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Author Candela-Juan, C.; Niatsetski, Y.; van der Laarse, R.; Granero, D.; Ballester, F.; Perez-Calatayud, J.; Vijande, J. doi  openurl
  Title Design and characterization of a new high-dose-rate brachytherapy Valencia applicator for larger skin lesions Type Journal Article
  Year (down) 2016 Publication Medical Physics Abbreviated Journal Med. Phys.  
  Volume 43 Issue 4 Pages 1639-1648  
  Keywords skin applicator; Valencia applicator; HDR brachytherapy; dosimetry; Monte Carlo  
  Abstract Purpose: The aims of this study were (i) to design a new high-dose-rate (HDR) brachytherapy applicator for treating surface lesions with planning target volumes larger than 3 cm in diameter and up to 5 cm in size, using the microSelectron-HDR or Flexitron afterloader (Elekta Brachytherapy) with a Ir-192 source; (ii) to calculate by means of the Monte Carlo (MC) method the dose distribution for the new applicator when it is placed against a water phantom; and (iii) to validate experimentally the dose distributions in water. Methods: The PENELOPE2008 MC code was used to optimize dwell positions and dwell times. Next, the dose distribution in a water phantom and the leakage dose distribution around the applicator were calculated. Finally, MC data were validated experimentally for a 192Ir mHDR-v2 source by measuring (i) dose distributions with radiochromic EBT3 films (ISP); (ii) percentage depth-dose (PDD) curve with the parallel-plate ionization chamber Advanced Markus (PTW); and (iii) absolute dose rate with EBT3 films and the PinPoint T31016 (PTW) ionization chamber. Results: The new applicator is made of tungsten alloy (Densimet) and consists of a set of interchangeable collimators. Three catheters are used to allocate the source at prefixed dwell positions with preset weights to produce a homogenous dose distribution at the typical prescription depth of 3 mm in water. The same plan is used for all available collimators. PDD, absolute dose rate per unit of air kerma strength, and off-axis profiles in a cylindrical water phantom are reported. These data can be used for treatment planning. Leakage around the applicator was also scored. The dose distributions, PDD, and absolute dose rate calculated agree within experimental uncertainties with the doses measured: differences of MC data with chamber measurements are up to 0.8% and with radiochromic films are up to 3.5%. Conclusions: The new applicator and the dosimetric data provided here will be a valuable tool in clinical practice, making treatment of large skin lesions simpler, faster, and safer. Also the dose to surrounding healthy tissues is minimal.  
  Address [Candela-Juan, C.; Perez-Calatayud, J.] La Fe Univ & Polytech Hosp, Dept Radiat Oncol, Valencia 46026, Spain, Email: ccanjuan@gmail.com  
  Corporate Author Thesis  
  Publisher Amer Assoc Physicists Medicine Amer Inst Physics Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0094-2405 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000373711000007 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2620  
Permanent link to this record
 

 
Author Gimenez-Alventosa, V.; Ballester, F.; Vijande, J. doi  openurl
  Title VoxelMages: a general-purpose graphical interface for designing geometries and processing DICOM images for PENELOPE Type Journal Article
  Year (down) 2016 Publication Applied Radiation And Isotopes Abbreviated Journal Appl. Radiat. Isot.  
  Volume 118 Issue Pages 251-257  
  Keywords 87.53.Bn; 87.53.Jw; 87.55.Qr; 87.55.km; 87.55.K  
  Abstract The design and construction of geometries for Monte Carlo calculations is an error-prone, time-consuming, and complex step in simulations describing particle interactions and transport in the field of medical physics. The software VoxelMages has been developed to help the user in this task. It allows to design complex geometries and to process DICOM image files for simulations with the general-purpose Monte Carlo code PENELOPE in an easy and straightforward way. VoxelMages also allows to import DICOM-RT structure contour information as delivered by a treatment planning system. Its main characteristics, usage and performance benchmarking are described in detail.  
  Address [Gimenez-Alventosa, V.; Ballester, F.; Vijande, J.] Univ Valencia, Dept Fis Atom Mol & Nucl, E-46100 Valencia, Spain  
  Corporate Author Thesis  
  Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0969-8043 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000390736100039 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 2904  
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Author Granero, D.; Candela-Juan, C.; Vijande, J.; Ballester, F.; Perez-Calatayud, J.; Jacob, D.; Mourtada, F. doi  openurl
  Title Technical Note: Dosimetry of Leipzig and Valencia applicators without the plastic cap Type Journal Article
  Year (down) 2016 Publication Medical Physics Abbreviated Journal Med. Phys.  
