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Weber, M. et al, & Esperante, D. (2024). DONES EVO: Risk mitigation for the IFMIF-DONES facility. Nucl. Mater. Energy, 38, 101622–5pp.
Abstract: The International Fusion Materials Irradiation Facility- DEMO Oriented Neutron Source (IFMIF-DONES) is a scientific infrastructure aimed to provide an intense neutron source for the qualification of materials to be used in future fusion power reactors. Its implementation is critical for the construction of the fusion DEMOnstration Power Plant (DEMO). IFMIF-DONES is a unique facility requiring a broad set of technologies. Although most of the necessary technologies have already been validated, there are still some aspects that introduce risks in the evolution of the project. In order to mitigate these risks, a consortium of companies, with the support of research centres and the funding of the CDTI (Centre for the Development of Industrial Technology and Innovation), has launched the DONES EVO Programme, which comprises six lines of research: center dot Improvement of signal transmission and integrity (planning and integration risks) center dot Optimisation of RF conditioning processes (planning and reliability risks) center dot Development of a reliable beam extraction device (reliability risks) center dot Development of technologies for the production of medical isotopes (reliability risks) center dot Improvement of critical parts of the lithium purification system (safety and reliability risks) center dot Validation of the manufacture of critical components with special materials (reliability risk). DONES EVO will focus on developing the appropriate response to the risks identified in the IFMIFDONES project through research and prototyping around the associated technologies.
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Di Bari, P., King, S. F., & Hossain Rahat, M. (2024). Gravitational waves from phase transitions and cosmic strings in neutrino mass models with multiple majorons. J. High Energy Phys., 05(5), 068–31pp.
Abstract: We explore the origin of Majorana masses within the majoron model and how this can lead to the generation of a distinguishable primordial stochastic background of gravitational waves. We first show how in the simplest majoron model only a contribution from cosmic string can be within the reach of planned experiments. We then consider extensions containing multiple complex scalars, demonstrating how in this case a spectrum comprising contributions from both a strong first order phase transition and cosmic strings can naturally emerge. We show that the interplay between multiple scalar fields can amplify the phase transition signal, potentially leading to double peaks over the wideband sloped spectrum from cosmic strings. We also underscore the possibility of observing such a gravitational wave background to provide insights into the reheating temperature of the universe. We conclude highlighting how the model can be naturally combined with scenarios addressing the origin of matter of the universe, where baryogenesis occurs via leptogenesis and a right-handed neutrino plays the role of dark matter.
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Di Gregorio, E., Staelens, M., Hosseinkhah, N., Karimpoor, M., Liburd, J., Lim, L., et al. (2024). Raman Spectroscopy Reveals Photobiomodulation-Induced α-Helix to β-Sheet Transition in Tubulins: Potential Implications for Alzheimer's and Other Neurodegenerative Diseases. Nanomaterials, 14(13), 1093–21pp.
Abstract: In small clinical studies, the application of transcranial photobiomodulation (PBM), which typically delivers low-intensity near-infrared (NIR) to treat the brain, has led to some remarkable results in the treatment of dementia and several neurodegenerative diseases. However, despite the extensive literature detailing the mechanisms of action underlying PBM outcomes, the specific mechanisms affecting neurodegenerative diseases are not entirely clear. While large clinical trials are warranted to validate these findings, evidence of the mechanisms can explain and thus provide credible support for PBM as a potential treatment for these diseases. Tubulin and its polymerized state of microtubules have been known to play important roles in the pathology of Alzheimer's and other neurodegenerative diseases. Thus, we investigated the effects of PBM on these cellular structures in the quest for insights into the underlying therapeutic mechanisms. In this study, we employed a Raman spectroscopic analysis of the amide I band of polymerized samples of tubulin exposed to pulsed low-intensity NIR radiation (810 nm, 10 Hz, 22.5 J/cm2 dose). Peaks in the Raman fingerprint region (300-1900 cm-1)-in particular, in the amide I band (1600-1700 cm-1)-were used to quantify the percentage of protein secondary structures. Under this band, hidden signals of C=O stretching, belonging to different structures, are superimposed, producing a complex signal as a result. An accurate decomposition of the amide I band is therefore required for the reliable analysis of the conformation of proteins, which we achieved through a straightforward method employing a Voigt profile. This approach was validated through secondary structure analyses of unexposed control samples, for which comparisons with other values available in the literature could be conducted. Subsequently, using this validated method, we present novel findings of statistically significant alterations in the secondary structures of polymerized NIR-exposed tubulin, characterized by a notable decrease in alpha-helix content and a concurrent increase in beta-sheets compared to the control samples. This PBM-induced alpha-helix to beta-sheet transition connects to reduced microtubule stability and the introduction of dynamism to allow for the remodeling and, consequently, refreshing of microtubule structures. This newly discovered mechanism could have implications for reducing the risks associated with brain aging, including neurodegenerative diseases like Alzheimer's disease, through the introduction of an intervention following this transition.
