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Author Decoster, S.; Cottenier, S.; Wahl, U.; Correia, J.G.; Pereira, L.M.C.; Lacasta, C.; Da Silva, M.R.; Vantomme, A. doi  openurl
  Title Diluted manganese on the bond-centered site in germanium Type Journal Article
  Year 2010 Publication Applied Physics Letters Abbreviated Journal Appl. Phys. Lett.  
  Volume 97 Issue 15 Pages 151914 - 3pp  
  Keywords  
  Abstract The functional properties of Mn-doped Ge depend to large extent on the lattice location of the Mn impurities. Here, we present a lattice location study of implanted diluted Mn by means of electron emission channeling. Surprisingly, in addition to the expected substitutional lattice position, a large fraction of the Mn impurities occupies the bond-centered site. Corroborated by ab initio calculations, the bond-centered Mn is related to Mn-vacancy complexes. These unexpected results call for a reassessment of the theoretical studies on the electrical and magnetic behavior of Mn-doped Ge, hereby including the possible role of Mn-vacancy complexes.  
  Address [Decoster, S.; Pereira, L. M. C.; Vantomme, A.] Katholieke Univ Leuven, Inst Kern & Stralingsfys, B-3001 Louvain, Belgium, Email: stefan.decoster@fys.kuleuven.be  
  Corporate Author Thesis  
  Publisher Amer Inst Physics Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (up) 0003-6951 ISBN Medium  
  Area Expedition Conference  
  Notes ISI:000283216900030 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ elepoucu @ Serial 357  
Permanent link to this record
 

 
Author Peris, J.B.; Davis, P.; Cuevas, J.M.; Nebot, M.; Sanjuan, R. doi  openurl
  Title Distribution of Fitness Effects Caused by Single-Nucleotide Substitutions in Bacteriophage f1 Type Journal Article
  Year 2010 Publication Genetics Abbreviated Journal Genetics  
  Volume 185 Issue 2 Pages 603-U308  
  Keywords  
  Abstract Empirical knowledge of the fitness effects of mutations is important for understanding many evolutionary processes, yet this knowledge is often hampered by several sources of measurement error and bias. Most of these problems can be solved using site-directed mutagenesis to engineer single mutations, an approach particularly suited for viruses due to their small genomes. Here, we used this technique to measure the fitness effect of 100 single-nucleotide substitutions in the bacteriophage f1, a filamentous single-strand DNA virus. We found that approximately one-fifth of all mutations are lethal. Viable ones reduced fitness by 11% on average and were accurately described by a log-normal distribution. More than 90% of synonymous substitutions were selectively neutral, while those affecting intergenic regions reduced fitness by 14% on average. Mutations leading to amino acid substitutions had an overall mean deleterious effect of 37%, which increased to 45% for those changing the amino acid polarity. Interestingly, mutations affecting early steps of the infection cycle tended to be more deleterious than those affecting late steps. Finally, we observed at least two beneficial mutations. Our results confirm that high mutational sensitivity is a general property of viruses with small genomes, including RNA and single-strand DNA viruses infecting animals, plants, and bacteria.  
  Address [Peris, Joan B.; Davis, Paulina; Cuevas, Jose M.; Sanjuan, Rafael] Univ Valencia, Inst Cavanilles Biodiversitat & Biol Evolut, Valencia 46980, Spain, Email: rafael.sanjuan@uv.es  
  Corporate Author Thesis  
  Publisher Genetics Soc Am Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (up) 0016-6731 ISBN Medium  
  Area Expedition Conference  
  Notes ISI:000281905200017 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ elepoucu @ Serial 383  
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Author Bouhova-Thacker, E.; Kostyukhin, V.; Koffas, T.; Liebig, W.; Limper, M.; Piacquadio, G.N.; Prokofiev, K.; Weiser, C.; Wildauer, A. doi  openurl
  Title Expected Performance of Vertex Reconstruction in the ATLAS Experiment at the LHC Type Journal Article
  Year 2010 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.  
  Volume 57 Issue 2 Pages 760-767  
  Keywords Data analysis; data reconstruction; high energy physics; pattern recognition; reconstruction algorithms; tracking; vertex detectors  
  Abstract In the harsh environment of the Large Hadron Collider at CERN (design luminosity of 10(34) cm(-2) s(-1)) efficient reconstruction of vertices is crucial for many physics analyses. Described in this paper is the expected performance of the vertex reconstruction used in the ATLAS experiment. The algorithms for the reconstruction of primary and secondary vertices as well as for finding photon conversions and vertex reconstruction in jets are described. The implementation of vertex algorithms which follows a very modular design based on object-oriented C++ is presented. A user-friendly concept allows event reconstruction and physics analyses to compare and optimize their choice among different vertex reconstruction strategies. The performance of implemented algorithms has been studied on a variety of Monte Carlo samples and results are presented.  
