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Author |
Baran, J. et al; Brzezinski, K. |
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Title |
Feasibility of the J-PET to monitor the range of therapeutic proton beams |
Type |
Journal Article |
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Year  |
2024 |
Publication |
Physica Medica |
Abbreviated Journal |
Phys. Medica |
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Volume |
118 |
Issue |
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Pages |
103301 - 9pp |
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Keywords |
PET; Range monitoring; J-PET; Monte Carlo simulations; Proton radiotherapy |
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Abstract |
Purpose: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J -PET) scanner for intra-treatment proton beam range monitoring. Methods: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J -PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread -Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J -PET scanner prototype dedicated to the proton beam range assessment. Results: The investigations indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10-5 coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple -layer dual -head geometry. The results indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for the clinical application, Conclusions: We performed simulation studies demonstrating that the feasibility of the J -PET detector for PET -based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre -clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double -layer cylindrical and triple -layer dual -head J -PET geometry configurations seem promising for future clinical application. |
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Address |
[Baran, Jakub; Silarski, Michal; Chug, Neha; Coussat, Aurelien; Czerwinski, Eryk; Dadgar, Meysam; Dulski, Kamil; Eliyan, Kavya, V; Gajos, Aleksander; Kacprzak, Krzysztof; Kaplon, Lukasz; Korcyl, Grzegorz; Kozik, Tomasz; Kumar, Deepak; Niedzwiecki, Szymon; Panek, Dominik; Parzych, Szymon; del Rio, Elena Perez; Simbarashe, Moyo; Sharma, Sushil; Shivani; Skurzok, Magdalena; Stepien, Ewa L.; Tayefi, Keyvan; Tayefi, Faranak; Moskal, Pawel] Jagiellonian Univ, Fac Phys Astron & Appl Comp Sci, 11 Lojasiewicza St, PL-30348 Krakow, Poland, Email: jakubbaran92@gmail.com |
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Publisher |
Elsevier Sci Ltd |
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English |
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ISSN |
1120-1797 |
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Notes |
WOS:001178648400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5990 |
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Author |
Fajfer, S.; Solomonidi, E.; Vale Silva, L. |
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Title |
S-wave contribution to rare D0 → π+ π- l+ l- decays in the standard model and sensitivity to new physics |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
109 |
Issue |
3 |
Pages |
036027 - 24pp |
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Keywords |
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Abstract |
Physics of the up-type flavor offers unique possibilities of testing the standard model (SM) compared to the down-type flavor sector. Here, we discuss SM and new physics (NP) contributions to the rare charmmeson decay D0 -> x+x- l+l-. In particular, we discuss the effect of including the lightest scalar isoscalar resonance in the SM picture, namely, the f0(500), which manifests in a big portion of the allowed phase space. Other than showing in the total branching ratio at an observable level of about 20%, the f0(500) resonance manifests as interference terms with the vector resonances, such as at high invariant mass of the leptonic pair in distinct angular observables. Recent data from LHCb optimize the sensitivity to P-wave contributions that we analyze in view of the inclusion of vector resonances. We propose the measurement of alternative observables that are sensitive to the S-wave and are straightforward to implement experimentally. This leads to a new set of null observables that vanish in the SM due to its gauge and flavor structures. Finally, we study observables that depend on the SM interference with generic NP contributions from semileptonic four-fermion operators in the presence of the S-wave. |
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Address |
[Fajfer, Svjetlana] Jozef Stefan Inst, Jamova 39,POB 3000, Ljubljana 1001, Slovenia |
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Publisher |
Amer Physical Soc |
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English |
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Edition |
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ISSN |
2470-0010 |
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Conference |
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Notes |
WOS:001181678500001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5991 |
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Author |
Alexandre, J.; Mavromatos, N.E.; Mitsou, V.A.; Musumeci, E. |
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Title |
Resummation schemes for high-electric-charge objects leading to improved experimental mass limits |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
109 |
Issue |
3 |
Pages |
036026 - 20pp |
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Keywords |
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Abstract |
High-electric-charge compact objects (HECOs) appear in several theoretical particle physics models beyond the Standard Model, and are actively searched for in current colliders, such as the Large Hadron Collider at CERN. In such searches, mass bounds of these objects have been placed, using Drell-Yan and photon-fusion processes at tree level so far. However, such mass-bound estimates are not reliable, given that, as a result of the large values of the electric charge of the HECO, perturbative quantum electrodynamics calculations break down. In this work, we perform a Dyson-Schwinger resummation scheme (as opposed to lattice strong-coupling approach), which makes the computation of the pertinent HECO-production cross sections reliable, thus allowing us to extract improved mass bounds for such objects from ATLAS and MoEDAL searches. |
