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Author |
Briz, J.A.; Nerio, A.N.; Ballesteros, C.; Borge, M.J.G.; Martinez, P.; Perea, A.; Tavora, V.G.; Tengblad, O.; Ciemala, M.; Maj, A.; Olko, P.; Parol, W.; Pedracka, A.; Sowicki, B.; Zieblinski, M.; Nacher, E. |
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Title |
Proton Radiographs Using Position-Sensitive Silicon Detectors and High-Resolution Scintillators |
Type |
Journal Article |
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Year  |
2022 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
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Volume |
69 |
Issue |
4 |
Pages |
696-702 |
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Keywords |
LaBr3; particle tracking; proton computed tomography (pCT); proton radiograph; proton therapy; scintillation detectors; silicon detectors |
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Abstract |
Proton therapy is a cancer treatment technique currently in growth since it offers advantages with respect to conventional X-ray and gamma-ray radiotherapy. In particular, better control of the dose deposition allowing to reach higher conformity in the treatments causing less secondary effects. However, in order to take full advantage of its potential, improvements in treatment planning and dose verification are required. A new prototype of proton computed tomography scanner is proposed to design more accurate and precise treatment plans for proton therapy. Our prototype is formed by double-sided silicon strip detectors and scintillators of LaBr3(Ce) with high energy resolution and fast response. Here, the results obtained from an experiment performed using a 100-MeV proton beam are presented. Proton radiographs of polymethyl methacrylate (PMMA) samples of 50-mm thickness with spatial patterns in aluminum were taken. Their properties were studied, including reproduction of the dimensions, spatial resolution, and sensitivity to different materials. Structures of up to 2 mm are well resolved and the sensitivity of the system was enough to distinguish the thicknesses of 10 mm of aluminum or PMMA. The spatial resolution of the images was 0.3 line pairs per mm (MTF-10%). This constitutes the first step to validate the device as a proton radiography scanner. |
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Address |
[Briz, J. A.; Nerio, A. N.; Ballesteros, C.; Borge, M. J. G.; Martinez, P.; Perea, A.; Tavora, V. G.; Tengblad, O.] Inst Estruct Mat CSIC, Madrid 28006, Spain, Email: jose.briz@csic.es |
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Ieee-Inst Electrical Electronics Engineers Inc |
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English |
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ISSN |
0018-9499 |
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Conference |
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Notes |
WOS:000803113800017 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5245 |
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Author |
LHCb Collaboration (Aaij, R. et al); Jashal, B.K.; Martinez-Vidal, F.; Oyanguren, A.; Remon Alepuz, C.; Ruiz Vidal, J. |
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Title |
Precision measurement of forward Z boson production in proton-proton collisions at root s=13 TeV |
Type |
Journal Article |
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Year |
2022 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
07 |
Issue |
7 |
Pages |
026 - 57pp |
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Keywords |
Electroweak Interaction; Forward Physics; Hadron-Hadron Scattering; Particle and Resonance Production |
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Abstract |
A precision measurement of the Z boson production cross-section at root s = 13 TeV in the forward region is presented, using pp collision data collected by the LHCb detector, corresponding to an integrated luminosity of 5.1 fb(-1). The production cross-section is measured using Z -> mu(+)mu(-) events within the fiducial region defined as pseudorapidity 2.0 < eta < 4.5 and transverse momentum p(T) > 20 GeV/c for both muons and dimuon invariant mass 60 < M-mu μ< 120 GeV/c(2). The integrated cross-section is determined to be sigma(Z -> mu(+)mu(-)) = 196.4 +/- 0.2 +/- 1.6 +/- 3.9 pb, where the first uncertainty is statistical, the second is systematic, and the third is due to the luminosity determination. The measured results are in agreement with theoretical predictions within uncertainties. |
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Address |
[de Souza Leite, J. Baptista; Bediaga, I; Torres, M. Cruz; De Miranda, J. M.; dos Reis, A. C.; Falcao, L. N.; Gomes, A.; Massafferri, A.; Machado, D. Torres] Ctr Brasileiro Pesquisas Fis CBPF, Rio De Janeiro, Brazil, Email: hang.yin@cern.ch |
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Springer |
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English |
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Abbreviated Series Title |