  Address [Bouhova-Thacker, Eva] Univ Lancaster, Lancaster LA1 4YB, England, Email: bouhova@mail.cern.ch  
  Corporate Author Thesis  
  Publisher Ieee-Inst Electrical Electronics Engineers Inc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (up) 0018-9499 ISBN Medium  
  Area Expedition Conference  
  Notes ISI:000276679200006 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 260  
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Author Belver, D.; Cabanelas, P.; Castro, E.; Garzon, J.A.; Gil, A.; Gonzalez-Diaz, D.; Koenig, W.; Traxler, M. doi  openurl
  Title Performance of the Low-Jitter High-Gain/Bandwidth Front-End Electronics of the HADES tRPC Wall Type Journal Article
  Year 2010 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.  
  Volume 57 Issue 5 Pages 2848-2856  
  Keywords Charge to width algorithm; fast amplifying and digitizing electronics; front-end electronics; HADES; time of flight; timing RPC  
  Abstract A front-end electronics (FEE) chain for accurate time measurements has been developed for the new Resistive Plate Chamber (RPC)-based Time-of-Flight (TOF) wall of the High Acceptance Di-Electron Spectrometer (HADES). The wall covers an area of around 8 m(2) divided in 6 sectors. In total, 1122 4-gap timing RPC cells are read-out by 2244 time and charge sensitive channels. The FEE chain consists of 2 custom-made boards: a 4-channel Daughter BOard(DBO) and a 32-channel MotherBOard (MBO). The DBO uses a fast 2 GHz amplifier feeding a dual high-speed discriminator. The time and charge information are encoded, respectively, in the leading edge and the width of an LVDS signal. Each MBO houses up to 8 DBOs providing them regulated voltage supply, threshold values via DACs, test signals and, additionally, routing out a signal proportional to the channel multiplicity needed for a 1st level trigger decision. The MBO delivers LVDS signals to a multi-purpose Trigger Readout Board (TRB) for data acquisition. The FEE allows achieving a system resolution around 75 ps fulfilling comfortably the requirements of the HADES upgrade [1]. The commissioning of the whole RPC wall is finished and the 6 sectors are already mounted in their final position in the HADES spectrometer and ready to take data during the beam-times foreseen for 2010.  
  Address [Belver, Daniel; Cabanelas, P.; Castro, E.; Garzon, J. A.] Univ Santiago Compostela, LabCAF, Santiago De Compostela 15782, Spain, Email: daniel.belver@usc.es  
  Corporate Author Thesis  
  Publisher Ieee-Inst Electrical Electronics Engineers Inc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (up) 0018-9499 ISBN Medium  
  Area Expedition Conference  
  Notes ISI:000283440400007 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ elepoucu @ Serial 349  
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Author Tetrault, M.A.; Oliver, J.F.; Bergeron, M.; Lecomte, R.; Fontaine, R. doi  openurl
  Title Real Time Coincidence Detection Engine for High Count Rate Timestamp Based PET Type Journal Article
  Year 2010 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.  
  Volume 57 Issue 1 Pages 117-124  
  Keywords Coincidence detection; Positron Emission Tomography (PET)  
  Abstract Coincidence engines follow two main implementation flows: timestamp based systems and AND-gate based systems. The latter have been more widespread in recent years because of its lower cost and high efficiency. However, they are highly dependent on the selected electronic components, they have limited flexibility once assembled and they are customized to fit a specific scanner's geometry. Timestamp based systems are gathering more attention lately, especially with high channel count fully digital systems. These new systems must however cope with important singles count rates. One option is to record every detected event and postpone coincidence detection offline. For daily use systems, a real time engine is preferable because it dramatically reduces data volume and hence image preprocessing time and raw data management. This paper presents the timestamp based coincidence engine for the LabPET(TM), a small animal PET scanner with up to 4608 individual readout avalanche photodiode channels. The engine can handle up to 100 million single events per second and has extensive flexibility because it resides in programmable logic devices. It can be adapted for any detector geometry or channel count, can be ported to newer, faster programmable devices and can have extra modules added to take advantage of scanner-specific features. Finally, the user can select between full processing mode for imaging protocols and minimum processing mode to study different approaches for coincidence detection with offline software.  
  Address [Tetrault, M. -A.; Fontaine, R.] Univ Sherbrooke, Dept Elect & Comp Engn, Sherbrooke, PQ J1K 2R1, Canada, Email: Marc-Andre.Tetrault@USherbrooke.ca  
  Corporate Author Thesis  
  Publisher Ieee-Inst Electrical Electronics Engineers Inc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (up) 0018-9499 ISBN Medium  
  Area Expedition Conference  
  Notes ISI:000274391000016 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ elepoucu @ Serial 500  
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