Abstract: Hadron therapy is a radiotherapy modality which offers a precise energy deposition to the tumors and a dose reduction to healthy tissue as compared to conventional methods. However, methods for real-time monitoring are required to ensure that the radiation dose is deposited on the target. The IRIS group of IFIC-Valencia developed a Compton camera prototype for this purpose, intending to image the Prompt Gammas emitted by the tissue during irradiation. The system detectors are composed of Lanthanum (III) bromide scintillator crystals coupled to silicon photomultipliers. After an initial characterization in the laboratory, in order to assess the system capabilities for future experiments in proton therapy centers, different tests were carried out in two facilities: PARTREC (Groningen, The Netherlands) and the CNA cyclotron (Sevilla, Spain). Characterization studies performed at PARTREC indicated that the detectors linearity was improved with respect to the previous version and an energy resolution of 5.2 % FWHM at 511 keV was achieved. Moreover, the imaging capabilities of the system were evaluated with a line source of 68Ge and a point-like source of 241Am-9Be. Images at 4.439 MeV were obtained from irradiation of a graphite target with an 18 MeV proton beam at CNA, to perform a study of the system potential to detect shifts at different intensities. In this sense, the system was able to distinguish 1 mm variations in the target position at different beam current intensities for measurement times of 1800 and 600 s.

Abstract: A search for nonresonant Higgs boson pair production in the b (b) over bar gamma gamma final state is performed using 140 fb(-1) of proton-proton collisions at a centre-of-mass energy of 13 TeV recorded by the ATLAS detector at the CERN Large Hadron Collider. This analysis supersedes and expands upon the previous nonresonant ATLAS results in this final state based on the same data sample. The analysis strategy is optimised to probe anomalous values not only of the Higgs (H) boson self-coupling modifier kappa(lambda) but also of the quartic HHVV (V = W, Z) coupling modifier kappa(2V). No significant excess above the expected background from Standard Model processes is observed. An observed upper limit mu(HH) < 4.0 is set at 95% confidence level on the Higgs boson pair production cross-section normalised to its Standard Model prediction. The 95% confidence intervals for the coupling modifiers are -1.4 < kappa(lambda) < 6.9 and -0.5 < kappa(2V) < 2.7, assuming all other Higgs boson couplings except the one under study are fixed to the Standard Model predictions. The results are interpreted in the Standard Model effective field theory and Higgs effective field theory frameworks in terms of constraints on the couplings of anomalous Higgs boson (self-)interactions.

Abstract: The first measurement of the Z boson production cross-section at centre-of-mass energy v s = 5.02TeV in the forward region is reported, using pp collision data collected by the LHCb experiment in year 2017, corresponding to an integrated luminosity of 100 +/- 2 pb-1. The production cross-section is measured for final-state muons in the pseudorapidity range 2.0 <. < 4.5 with transverse momentum pT > 20 GeV/c. The integrated cross-section is determined to be sZ.mu+mu- = 39.6 +/- 0.7(stat) +/- 0.6(syst) +/- 0.8(lumi) pb for the di-muon invariant mass in the range 60 < M μμ< 120 GeV/c2. This result and the differential cross-section results are in good agreement with theoretical predictions at next-to-next-to-leading order in the strong coupling constant. Based on a previous LHCb measurement of the Z boson production cross-section in pPb collisions at v sNN = 5.02TeV, the nuclear modification factor RpPb is measured for the first time at this energy. The measured values are 1.2+0.5 -0.3(stat) +/- 0.1(syst) in the forward region (1.53 < y* μ< 4.03) and 3.6+1.6 -0.9(stat)+/- 0.2(syst) in the backward region (-4.97 < y* μ< -2.47), where y* μrepresents the muon rapidity in the centre-of-mass frame.