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CALICE Collaboration(Lai, S. et al), & Irles, A. (2024). Software compensation for highly granular calorimeters using machine learning. J. Instrum., 19(4), P04037–28pp.
Abstract: A neural network for software compensation was developed for the highly granular CALICE Analogue Hadronic Calorimeter (AHCAL). The neural network uses spatial and temporal event information from the AHCAL and energy information, which is expected to improve sensitivity to shower development and the neutron fraction of the hadron shower. The neural network method produced a depth-dependent energy weighting and a time-dependent threshold for enhancing energy deposits consistent with the timescale of evaporation neutrons. Additionally, it was observed to learn an energy-weighting indicative of longitudinal leakage correction. In addition, the method produced a linear detector response and outperformed a published control method regarding resolution for every particle energy studied.
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Bhattacharya, S., Mondal, N., Roshan, R., & Vatsyayan, D. (2024). Leptogenesis, dark matter and gravitational waves from discrete symmetry breaking. J. Cosmol. Astropart. Phys., 06(6), 029–25pp.
Abstract: We analyse a model that connects the neutrino sector and the dark sector of the universe via a mediator 41., stabilised by a discrete Z4 symmetry that breaks to a remnant Z2 upon 41. acquiring a non -zero vacuum expectation value (v phi). The model accounts for the observed baryon asymmetry of the universe via additional contributions to the canonical Type -I leptogenesis. The Z4 symmetry breaking scale (v phi) in the model not only establishes a connection between the neutrino sector and the dark sector, but could also lead to gravitational wave signals that are within the reach of current and future experimental sensitivities.
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Lessa, L. A., Maluf, R. V., Silva, J. E. G., & Almeida, C. A. S. (2024). Braneworlds in warped Einsteinian cubic gravity. J. Cosmol. Astropart. Phys., 05(5), 123–25pp.
Abstract: Einstenian cubic gravity (ECG) is a modified theory of gravity constructed with cubic contractions of the curvature tensor. This theory has the remarkable feature of having the same two propagating degrees of freedom of Einstein gravity (EG), at the perturbative level on maximally symmetric spacetimes. The additional unstable modes steaming from the higher order derivative dynamics are suppressed provided that we consider the ECG as an effective field theory wherein the cubic terms are seen as perturbative corrections of the Einstein -Hilbert term. Extensions of ECG have been proposed in cosmology and compact objects in order to probe if this property holds in more general configurations. In this work, we construct a modified ECG gravity in a five dimensional warped braneworld scenario. By assuming a specific combination of the cubic parameters, we obtained modified gravity equations of motion with terms up to second -order. For a thin 3-brane, the cubic -gravity corrections yield an effective positive bulk cosmological constant. Thus, in order to keep the 5D bulk warped compact, an upper bound of the cubic parameter with respect to the bulk curvature was imposed. For a thick brane, the cubic -gravity terms modify the scalar field potential and its corresponding vacuum. Nonetheless, the domain -wall structure with a localized source is preserved. At the perturbative level, the Kaluza-Klein (KK) tensor gravitational modes are stable and possess a localized massless mode provided the cubic corrections are small compared to the EG braneworld.
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Fernandez Navarro, M., King, S. F., & Vicente, A. (2024). Tri-unification: a separate SU(5) for each fermion family. J. High Energy Phys., 05(5), 130–32pp.
