Renner, J. et al, Romo-Luque, C., Carrion, J. V., Diaz, J., Martinez, A., Querol, M., et al. (2022). Monte Carlo characterization of PETALO, a full-body liquid xenon-based PET detector. J. Instrum., 17(5), P05044–17pp.
Abstract: New detector approaches in Positron Emission Tomography imaging will play an important role in reducing costs, lowering administered radiation doses, and improving overall performance. PETALO employs liquid xenon as the active scintillating medium and UV-sensitive silicon photomultipliers for scintillation readout. The scintillation time in liquid xenon is fast enough to register time-of-flight information for each detected coincidence, and sufficient scintillation is produced with low enough fluctuations to obtain good energy resolution. The present simulation study examines a full-body-sized PETALO detector and evaluates its potential performance in PET image reconstruction.
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Salor-Iguiñiz, N., Benlloch-Rodriguez, J. M., Esteve, R., Alvarez, V., Ballester, F., Gadea, R., et al. (2025). Evaluation of coincidence time resolution in a liquid xenon detector with silicon photomultipliers. Phys. Rev. Res., 7(3), 033089–9pp.
Abstract: This work explores the combination of liquid xenon as a scintillating medium and silicon photomultipliers as a readout in Positron Emission Tomography (PET) for enhanced Time-Of-Flight resolution. We present the results of our first prototype optimized to maximize light collection using high photodetection efficiency (PDE), VUV-sensitive sensors and to minimize time fluctuations. We report a coincidence time resolution of 281 +/- 2 ps FWHM, obtained using a 22Na calibration source. This result is competitive with the current state-of-the-art PET scanners and represents a significant step forward in the development of liquid xenon as a viable alternative to conventional scintillators in PET technology.
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