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Author Martin-Luna, P.; Esperante, D.; Prieto, A.F.; Fuster-Martinez, N.; Rivas, I.G.; Gimeno, B.; Ginestar, D.; Gonzalez-Iglesias, D.; Hueso, J.L.; Llosa, G.; Martinez-Reviriego, P.; Meneses-Felipe, A.; Riera, J.; Regueiro, P.V.; Hueso-Gonzalez, F. doi  openurl
  Title Simulation of electron transport and secondary emission in a photomultiplier tube and validation Type Journal Article
  Year 2024 Publication Sensors and Actuators A-Physical Abbreviated Journal Sens. Actuator A-Phys.  
  Volume 365 Issue Pages 114859 - 10pp  
  Keywords Photomultiplier tube; Photodetector; Proton therapy; Monte Carlo simulation; Measurement  
  Abstract The electron amplification and transport within a photomultiplier tube (PMT) has been investigated by developing an in-house Monte Carlo simulation code. The secondary electron emission in the dynodes is implemented via an effective electron model and the Modified Vaughan's model, whereas the transport is computed with the Boris leapfrog algorithm. The PMT gain, rise time and transit time have been studied as a function of supply voltage and external magnetostatic field. A good agreement with experimental measurements using a Hamamatsu R13408-100 PMT was obtained. The simulations have been conducted following different treatments of the underlying geometry: three-dimensional, two-dimensional and intermediate (2.5D). The validity of these approaches is compared. The developed framework will help in understanding the behavior of PMTs under highly intense and irregular illumination or varying external magnetic fields, as in the case of prompt gamma-ray measurements during pencil-beam proton therapy; and aid in optimizing the design of voltage dividers with behavioral circuit models.  
  Address [Martin-Luna, Pablo; Esperante, Daniel; Fuster-Martinez, Nuria; Gimeno, Benito; Gonzalez-Iglesias, Daniel; Llosa, Gabriela; Martinez-Reviriego, Pablo; Meneses-Felipe, Alba; Hueso-Gonzalez, Fernando] CSIC UV, Inst Fis Corpuscular IFIC, C Catedrat Jose Beltran 2, Paterna 46980, Spain, Email: pablo.martin@uv.es  
  Corporate Author Thesis  
  Publisher Elsevier Science Sa Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (up) 0924-4247 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001131902700001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5876  
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Author Migueis, F.; Casaña, J.V.; Garcia-Fernandez, D.; Hueso-Gonzalez, F.; Llosa, G.; Prieto, A.F.; Regueiro, P.V.; Rivas, I.G.; Ros, A.; Crespo, P.; Simoes, H. doi  openurl
  Title Sensitivity of coaxial prompt gamma-ray monitoring in heterogeneous geometries: A Monte Carlo simulation study Type Journal Article
  Year 2025 Publication Radiation Physics and Chemistry Abbreviated Journal Radiat. Phys. Chem.  
  Volume 232 Issue Pages 112639 - 11pp  
  Keywords Protons; Coaxial; Proton therapy; Prompt gamma rays; Monte Carlo; Range verification  
  Abstract Proton beams offer significant advantages over conventional radiotherapy due to their unique interaction with matter. Specifically, the ionization density caused by these beams is higher in a well-defined region (the Bragg peak) with a sharp decline in intensity beyond a specific depth. However, variations in proton range – often caused by changes in patient anatomy and morphology during treatment – can introduce uncertainties in dose distribution. To account for this, clinicians apply conservative margins, which limit the full potential of proton therapy. Efforts have been focused on developing proton range and dose distribution monitoring systems to reduce the need for large safety margins. These systems are based on detecting and analyzing the byproducts that result from the interaction between the proton beams and tissue. In this article, we focused specifically on a system that aims to detect photons called prompt gamma (PG) rays. We conducted Monte Carlo simulations of proton beams interacting with anthropomorphic phantoms of varying densities to simulate morphological changes. A single scintillation detector was positioned coaxially with the beam and behind the phantom to capture the emitted PG rays in each scenario. Our analysis focused on discrepancies in proton range that resulted from irradiating an anthropomorphic head phantom with varying brain tissue densities and detecting secondary particles resulting from these interactions. We observed potential correlations between gamma-ray signatures and variations in proton range and energy deposition, suggesting that this monitoring technique could be effective for real-world clinical applications.  
  Address [Migueis, F.; Crespo, P.; Simoes, H.] Lab Instrumentat Expt Particle Phys, Coimbra, Portugal, Email: fmemf@student.uc.pt  
  Corporate Author Thesis  
  Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (up) 0969-806x ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001448817200001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 6567  
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