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Author  |
Amaldi, U.; Bonomi, R.; Braccini, S.; Crescenti, M.; Degiovanni, A.; Garlasche, M.; Garonna, A.; Magrin, G.; Mellace, C.; Pearce, P.; Pitta, G.; Puggioni, P.; Rosso, E.; Verdu-Andres, S.; Wegner, R.; Weiss, M.; Zennaro, R. |
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Title |
Accelerators for hadrontherapy: From Lawrence cyclotrons to linacs |
Type |
Journal Article |
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Year |
2010 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
620 |
Issue |
2-3 |
Pages |
563-577 |
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Keywords |
Medical accelerators; Linac; Cyclotron; Synchrotron; Cyclinac; Radiation oncology; Hadrontherapy; Particle therapy; Proton therapy; Carbon ion therapy; Dose delivery |
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Abstract |
Hadrontherapy with protons and carbon ions is a fast developing methodology in radiation oncology. The accelerators used and planned for this purpose are reviewed starting from the cyclotrons used in the thirties. As discussed in the first part of this paper, normal and superconducting cyclotrons are still employed, together with synchrotrons, for proton therapy while for carbon ion therapy synchrotrons have been till now the only option. The latest developments concern a superconducting cyclotron for carbon ion therapy, fast-cycling high frequency linacs and 'single room' proton therapy facilities. These issues are discussed in the second part of the paper by underlining the present challenges, in particular the treatment of moving organs. |
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Address |
[Amaldi, U.; Bonomi, R.; Braccini, S.; Crescenti, M.; Degiovanni, A.; Garlasche, M.; Garonna, A.; Magrin, G.; Mellace, C.; Pearce, P.; Pitta, G.; Puggioni, P.; Rosso, E.; Andres, S. Verdu; Wegner, R.; Weiss, M.; Zennaro, R.] TERA Fdn, Novara, Italy, Email: Saverio.Braccini@cern.ch |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000280601700058 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
401 |
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Author |
Degiovanni, A.; Amaldi, U.; Bonomi, R.; Garlasche, M.; Garonna, A.; Verdu-Andres, S.; Wegner, R. |
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Title |
TERA high gradient test program of RF cavities for medical linear accelerators |
Type |
Journal Article |
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Year |
2011 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
657 |
Issue |
1 |
Pages |
55-58 |
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Keywords |
Medical accelerators; Hadrontherapy; Cyclinac; Linac; RF cavity; Breakdown Rate |
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Abstract |
The scientific community and the medical industries are putting a considerable effort into the design of compact, reliable and cheap accelerators for hadrontherapy. Up to now only circular accelerators are used to deliver beams with energies suitable for the treatment of deep seated tumors. The TERA Foundation has proposed and designed a hadrontherapy facility based on the cyclinac concept: a high gradient linear accelerator placed downstream of a cyclotron used as an injector. The overall length of the linac, and therefore its final cost, is almost inversely proportional to the average accelerating gradient achieved in the linac. TERA, in collaboration with the CLIC RF group, has started a high gradient test program. The main goal is to study the high gradient behavior of prototype cavities and to determine the appropriate linac operating frequency considering important issues such as machine reliability and availability of distributed power sources. A preliminary test of a 3 GHz cavity has been carried out at the beginning of 2010, giving encouraging results. Further investigations are planned before the end of 2011. A set of 5.7 GHz cavities is under production and will be tested in a near future. The construction and test of a multi-cell structure is also foreseen. |
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Address |
[Degiovanni, A; Wegner, R] CERN, CH-1211 Geneva, Switzerland, Email: alberto.degiovanni@cern.ch |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000297085800010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
807 |
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Author |
Degiovanni, A.; Wuensch, W.; Giner Navarro, J. |
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Title |
Comparison of the conditioning of high gradient accelerating structures |
Type |
Journal Article |
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Year |
2016 |
Publication |
Physical Review Accelerators and Beams |
Abbreviated Journal |
Phys. Rev. Accel. Beams |
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Volume |
19 |
Issue |
3 |
Pages |
032001 - 6pp |
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Keywords |
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Abstract |
Accelerating gradients in excess of 100 MV/m, at very low breakdown rates, have been successfully achieved in numerous prototype CLIC accelerating structures. The conditioning and operational histories of several structures, tested at KEK and CERN, have been compared and there is clear evidence that the conditioning progresses with the number of rf pulses and not with the number of breakdowns. This observation opens the possibility that the optimum conditioning strategy, which minimizes the total number of breakdowns the structure is subject to without increasing conditioning time, may be to never exceed the breakdown rate target for operation. The result is also likely to have a strong impact on efforts to understand the physical mechanism underlying conditioning and may lead to preparation procedures which reduce conditioning time. |
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Address |
[Degiovanni, Alberto; Wuensch, Walter] CERN, European Org Nucl Res, CH-1211 Geneva, Switzerland, Email: walter.wuensch@cern.ch |
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Thesis |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
2469-9888 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000400274700001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3090 |
