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Author (up) Albiol, A.; Albiol, F.; Paredes, R.; Plasencia-Martinez, J.M.; Blanco Barrio, A.; Garcia Santos, J.M.; Tortajada, S.; Gonzalez Montano, V.M.; Rodriguez Godoy, C.E.; Fernandez Gomez, S.; Oliver-Garcia, E.; de la Iglesia Vaya, M.; Marquez Perez, F.L.; Rayo Madrid, J.I. doi  openurl
  Title A comparison of Covid-19 early detection between convolutional neural networks and radiologists Type Journal Article
  Year 2022 Publication Insights into Imaging Abbreviated Journal Insights Imaging  
  Volume 13 Issue 1 Pages 122 - 12pp  
  Keywords Deep learning; Covid-19; Radiology  
  Abstract Background The role of chest radiography in COVID-19 disease has changed since the beginning of the pandemic from a diagnostic tool when microbiological resources were scarce to a different one focused on detecting and monitoring COVID-19 lung involvement. Using chest radiographs, early detection of the disease is still helpful in resource-poor environments. However, the sensitivity of a chest radiograph for diagnosing COVID-19 is modest, even for expert radiologists. In this paper, the performance of a deep learning algorithm on the first clinical encounter is evaluated and compared with a group of radiologists with different years of experience. Methods The algorithm uses an ensemble of four deep convolutional networks, Ensemble4Covid, trained to detect COVID-19 on frontal chest radiographs. The algorithm was tested using images from the first clinical encounter of positive and negative cases. Its performance was compared with five radiologists on a smaller test subset of patients. The algorithm's performance was also validated using the public dataset COVIDx. Results Compared to the consensus of five radiologists, the Ensemble4Covid model achieved an AUC of 0.85, whereas the radiologists achieved an AUC of 0.71. Compared with other state-of-the-art models, the performance of a single model of our ensemble achieved nonsignificant differences in the public dataset COVIDx. Conclusion The results show that the use of images from the first clinical encounter significantly drops the detection performance of COVID-19. The performance of our Ensemble4Covid under these challenging conditions is considerably higher compared to a consensus of five radiologists. Artificial intelligence can be used for the fast diagnosis of COVID-19.  
  Address [Albiol, Alberto] Univ Politecn Valencia, iTeam Inst, ETSI Telecomunicac, Camino Vera S-N, Valencia 46022, Spain, Email: alalbiol@iteam.upv.es  
  Corporate Author Thesis  
  Publisher Springer Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1869-4101 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000832727200003 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5302  
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Author (up) Blanes-Selva, V.; Ruiz-Garcia, V.; Tortajada, S.; Benedi, J.M.; Valdivieso, B.; Garcia-Gomez, J.M. url  doi
openurl 
  Title Design of 1-year mortality forecast at hospital admission: A machine learning approach Type Journal Article
  Year 2021 Publication Health Informatics Journal Abbreviated Journal Health Inform. J.  
  Volume 27 Issue 1 Pages 13pp  
  Keywords machine learning; palliative care; hospital admission data; mortality forecast  
  Abstract Palliative care is referred to a set of programs for patients that suffer life-limiting illnesses. These programs aim to maximize the quality of life (QoL) for the last stage of life. They are currently based on clinical evaluation of the risk of 1-year mortality. The main aim of this work is to develop and validate machine-learning-based models to predict the exitus of a patient within the next year using data gathered at hospital admission. Five machine-learning techniques were applied using a retrospective dataset. The evaluation was performed with five metrics computed by a resampling strategy: Accuracy, the area under the ROC curve, Specificity, Sensitivity, and the Balanced Error Rate. All models reported an AUC ROC from 0.857 to 0.91. Specifically, Gradient Boosting Classifier was the best model, producing an AUC ROC of 0.91, a sensitivity of 0.858, a specificity of 0.808, and a BER of 0.1687. Information from standard procedures at hospital admission combined with machine learning techniques produced models with competitive discriminative power. Our models reach the best results reported in the state of the art. These results demonstrate that they can be used as an accurate data-driven palliative care criteria inclusion.  
  Address [Blanes-Selva, Vicent; Benedi, Jose-Miguel; Garcia-Gomez, Juan M.] Univ Politecn Valencia, Valencia, Spain, Email: viblasel@upv.es  
  Corporate Author Thesis  
  Publisher Sage Publications Inc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1460-4582 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000645567000008 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5182  
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Author (up) Carrasco-Ribelles, L.A.; Pardo-Mas, J.R.; Tortajada, S.; Saez, C.; Valdivieso, B.; Garcia-Gomez, J.M. doi  openurl
  Title Predicting morbidity by local similarities in multi-scale patient trajectories Type Journal Article
  Year 2021 Publication Journal of Biomedical Informatics Abbreviated Journal J. Biomed. Inform.  
