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Author  |
Amaldi, U.; Bonomi, R.; Braccini, S.; Crescenti, M.; Degiovanni, A.; Garlasche, M.; Garonna, A.; Magrin, G.; Mellace, C.; Pearce, P.; Pitta, G.; Puggioni, P.; Rosso, E.; Verdu-Andres, S.; Wegner, R.; Weiss, M.; Zennaro, R. |
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Title |
Accelerators for hadrontherapy: From Lawrence cyclotrons to linacs |
Type |
Journal Article |
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Year |
2010 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
620 |
Issue |
2-3 |
Pages |
563-577 |
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Keywords |
Medical accelerators; Linac; Cyclotron; Synchrotron; Cyclinac; Radiation oncology; Hadrontherapy; Particle therapy; Proton therapy; Carbon ion therapy; Dose delivery |
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Abstract |
Hadrontherapy with protons and carbon ions is a fast developing methodology in radiation oncology. The accelerators used and planned for this purpose are reviewed starting from the cyclotrons used in the thirties. As discussed in the first part of this paper, normal and superconducting cyclotrons are still employed, together with synchrotrons, for proton therapy while for carbon ion therapy synchrotrons have been till now the only option. The latest developments concern a superconducting cyclotron for carbon ion therapy, fast-cycling high frequency linacs and 'single room' proton therapy facilities. These issues are discussed in the second part of the paper by underlining the present challenges, in particular the treatment of moving organs. |
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Address |
[Amaldi, U.; Bonomi, R.; Braccini, S.; Crescenti, M.; Degiovanni, A.; Garlasche, M.; Garonna, A.; Magrin, G.; Mellace, C.; Pearce, P.; Pitta, G.; Puggioni, P.; Rosso, E.; Andres, S. Verdu; Wegner, R.; Weiss, M.; Zennaro, R.] TERA Fdn, Novara, Italy, Email: Saverio.Braccini@cern.ch |
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Publisher |
Elsevier Science Bv |
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Language |
English |
Summary Language |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Conference |
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Notes |
ISI:000280601700058 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
401 |
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Author |
Degiovanni, A.; Amaldi, U.; Bonomi, R.; Garlasche, M.; Garonna, A.; Verdu-Andres, S.; Wegner, R. |
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Title |
TERA high gradient test program of RF cavities for medical linear accelerators |
Type |
Journal Article |
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Year |
2011 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
657 |
Issue |
1 |
Pages |
55-58 |
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Keywords |
Medical accelerators; Hadrontherapy; Cyclinac; Linac; RF cavity; Breakdown Rate |
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Abstract |
The scientific community and the medical industries are putting a considerable effort into the design of compact, reliable and cheap accelerators for hadrontherapy. Up to now only circular accelerators are used to deliver beams with energies suitable for the treatment of deep seated tumors. The TERA Foundation has proposed and designed a hadrontherapy facility based on the cyclinac concept: a high gradient linear accelerator placed downstream of a cyclotron used as an injector. The overall length of the linac, and therefore its final cost, is almost inversely proportional to the average accelerating gradient achieved in the linac. TERA, in collaboration with the CLIC RF group, has started a high gradient test program. The main goal is to study the high gradient behavior of prototype cavities and to determine the appropriate linac operating frequency considering important issues such as machine reliability and availability of distributed power sources. A preliminary test of a 3 GHz cavity has been carried out at the beginning of 2010, giving encouraging results. Further investigations are planned before the end of 2011. A set of 5.7 GHz cavities is under production and will be tested in a near future. The construction and test of a multi-cell structure is also foreseen. |
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Address |
[Degiovanni, A; Wegner, R] CERN, CH-1211 Geneva, Switzerland, Email: alberto.degiovanni@cern.ch |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Conference |
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Notes |
WOS:000297085800010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
807 |
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Author |
Garonna, A.; Amaldi, U.; Bonomi, R.; Campo, D.; Degiovanni, A.; Garlasche, M.; Mondino, I.; Rizzoglio, V.; Verdu-Andres, S. |
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Title |
Cyclinac medical accelerators using pulsed C6+/H-2(+) ion sources |
Type |
Journal Article |
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Year |
2010 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
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Volume |
5 |
Issue |
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Pages |
C09004 - 19pp |
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Keywords |
Instrumentation for particle-beam therapy; Instrumentation for hadron therapy; Ion sources (positive ions, negative ions, electron cyclotron resonance (ECR), electron beam (EBIS)); Acceleration cavities and magnets superconducting (high-temperature superconductor; radiation hardened magnets; normal-conducting; permanent magnet devices; wigglers and undulators) |
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Abstract |
Charged particle therapy, or so-called hadrontherapy, is developing very rapidly. There is large pressure on the scientific community to deliver dedicated accelerators, providing the best possible treatment modalities at the lowest cost. In this context, the Italian research Foundation TERA is developing fast-cycling accelerators, dubbed 'cyclinacs'. These are a combination of a cyclotron (accelerating ions to a fixed initial energy) followed by a high gradient linac boosting the ions energy up to the maximum needed for medical therapy. The linac is powered by many independently controlled klystrons to vary the beam energy from one pulse to the next. This accelerator is best suited to treat moving organs with a 4D multipainting spot scanning technique. A dual proton/carbon ion cyclinac is here presented. It consists of an Electron Beam Ion Source, a superconducting isochronous cyclotron and a high-gradient linac. All these machines are pulsed at high repetition rate (100-400 Hz). The source should deliver both C6+ and H-2(+) ions in short pulses (1.5 μs flat-top) and with sufficient intensity (at least 10(8) fully stripped carbon ions per pulse at 300 Hz). The cyclotron accelerates the ions to 120 MeV/u. It features a compact design (with superconducting coils) and a low power consumption. The linac has a novel C-band high-gradient structure and accelerates the ions to variable energies up to 400 MeV/u. High RF frequencies lead to power consumptions which are much lower than the ones of synchrotrons for the same ion extraction energy. This work is part of a collaboration with the CLIC group, which is working at CERN on high-gradient electron-positron colliders. |
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Address |
[Garonna, A.; Amaldi, U.; Bonomi, R.; Campo, D.; Degiovanni, A.; Garlasche, M.; Mondino, I.; Rizzoglio, V.; Andres, S. Verdu] TERA Fdn, I-28100 Novara, Italy, Email: Adriano.Garonna@cern.ch |
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Publisher |
Iop Publishing Ltd |
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English |
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Original Title |
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Series Editor |
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Series Volume |
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Edition |
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ISSN |
1748-0221 |
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Notes |
ISI:000283796100011 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
327 |
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| Permanent link to this record |