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Author |
Garonna, A.; Amaldi, U.; Bonomi, R.; Campo, D.; Degiovanni, A.; Garlasche, M.; Mondino, I.; Rizzoglio, V.; Verdu-Andres, S. |
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Title |
Cyclinac medical accelerators using pulsed C6+/H-2(+) ion sources |
Type |
Journal Article |
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Year |
2010 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
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Volume |
5 |
Issue |
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Pages |
C09004 - 19pp |
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Keywords |
Instrumentation for particle-beam therapy; Instrumentation for hadron therapy; Ion sources (positive ions, negative ions, electron cyclotron resonance (ECR), electron beam (EBIS)); Acceleration cavities and magnets superconducting (high-temperature superconductor; radiation hardened magnets; normal-conducting; permanent magnet devices; wigglers and undulators) |
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Abstract |
Charged particle therapy, or so-called hadrontherapy, is developing very rapidly. There is large pressure on the scientific community to deliver dedicated accelerators, providing the best possible treatment modalities at the lowest cost. In this context, the Italian research Foundation TERA is developing fast-cycling accelerators, dubbed 'cyclinacs'. These are a combination of a cyclotron (accelerating ions to a fixed initial energy) followed by a high gradient linac boosting the ions energy up to the maximum needed for medical therapy. The linac is powered by many independently controlled klystrons to vary the beam energy from one pulse to the next. This accelerator is best suited to treat moving organs with a 4D multipainting spot scanning technique. A dual proton/carbon ion cyclinac is here presented. It consists of an Electron Beam Ion Source, a superconducting isochronous cyclotron and a high-gradient linac. All these machines are pulsed at high repetition rate (100-400 Hz). The source should deliver both C6+ and H-2(+) ions in short pulses (1.5 μs flat-top) and with sufficient intensity (at least 10(8) fully stripped carbon ions per pulse at 300 Hz). The cyclotron accelerates the ions to 120 MeV/u. It features a compact design (with superconducting coils) and a low power consumption. The linac has a novel C-band high-gradient structure and accelerates the ions to variable energies up to 400 MeV/u. High RF frequencies lead to power consumptions which are much lower than the ones of synchrotrons for the same ion extraction energy. This work is part of a collaboration with the CLIC group, which is working at CERN on high-gradient electron-positron colliders. |
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Address |
[Garonna, A.; Amaldi, U.; Bonomi, R.; Campo, D.; Degiovanni, A.; Garlasche, M.; Mondino, I.; Rizzoglio, V.; Andres, S. Verdu] TERA Fdn, I-28100 Novara, Italy, Email: Adriano.Garonna@cern.ch |
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Corporate Author |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1748-0221 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000283796100011 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
327 |
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Author |
Woolley, B.; Burt, G.; Dexter, A.C.; Peacock, R.; Millar, W.L.; Catalan Lasheras, N.; Degiovanni, A.; Grudiev, A.; Mcmonagle, G.; Syratchev, I.; Wuensch, W.; Rodriguez Castro, E.; Giner Navarro, J. |
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Title |
High-gradient behavior of a dipole-mode rf structure |
Type |
Journal Article |
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Year |
2020 |
Publication |
Physical Review Accelerators and Beams |
Abbreviated Journal |
Phys. Rev. Accel. Beams |
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Volume |
23 |
Issue |
12 |
Pages |
122002 - 11pp |
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Keywords |
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Abstract |
A normal-conducting, X-band traveling wave structure operating in the dipole mode has been systematically high-gradient tested to gain insight into the maximum possible gradients in these types of structure. Measured structure conditioning, breakdown behavior, and achieved surface fields are reported as well as a postmortem analysis of the breakdown position and a scanning electron microscope analysis of the high-field surfaces. The results of these measurements are then compared to high-gradient results from monopole-mode cavities. Scaled to a breakdown rate of 10(-6), the cavities were found to operate at a peak electric field of 154 MV/m and a peak modified Poynting vector S-c of 5.48 MW/mm(2). The study provides important input for the further development of dipole-mode cavities for use in the Compact Linear Collider as a crab cavity and dipole-mode cavities for use in x-ray free-electron lasers as well as for studies of the fundamental processes in vacuum arcs. Of particular relevance are the unique field patterns in dipole cavities compared to monopole cavities, where the electric and magnetic fields peak in orthogonal planes, which allow the separation of the role of electric and magnetic fields in breakdown via postmortem damage observation. The azimuthal variation of breakdown crater density is measured and is fitted to sinusoidal functions. The best fit is a power law fit of exponent 6. This is significant, as it shows how breakdown probability varies over a surface area with a varying electric field after conditioning to a given peak field. |
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Address |
[Woolley, B.; Burt, G.; Dexter, A. C.; Peacock, R.; Millar, W. L.] Univ Lancaster, Lancaster LA1 4YW, England |
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Corporate Author |
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Thesis |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
2469-9888 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000614886300002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4696 |
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| Permanent link to this record |