  Volume 120 Issue Pages 103837 - 9pp  
  Keywords Patient trajectory; Risk prediction; Local alignment; Dynamic programming; Diabetes; Cardiovascular disease  
  Abstract Patient Trajectories (PTs) are a method of representing the temporal evolution of patients. They can include information from different sources and be used in socio-medical or clinical domains. PTs have generally been used to generate and study the most common trajectories in, for instance, the development of a disease. On the other hand, healthcare predictive models generally rely on static snapshots of patient information. Only a few works about prediction in healthcare have been found that use PTs, and therefore benefit from their temporal dimension. All of them, however, have used PTs created from single-source information. Therefore, the use of longitudinal multi-scale data to build PTs and use them to obtain predictions about health conditions is yet to be explored. Our hypothesis is that local similarities on small chunks of PTs can identify similar patients concerning their future morbidities. The objectives of this work are (1) to develop a methodology to identify local similarities between PTs before the occurrence of morbidities to predict these on new query individuals; and (2) to validate this methodology on risk prediction of cardiovascular diseases (CVD) occurrence in patients with diabetes. We have proposed a novel formal definition of PTs based on sequences of longitudinal multi-scale data. Moreover, a dynamic programming methodology to identify local alignments on PTs for predicting future morbidities is proposed. Both the proposed methodology for PT definition and the alignment algorithm are generic to be applied on any clinical domain. We validated this solution for predicting CVD in patients with diabetes and we achieved a precision of 0.33, a recall of 0.72 and a specificity of 0.38. Therefore, the proposed solution in the diabetes use case can result of utmost utility to secondary screening.  
  Address [Carrasco-Ribelles, Lucia A.; Pardo-Mas, Jose Ramon; Saez, Carlos; Garcia-Gomez, Juan M.] Univ Politecn Valencia, Biomed Data Sci Lab BDSLAB, Inst Tecnol Informat & Comunicac ITACA, Camino Vera S-N, Valencia 46022, Spain, Email: lucarri@etsii.upv.es;  
  Corporate Author Thesis  
  Publisher Academic Press Inc Elsevier Science Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1532-0464 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000683527500003 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 4934  
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Author (up) Oliver, J.F.; Fuster-Garcia, E.; Cabello, J.; Tortajada, S.; Rafecas, M. doi  openurl
  Title Application of Artificial Neural Network for Reducing Random Coincidences in PET Type Journal Article
  Year 2013 Publication IEEE Transactions on Nuclear Science Abbreviated Journal IEEE Trans. Nucl. Sci.  
  Volume 60 Issue 5 Pages 3399-3409  
  Keywords  
  Abstract Positron Emission Tomography (PET) is based on the detection in coincidence of the two photons created in a positron annihilation. In conventional PET, this coincidence identification is usually carried out through a coincidence electronic unit. An accidental coincidence occurs when two photons arising from different annihilations are classified as a coincidence. Accidental coincidences are one of the main sources of image degradation in PET. Some novel systems allow coincidences to be selected post-acquisition in software, or in real time through a digital coincidence engine in an FPGA. These approaches provide the user with extra flexibility in the sorting process and allow the application of alternative coincidence sorting procedures. In this work a novel sorting procedure based on Artificial Neural Network (ANN) techniques has been developed. It has been compared to a conventional coincidence sorting algorithm based on a time coincidence window. The data have been obtained from Monte-Carlo simulations. A small animal PET scanner has been implemented to this end. The efficiency (the ratio of correct identifications) can be selected for both methods. In one case by changing the actual value of the coincidence window used, and in the other by changing a threshold at the output of the neural network. At matched efficiencies, the ANN-based method always produces a sorted output with a smaller random fraction. In addition, two differential trends are found: the conventional method presents a maximum achievable efficiency, while the ANN-based method is able to increase the efficiency up to unity, the ideal value, at the cost of increasing the random fraction. Images reconstructed using ANN sorted data (no compensation for randoms) present better contrast, and those image features which are more affected by randoms are enhanced. For the image quality phantom used in the paper, the ANN method decreases the spill-over ratio by a factor of 18%.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0018-9499 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000325827200027 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1611  
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Author (up) Tortajada, S.; Albiol, F.; Caballero, L.; Albiol, A.; Leganes-Nieto, J.L. doi  openurl
  Title A portable geometry-independent tomographic system for gamma-ray, a next generation of nuclear waste characterization Type Journal Article
  Year 2023 Publication Scientific Reports Abbreviated Journal Sci Rep  
  Volume 13 Issue 1 Pages 12284 - 10pp  
  Keywords  
  Abstract One of the main activities of the nuclear industry is the characterisation of radioactive waste based on the detection of gamma radiation. Large volumes of radioactive waste are classified according to their average activity, but often the radioactivity exceeds the maximum allowed by regulators in specific parts of the bulk. In addition, the detection of the radiation is currently based on static detection systems where the geometry of the bulk is fixed and well known. Furthermore, these systems are not portable and depend on the transport of waste to the places where the detection systems are located. However, there are situations where the geometry varies and where moving waste is complex. This is especially true in compromised situations.We present a new model for nuclear waste management based on a portable and geometry-independent tomographic system for three-dimensional image reconstruction for gamma radiation detection. The system relies on a combination of a gamma radiation camera and a visible camera that allows to visualise radioactivity using augmented reality and artificial computer vision techniques. This novel tomographic system has the potential to be a disruptive innovation in the nuclear industry for nuclear waste management.  
  Address [Tortajada, Salvador; Albiol, Francisco; Caballero, Luis] Univ Valencia, CSIC, Inst Fis Corpuscular, E-46980 Paterna Valencia, Spain, Email: s.tortajada@ific.uv.es  
  Corporate Author Thesis  
  Publisher Nature Portfolio Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2045-2322 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001041587900052 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5612  
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