| Records |
| Author |
Oliver, S.; Vijande, J.; Tejedor-Aguilar, N.; Miro, R.; Rovira-Escutia, J.J.; Ballester, F.; Juste, B.; Carmona, V.; Felici, G.; Verdu, G.; Sanchis, E.; Conde, A.; Perez-Calatayud, J. |
| Title |
Monte Carlo flattening filter design to high energy intraoperative electron beam homogenization |
Type |
Journal Article |
Year  |
2023 |
Publication |
Radiation Physics and Chemistry |
Abbreviated Journal |
Radiat. Phys. Chem. |
| Volume |
212 |
Issue |
|
Pages |
111102 - 6pp |
| Keywords |
Intraoperative radiotherapy; Electron portable LinAc; Flattening filter; Dosimetry; Monte Carlo |
| Abstract |
Intraoperative radiotherapy using mobile linear accelerators is used for a wide variety of malignancies. However, when large fields are used in combination with high energies, a deterioration of the flatness dose profile is measured with respect to smaller fields and lower energies. Indeed, for the LIAC HWL of Sordina, this deterioration is observed for the 12 MeV beam combined with 10 cm (or larger) diameter applicator. Aimed to solve this problem, a flattening filter has been designed and validated evaluating the feasibility of its usage at the upper part of the applicator. The design of the filter was based on Monte Carlo simulations because of its accuracy in modeling components of clinical devices, among other purposes. The LIAC 10 cm diameter applicator was modeled and simulated independently by two different research groups using two different MC codes, reproducing the heterogeneity of the 12 MeV energy beam. Then, an iterative process of filter design was carried out. Finally, the MC designed conical filter with the optimal size and height to obtain the desired flattened beam was built in-house using a 3D printer. During the experimental validation of the applicator-filter, percentage depth dose, beam profiles, absolute and peripheral dose measurements were performed to demonstrate the effectiveness of the filter addition in the applicator. These measurements conclude that the beam has been flattened, from 5.9% with the standard configuration to 1.6% for the configuration with the filter, without significant increase of the peripheral dose. Consequently, the new filter-applicator LIAC configuration can be used also in a conventional surgery room. A reduction of 16% of the output dose and a reduction of 1.1 mm in the D50 of the percentage depth dose was measured with respect to the original configuration. This work is a proof-of-concept that demonstrates that it is possible to add a filter able to flatten the beam delivered by the Sordina LIAC HWL. Future studies will focus on more refined technical solutions fully compatible with the integrity of the applicator, including its sterilization, to be safely introduced in the clinical practice. |
| Address |
[Oliver, S.; Miro, R.; Juste, B.; Verdu, G.] Univ Polite cn Vale ncia, Inst Segur Ind Radiofis & Medioambiental ISIRYM, Cami Vera S-N, Valencia 46022, Spain, Email: gverdu@iqn.upv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Pergamon-Elsevier Science Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0969-806x |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:001026194900001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
5578 |
| Permanent link to this record |
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| Author |
Beaulieu, L.; Ballester, F.; Granero, D.; Tedgren, A.C.; Haworth, A.; Lowenstein, J.R.; Ma, Y.Z.; Mourtada, F.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Sloboda, R.S.; Smith, R.L.; Thomson, R.M.; Verhaegen, F.; Fonseca, G.; Vijande, J. |
| Title |
AAPM WGDCAB Report 372: A joint AAPM, ESTRO, ABG, and ABS report on commissioning of model-based dose calculation algorithms in brachytherapy |
Type |
Journal Article |
| Year |
2023 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
| Volume |
50 |
Issue |
8 |
Pages |
e946–e960 |
| Keywords |
brachytherapy; commissioning; dose calculation; model-based dose calculation; Monte Carlo; TG-186 |
| Abstract |
The introduction of model-based dose calculation algorithms (MBDCAs) in brachytherapy provides an opportunity for a more accurate dose calculation and opens the possibility for novel, innovative treatment modalities. The joint AAPM, ESTRO, and ABG Task Group 186 (TG-186) report provided guidance to early adopters. However, the commissioning aspect of these algorithms was described only in general terms with no quantitative goals. This report, from the Working Group on Model-Based Dose Calculation Algorithms in Brachytherapy, introduced a field-tested approach to MBDCA commissioning. It is based on a set of well-characterized test cases for which reference Monte Carlo (MC) and vendor-specific MBDCA dose distributions are available in a Digital Imaging and Communications in Medicine-Radiotherapy (DICOM-RT) format to the clinical users. The key elements of the TG-186 commissioning workflow are now described in detail, and quantitative goals are provided. This approach leverages the well-known Brachytherapy Source Registry jointly managed by the AAPM and the Imaging and Radiation Oncology Core (IROC) Houston Quality Assurance Center (with associated links at ESTRO) to provide open access to test cases as well as step-by-step user guides. While the current report is limited to the two most widely commercially available MBDCAs and only for Ir-192-based afterloading brachytherapy at this time, this report establishes a general framework that can easily be extended to other brachytherapy MBDCAs and brachytherapy sources. The AAPM, ESTRO, ABG, and ABS recommend that clinical medical physicists implement the workflow presented in this report to validate both the basic and the advanced dose calculation features of their commercial MBDCAs. Recommendations are also given to vendors to integrate advanced analysis tools into their brachytherapy treatment planning system to facilitate extensive dose comparisons. The use of the test cases for research and educational purposes is further encouraged. |
| Address |
[Beaulieu, Luc; Ma, Yunzhi] CHU Quebec Univ Laval, Serv Phys Med & Radioprotect, Quebec City, PQ, Canada, Email: beaulieu@phy.ulaval.ca |
| Corporate Author |
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Thesis |
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| Publisher |
Wiley |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0094-2405 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:001026540300001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
