| Home | [1–10] << 11 12 13 14 15 16 17 18 19 20 >> [21–30] |
|
Valdes-Cortez, C., Niatsetski, Y., Perez-Calatayud, J., Ballester, F., & Vijande, J. (2022). A Monte Carlo study of the relative biological effectiveness in surface brachytherapy. Med. Phys., 49, 5576–5588.
Abstract: Purpose This work aims to simulate clustered DNA damage from ionizing radiation and estimate the relative biological effectiveness (RBE) for radionuclide (rBT)- and electronic (eBT)-based surface brachytherapy through a hybrid Monte Carlo (MC) approach, using realistic models of the sources and applicators. Methods Damage from ionizing radiation has been studied using the Monte Carlo Damage Simulation algorithm using as input the primary electron fluence simulated using a state-of-the-art MC code, PENELOPE-2018. Two Ir-192 rBT applicators, Valencia and Leipzig, one Co-60 source with a Freiburg Flap applicator (reference source), and two eBT systems, Esteya and INTRABEAM, have been included in this study implementing full realizations of their geometries as disclosed by the manufacturer. The role played by filtration and tube kilovoltage has also been addressed. Results For rBT, an RBE value of about 1.01 has been found for the applicators and phantoms considered. In the case of eBT, RBE values for the Esteya system show an almost constant RBE value of about 1.06 for all depths and materials. For INTRABEAM, variations in the range of 1.12-1.06 are reported depending on phantom composition and depth. Modifications in the Esteya system, filtration, and tube kilovoltage give rise to variations in the same range. Conclusions Current clinical practice does not incorporate biological effects in surface brachytherapy. Therefore, the same absorbed dose is administered to the patients independently on the particularities of the rBT or eBT system considered. The almost constant RBE values reported for rBT support that assumption regardless of the details of the patient geometry, the presence of a flattening filter in the applicator design, or even significant modifications in the photon energy spectra above 300 keV. That is not the case for eBT, where a clear dependence on the eBT system and the characteristics of the patient geometry are reported. A complete study specific for each eBT system, including detailed applicator characteristics (size, shape, filtering, among others) and common anatomical locations, should be performed before adopting an existing RBE value.
|
|
Stoppa, F., Vreeswijk, P., Bloemen, S., Bhattacharyya, S., Caron, S., Johannesson, G., et al. (2022). AutoSourceID-Light Fast optical source localization via U-Net and Laplacian of Gaussian. Astron. Astrophys., 662, A109–8pp.
Abstract: Aims. With the ever-increasing survey speed of optical wide-field telescopes and the importance of discovering transients when they are still young, rapid and reliable source localization is paramount. We present AutoSourceID-Light (ASID-L), an innovative framework that uses computer vision techniques that can naturally deal with large amounts of data and rapidly localize sources in optical images. Methods. We show that the ASID-L algorithm based on U-shaped networks and enhanced with a Laplacian of Gaussian filter provides outstanding performance in the localization of sources. A U-Net network discerns the sources in the images from many different artifacts and passes the result to a Laplacian of Gaussian filter that then estimates the exact location. Results. Using ASID-L on the optical images of the MeerLICHT telescope demonstrates the great speed and localization power of the method. We compare the results with SExtractor and show that our method outperforms this more widely used method. ASID-L rapidly detects more sources not only in low- and mid-density fields, but particularly in areas with more than 150 sources per square arcminute. The training set and code used in this paper are publicly available.
Keywords: astronomical databases; miscellaneous; methods; data analysis; stars; imaging; techniques; image processing
|
|
Roser, J., Barrientos, L., Bernabeu, J., Borja-Lloret, M., Muñoz, E., Ros, A., et al. (2022). Joint image reconstruction algorithm in Compton cameras. Phys. Med. Biol., 67(15), 155009–15pp.
Abstract: Objective. To demonstrate the benefits of using an joint image reconstruction algorithm based on the List Mode Maximum Likelihood Expectation Maximization that combines events measured in different channels of information of a Compton camera. Approach. Both simulations and experimental data are employed to show the algorithm performance. Main results. The obtained joint images present improved image quality and yield better estimates of displacements of high-energy gamma-ray emitting sources. The algorithm also provides images that are more stable than any individual channel against the noisy convergence that characterizes Maximum Likelihood based algorithms. Significance. The joint reconstruction algorithm can improve the quality and robustness of Compton camera images. It also has high versatility, as it can be easily adapted to any Compton camera geometry. It is thus expected to represent an important step in the optimization of Compton camera imaging.
|
|
Pich, A., & Rodriguez-Sanchez, A. (2022). Violations of quark-hadron duality in low-energy determinations of alpha(s). J. High Energy Phys., 07(7), 145–42pp.