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ISSN |
1029-8479 |
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Conference |
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Notes |
WOS:000825333400003 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5299 |
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Author |
LHCb Collaboration (Aaij, R. et al); Henry, L.; Jashal, B.K.; Martinez-Vidal, F.; Oyanguren, A.; Remon Alepuz, C.; Ruiz Vidal, J. |
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Title |
Study of coherent J/psi production in lead-lead collisions at root S-NN=5 TeV |
Type |
Journal Article |
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Year |
2022 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
07 |
Issue |
7 |
Pages |
117 - 19pp |
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Keywords |
Heavy Ion Experiments; Particle and Resonance Production; QCD; Quarkonium; Relativistic Heavy Ion Physics |
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Abstract |
Coherent production of J/psi mesons is studied in ultraperipheral lead-lead collisions at a nucleon-nucleon centre-of-mass energy of 5 TeV, using a data sample collected by the LHCb experiment corresponding to an integrated luminosity of about 10 μb(-1). The J/psi mesons are reconstructed in the dimuon final state and are required to have transverse momentum below 1 GeV. The cross-section within the rapidity range of 2.0 < y < 4.5 is measured to be 4.45 +/- 0.24 +/- 0.18 +/- 0.58 mb, where the first uncertainty is statistical, the second systematic and the third originates from the luminosity determination. The cross-section is also measured in J/psi rapidity intervals. The results are compared to predictions from phenomenological models. |
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Address |
[Leite, J. Baptista; Bediaga, I; Torres, M. Cruz; De Miranda, J. M.; dos Reis, A. C.; Gomes, A.; Massafferri, A.; Machado, D. Torres] Ctr Brasileiro Pesquisas Fis CBPF, Rio De Janeiro, Brazil, Email: albert.frithjof.bursche@cern.ch |
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Corporate Author |
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Publisher |
Springer |
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Language |
English |
Summary Language |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1029-8479 |
ISBN |
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Conference |
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Notes |
WOS:000829159300002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5309 |
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Author |
Assam, I.; Vijande, J.; Ballester, F.; Perez-Calatayud, J.; Poppe, B.; Siebert, F.A. |
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Title |
Evaluation of dosimetric effects of metallic artifact reduction and tissue assignment on Monte Carlo dose calculations for I-125 prostate implants |
Type |
Journal Article |
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Year |
2022 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
49 |
Issue |
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Pages |
6195-6208 |
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Keywords |
metallic artifact reduction; Monte Carlo dosimetry; post-implant CT; prostate brachytherapy; tissue assignment schemes; voxelized virtual patient model |
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Abstract |
Purpose Monte Carlo (MC) simulation studies, aimed at evaluating the magnitude of tissue heterogeneity in I-125 prostate permanent seed implant brachytherapy (BT), customarily use clinical post-implant CT images to generate a virtual representation of a realistic patient model (virtual patient model). Metallic artifact reduction (MAR) techniques and tissue assignment schemes (TAS) are implemented on the post-implant CT images to mollify metallic artifacts due to BT seeds and to assign tissue types to the voxels corresponding to the bright seed spots and streaking artifacts, respectively. The objective of this study is to assess the combined influence of MAR and TAS on MC absorbed dose calculations in post-implant CT-based phantoms. The virtual patient models used for I-125 prostate implant MC absorbed dose calculations in this study are derived from the CT images of an external radiotherapy prostate patient without BT seeds and prostatic calcifications, thus averting the need to implement MAR and TAS. Methods The geometry of the IsoSeed I25.S17plus source is validated by comparing the MC calculated results of the TG-43 parameters for the line source approximation with the TG-43U1S2 consensus data. Four MC absorbed dose calculations are performed in two virtual patient models using the egs_brachy MC code: (1) TG-43-based D-w,w-TG(43), (2) D-w,D-w-MBDC that accounts for interseed scattering and attenuation (ISA), (3) D-m,D-m that examines ISA and tissue heterogeneity by scoring absorbed dose in tissue, and (4) D-w,D-m that unlike D-m,D-m scores absorbed dose in water. The MC absorbed doses (1) and (2) are simulated in a TG-43 patient