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Author Caron, S.; Eckner, C.; Hendriks, L.; Johannesson, G.; Ruiz de Austri, R.; Zaharijas, G. url  doi
openurl 
  Title Mind the gap: the discrepancy between simulation and reality drives interpretations of the Galactic Center Excess Type Journal Article
  Year (down) 2023 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.  
  Volume 06 Issue 6 Pages 013 - 56pp  
  Keywords dark matter simulations; gamma ray experiments; Machine learning; millisecond pulsars  
  Abstract The Galactic Center Excess (GCE) in GeV gamma rays has been debated for over a decade, with the possibility that it might be due to dark matter annihilation or undetected point sources such as millisecond pulsars (MSPs). This study investigates how the gamma-ray emission model (-yEM) used in Galactic center analyses affects the interpretation of the GCE's nature. To address this issue, we construct an ultra-fast and powerful inference pipeline based on convolutional Deep Ensemble Networks. We explore the two main competing hypotheses for the GCE using a set of-yEMs with increasing parametric freedom. We calculate the fractional contribution (fsrc) of a dim population of MSPs to the total luminosity of the GCE and analyze its dependence on the complexity of the ryEM. For the simplest ryEM, we obtain fsrc = 0.10 f 0.07, while the most complex model yields fsrc = 0.79 f 0.24. In conclusion, we find that the statement about the nature of the GCE (dark matter or not) strongly depends on the assumed ryEM. The quoted results for fsrc do not account for the additional uncertainty arising from the fact that the observed gamma-ray sky is out-of-distribution concerning the investigated ryEM iterations. We quantify the reality gap between our ryEMs using deep-learning-based One-Class Deep Support Vector Data Description networks, revealing that all employed ryEMs have gaps to reality. Our study casts doubt on the validity of previous conclusions regarding the GCE and dark matter, and underscores the urgent need to account for the reality gap and consider previously overlooked “out of domain” uncertainties in future interpretations.  
  Address [Caron, Sascha; Hendriks, Luc] Radboud Univ Nijmegen, Theoret High Energy Phys, Heyendaalseweg 135, NL-6525 AJ Nijmegen, Netherlands, Email: scaron@nikhef.nl;  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1475-7516 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001025516000009 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5576  
Permanent link to this record
 

 
Author Maso-Ferrando, A.; Sanchis-Gual, N.; Font, J.A.; Olmo, G.J. url  doi
openurl 
  Title Birth of baby universes from gravitational collapse in a modified-gravity scenario Type Journal Article
  Year (down) 2023 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.  
  Volume 06 Issue 6 Pages 028 - 19pp  
  Keywords modified gravity; Wormholes  
  Abstract We consider equilibrium models of spherical boson stars in Palatini f (R) = R + CR2 gravity and study their collapse when perturbed. The Einstein-Klein-Gordon system is solved using a recently established correspondence in an Einstein frame representation. We find that, in that frame, the endpoint is a nonrotating black hole surrounded by a quasi -stationary cloud of scalar field. However, the dynamics in the f (R) frame is dramatically different. The innermost region of the collapsing object exhibits the formation of a finite -size, exponentially-expanding baby universe connected with the outer (parent) universe via a minimal area surface (a throat or umbilical cord). Our simulations indicate that this surface is at all times hidden inside a horizon, causally disconnecting the baby universe from observers above the horizon. The implications of our findings in other areas of gravitational physics are also discussed.  
  Address [Maso-Ferrando, Andreu; Olmo, Gonzalo J.] Univ Valencia, Ctr Mixto, CSIC, Dept Fis Teor, Valencia 46100, Spain, Email: andreu.maso@uv.es;  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1475-7516 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001025474200010 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5577  
Permanent link to this record
 

 
Author Oliver, S.; Vijande, J.; Tejedor-Aguilar, N.; Miro, R.; Rovira-Escutia, J.J.; Ballester, F.; Juste, B.; Carmona, V.; Felici, G.; Verdu, G.; Sanchis, E.; Conde, A.; Perez-Calatayud, J. doi  openurl
  Title Monte Carlo flattening filter design to high energy intraoperative electron beam homogenization Type Journal Article
  Year (down) 2023 Publication Radiation Physics and Chemistry Abbreviated Journal Radiat. Phys. Chem.  
  Volume 212 Issue Pages 111102 - 6pp  
  Keywords Intraoperative radiotherapy; Electron portable LinAc; Flattening filter; Dosimetry; Monte Carlo  
  Abstract Intraoperative radiotherapy using mobile linear accelerators is used for a wide variety of malignancies. However, when large fields are used in combination with high energies, a deterioration of the flatness dose profile is measured with respect to smaller fields and lower energies. Indeed, for the LIAC HWL of Sordina, this deterioration is observed for the 12 MeV beam combined with 10 cm (or larger) diameter applicator. Aimed to solve this problem, a flattening filter has been designed and validated evaluating the feasibility of its usage at the upper part of the applicator. The design of the filter was based on Monte Carlo simulations because of its accuracy in modeling components of clinical devices, among other purposes. The LIAC 10 cm diameter applicator was modeled and simulated independently by two different research groups using two different MC codes, reproducing the heterogeneity of the 12 MeV energy beam. Then, an iterative process of filter design was carried out. Finally, the MC designed conical filter with the optimal size and height to obtain the desired flattened beam was built in-house using a 3D printer. During the experimental validation of the applicator-filter, percentage depth dose, beam profiles, absolute and peripheral dose measurements were performed to demonstrate the effectiveness of the filter addition in the applicator. These measurements conclude that the beam has been flattened, from 5.9% with the standard configuration to 1.6% for the configuration with the filter, without significant increase of the peripheral dose. Consequently, the new filter-applicator LIAC configuration can be used also in a conventional surgery room. A reduction of 16% of the output dose and a reduction of 1.1 mm in the D50 of the percentage depth dose was measured with respect to the original configuration. This work is a proof-of-concept that demonstrates that it is possible to add a filter able to flatten the beam delivered by the Sordina LIAC HWL. Future studies will focus on more refined technical solutions fully compatible with the integrity of the applicator, including its sterilization, to be safely introduced in the clinical practice.  