Abstract: Using the spectral functions measured in tau decays, we investigate the actual numerical impact of duality violations on the extraction of the strong coupling. These effects are tiny in the standard alpha(s)(m(tau)(2)) determinations from integrated distributions of the hadronic spectrum with pinched weights, or from the total tau hadronic width. The pinched-weight factors suppress very efficiently the violations of duality, making their numerical effects negligible in comparison with the larger perturbative uncertainties. However, combined fits of alpha(s) and duality-violation parameters, performed with non-protected weights, are subject to large systematic errors associated with the assumed modelling of duality-violation effects. These uncertainties have not been taken into account in the published analyses, based on specific models of quark-hadron duality.
|
|
Delhom, A., Mariz, T., Nascimento, J. R., Olmo, G. J., Petrov, A. Y., & Porfirio, P. J. (2022). Spontaneous Lorentz symmetry breaking and one-loop effective action in the metric-affine bumblebee gravity. J. Cosmol. Astropart. Phys., 07(7), 018–27pp.
Abstract: The metric-affine bumblebee model in the presence of fermionic matter minimally coupled to the connection is studied. We show that the model admits an Einstein frame representation in which the matter sector is described by a non-minimal Dirac action without any analogy in the literature. Such non-minimal terms involve unconventional couplings between the bumblebee and the fermion field. We then rewrite the quadratic fermion action in the Einstein frame in the basis of 16 Dirac matrices in order to identify the coefficients for Lorentz/CPT violation in all orders of the non-minimal coupling xi. The exact result for the fermionic determinant in the Einstein frame, including all orders in xi, is also provided. We demonstrate that the axial contributions are at least of second order in the perturbative expansion of xi. Furthermore, we compute the one-loop effective potential within the weak field approximation.
|
|
LHCb Collaboration(Aaij, R. et al), Jashal, B. K., Martinez-Vidal, F., Oyanguren, A., Remon Alepuz, C., & Ruiz Vidal, J. (2022). Centrality determination in heavy-ion collisions with the LHCb detector. J. Instrum., 17(5), P05009–31pp.
Abstract: The centrality of heavy-ion collisions is directly related to the created medium in these interactions. A procedure to determine the centrality of collisions with the LHCb detector is implemented for lead-lead collisions root s(NN) = 5 TeV and lead-neon fixed-target collisions at root s(NN) = 69 GeV. The energy deposits in the electromagnetic calorimeter are used to determine and define the centrality classes. The correspondence between the number of participants and the centrality for the lead-lead collisions is in good agreement with the correspondence found in other experiments, and the centrality measurements for the lead-neon collisions presented here are performed for the first time in fixed-target collisions at the LHC.
|
|
Vitez-Sveiczer, A. et al, Algora, A., Morales, A. I., Rubio, B., Agramunt, J., Guadilla, V., et al. (2022). The beta-decay of Kr-70 into Br-70: Restoration of the pseudo-SU(4) symmetry. Phys. Lett. B, 830, 137123–8pp.
Abstract: The beta-decay of the even-even nucleus Kr-70 with Z=N+2, has been investigated at the Radioactive Ion Beam Factory (RIBF) of the RIKEN Nishina Center using the BigRIPS fragment separator, the ZeroDegree Spectrometer, the WAS3ABI implantation station and the EURICA HPGe cluster array. Fifteen gamma-rays associated with the beta-decay of( 70)Kr into Br-70 have been identified for the first time, defining ten populated states below E-exc=3300 keV. The half-life of Kr-70 was derived with increased precision and found to be t(1/2)=45.19 +/- 0.14 ms. The beta-delayed proton emission probability has also been determined as epsilon(p)=0.545(23)%. An increase in the beta-strength to the yrast 1(+) state in comparison with the heaviest Z=N+2 system studied so far (Ge-62 decay) is observed that may indicate increased np correlations in the T=0 channel. The beta-decay strength deduced from the results is interpreted in terms of the proton-neutron quasiparticle random-phase approximation (pnQRPA) and also with a schematic model that includes isoscalar and isovector pairing in addition to quadrupole deformation. The application of this last model indicates an approximate realization of pseudo-SU(4) symmetry in this system.
|
|
Arbelaez, C., Cepedello, R., Helo, J. C., Hirsch, M., & Kovalenko, S. (2022). How many 1-loop neutrino mass models are there? J. High Energy Phys., 08(8), 023–29pp.
Abstract: It is well-known that at tree-level the d = 5 Weinberg operator can be generated in exactly three different ways, the famous seesaw models. In this paper we study the related question of how many phenomenologically consistent 1-loop models one can construct at d=5. First, we discuss that there are two possible classes of 1-loop neutrino mass models, that allow avoiding stable charged relics: (i) models with dark matter candidates and (ii) models with “exits”. Here, we define “exits” as particles that can decay into standard model fields. Considering 1-loop models with new scalars and fermions, we find in the dark matter class a total of (115+203) models, while in the exit class we find (38+368) models. Here, 115 is the number of DM models, which require a stabilizing symmetry, while 203 is the number of models which contain a dark matter candidate, which maybe accidentally stable. In the exit class the 38 refers to models, for which one (or two) of the internal particles in the loop is a SM field, while the 368 models contain only fields beyond the SM (BSM) in the neutrino mass diagram. We then study the RGE evolution of the gauge couplings in all our 1-loop models. Many of the models in our list lead to Landau poles in some gauge coupling at rather low energies and there is exactly one model which unifies the gauge couplings at energies above 10(15) GeV in a numerically acceptable way.
|
|
Assam, I., Vijande, J., Ballester, F., Perez-Calatayud, J., Poppe, B., & Siebert, F. A. (2022). Evaluation of dosimetric effects of metallic artifact reduction and tissue assignment on Monte Carlo dose calculations for I-125 prostate implants. Med. Phys., 49, 6195–6208.