phantom derived by assigning the densities of every voxel to 1.00 g cm(-3) (water), whereas MC absorbed doses (3) and (4) are scored in the TG-186 patient phantom generated by mapping the mass density of each voxel to tissue according to a CT calibration curve. The MC absorbed doses calculated in this study are compared with VariSeed v8.0 calculated absorbed doses. To evaluate the dosimetric effect of MAR and TAS, the MC absorbed doses of this work (independent of MAR and TAS) are compared to the MC absorbed doses of different I-125 source models from previous studies that were calculated with different MC codes using post-implant CT-based phantoms generated by implementing MAR and TAS on post-implant CT images. Results The very good agreement of TG-43 parameters of this study and the published consensus data within 3% validates the geometry of the IsoSeed I25.S17plus source. For the clinical studies, the TG-43-based calculations show a D-90 overestimation of more than 4% compared to the more realistic MC methods due to ISA and tissue composition. The results of this work generally show few discrepancies with the post-implant CT-based dosimetry studies with respect to the D-90 absorbed dose metric parameter. These discrepancies are mainly Type B uncertainties due to the different I-125 source models and MC codes. Conclusions The implementation of MAR and TAS on post-implant CT images have no dosimetric effect on the I-125 prostate MC absorbed dose calculation in post-implant CT-based phantoms. |
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Address |
[Assam, Isong; Siebert, Frank-Andre] UKSH, Clin Radiotherapy Radiooncol, Campus Kiel, Kiel, Germany, Email: Isong.Assam@uksh.de |
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Thesis |
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Publisher |
Wiley |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0094-2405 |
ISBN |
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Conference |
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Notes |
WOS:000835807200001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5321 |
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Author |
Bernigaud, J.; Blanke, M.; de Medeiros Varzielas, I.; Talbert, J.; Zurita, J. |
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Title |
LHC signatures of tau-flavoured vector leptoquarks |
Type |
Journal Article |
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Year |
2022 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
08 |
Issue |
8 |
Pages |
127 - 31pp |
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Keywords |
New Light Particles; Specific BSM Phenomenology; Flavour Symmetries; Theories of Flavour |
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Abstract |
We consider the phenomenological signatures of Simplified Models of Flavourful Leptoquarks, whose Beyond-the-Standard Model (SM) couplings to fermion generations occur via textures that are well motivated from a broad class of ultraviolet flavour models (which we briefly review). We place particular emphasis on the study of the vector leptoquark Delta(mu) with assignments (3, 1, 2/3) under the SM's gauge symmetry, SU(3)(C) x SU(2)(L) x U(1)(Y), which has the tantalising possibility of explaining both R-K(*) and R-D(*) anomalies. Upon performing global likelihood scans of the leptoquark's coupling parameter space, focusing in particular on models with tree-level couplings to a single charged lepton species, we then provide confidence intervals and benchmark points preferred by low(er)-energy flavour data. Finally, we use these constraints to further evaluate the (promising) Large Hadron Collider (LHC) detection prospects of pairs of tau-flavoured Delta(mu), through their distinct (a)symmetric decay channels. Namely, we consider direct third-generation leptoquark and jets plus missing-energy searches at the LHC, which we find to be complementary. Depending on the simplified model under consideration, the direct searches constrain the Delta(mu), mass up to 1500-1770 GeV when the branching fraction of Delta(mu), is entirely to third-generation quarks (but are significantly reduced with decreased branching ratios to the third generation), whereas the missing-energy searches constrain the mass up to 1150-1700 GeV while being largely insensitive to the third-generation branching fraction. |
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Address |
[Bernigaud, Jordan; Blanke, Monika] Karlsruhe Inst Technol, Inst Astroparticle Phys IAP, Hermann Von Helmholtz Pl 1, D-76344 Eggenstein Leopoldshafen, Germany, Email: jordan.bernigaud@kit.edu; |
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Thesis |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1029-8479 |
ISBN |
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Area |
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Conference |
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Notes |
WOS:000840379400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5329 |
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