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Author |
Decoster, S.; Cottenier, S.; Wahl, U.; Correia, J.G.; Pereira, L.M.C.; Lacasta, C.; Da Silva, M.R.; Vantomme, A. |
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Title |
Diluted manganese on the bond-centered site in germanium |
Type |
Journal Article |
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Year |
2010 |
Publication |
Applied Physics Letters |
Abbreviated Journal |
Appl. Phys. Lett. |
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Volume |
97 |
Issue |
15 |
Pages |
151914 - 3pp |
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Abstract |
The functional properties of Mn-doped Ge depend to large extent on the lattice location of the Mn impurities. Here, we present a lattice location study of implanted diluted Mn by means of electron emission channeling. Surprisingly, in addition to the expected substitutional lattice position, a large fraction of the Mn impurities occupies the bond-centered site. Corroborated by ab initio calculations, the bond-centered Mn is related to Mn-vacancy complexes. These unexpected results call for a reassessment of the theoretical studies on the electrical and magnetic behavior of Mn-doped Ge, hereby including the possible role of Mn-vacancy complexes. |
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Address |
[Decoster, S.; Pereira, L. M. C.; Vantomme, A.] Katholieke Univ Leuven, Inst Kern & Stralingsfys, B-3001 Louvain, Belgium, Email: stefan.decoster@fys.kuleuven.be |
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Publisher |
Amer Inst Physics |
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English |
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ISSN |
0003-6951 |
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Notes |
ISI:000283216900030 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
357 |
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Permanent link to this record |
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Author |
Peris, J.B.; Davis, P.; Cuevas, J.M.; Nebot, M.; Sanjuan, R. |
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Title |
Distribution of Fitness Effects Caused by Single-Nucleotide Substitutions in Bacteriophage f1 |
Type |
Journal Article |
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Year |
2010 |
Publication |
Genetics |
Abbreviated Journal |
Genetics |
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Volume |
185 |
Issue |
2 |
Pages |
603-U308 |
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Abstract |
Empirical knowledge of the fitness effects of mutations is important for understanding many evolutionary processes, yet this knowledge is often hampered by several sources of measurement error and bias. Most of these problems can be solved using site-directed mutagenesis to engineer single mutations, an approach particularly suited for viruses due to their small genomes. Here, we used this technique to measure the fitness effect of 100 single-nucleotide substitutions in the bacteriophage f1, a filamentous single-strand DNA virus. We found that approximately one-fifth of all mutations are lethal. Viable ones reduced fitness by 11% on average and were accurately described by a log-normal distribution. More than 90% of synonymous substitutions were selectively neutral, while those affecting intergenic regions reduced fitness by 14% on average. Mutations leading to amino acid substitutions had an overall mean deleterious effect of 37%, which increased to 45% for those changing the amino acid polarity. Interestingly, mutations affecting early steps of the infection cycle tended to be more deleterious than those affecting late steps. Finally, we observed at least two beneficial mutations. Our results confirm that high mutational sensitivity is a general property of viruses with small genomes, including RNA and single-strand DNA viruses infecting animals, plants, and bacteria. |
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Address |
[Peris, Joan B.; Davis, Paulina; Cuevas, Jose M.; Sanjuan, Rafael] Univ Valencia, Inst Cavanilles Biodiversitat & Biol Evolut, Valencia 46980, Spain, Email: rafael.sanjuan@uv.es |
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Genetics Soc Am |
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English |
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ISSN |
0016-6731 |
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Notes |
ISI:000281905200017 |
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no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ elepoucu @ |
Serial |
383 |
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Author |
Bouhova-Thacker, E.; Kostyukhin, V.; Koffas, T.; Liebig, W.; Limper, M.; Piacquadio, G.N.; Prokofiev, K.; Weiser, C.; Wildauer, A. |
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Title |
Expected Performance of Vertex Reconstruction in the ATLAS Experiment at the LHC |
Type |
Journal Article |
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Year |
2010 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
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Volume |
57 |
Issue |
2 |
Pages |
760-767 |
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Keywords |
Data analysis; data reconstruction; high energy physics; pattern recognition; reconstruction algorithms; tracking; vertex detectors |
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Abstract |
In the harsh environment of the Large Hadron Collider at CERN (design luminosity of 10(34) cm(-2) s(-1)) efficient reconstruction of vertices is crucial for many physics analyses. Described in this paper is the expected performance of the vertex reconstruction used in the ATLAS experiment. The algorithms for the reconstruction of primary and secondary vertices as well as for finding photon conversions and vertex reconstruction in jets are described. The implementation of vertex algorithms which follows a very modular design based on object-oriented C++ is presented. A user-friendly concept allows event reconstruction and physics analyses to compare and optimize their choice among different vertex reconstruction strategies. The performance of implemented algorithms has been studied on a variety of Monte Carlo samples and results are presented. |