Abstract: Purpose Monte Carlo (MC) simulation studies, aimed at evaluating the magnitude of tissue heterogeneity in I-125 prostate permanent seed implant brachytherapy (BT), customarily use clinical post-implant CT images to generate a virtual representation of a realistic patient model (virtual patient model). Metallic artifact reduction (MAR) techniques and tissue assignment schemes (TAS) are implemented on the post-implant CT images to mollify metallic artifacts due to BT seeds and to assign tissue types to the voxels corresponding to the bright seed spots and streaking artifacts, respectively. The objective of this study is to assess the combined influence of MAR and TAS on MC absorbed dose calculations in post-implant CT-based phantoms. The virtual patient models used for I-125 prostate implant MC absorbed dose calculations in this study are derived from the CT images of an external radiotherapy prostate patient without BT seeds and prostatic calcifications, thus averting the need to implement MAR and TAS. Methods The geometry of the IsoSeed I25.S17plus source is validated by comparing the MC calculated results of the TG-43 parameters for the line source approximation with the TG-43U1S2 consensus data. Four MC absorbed dose calculations are performed in two virtual patient models using the egs_brachy MC code: (1) TG-43-based D-w,w-TG(43), (2) D-w,D-w-MBDC that accounts for interseed scattering and attenuation (ISA), (3) D-m,D-m that examines ISA and tissue heterogeneity by scoring absorbed dose in tissue, and (4) D-w,D-m that unlike D-m,D-m scores absorbed dose in water. The MC absorbed doses (1) and (2) are simulated in a TG-43 patient phantom derived by assigning the densities of every voxel to 1.00 g cm(-3) (water), whereas MC absorbed doses (3) and (4) are scored in the TG-186 patient phantom generated by mapping the mass density of each voxel to tissue according to a CT calibration curve. The MC absorbed doses calculated in this study are compared with VariSeed v8.0 calculated absorbed doses. To evaluate the dosimetric effect of MAR and TAS, the MC absorbed doses of this work (independent of MAR and TAS) are compared to the MC absorbed doses of different I-125 source models from previous studies that were calculated with different MC codes using post-implant CT-based phantoms generated by implementing MAR and TAS on post-implant CT images. Results The very good agreement of TG-43 parameters of this study and the published consensus data within 3% validates the geometry of the IsoSeed I25.S17plus source. For the clinical studies, the TG-43-based calculations show a D-90 overestimation of more than 4% compared to the more realistic MC methods due to ISA and tissue composition. The results of this work generally show few discrepancies with the post-implant CT-based dosimetry studies with respect to the D-90 absorbed dose metric parameter. These discrepancies are mainly Type B uncertainties due to the different I-125 source models and MC codes. Conclusions The implementation of MAR and TAS on post-implant CT images have no dosimetric effect on the I-125 prostate MC absorbed dose calculation in post-implant CT-based phantoms.
|
|
Bernigaud, J., Blanke, M., de Medeiros Varzielas, I., Talbert, J., & Zurita, J. (2022). LHC signatures of tau-flavoured vector leptoquarks. J. High Energy Phys., 08(8), 127–31pp.
Abstract: We consider the phenomenological signatures of Simplified Models of Flavourful Leptoquarks, whose Beyond-the-Standard Model (SM) couplings to fermion generations occur via textures that are well motivated from a broad class of ultraviolet flavour models (which we briefly review). We place particular emphasis on the study of the vector leptoquark Delta(mu) with assignments (3, 1, 2/3) under the SM's gauge symmetry, SU(3)(C) x SU(2)(L) x U(1)(Y), which has the tantalising possibility of explaining both R-K(*) and R-D(*) anomalies. Upon performing global likelihood scans of the leptoquark's coupling parameter space, focusing in particular on models with tree-level couplings to a single charged lepton species, we then provide confidence intervals and benchmark points preferred by low(er)-energy flavour data. Finally, we use these constraints to further evaluate the (promising) Large Hadron Collider (LHC) detection prospects of pairs of tau-flavoured Delta(mu), through their distinct (a)symmetric decay channels. Namely, we consider direct third-generation leptoquark and jets plus missing-energy searches at the LHC, which we find to be complementary. Depending on the simplified model under consideration, the direct searches constrain the Delta(mu), mass up to 1500-1770 GeV when the branching fraction of Delta(mu), is entirely to third-generation quarks (but are significantly reduced with decreased branching ratios to the third generation), whereas the missing-energy searches constrain the mass up to 1150-1700 GeV while being largely insensitive to the third-generation branching fraction.
|