  Volume 43 Issue 5 Pages 2087 - 4pp  
  Keywords Leipzig applicators; Valencia applicators; skin brachytherapy; Monte Carlo; dosimetry  
  Abstract Purpose: High dose rate (HDR) brachytherapy for treatment of small skin lesions using the Leipzig and Valencia applicators is a widely used technique. These applicators are equipped with an attachable plastic cap to be placed during fraction delivery to ensure electronic equilibrium and to prevent secondary electrons from reaching the skin surface. The purpose of this study is to report on the dosimetric impact of the cap being absent during HDR fraction delivery, which has not been explored previously in the literature. Methods: GEANT4 Monte Carlo simulations (version 10.0) have been performed for the Leipzig and Valencia applicators with and without the plastic cap. In order to validate the Monte Carlo simulations, experimental measurements using radiochromic films have been done. Results: Dose absorbed within 1 mm of the skin surface increases by a factor of 1500% for the Leipzig applicators and of 180% for the Valencia applicators. Deeper than 1 mm, the overdosage flattens up to a 10% increase. Conclusions: Differences of treating with or without the plastic cap are significant. Users must check always that the plastic cap is in place before any treatment in order to avoid overdosage of the skin. Prior to skin HDR fraction delivery, the timeout checklist should include verification of the cap placement. (C) 2016 American Association of Physicists in Medicine.  
  Address [Granero, D.] Hosp Gen Univ, Dept Radiat Phys, ERESA, Valencia 46014, Spain, Email: dgranero@eresa.com  
  Corporate Author Thesis  
  Publisher Amer Assoc Physicists Medicine Amer Inst Physics Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0094-2405 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000378924200010 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2753  
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Author Vijande, J.; Valcarce, A.; Richard, J.M.; Sorba, P. url  doi
openurl 
  Title Search for doubly-heavy dibaryons in a quark model Type Journal Article
  Year (down) 2016 Publication Physical Review D Abbreviated Journal Phys. Rev. D  
  Volume 94 Issue 3 Pages 034038 - 6pp  
  Keywords  
  Abstract We study the stability of hexaquark systems containing two heavy quarks and four light quarks within a simple quark model. No bound or metastable state is found. The reason stems from a delicate interplay between chromoelectric and chromomagnetic effects. Our calculation also provides information about anticharmed pentaquarks that are seemingly unbound in simple quark models.  
  Address [Vijande, J.] UV, Dept Fis Atom Mol & Nucl, E-46100 Valencia, Spain, Email: javier.vijande@uv.es;  
  Corporate Author Thesis  
  Publisher Amer Physical Soc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2470-0010 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000381893500004 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2778  
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Author Carames, T.F.; Fontoura, C.E.; Krein, G.; Tsushima, K.; Vijande, J.; Valcarce, A. url  doi
openurl 
  Title Hadronic molecules with a (D)over-bar meson in a medium Type Journal Article
  Year (down) 2016 Publication Physical Review D Abbreviated Journal Phys. Rev. D  
  Volume 94 Issue 3 Pages 034009 - 10pp  
  Keywords  
  Abstract We study the effect of a hot and dense medium on the binding energy of hadronic molecules with open-charm mesons. We focus on a recent chiral quark-model-based prediction of a molecular state in the N (D) over bar system. We analyze how the two-body thresholds and the hadron-hadron interactions are modified when quark and meson masses and quark-meson couplings change in a function of the temperature and baryon density according to predictions of the Nambu-Jona-Lasinio model. We find that in some cases the molecular binding is enhanced in medium as compared to their free-space binding. We discuss the consequences of our findings for the search for exotic hadrons in high-energy heavy-ion collisions as well as in the forthcoming facilities FAIR or J-PARC.  
  Address [Carames, T. F.; Valcarce, A.] Univ Salamanca, Dept Fis Fundamental, E-37008 Salamanca, Spain, Email: carames@usal.es;  
  Corporate Author Thesis  
  Publisher Amer Physical Soc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2470-0010 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000380961500002 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 2780  
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