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Address |
[Bouhova-Thacker, Eva] Univ Lancaster, Lancaster LA1 4YB, England, Email: bouhova@mail.cern.ch |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
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English |
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Edition |
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ISSN |
0018-9499 |
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Expedition |
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Conference |
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Notes |
ISI:000276679200006 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
260 |
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Permanent link to this record |
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Author |
Belver, D.; Cabanelas, P.; Castro, E.; Garzon, J.A.; Gil, A.; Gonzalez-Diaz, D.; Koenig, W.; Traxler, M. |
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Title |
Performance of the Low-Jitter High-Gain/Bandwidth Front-End Electronics of the HADES tRPC Wall |
Type |
Journal Article |
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Year |
2010 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
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Volume |
57 |
Issue |
5 |
Pages |
2848-2856 |
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Keywords |
Charge to width algorithm; fast amplifying and digitizing electronics; front-end electronics; HADES; time of flight; timing RPC |
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Abstract |
A front-end electronics (FEE) chain for accurate time measurements has been developed for the new Resistive Plate Chamber (RPC)-based Time-of-Flight (TOF) wall of the High Acceptance Di-Electron Spectrometer (HADES). The wall covers an area of around 8 m(2) divided in 6 sectors. In total, 1122 4-gap timing RPC cells are read-out by 2244 time and charge sensitive channels. The FEE chain consists of 2 custom-made boards: a 4-channel Daughter BOard(DBO) and a 32-channel MotherBOard (MBO). The DBO uses a fast 2 GHz amplifier feeding a dual high-speed discriminator. The time and charge information are encoded, respectively, in the leading edge and the width of an LVDS signal. Each MBO houses up to 8 DBOs providing them regulated voltage supply, threshold values via DACs, test signals and, additionally, routing out a signal proportional to the channel multiplicity needed for a 1st level trigger decision. The MBO delivers LVDS signals to a multi-purpose Trigger Readout Board (TRB) for data acquisition. The FEE allows achieving a system resolution around 75 ps fulfilling comfortably the requirements of the HADES upgrade [1]. The commissioning of the whole RPC wall is finished and the 6 sectors are already mounted in their final position in the HADES spectrometer and ready to take data during the beam-times foreseen for 2010. |
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Address |
[Belver, Daniel; Cabanelas, P.; Castro, E.; Garzon, J. A.] Univ Santiago Compostela, LabCAF, Santiago De Compostela 15782, Spain, Email: daniel.belver@usc.es |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
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Language |
English |
Summary Language |
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ISSN |
0018-9499 |
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Expedition |
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Conference |
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Notes |
ISI:000283440400007 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
349 |
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Permanent link to this record |
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Author |
Tetrault, M.A.; Oliver, J.F.; Bergeron, M.; Lecomte, R.; Fontaine, R. |
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Title |
Real Time Coincidence Detection Engine for High Count Rate Timestamp Based PET |
Type |
Journal Article |
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Year |
2010 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
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Volume |
57 |
Issue |
1 |
Pages |
117-124 |
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Keywords |
Coincidence detection; Positron Emission Tomography (PET) |
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Abstract |
Coincidence engines follow two main implementation flows: timestamp based systems and AND-gate based systems. The latter have been more widespread in recent years because of its lower cost and high efficiency. However, they are highly dependent on the selected electronic components, they have limited flexibility once assembled and they are customized to fit a specific scanner's geometry. Timestamp based systems are gathering more attention lately, especially with high channel count fully digital systems. These new systems must however cope with important singles count rates. One option is to record every detected event and postpone coincidence detection offline. For daily use systems, a real time engine is preferable because it dramatically reduces data volume and hence image preprocessing time and raw data management. This paper presents the timestamp based coincidence engine for the LabPET(TM), a small animal PET scanner with up to 4608 individual readout avalanche photodiode channels. The engine can handle up to 100 million single events per second and has extensive flexibility because it resides in programmable logic devices. It can be adapted for any detector geometry or channel count, can be ported to newer, faster programmable devices and can have extra modules added to take advantage of scanner-specific features. Finally, the user can select between full processing mode for imaging protocols and minimum processing mode to study different approaches for coincidence detection with offline software. |
