has smaller couplings than U and can, at first instance, be neglected there. Thus, despite the tentative nature of the three anomalies in experiment on the one hand and of the FSM as theory on the other, the accommodation of the former in the latter has strengthened the credibility of both. Indeed, if this FSM interpretation were correct, it would change the whole aspect of the anomalies from just curiosities to windows into a vast hitherto hidden sector comprising at least in part the dark matter which makes up the bulk of our universe.

Abstract: We extend the method of adiabatic regularization by introducing an arbitrary parameter μfor a scalar field with quartic self-coupling in a Friedmann-Lemaitre-Robertson-Walker spacetime at one-loop order. The subtraction terms constructed from this extended version allow us to define a preferred vacuum state at a fixed time ri 1/4 ri0 for this theory. We compute this vacuum state for two commonly used background fields in cosmology, specially in the context of preheating. We also give a possible prescription for an adequate value for mu.