  Address [Oliver, S.; Miro, R.; Juste, B.; Verdu, G.] Univ Polite cn Vale ncia, Inst Segur Ind Radiofis & Medioambiental ISIRYM, Cami Vera S-N, Valencia 46022, Spain, Email: gverdu@iqn.upv.es  
  Corporate Author Thesis  
  Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0969-806x ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001026194900001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5578  
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Author Beaulieu, L.; Ballester, F.; Granero, D.; Tedgren, A.C.; Haworth, A.; Lowenstein, J.R.; Ma, Y.Z.; Mourtada, F.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Sloboda, R.S.; Smith, R.L.; Thomson, R.M.; Verhaegen, F.; Fonseca, G.; Vijande, J. doi  openurl
  Title AAPM WGDCAB Report 372: A joint AAPM, ESTRO, ABG, and ABS report on commissioning of model-based dose calculation algorithms in brachytherapy Type Journal Article
  Year (down) 2023 Publication Medical Physics Abbreviated Journal Med. Phys.  
  Volume 50 Issue 8 Pages e946–e960  
  Keywords brachytherapy; commissioning; dose calculation; model-based dose calculation; Monte Carlo; TG-186  
  Abstract The introduction of model-based dose calculation algorithms (MBDCAs) in brachytherapy provides an opportunity for a more accurate dose calculation and opens the possibility for novel, innovative treatment modalities. The joint AAPM, ESTRO, and ABG Task Group 186 (TG-186) report provided guidance to early adopters. However, the commissioning aspect of these algorithms was described only in general terms with no quantitative goals. This report, from the Working Group on Model-Based Dose Calculation Algorithms in Brachytherapy, introduced a field-tested approach to MBDCA commissioning. It is based on a set of well-characterized test cases for which reference Monte Carlo (MC) and vendor-specific MBDCA dose distributions are available in a Digital Imaging and Communications in Medicine-Radiotherapy (DICOM-RT) format to the clinical users. The key elements of the TG-186 commissioning workflow are now described in detail, and quantitative goals are provided. This approach leverages the well-known Brachytherapy Source Registry jointly managed by the AAPM and the Imaging and Radiation Oncology Core (IROC) Houston Quality Assurance Center (with associated links at ESTRO) to provide open access to test cases as well as step-by-step user guides. While the current report is limited to the two most widely commercially available MBDCAs and only for Ir-192-based afterloading brachytherapy at this time, this report establishes a general framework that can easily be extended to other brachytherapy MBDCAs and brachytherapy sources. The AAPM, ESTRO, ABG, and ABS recommend that clinical medical physicists implement the workflow presented in this report to validate both the basic and the advanced dose calculation features of their commercial MBDCAs. Recommendations are also given to vendors to integrate advanced analysis tools into their brachytherapy treatment planning system to facilitate extensive dose comparisons. The use of the test cases for research and educational purposes is further encouraged.  
  Address [Beaulieu, Luc; Ma, Yunzhi] CHU Quebec Univ Laval, Serv Phys Med & Radioprotect, Quebec City, PQ, Canada, Email: beaulieu@phy.ulaval.ca  
  Corporate Author Thesis  
  Publisher Wiley Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0094-2405 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001026540300001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5579  
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Author Pompa, F.; Schwetz, T.; Zhu, J.Y. url  doi
openurl 
  Title Impact of nuclear matrix element calculations for current and future neutrinoless double beta decay searches Type Journal Article
  Year (down) 2023 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.  
  Volume 06 Issue 6 Pages 104 - 29pp  
  Keywords Baryon; Lepton Number Violation; Neutrino Interactions  
  Abstract Nuclear matrix elements (NME) are a crucial input for the interpretation of neutrinoless double beta decay data. We consider a representative set of recent NME calculations from different methods and investigate the impact on the present bound on the effective Majorana mass m(& beta;& beta;) by performing a combined analysis of the available data as well as on the sensitivity reach of future projects. A crucial role is played by the recently discovered short-range contribution to the NME, induced by light Majorana neutrino masses. Depending on the NME model and the relative sign of the long- and short-range contributions, the current 3 & sigma; bound can change between m(& beta;& beta;)< 40 meV and 600 meV. The sign-uncertainty may either boost the sensitivity of next-generation experiments beyond the region for m(& beta;& beta;) predicted for inverted mass ordering or prevent even advanced setups to reach this region. Furthermore, we study the possibility to distinguish between different NME calculations by assuming a positive signal and by combining measurements from different isotopes. Such a discrimination will be impossible if the relative sign of the long- and short-range contribution remains unknown, but can become feasible if m(& beta;& beta;) & GSIM; 40 meV and if the relative sign is known to be positive. Sensitivities will be dominated by the advanced Ge-76 and Xe-136 setups assumed here, but NME model-discrimination improves if data from a third isotope is added, e.g., from Te-130 or Mo-100.  
  Address [Pompa, Federica] Univ Valencia, Inst Fis Corpuscular IFIC, CSIC, Parc Cientif UV, C Catedrat Jose Beltran 2, Paterna 46980, Spain, Email: zhujingyu@sjtu.edu.cn  
  Corporate Author Thesis  
  Publisher Springer Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1029-8479 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001016276900003 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5580  
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