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Address |
[Tetrault, M. -A.; Fontaine, R.] Univ Sherbrooke, Dept Elect & Comp Engn, Sherbrooke, PQ J1K 2R1, Canada, Email: Marc-Andre.Tetrault@USherbrooke.ca |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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ISSN |
0018-9499 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000274391000016 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
500 |
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Permanent link to this record |
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Author |
Sanjuan, R.; Nebot, M.; Chirico, N.; Mansky, L.M.; Belshaw, R. |
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Title |
Viral Mutation Rates |
Type |
Journal Article |
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Year |
2010 |
Publication |
Journal of Virology |
Abbreviated Journal |
J. Virol. |
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Volume |
84 |
Issue |
19 |
Pages |
9733-9748 |
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Keywords |
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Abstract |
Accurate estimates of virus mutation rates are important to understand the evolution of the viruses and to combat them. However, methods of estimation are varied and often complex. Here, we critically review over 40 original studies and establish criteria to facilitate comparative analyses. The mutation rates of 23 viruses are presented as substitutions per nucleotide per cell infection (s/n/c) and corrected for selection bias where necessary, using a new statistical method. The resulting rates range from 10(-8) to 10(-6) s/n/c for DNA viruses and from 10(-6) to 10(-4) s/n/c for RNA viruses. Similar to what has been shown previously for DNA viruses, there appears to be a negative correlation between mutation rate and genome size among RNA viruses, but this result requires further experimental testing. Contrary to some suggestions, the mutation rate of retroviruses is not lower than that of other RNA viruses. We also show that nucleotide substitutions are on average four times more common than insertions/deletions (indels). Finally, we provide estimates of the mutation rate per nucleotide per strand copying, which tends to be lower than that per cell infection because some viruses undergo several rounds of copying per cell, particularly double-stranded DNA viruses. A regularly updated virus mutation rate data set will be available at www.uv.es/rsanjuan/virmut. |
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Address |
[Sanjuan, Rafael] Univ Valencia, Inst Cavanilles Biodiversitat & Biol Evolutiva, Dept Genet, Valencia 46980, Spain, Email: rafael.sanjuan@uv.es |
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Publisher |
Amer Soc Microbiology |
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English |
Summary Language |
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ISSN |
0022-538x |
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Conference |
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Notes |
ISI:000282641800008 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
371 |
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Permanent link to this record |
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Author |
MiniBooNE Collaboration (Aguilar-Arevalo, A.A. et al); Sorel, M. |
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Title |
Event Excess in the MiniBooNE Search for (nu)over-bar(mu) -> (nu)over-bar(e) Oscillations |
Type |
Journal Article |
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Year |
2010 |
Publication |
Physical Review Letters |
Abbreviated Journal |
Phys. Rev. Lett. |
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Volume |
105 |
Issue |
18 |
Pages |
181801 - 5pp |
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Keywords |
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Abstract |
The MiniBooNE experiment at Fermilab reports results from a search for (nu) over bar (mu) -> (nu) over bar (e) oscillations, using a data sample corresponding to 5.66 x 10(20) protons on target. An excess of 20.9 +/- 14.0 events is observed in the energy range 475 < E-nu(QE) < 1250 MeV, which, when constrained by the observed <(nu)over bar>(mu) events, has a probability for consistency with the background-only hypothesis of 0.5%. On the other hand, fitting for (nu) over bar (mu) -> (nu) over bar (e) oscillations, the best-fit point has chi(2) probability of 8.7%. The data are consistent with (nu) over bar (mu) -> (nu) over bar (e) oscillations in the 0.1 to 1.0 eV(2) Delta m(2) range and with the evidence for antineutrino oscillations from the Liquid Scintillator Neutrino Detector at Los Alamos National Laboratory. |
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Address |
[Dharmapalan, R.; Perevalov, D.; Stancu, I.] Univ Alabama, Tuscaloosa, AL 35487 USA |
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Publisher |
Amer Physical Soc |
Place of Publication |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Issue |
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ISSN |
0031-9007 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000283492000002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
263 |
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Permanent link to this record |
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Author |
CDF Collaboration (Aaltonen, T. et al); Cabrera, S. |
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Title |
Search for R-Parity Violating Decays of Sneutrinos to e mu, μtau, and e tau Pairs in p(p)over-bar Collisions at root s=1.96 TeV |