Abstract: In this paper we discuss SU(5)3 with cyclic symmetry as a possible grand unified theory (GUT). The basic idea of such a tri-unification is that there is a separate SU(5) for each fermion family, with the light Higgs doublet(s) arising from the third family SU(5), providing a basis for charged fermion mass hierarchies. SU(5)3 tri-unification reconciles the idea of gauge non-universality with the idea of gauge coupling unification, opening the possibility to build consistent non-universal descriptions of Nature that are valid all the way up to the scale of grand unification. As a concrete example, we propose a grand unified embedding of the tri-hypercharge model \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\text{U}}{\left(1\right)}_{Y}<^>{3}$$\end{document} based on an SU(5)3 framework with cyclic symmetry. We discuss a minimal tri-hypercharge example which can account for all the quark and lepton (including neutrino) masses and mixing parameters. We show that it is possible to unify the many gauge couplings into a single gauge coupling associated with the cyclic SU(5)3 gauge group, by assuming minimal multiplet splitting, together with a set of relatively light colour octet scalars. We also study proton decay in this example, and present the predictions for the proton lifetime in the dominant e+pi 0 channel.
Keywords: Grand Unification; Theories of Flavour
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Belchior, F. M., & Maluf, R. (2024). Duality between the Maxwell-Chern-Simons and self-dual models in very special relativity. Phys. Lett. B, 855, 138794–7pp.
Abstract: This work investigates the classical and quantum duality between the SIM (1)-Maxwell-Chern-Simons (MCS) model and its self -dual counterpart. Initially, we focus on free -field cases to establish equivalence through two distinct approaches: comparing the equations of motion and utilizing the master Lagrangian method. In both instances, the classical correspondence between the self -dual and MCS dual fields undergoes modifications due to very special relativity (VSR). Specifically, the duality is established when the associated VSR-mass parameters are identical, and the dual field is introduced through a non -local VSR correction. Furthermore, we analyze the duality when the self -dual model is minimally coupled to fermions. As a result, we demonstrate that Thirring-like interactions, corrected for non -local VSR contributions, are included in the MCS model. Additionally, we establish the quantum equivalence of the models by performing a functional integration of the fields and comparing the resulting effective Lagrangians.
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Forconi, M., Giare, W., Mena, O., Ruchika, Di Valentino, E., Melchiorri, A., et al. (2024). A double take on early and interacting dark energy from JWST. J. Cosmol. Astropart. Phys., 05(5), 097–37pp.
Abstract: The very first light captured by the James Webb Space Telescope (JWST) revealed a population of galaxies at very high redshifts more massive than expected in the canonical Lambda CDM model of structure formation. Barring, among others, a systematic origin of the issue, in this paper, we test alternative cosmological perturbation histories. We argue that models with a larger matter component ohm m and/or a larger scalar spectral index n s can substantially improve the fit to JWST measurements. In this regard, phenomenological extensions related to the dark energy sector of the theory are appealing alternatives, with Early Dark Energy emerging as an excellent candidate to explain (at least in part) the unexpected JWST preference for larger stellar mass densities. Conversely, Interacting Dark Energy models, despite producing higher values of matter clustering parameters such as sigma 8 , are generally disfavored by JWST measurements. This is due to the energy -momentum flow from the dark matter to the dark energy sector, implying a smaller matter energy density. Upcoming observations may either strengthen the evidence or falsify some of these appealing phenomenological alternatives to the simplest Lambda CDM picture.
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Agius, D., Essig, R., Gaggero, D., Scarcella, F., Suczewski, G., & Valli, M. (2024). Feedback in the dark: a critical examination of CMB bounds on primordial black holes. J. Cosmol. Astropart. Phys., 07(7), 003–36pp.
Abstract: If present in the early universe, primordial black holes (PBHs) would have accreted matter and emitted high-energy photons, altering the statistical properties of the Cosmic Microwave Background (CMB). This mechanism has been used to constrain the fraction of dark matter that is in the form of PBHs to be much smaller than unity for PBH masses well above one solar mass. Moreover, the presence of dense dark matter mini -halos around the PBHs has been used to set even more stringent constraints, as these would boost the accretion rates. In this work, we critically revisit CMB constraints on PBHs taking into account the role of the local ionization of the gas around them. We discuss how the local increase in temperature around PBHs can prevent the dark matter mini -halos from strongly enhancing the accretion process, in some cases significantly weakening previously derived CMB constraints. We explore in detail the key ingredients of the CMB bound and derive a conservative limit on the cosmological abundance of massive PBHs.
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