5579 |
| Permanent link to this record |
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| Author |
Pompa, F.; Schwetz, T.; Zhu, J.Y. |
| Title |
Impact of nuclear matrix element calculations for current and future neutrinoless double beta decay searches |
Type |
Journal Article |
| Year |
2023 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
| Volume |
06 |
Issue |
6 |
Pages |
104 - 29pp |
| Keywords |
Baryon; Lepton Number Violation; Neutrino Interactions |
| Abstract |
Nuclear matrix elements (NME) are a crucial input for the interpretation of neutrinoless double beta decay data. We consider a representative set of recent NME calculations from different methods and investigate the impact on the present bound on the effective Majorana mass m(& beta;& beta;) by performing a combined analysis of the available data as well as on the sensitivity reach of future projects. A crucial role is played by the recently discovered short-range contribution to the NME, induced by light Majorana neutrino masses. Depending on the NME model and the relative sign of the long- and short-range contributions, the current 3 & sigma; bound can change between m(& beta;& beta;)< 40 meV and 600 meV. The sign-uncertainty may either boost the sensitivity of next-generation experiments beyond the region for m(& beta;& beta;) predicted for inverted mass ordering or prevent even advanced setups to reach this region. Furthermore, we study the possibility to distinguish between different NME calculations by assuming a positive signal and by combining measurements from different isotopes. Such a discrimination will be impossible if the relative sign of the long- and short-range contribution remains unknown, but can become feasible if m(& beta;& beta;) & GSIM; 40 meV and if the relative sign is known to be positive. Sensitivities will be dominated by the advanced Ge-76 and Xe-136 setups assumed here, but NME model-discrimination improves if data from a third isotope is added, e.g., from Te-130 or Mo-100. |
| Address |
[Pompa, Federica] Univ Valencia, Inst Fis Corpuscular IFIC, CSIC, Parc Cientif UV, C Catedrat Jose Beltran 2, Paterna 46980, Spain, Email: zhujingyu@sjtu.edu.cn |
| Corporate Author |
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Thesis |
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| Publisher |
Springer |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1029-8479 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:001016276900003 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
5580 |
| Permanent link to this record |
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| Author |
Abreu, L.M.; Nery, E.S.; Correa, E.B.S. |
| Title |
Inverse magnetic catalysis and size-dependent effects on the chiral symmetry restoration |
Type |
Journal Article |
| Year |
2023 |
Publication |
European Physical Journal A |
Abbreviated Journal |
Eur. Phys. J. A |
| Volume |
59 |
Issue |
7 |
Pages |
157 - 12pp |
| Keywords |
|
| Abstract |
We investigate the combined finite-size and thermo-magnetic effects on the properties of the quark matter, in the context of the two-flavored Nambu-Jona-Lasinio model. In particular, by using the mean-field approximation and the Schwinger proper time method in a toroidal topology with periodic or antiperiodic conditions, we evaluate the chiral phase transition, the constituent quark mass and the thermal and spatial susceptibilities under the change of the size, temperature and strength of external magnetic field. To take into account the inverse magnetic catalysis phenomenon, we make use of a recently proposed magnetized coupling constant. The findings suggest that the observables are strongly affected by the variation of the variables and also by the periodicity of the boundary conditions, with the final outcomes depending on the balance of these competing phenomena. |
| Address |
[Abreu, Luciano M.; Nery, Elenilson S.] Univ Fed Bahia, Inst Fis, BR-40170115 Salvador, BA, Brazil, Email: luciano.abreu@ufba.br; |
| Corporate Author |
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Thesis |
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| Publisher |
Springer |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1434-6001 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:001029139600001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
5581 |
| Permanent link to this record |
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| Author |
Fadel, M.; Yadin, B.; Mao, Y.P.; Byrnes, T.; Gessner, M. |
| Title |
Multiparameter quantum metrology and mode entanglement with spatially split nonclassical spin ensembles |
Type |
Journal Article |
| Year |
2023 |
Publication |
New Journal of Physics |
Abbreviated Journal |
New J. Phys. |
| Volume |
25 |
Issue |
7 |
Pages |
073006 - 25pp |
| Keywords |
quantum metrology; Bose-Einstein condensates; spin-squeezing; Fisher information matrix; mode and particle entanglement |
| Abstract |
We identify the multiparameter sensitivity of entangled spin states, such as spin-squeezed and Dicke states that are spatially distributed into several addressable spatial modes. Analytical expressions for the spin-squeezing matrix of families of states that are accessible by current atomic experiments reveal the quantum gain in multiparameter metrology, as well as the optimal strategies to maximize the sensitivity gain for the estimation of any linear combination of parameters. We further study the mode entanglement of these states by deriving a witness for genuine k-partite mode entanglement from the spin-squeezing matrix. Our results highlight the advantage of mode entanglement for distributed sensing, and outline optimal protocols for multiparameter estimation with nonclassical spatially-distributed spin ensembles. We illustrate our findings with the design of a protocol for gradient sensing with a Bose-Einstein condensate in an entangled spin state in two modes. |
| Address |
[Fadel, Matteo] Swiss Fed Inst Technol, Dept Phys, CH-8093 Zurich, Switzerland, Email: fadelm@phys.ethz.ch; |
| Corporate Author |
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Thesis |
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| Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1367-2630 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:001026518600001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
yes |
| Call Number |
IFIC @ pastor @ |
Serial |
5582 |
| Permanent link to this record |