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Address |
[Alexandre, Jean; Mavromatos, Nick E.] Kings Coll London, Dept Phys, Theoret Particle Phys & Cosmol Grp, London WC2R 2LS, England, Email: jean.alexandre@kcl.ac.uk; |
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Amer Physical Soc |
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English |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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ISSN |
2470-0010 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:001181678500003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5995 |
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Author |
ANTARES Collaboration (Albert, A. et al); Alves, S.; Calvo, D.; Carretero, V.; Gozzini, R.; Hernandez-Rey, J.J.; Lazo, A.; Manczak, J.; Real, D.; Sanchez-Losa, A.; Saina, A.; Salesa Greus, F.; Zornoza, J.D.; Zuñiga, J. |
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Title |
Searches for Neutrinos in the Direction of Radio-bright Blazars with the ANTARES Telescope |
Type |
Journal Article |
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Year |
2024 |
Publication |
Astrophysical Journal |
Abbreviated Journal |
Astrophys. J. |
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Volume |
964 |
Issue |
1 |
Pages |
3 - 13pp |
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Keywords |
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Abstract |
Active galaxies, especially blazars, are among the most promising extragalactic candidates for high-energy neutrino sources. To date, ANTARES searches included these objects and used GeV-TeV gamma-ray flux to select blazars. Here, a statistically complete blazar sample selected by their bright radio emission is used as the target for searches of origins of neutrinos collected by the ANTARES neutrino telescope over 13 yr of operation. The hypothesis of a neutrino-blazar directional correlation is tested by pair counting and a complementary likelihood-based approach. The resulting posttrial p-value is 3.0% (2.2 sigma in the two-sided convention). Additionally, a time-dependent analysis is performed to search for temporal clustering of neutrino candidates as a means of detecting neutrino flares in blazars. None of the investigated sources alone reaches a significant flare detection level. However, the presence of 18 sources with a pretrial significance above 3 sigma indicates a p = 1.4% (2.5 sigma in the two-sided convention) detection of a time-variable neutrino flux. An a posteriori investigation reveals an intriguing temporal coincidence of neutrino, radio, and gamma-ray flares of the J0242+1101 blazar at a p = 0.5% (2.9 sigma in the two-sided convention) level. Altogether, the results presented here suggest a possible connection of neutrino candidates detected by the ANTARES telescope with radio-bright blazars. |
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Address |
[Albert, A.; Drouhin, D.; Pradier, T.] Univ Strasbourg, CNRS, UMR 7178, IPHC, F-67000 Strasbourg, France, Email: julien.aublin@apc.in2p3.fr; |
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Publisher |
IOP Publishing Ltd |
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English |
Summary Language |
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Original Title |
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Series Editor |
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ISSN |
0004-637x |
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Notes |
WOS:001183251300001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5996 |
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Author |
LHCb Collaboration (Aaij, R. et al); Jaimes Elles, S.J.; Jashal, B.K.; Martinez-Vidal, F.; Oyanguren, A.; Rebollo De Miguel, M.; Ruiz Vidal, J.; Sanderswood, I.; Zhuo, J. |
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Title |
Measurement of the CKM angle γ in the B0 → D K*0 channel using self-conjugate D → KS0 h+ h- decays |
Type |
Journal Article |
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Year |
2024 |
Publication |
European Physical Journal C |
Abbreviated Journal |
Eur. Phys. J. C |
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Volume |
84 |
Issue |
2 |
Pages |
206 - 18pp |
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Keywords |
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Abstract |
A model-independent study of CP violation in B-0 -> DK (*0) decays is presented using data corresponding to an integrated luminosity of 9 fb(-1) collected by the LHCb experiment at centre-of-mass energies of v s = 7, 8 and 13TeV. The CKM angle. is determined by examining the distributions of signal decays in phase-space bins of the self-conjugate D. K(S)(0)h(+) h(-) decays, where h = p, K. Observables related to CP violation are measured and the angle. is determined to be = (49+22 -19). Measurements of the amplitude ratio and strong-phase difference between the favoured and suppressed B-0 decays are also presented. |
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Address |
[Baptista de Souza Leite, J.; Bediaga, I. B.; Cruz Torres, M.; De Freitas Carneiro Da Graca, U.; De Miranda, J. M.; dos Reis, A. C.; Falcao, L. N.; Gomes, A.; Massafferri, A.; Santoro, L.; Torres Machado, D.] CBPF, Rio De Janeiro, Brazil |
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Corporate Author |
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Thesis |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6044 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001185559300001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5997 |
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