Abstract: Simple Summary There are no brachytherapy treatment planning systems (TPS) exclusively for the treatment of cervical tumours, so general-purpose TPSs are used. However, these treatments have some particular features concerning the treatment of other pathologies, especially in the case of exclusive use of MRI as an imaging modality and the presence of gynaecological applicators in combination with an interstitial part. That is why it is essential to review the latest versions of commercial TPSs to find the potential features to improve with the help of a group of experimented medical physicists and radiation oncologists. Furthermore, after reviewing the recent literature for advances applicable to cervical brachytherapy and through his own clinical experience, possible improvements are proposed to software providers for the development of new tools. Intracavitary brachytherapy (BT, Interventional Radiotherapy, IRT), plays an essential role in the curative intent of locally advanced cervical cancer, for which the conventional approach involves external beam radiotherapy with concurrent chemotherapy followed by BT. This work aims to review the different methodologies used by commercially available treatment planning systems (TPSs) in exclusive magnetic resonance imaging-based (MRI) cervix BT with interstitial component treatments. Practical aspects and improvements to be implemented into the TPSs are discussed. This review is based on the clinical expertise of a group of radiation oncologists and medical physicists and on interactive demos provided by the software manufacturers. The TPS versions considered include all the new tools currently in development for future commercial releases. The specialists from the supplier companies were asked to propose solutions to some of the challenges often encountered in a clinical environment through a questionnaire. The results include not only such answers but also comments by the authors that, in their opinion, could help solve the challenges covered in these questions. This study summarizes the possibilities offered nowadays by commercial TPSs, highlighting the absence of some useful tools that would notably improve the planning of MR-based interstitial component cervix brachytherapy.

Abstract: We study the (B) over bar (0)(s) -> J/psi f(0)(980) and (B) over bar (0)(s) -> J/psi a(0)(980) reactions, and pay attention to the different sources of isospin violation and mixing of f(0)(980) and a(0)(980) resonances where these resonances are dynamically generated from meson-meson interactions. We fmd that the main cause of isospin violation is isospin breaking in the meson-meson transition T matrices, and the other source is that the loops involving kaons in the production mechanism do not cancel due to the different masses of charged and neutral kaons. We obtain a branching ratio for a(0)(980) production of the order of 5 x 10(-6) . Future experiments can address this problem, and the production rate and shape of the pi(0)eta mass distribution will definitely help to better understand the nature of scalar resonances.

Abstract: The holographic graviton soft-wall model, introduced to describe the spectrum of scalar and tensor glueballs, is improved to incorporate the realization of chiral-symmetry as in QCD. Such a goal is achieved by including the longitudinal dynamics of QCD into the scheme. Using the relation between AdS/QCD and light-front dynamics, we construct the appropriate wave function for the pion which is used to calculate several pion observables. The comparison of our results with phenomenology is remarkably successful.