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Author |
Valderrama, M.; Crepon, B.; Botella-Soler, V.; Martinerie, J.; Hasboun, D.; Alvarado-Rojas, C.; Baulac, M.; Adam, C.; Navarro, V.; Le Van Quyen, M. |
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Title |
Human Gamma Oscillations during Slow Wave Sleep |
Type |
Journal Article |
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Year |
2012 |
Publication |
Plos One |
Abbreviated Journal |
PLoS One |
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Volume |
7 |
Issue |
4 |
Pages |
e33477 - 14pp |
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Keywords |
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Abstract |
Neocortical local field potentials have shown that gamma oscillations occur spontaneously during slow-wave sleep (SWS). At the macroscopic EEG level in the human brain, no evidences were reported so far. In this study, by using simultaneous scalp and intracranial EEG recordings in 20 epileptic subjects, we examined gamma oscillations in cerebral cortex during SWS. We report that gamma oscillations in low (30-50 Hz) and high (60-120 Hz) frequency bands recurrently emerged in all investigated regions and their amplitudes coincided with specific phases of the cortical slow wave. In most of the cases, multiple oscillatory bursts in different frequency bands from 30 to 120 Hz were correlated with positive peaks of scalp slow waves (“IN-phase'' pattern), confirming previous animal findings. In addition, we report another gamma pattern that appears preferentially during the negative phase of the slow wave (”ANTI-phase'' pattern). This new pattern presented dominant peaks in the high gamma range and was preferentially expressed in the temporal cortex. Finally, we found that the spatial coherence between cortical sites exhibiting gamma activities was local and fell off quickly when computed between distant sites. Overall, these results provide the first human evidences that gamma oscillations can be observed in macroscopic EEG recordings during sleep. They support the concept that these high-frequency activities might be associated with phasic increases of neural activity during slow oscillations. Such patterned activity in the sleeping brain could play a role in off-line processing of cortical networks. |
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Address |
[Valderrama, Mario; Crepon, Benoit; Martinerie, Jacques; Hasboun, Dominique; Alvarado-Rojas, Catalina; Baulac, Michel; Adam, Claude; Navarro, Vincent; Le Van Quyen, Michel] Univ Paris 06, Ctr Rech Inst Cerveau & Moelle Epiniere CRICM, INSERM,UMRS 975, Hop La Pitie Salpetriere,CNRS,UMR 7225, Paris, France, Email: quyen@t-online.de |
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Public Library Science |
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English |
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ISSN |
1932-6203 |
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Notes |
WOS:000304855200013 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1058 |
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Author |
Botella-Soler, V.; Valderrama, M.; Crepon, B.; Navarro, V.; Le Van Quyen, M. |
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Title |
Large-Scale Cortical Dynamics of Sleep Slow Waves |
Type |
Journal Article |
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Year |
2012 |
Publication |
Plos One |
Abbreviated Journal |
PLoS One |
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Volume |
7 |
Issue |
2 |
Pages |
e30757 - 10pp |
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Keywords |
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Abstract |
Slow waves constitute the main signature of sleep in the electroencephalogram (EEG). They reflect alternating periods of neuronal hyperpolarization and depolarization in cortical networks. While recent findings have demonstrated their functional role in shaping and strengthening neuronal networks, a large-scale characterization of these two processes remains elusive in the human brain. In this study, by using simultaneous scalp EEG and intracranial recordings in 10 epileptic subjects, we examined the dynamics of hyperpolarization and depolarization waves over a large extent of the human cortex. We report that both hyperpolarization and depolarization processes can occur with two different characteristic time durations which are consistent across all subjects. For both hyperpolarization and depolarization waves, their average speed over the cortex was estimated to be approximately 1 m/s. Finally, we characterized their propagation pathways by studying the preferential trajectories between most involved intracranial contacts. For both waves, although single events could begin in almost all investigated sites across the entire cortex, we found that the majority of the preferential starting locations were located in frontal regions of the brain while they had a tendency to end in posterior and temporal regions. |
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Address |
[Botella-Soler, Vicente] Univ Valencia, Dept Fis Teor, CSIC, Valencia, Spain, Email: quyen@t-online.de |
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Public Library Science |
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English |
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Series Editor |
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ISSN |
1932-6203 |
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Conference |
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Notes |
WOS:000302853600065 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
986 |
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Author |
Grieser, M. et al; Rubio, B. |
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Title |
Storage ring at HIE-ISOLDE Technical design report |
Type |
Journal Article |
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Year |
2012 |
Publication |
European Physical Journal-Special Topics |