Type |
Journal Article |
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Year |
2010 |
Publication |
Physical Review Letters |
Abbreviated Journal |
Phys. Rev. Lett. |
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Volume |
105 |
Issue |
19 |
Pages |
191801 - 7pp |
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Keywords |
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Abstract |
We present a search for supersymmetric neutrino (nu) over tilde production using the Tevatron p (p) over bar collision data collected with the CDF II detector and corresponding to an integrated luminosity of 1 fb(-1). We focus on the scenarios predicted by the R-parity violating (RPV) supersymmetric models in which sneutrinos decay to two charged leptons of different flavor. With the data consistent with the standard model expectations, we set upper limits on sigma(p (p) over bar -> (nu) over tilde) BR((nu) over tilde -> e mu, μtau, e tau) and use these results to constrain the RPV couplings as a function of the sneutrino mass. |
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Address |
[Aaltonen, T.; Mehtala, P.; Orava, R.; Osterberg, K.; Saarikko, H.; van Remortel, N.] Univ Helsinki, Dept Phys, Div High Energy Phys, FIN-00014 Helsinki, Finland |
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Publisher |
Amer Physical Soc |
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English |
Summary Language |
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Series Volume |
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Edition |
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ISSN |
0031-9007 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000283849300004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
267 |
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Permanent link to this record |
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Author |
Wu, J.J.; Molina, R.; Oset, E.; Zou, B.S. |
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Title |
Prediction of Narrow N* and Lambda* Resonances with Hidden Charm above 4 GeV |
Type |
Journal Article |
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Year |
2010 |
Publication |
Physical Review Letters |
Abbreviated Journal |
Phys. Rev. Lett. |
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Volume |
105 |
Issue |
23 |
Pages |
232001 - 4pp |
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Keywords |
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Abstract |
The interaction between various charmed mesons and charmed baryons is studied within the framework of the coupled-channel unitary approach with the local hidden gauge formalism. Several meson-baryon dynamically generated narrow N* and Lambda* resonances with hidden charm are predicted with mass above 4 GeV and width smaller than 100 MeV. The predicted new resonances definitely cannot be accommodated by quark models with three constituent quarks and can be looked for in the forthcoming PANDA/FAIR experiments. |
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Address |
[Wu, Jia-Jun; Zou, B. S.] CAS, Inst High Energy Phys, Beijing 100049, Peoples R China |
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Publisher |
Amer Physical Soc |
Place of Publication |
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English |
Summary Language |
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Series Issue |
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ISSN |
0031-9007 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000286731400003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
526 |
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Permanent link to this record |
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Author |
BABAR Collaboration (del Amo Sanchez, P. et al); Lopez-March, N.; Martinez-Vidal, F.; Milanes, D.A.; Oyanguren, A. |
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Title |
Measurement of D-0-(D)over-bar(0) Mixing Parameters Using D-0 -> K-S(0)pi(+) pi(-) and D-0 -> (KSK+K-)-K-0 Decays |
Type |
Journal Article |
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Year |
2010 |
Publication |
Physical Review Letters |
Abbreviated Journal |
Phys. Rev. Lett. |
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Volume |
105 |
Issue |
8 |
Pages |
081803 - 7pp |
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Keywords |
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Abstract |
We report a direct measurement of D-0-(D) over bar (0) mixing parameters through a time-dependent amplitude analysis of the Dalitz plots of D-0 -> K-S(0)pi(+)pi(-) and, for the first time, D-0 -> (KSK+K-)-K-0 decays. The low-momentum pion pi(+)(s) in the decay D*(+) -> D-0 pi(+)(s) identifies the flavor of the neutral D meson at its production. Using 468.5 fb(-1) of e(+)e(-) colliding-beam data recorded near root s = 10.6 by the BABAR detector at the PEP-II asymmetric-energy collider at SLAC, we measure the mixing parameters x = [1.6 + 2.3(stat) +/- 1.2(syst) +/- 0.8(model)] X 10(-3), and y = [5.7 +/- 2.0(stat) +/- 1.3(syst) +/- 0.7(model)] X 10(-3). These results provide the best measurement to date of x and y. The knowledge of the value of x, in particular, is crucial for understanding the origin of mixing. |
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Address |
[Sanchez, P. del Amo; Lees, J. P.; Poireau, V.; Prencipe, E.; Tisserand, V.] Univ Savoie, CNRS, Lab Annecy le Vieux Phys Particules LAPP, IN2P3, F-74941 Annecy Le Vieux, France |
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Publisher |
Amer Physical Soc |
Place of Publication |
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English |
Summary Language |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9007 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000281071800003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
391 |
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Permanent link to this record |