Abbreviated Journal |
Eur. Phys. J.-Spec. Top. |
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Volume |
207 |
Issue |
1 |
Pages |
1-117 |
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Abstract |
We propose to install a storage ring at an ISOL-type radioactive beam facility for the first time. Specifically, we intend to setup the heavy-ion, low-energy ring TSR at the HIE-ISOLDE facility in CERN, Geneva. Such a facility will provide a capability for experiments with stored secondary beams that is unique in the world. The envisaged physics programme is rich and varied, spanning from investigations of nuclear ground-state properties and reaction studies of astrophysical relevance, to investigations with highly-charged ions and pure isomeric beams. The TSR might also be employed for removal of isobaric contaminants from stored ion beams and for systematic studies within the neutrino beam programme. In addition to experiments performed using beams recirculating within the ring, cooled beams can also be extracted and exploited by external spectrometers for high-precision measurements. The existing TSR, which is presently in operation at the Max-Planck Institute for Nuclear Physics in Heidelberg, is well-suited and can be employed for this purpose. The physics cases as well as technical details of the existing ring facility and of the beam and infrastructure requirements at HIE-ISOLDE are discussed in the present technical design report. |
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Address |
[Grieser, M.; Blaum, K.; Fischer, D.; von Hahn, R.; Kreim, S.; Repnow, R.; Schwalm, D.; Shubina, D.; Winckler, N.; Wolf, A.] Max Planck Inst Kernphys, D-69117 Heidelberg, Germany |
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Springer Heidelberg |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1951-6355 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000303985700001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1014 |
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Author |
n_TOF Collaboration (Guerrero, C. et al); Giubrone, G.; Tain, J.L. |
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Title |
Simultaneous measurement of neutron-induced capture and fission reactions at CERN |
Type |
Journal Article |
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Year |
2012 |
Publication |
European Physical Journal A |
Abbreviated Journal |
Eur. Phys. J. A |
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Volume |
48 |
Issue |
3 |
Pages |
29 - 9pp |
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Abstract |
The measurement of the capture cross-section of fissile elements, of utmost importance for the design of innovative nuclear reactors and the management of nuclear waste, faces particular difficulties related to the.-ray background generated in the competing fission reactions. At the CERN neutron time-of-flight facility nTOF we have combined the Total Absorption Calorimeter (TAC) capture detector with a set of three U-235 loaded MicroMegas (MGAS) fission detectors for measuring simultaneously two reactions: capture and fission. The results presented here include the determination of the three detection efficiencies involved in the process: epsilon(TAC)(n, f), epsilon(TAC)(n, gamma) and epsilon(MGAS)(n, f). In the test measurement we have succeeded in measuring simultaneously with a high total efficiency the U-235 capture and fission cross-sections, disentangling accurately the two types of reactions. The work presented here proves that accurate capture cross-section measurements of fissile isotopes are feasible at nTOF. |
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Address |
[Guerrero, C.; Berthoumieux, E.; Andriamonje, S.; Brugger, M.; Calviani, M.; Cerutti, F.; Chiaveri, E.; Chin, M.; Ferrari, A.; Kadi, Y.; Lebbos, E.; Losito, R.; Roman, F.; Rubbia, C.; Tsinganis, A.; Vlachoudis, V.] European Org Nucl Res CERN, Geneva, Switzerland, Email: carlos.guerrero@cern.ch |
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Corporate Author |
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Thesis |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6001 |
ISBN |
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Conference |
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Notes |
WOS:000303537100013 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1017 |
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Author |
HADES Collaboration (Lapidus, K. et al); Diaz, J.; Gil, A. |
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Title |
The HADES-at-FAIR project |
Type |
Journal Article |
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Year |
2012 |
Publication |
Physics of Atomic Nuclei |
Abbreviated Journal |
Phys. Atom. Nuclei |
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Volume |
75 |
Issue |
5 |
Pages |
589-593 |
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Keywords |
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Abstract |
After the completion of the experimental program at SIS18 the HADES setup will migrate to FAIR, where it will deliver high-quality data for heavy-ion collisions in an unexplored energy range of up to 8 A GeV. In this contribution, we briefly present the physics case, relevant detector characteristics and discuss the recently completed upgrade of HADES. |
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Address |
[Lapidus, K.; Chen, J. C.; Epple, E.; Fabbietti, L.; Lalik, R.; Muenzer, R.; Schmah, A.; Siebenson, J.] Excellence Cluster Origin & Struct Universe, Garching, Germany, Email: kirill.lapidus@ph.tum.de |
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Thesis |
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Publisher |
Maik Nauka/Interperiodica/Springer |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1063-7788 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000304621800011 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1046 |
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